Search Results (2,262)

Climate change poses significant challenges to the operation and safety of dam and reservoir (D&R) systems, particularly in regions characterized by water scarcity and high climate variability. This study presents a structured methodology for climate risk assessment that integrates regional climate projections, system-specific thresholds, and a semi-quantitative risk matrix approach. A key innovation is the explicit linkage between climate indicators and system performance through physically based thresholds, combined with empirically derived exceedance probabilities from high-resolution climate projections. The methodology is applied to the Almopeos D&R system in northern Greece, using an ensemble of statistically downscaled CMIP6 simulations under two emission scenarios (SSP2-4.5 and SSP5-8.5) and two future periods (2041–2060 and 2081–2100). Three climate indicators are analyzed: TX35 (temperature extremes), CDD (consecutive dry days), and Rx1day (extreme precipitation). Results indicate that temperature increase is the dominant climate risk hazard, leading to increased irrigation demand and reduced system reliability, with risks classified as high to very high. Drought conditions represent a secondary but important risk, becoming critical during prolonged dry periods affecting reservoir storage, while extreme precipitation events exhibit low likelihood but potentially high consequences for dam safety. Adaptation measures are prioritized using a qualitative multi-criteria approach, highlighting the effectiveness of operational measures, while structural and monitoring interventions remain essential for ensuring system safety. The proposed methodology provides a transparent and transferable framework for climate-resilient planning of water infrastructure systems. Full article

Understanding of carrot growth dynamics and ecophysiological functioning in tropical highland environments remains limited, despite the crop’s productive importance in the Colombian Andean region. This study aimed to characterize biomass accumulation and partitioning, as well as the photosynthetic response to radiation, in two carrot (Daucus carota L.) cultivars (Berlicum- and Flakkee-type) grown under high-altitude Andean tropical conditions in Rionegro, Antioquia. To account for field spatial heterogeneity, four beds were used as blocks, and both cultivars were evaluated in parallel under comparable field conditions. Weekly destructive samplings were performed to quantify total dry biomass, shoot biomass, root biomass, leaf number, and leaf area. In addition, the response of net CO₂ assimilation to photosynthetically active radiation was evaluated using a portable gas-exchange system. Total and root biomass were described using logistic models, shoot biomass using a Gaussian model, and the photosynthetic response using an exponential model. Berlicum showed higher biomass accumulation, whereas Flakkee exhibited an earlier response of growth and photosynthetic activity. In both cultivars, the highest functional capacity was concentrated in stage III, coinciding with the strengthening of the storage-root sink. Overall, the results indicate contrasting temporal patterns in biomass partitioning and photosynthetic performance between the two carrot cultivars and provide a useful ecophysiological framework for interpreting crop management and harvest timing under high-altitude Andean tropical conditions. Full article

It is well known that gas sensor responses are affected by the presence of humidity in the analyzed gas. This is particularly true when dealing with biological fluid samples, whose high moisture content interferes with the adsorption of the trace volatile organic compounds (VOCs) on the sensors’ active layer. To address this challenge, this study focuses on designing and testing a novel sampling system for the dehumidification of biological fluid headspace to be characterized by an electronic nose (e-Nose). Such a system, based on the use of disposable polymeric sampling bags purged with dry air, exploits the polymers’ permeability to water vapor to reduce sample humidity. Tested materials included Nalophan^TM (20 μm), high-density polyethylene (HDPE, 8, 9, 10 and 11 μm), low-density polyethylene (LDPE, 12 and 50 μm), and biodegradable polyester (Bio-PS, 15 μm). First, dehumidification performance was characterized as a function of dry air flow rate and film type. A purge of 1 L/min accelerated the sample humidity removal compared to passive storage of bags from >2 h to <1 h (from 80% to 20% RH). Second, a mass-balance model was applied to dedicated experiments to decouple water losses due to diffusion and adsorption, showing that diffusion through the polymer wall dominates, while adsorption occurs in the early stages of conditioning. Third, because these materials are not selectively permeable to water, potential loss of water-soluble VOCs during dehumidification was investigated. Pooled urine headspace samples—both raw and spiked with a metabolite mix of VOCs—were dried using each material and analyzed using a photo-ionization detector (PID) and an e-Nose. Results were compared against a Nafion^TM dryer. Comparison was based on the e-Nose’s ability to discriminate between pooled vs. spiked samples and reveal real-life metabolomic changes. Nalophan^TM bags and Nafion^TM dryer provided the highest VOC fingerprint to support discrimination by the e-Nose, while Bio-PS provided the fastest sample dehumidification. The proposed bag-based system offers a cost-effective, disposable, and contamination-free solution to humidity interference in e-Noses. Full article

The multi-cycle high-rate injection and production operations in Underground Gas Storage (UGS) facilities converted from depleted fracture-pore carbonate gas reservoirs induce complex rock–fluid interactions that threaten long-term integrity and performance. This study experimentally investigates the petrophysical responses of the Xiangguosi (XGS) UGS carbonate reservoirs in China using multi-cycle stress sensitivity tests, fines migration experiments, and water evaporation–salt precipitation analyses. SEM observations distinguish the contributions of crack closure and matrix compression to permeability evolution. Results show a sharp contrast in mechanical damage: high-quality rocks present negligible permanent deformation (<8% Young’s modulus reduction), whereas poor-quality rocks suffer catastrophic deterioration (>60%). Fines migration exhibits a three-stage behavior under cyclic flow, with water saturation significantly aggravating permeability impairment. A critical salinity threshold (220,000 ppm) is identified for the transition between drying-enhanced storage and salt plugging. Permeability declines sharply despite a slight porosity increase due to selective salt clogging of key pore throats, revealing a clear porosity–permeability decoupling. Salt deposition under movable water conditions can reduce UGS capacity by up to 1.45%. Reservoir heterogeneity, microfractures, karst structures, and initial petrophysical properties dominate the storage and flow space evolution. This work provides a predictive framework for optimizing injection–production strategies and improving the performance of complex carbonate UGS. Full article

Understanding dry-out-induced weakening of reservoir and caprock rocks driven by gas displacement is critical for ensuring the operational safety and efficiency of underground gas storage (UGS). Using core samples from the Xiangguosi UGS collected from different regions and stratigraphic intervals, we quantify the evolution of dynamic elastic parameters during simulated downhole dry-out with a joint ultrasonic and nuclear magnetic resonance (NMR) monitoring system. The results show that as water saturation (S_w) decreases, the dynamic bulk modulus (K_d) and P-wave velocity (V_p) decline by varying degrees across specimens, with reductions ranging from 3.0% to 50.48% and from 1.34% to 17.56%, respectively, whereas the dynamic shear modulus (G_d) and S-wave velocity (V_s) show only minor variations throughout the process. These findings demonstrate that the sensitivity of dynamic parameters to dry-out is strongly specimen-dependent. Further analysis indicates that the dry-out response is highly variable and depends on a combination of petrophysical properties. Among these, the heterogeneity of the initial pore structure acts as an important factor, with its influence shaped by mineralogy and bulk frame rigidity. Cores with multimodal pore size distributions and well-developed macropores (long T₂ components) respond more strongly to dry-out, whereas higher clay mineral contents tend to mitigate modulus degradation by retaining water under stronger capillary confinement. Based on these observations, we propose a conceptual model of pore support and skeleton constraint. The model suggests that dry-out weakening arises from a progressive loss of pore fluid volumetric support to the rock skeleton as free water is preferentially displaced from meso- and macropores. These findings provide key experimental evidence and mechanistic insights for using geophysical methods to monitor dry-out zone expansion and to assess long-term formation stability in UGS. Full article

Background/Objectives: In several contexts, Dried Sample Spot Devices (DSSDs) offer a convenient and safe alternative for sampling, storage, and shipment, allowing the transport and storage of biological samples at room temperature, reducing shipment costs and improving access to diagnostics in faraway sites. This can be pivotal for the use of the therapeutic drug monitoring of anti-HIV treatment: therefore, this study aimed to develop and validate a UHPLC–MS/MS method for the simultaneous quantification of 12 antiretroviral drugs, including the recently introduced long-acting agents, in Dry Plasma Spots (DPSs). Methods: First, 100 µL of plasma sample and 100 µL of internal standard solution were spotted on each DSSD. After complete drying, DPSs were added with an acidifying solution (ammonium acetate buffer pH 4), and then, each sample underwent extraction with hexane-dichloromethane 50:50 (v/v). After tumbling, the organic phase was evaporated and reconstituted for injection. An Acquity UPLC HSS T3 1.8 µm, 2.1 × 150 mm column at 50 °C enabled separation, performed using H₂O + F.A. 0.05% (phase A) and ACN + F.A. 0.05% (phase B) as the mobile phase in gradient elution mode, for a total run time of 15 min. Results: The method was validated over the clinically relevant concentration ranges. For all quality control levels, accuracies ranged from 98.2% to 114.1%, and intra-day and inter-day RSD values ranged from 2.7% to 9.7% and 5.2% to 13.9%, respectively. All analytes demonstrated satisfactory short- and long-term stability in DPSs, confirming the suitability of shipment and storage at room temperature. Conclusions: The method demonstrated robustness and reproducibility in accordance with FDA and EMA guidelines. It ensures satisfactory accuracy and rapid analysis, supporting its application in clinical practice, including for monitoring the newest long-acting drugs. Full article

Understanding drought and water availability requires integrating multiple components of the hydrological cycle. Satellite observations enable consistent monitoring of water storage, groundwater variability, and water budget components at continental scales. This study synthesises results from several satellite-based analyses to examine hydrological signals across Europe within the Köppen–Geiger climate zones. Indicators were analysed jointly, including the Combined Climatologic Deviation Index (CCDI), Water Budget (WB), Water Storage Deficit Index (WSDI), and Groundwater Drought Index (GDI). The comparison of these indices reveals consistent spatial and temporal patterns of water deficit across Europe, with the strongest drying signals observed in temperate and Mediterranean regions. In contrast, northern climatic zones show higher retention capacity. The integrated approach highlights relationships among groundwater variability, water storage anomalies, climate anomalies, and water budget dynamics, providing a broader perspective on hydrological responses to climate variability. The results demonstrate the value of multi-indicator satellite analysis for large-scale drought monitoring and water resource assessment. Full article

Background/Objectives: Cannabidiol (CBD) has emerged as a potential therapeutic agent for respiratory disorders, including asthma and chronic obstructive pulmonary disease. However, its clinical translation via pulmonary delivery is limited by poor aqueous solubility, chemical instability, and low local bioavailability. This study aimed to develop and optimize a sodium stearate (NaSt)-based spray-dried dry powder inhaler (DPI) formulation to enhance the aerosol performance, dissolution, and storage stability of CBD. Methods: CBD microparticles were prepared by spray drying using NaSt as the primary excipient. The feed preparation method, spray-drying parameters, and CBD:NaSt ratios were systematically optimized. The resulting powders were evaluated for aerodynamic properties using cascade impaction, dissolution behavior in simulated lung fluid, solid-state characteristics, and accelerated stability under stress conditions. Results: The optimized formulation, SD-4, a spray-dried CBD:NaSt formulation prepared at a 20:80 weight ratio using Process B, demonstrated excellent aerosolization performance, with a fine particle fraction (FPF) exceeding 50% and a mass median aerodynamic diameter (MMAD) of 5.08 ± 0.1 μm. Dissolution testing revealed more than a three-fold increase in drug release compared with raw CBD, attributed to amorphous dispersion within the NaSt matrix and surfactant-induced micellization. Accelerated stability studies confirmed improved retention of the amorphous state and drug content, while antioxidant incorporation further reduced oxidative degradation. Conclusions: The NaSt-based spray-dried formulation significantly improved aerosol deposition efficiency, dissolution rate, and physicochemical stability of CBD. This formulation strategy may provide a promising platform for pulmonary delivery of poorly water-soluble compounds. Full article

Cryoprotectants are used to protect biological cells from damage caused by freezing. This study aimed to determine the effect of various types of cryoprotectant on the survival rate of freeze-dried Limosilactobacillus frumenti (L. frumenti) used as a starter culture for cucumber fermentation. Mixtures of freeze-dried L. frumenti with cryoprotectants were prepared using two different ratios (1:2 and 1:10). The survival rate of L. frumenti was determined by viable cell counts (CFU/mL) after freeze-drying, and fermentation performance was evaluated in terms of physicochemical quality and sensory evaluation. Skim milk proved to be the most effective cryoprotectant, yielding a survival rate of approximately 70% (70.07% for the 1:10 ratio and 70.01% for the 1:2 ratio) after 24 h of storage at 4 °C. Sensory evaluation indicated that cucumber fermentation prepared with freeze-dried L. frumenti mixed with skim milk (ratio 1:10) was the most preferred by panelists. Full article

Decarbonising greenhouse food production requires improvements in thermal management, energy efficiency, and system integration. Greenhouse energy demand is shaped by coupled heat and mass transfer processes, particularly envelope performance, ventilation, and latent heat associated with humidity control. This article synthesises recent advances in greenhouse microclimate control with emphasis on heat transfer, low-carbon heating and cooling, thermal storage, renewable and waste heat integration, and advanced modelling and control approaches. The review shows that humidity control and latent load management are primary drivers of winter energy use, as moisture removal through ventilation and dehumidification directly increases the sensible heating required to maintain indoor temperature setpoints. When assessed using realistic psychrometric relationships, ventilation and dehumidification can dominate peak heating demand and seasonal consumption. The performance of heat pumps, storage systems, semi-closed greenhouse concepts, and renewable heat pathways depends on how thermal loads are defined, how system boundaries are set, and how technologies are integrated in operation. Digital twins, predictive control, and hybrid physics-data models are increasingly used to manage variability in weather, energy prices, and infrastructure constraints. Greenhouse decarbonisation cannot be treated as a simple substitution of energy sources. System performance depends on coordinated design and operation, including heat recovery, moisture removal, and integration of supply technologies. Semi-closed and heat recovery-based configurations can reduce the ventilation–heating penalty and lower primary energy demand compared with vent-to-dry approaches. Long-term market projections suggest that the commercial greenhouse sector could expand substantially by 2050 under plausible growth scenarios, reflecting increased capital investment rather than a proportional rise in global food output. Net-zero greenhouse production is achievable through combined improvements in thermal management, electrification, and renewable energy integration. However, large-scale deployment depends on consistent modelling assumptions, credible economic assessment, and alignment with heat and CO₂ supply infrastructure. The transition is therefore shaped by system integration and planning as much as by individual technologies. Full article

Tailings management presents a critical challenge for the mining industry, particularly in mountainous regions with high seismicity and steep slopes. This article presents the development and design criteria for dry stacking of filtered tailings as a sustainable and safe alternative to conventional slurry tailings storage facilities (TSFs). The study focuses on the extreme conditions of a mountainous location characterized by complex topography with 10% slopes, space constraints, and significant seismic activity defined by a peak ground acceleration (PGA) of 0.3 g. The design methodology, which incorporates layered compaction of the filtered tailings to achieve a geotechnically stable structure, is detailed for a filtered TSF consisting of 7 terraces, each 10 m high, reaching a total height of 70 m. This approach minimizes the risk of liquefaction and prepares the filtered tailings surface for progressive closure, with unit operating costs (OPEX) of 2.5 USD/t. The results of the physical stability analysis confirm the viability of this solution: pseudo-static stability analysis yielded a safety factor of 1.22, demonstrating a significant reduction in water consumption and potential environmental impact. It is concluded that the dry disposal of filtered tailings is a technically robust option for tailings management in extreme mountainous environments, offering greater long-term safety guarantees and facilitating landscape integration, thus setting a precedent for mining projects in similar geographies. Full article

Postharvest processing plays an important role in improving the quality and storage stability of mature fresh Amomum villosum Lour. (A. villosum). We investigated the effects of seven common drying methods (electric baking drying (EBD), heat pump drying, sun drying after heat pump drying, shade drying, hot air drying, sun drying, and freeze drying) on the volatile components of Amomum villosum. To discriminate different samples and identify key markers, chemometric techniques, including principal component analysis (PCA) and orthogonal partial least squares discriminant analysis (OPLS-DA), were applied to Chromatography–Mass Spectrometer (GC-MS) data of 70 identified metabolites. As an unsupervised method, PCA was first utilized to observe the overall clustering tendency of 21 samples, showing clear dispersion among seven groups with a slight overlap in the samples from sun drying after heat pump drying and hot air drying. To improve discrimination accuracy, the OPLS-DA model was further established as a supervised method. Its reliability was verified by permutation tests and cross-validation, which confirmed the absence of overfitting (R² and Q² intercepts with the vertical axis were <1 and <0, respectively). S-plots combined with variable importance in projection (VIP) values greater than 1 were used to screen differential metabolites, and camphor, borneol, and bornyl acetate were identified as the key discriminant markers for the samples obtained by different drying methods. Consequently, camphor, borneol and bornyl acetate, which are regarded as quality markers of A. villosum, were determined by gas chromatography (GC) to identify the optimal drying method for fresh A. villosum. The results showed that the content of the quality markers in A. villosum obtained by the seven drying methods outclass the standards of the Chinese Pharmacopoeia.Comprehensively considering the experimental results and the convenience and operability of the drying process, EBD is the most suitable drying process of A. villosum for popularization and application. It is on account of the shortest drying time among the seven drying methods, which only took 21.63 h to complete the drying of fresh A. villosum. Besides that, the quality control parameters in the content of bornyl acetate, camphor, borneol and the essential oil of A. villosum obtained by EBD were far more than the standards stipulated in the pharmacopeia. Full article

To address the trade-off between storage stability and curing reactivity in NCO-terminated waterborne polyurethane (WPU) systems, a solvent-free WPU emulsion with dual-curing characteristics was developed using vanillin (VAN) and 2-hydroxyethyl acrylate/pentaerythritol triacrylate (HEA/PETA). Hexamethylene diisocyanate (HDI) and 2,2-bis(hydroxymethyl)butyric acid (DMBA) were used as the isocyanate component and internal hydrophilic moiety, respectively, to prepare a self-dispersible polyurethane prepolymer. VAN was introduced as a latent isocyanate-related component, while HEA/PETA served as acrylate-bearing reactive modifiers, followed by self-emulsification to form a stable aqueous dispersion. The prepolymer structure, curing behavior, and adhesive performance on bamboo substrates were systematically investigated. The results supported the successful introduction of VAN-derived structures into the polyurethane chains and the retention of polymerizable C=C bonds from HEA/PETA. Thermal analysis suggested dual-curing behavior with two distinguishable thermal events, involving lower-temperature polymerization of unsaturated groups and a VAN-related higher-temperature reaction. The resulting WPU exhibited dry and wet shear strengths above 23 MPa and 9 MPa, respectively. These findings demonstrate a feasible strategy for integrating emulsion stability, staged curing, and adhesive performance in solvent-free WPU systems. Full article

Fermented Miang (Camellia sinensis var. assamica) serves as a valuable source of bioactive polyphenols and probiotic-associated components. This study characterized the catechin composition of fermented Miang extracts and evaluated their antioxidant capacity and suitability for cosmetic formulations. High-performance liquid chromatography (HPLC) analysis showed that epigallocatechin gallate (EGCG) was the predominant catechin (7.00 ± 0.93 mg/g dry weight), followed by catechin (C), epicatechin (EC), epicatechin gallate (ECG), and epigallocatechin (EGC). The extracts remained physically and chemically stable for at least three months under various storage conditions, with the dried extract form offering advantages for handling and formulation. Fermentation duration significantly influenced phenolic accumulation and antioxidant activity, with four-month fermentation showing the highest activity. Prototype cleansing formulations, including transparent/opaque soap bars, liquid soap, and shampoo containing fermented Miang extract, exhibited acceptable physicochemical characteristics and retained antioxidant function. These findings highlight fermented Miang as a promising natural ingredient for antioxidant and probiotic-inspired cosmetic applications. Full article

The synergistic utilization of waste plastics and tires in asphalt modification is a highly promising sustainable strategy. However, the differential impacts of distinct plastic molecular architectures on the performance and network evolution of rubber-modified asphalt remain fundamentally unclear. This study systematically investigated the physical, rheological, and microstructural properties of composite asphalts modified with desulfurized rubber powder (DRP) and four representative plastics: polyethylene (PE), styrene–isoprene–styrene (SIS), styrene–ethylene–butylene–styrene (SEBS), and styrene–butadiene–styrene (SBS). Furthermore, the pavement performance of the asphalt mixtures prepared via dry and wet methods was comparatively evaluated. Microstructural and spectroscopic analyses revealed that the composite modification was primarily governed by physical blending and swelling. The non-polar, semi-crystalline PE resulted in severe phase separation and extreme low-temperature brittleness. Conversely, the saturated hydrogenated mid-blocks of SEBS endowed the asphalt with the highest high-temperature rutting resistance but severely compromised its low-temperature stress relaxation. Remarkably, SBS interacted synergistically with DRP to form a highly homogeneous and densely interwoven three-dimensional network, thereby achieving an optimal viscoelastic balance, outstanding storage stability, and superior low-temperature ductility. Pavement performance tests further demonstrated that the wet method significantly outperformed the dry method for block copolymers by facilitating sufficient pre-swelling. Overall, the SBS-DRP composite-modified asphalt prepared via the wet method exhibited the most exceptional and balanced comprehensive pavement performance, providing a robust theoretical foundation for the sustainable and high-value recycling of multi-source solid wastes in paving engineering. Full article