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17 pages, 2270 KB  
Article
Guided Implant Surgery in Oral Cancer Patients: Initial Clinical Experience from an Academic Point-of-Care Manufacturing Unit
by Manuel Tousidonis, Jose-Ignacio Salmeron, Santiago Ochandiano, Ruben Perez-Mañanes, Estela Gomez-Larren, Elena Aguilera-Jimenez, Carla de Gregorio-Bermejo, Diego Fernández-Acosta, Borja Gonzalez-Moure, Saad Khayat and Carlos Navarro-Cuellar
Medicina 2026, 62(1), 151; https://doi.org/10.3390/medicina62010151 - 12 Jan 2026
Viewed by 170
Abstract
Background and Objectives: Implant-supported rehabilitation after oral cancer surgery remains technically and biologically demanding due to altered anatomy, scar tissue, and prior radiotherapy. Digital workflows and hospital-based point-of-care (POC) manufacturing now enable personalized, prosthetically driven implant placement with static surgical guides fabricated [...] Read more.
Background and Objectives: Implant-supported rehabilitation after oral cancer surgery remains technically and biologically demanding due to altered anatomy, scar tissue, and prior radiotherapy. Digital workflows and hospital-based point-of-care (POC) manufacturing now enable personalized, prosthetically driven implant placement with static surgical guides fabricated within the clinical environment. This study reports the initial clinical experience of an academic POC manufacturing unit (UPAM3D) implementing static guided implant surgery in oral cancer patients and compares this approach with conventional outsourcing and dynamic navigation methods. Materials and Methods: A retrospective review of 30 consecutive cases (2021–2024) treated with POC-manufactured static guides was conducted using data from the UPAM3D registry. Each record included design, fabrication, and sterilization parameters compliant with ISO 13485 standards. Demographic, surgical, and prosthetic variables were analyzed, including anatomical site (maxilla or mandible), guide type, material, radiotherapy history, number of Ticare Implants®, and loading strategy. Results: All surgical guides were designed and 3D printed in-house using biocompatible resins (BioMed Clear, Dental SG, or LT Clear). The annual number of POC procedures increased progressively (2 → 6 → 6 → 16). Most cases involved oncologic reconstructions of the maxilla or mandible, including irradiated fields. When recorded, primary stability values (mean ISQ ≈ 79) allowed immediate or early loading (ISQ ≥ 70). No major intraoperative or postoperative complications occurred, and all guides met sterilization and traceability standards. Conclusions: Point-of-care manufacturing enables efficient, accurate, and patient-specific guided implant rehabilitation after oral cancer surgery, optimizing functional and esthetic outcomes while reducing procedural time and dependence on external providers. Integrating this process into clinical workflows supports personalized treatment planning and broadens access to advanced implant reconstruction within multidisciplinary oncology care. Full article
(This article belongs to the Special Issue Research on Oral and Maxillofacial Surgery)
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23 pages, 935 KB  
Review
Integration and Innovation in Digital Implantology–Part II: Emerging Technologies and Converging Workflows: A Narrative Review
by Tommaso Lombardi and Alexandre Perez
Appl. Sci. 2025, 15(23), 12789; https://doi.org/10.3390/app152312789 - 3 Dec 2025
Viewed by 813
Abstract
Emerging artificial intelligence (AI) and robotic surgical technologies have the potential to influence digital implant dentistry substantially. As a narrative review, and building on the foundations outlined in Part I, which described current digital tools and workflows alongside their persistent interface-related limitations, this [...] Read more.
Emerging artificial intelligence (AI) and robotic surgical technologies have the potential to influence digital implant dentistry substantially. As a narrative review, and building on the foundations outlined in Part I, which described current digital tools and workflows alongside their persistent interface-related limitations, this second part examines how AI and robotics may overcome these barriers. This synthesis is based on peer-reviewed literature published between 2020 and 2025, identified through searches in PubMed, Scopus, and Web of Science. Current evidence suggests that AI-based approaches, including rule-based systems, traditional machine learning, and deep learning, may achieve expert-level performance in diagnostic imaging, multimodal data registration, virtual patient model generation, implant planning, prosthetic design, and digital smile design. These methods offer substantial improvements in efficiency, reproducibility, and accuracy while reducing reliance on manual data handling across software, datasets, and workflow interfaces. In parallel, robotic-assisted implant surgery has advanced from surgeon-guided systems to semi-autonomous and fully autonomous platforms, with the potential to provide enhanced surgical precision and reduce operator dependency compared with conventional static or dynamic navigation. Several of these technologies have already reached early stages of clinical deployment, although important challenges remain regarding interoperability, standardization, validation, and the continuing need for human oversight. Together, these innovations may enable the gradual convergence of digital technologies, real-time-assisted, unified, end-to-end implant prosthodontic workflows, and gradual automation, while acknowledging that full automation remains a longer-term prospect. By synthesizing current evidence and proof-of-concept applications, this review aims to provide clinicians with a comprehensive overview of the AI and robotics toolkit relevant to implant dentistry and to outline both the opportunities and remaining limitations of these disruptive technologies as the field progresses towards seamless, fully integrated treatment pathways. Full article
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16 pages, 621 KB  
Article
Patients’ Knowledge and Perceptions Towards Digital Technologies in Dentistry: A Cross-Sectional Study
by Aliona Dodi, Alecsandru Ionescu, Mihaela Anca Marin and Marina Imre
Dent. J. 2025, 13(12), 569; https://doi.org/10.3390/dj13120569 - 2 Dec 2025
Viewed by 381
Abstract
Background/Objectives: The accelerated digitalisation of dental practice is significantly influencing how patients perceive and accept modern treatments. This study uses a structured questionnaire to evaluate patients’ knowledge of, and attitudes towards, digital technologies in dentistry, adopting an original, patient-centred perspective within routine clinical [...] Read more.
Background/Objectives: The accelerated digitalisation of dental practice is significantly influencing how patients perceive and accept modern treatments. This study uses a structured questionnaire to evaluate patients’ knowledge of, and attitudes towards, digital technologies in dentistry, adopting an original, patient-centred perspective within routine clinical settings. Methods: Non-parametric statistical methods (Mann–Whitney U test, Kruskal–Wallis H test and Spearman correlations) were employed to analyse the responses of 397 participants. To reduce selection bias, a systematic sampling technique was employed, and thorough validation ensured the consistency of the instrument. The questionnaire covered socio-demographic information, prior dental experience and opinions regarding specific digital applications (intraoral scanning (IOS), cone-beam computed tomography (CBCT), CAD-CAM workflows, 3D printing). Knowledge was operationalised as awareness; no keyed objective knowledge test was administered. Results: The findings show that patients generally accept digital technologies, with perceptions of costs, prior experience of digital dental procedures and educational level having a significant impact. The duration of the patient–clinician relationship, the patient’s dental health, and the history of orthodontic and prosthetic procedures also impacted the acceptance of digital technologies. Notably, clinical staff members were the main source of information, highlighting the importance of professional–patient communication. Conclusions: The results highlight the importance of patient-friendly communication in healthcare and provide a solid basis for the implementation of patient-centred digital dentistry. Future plans should focus on creating specialised educational materials, improving digital literacy, and promoting equal access to cutting-edge technologies in urban and disadvantaged communities. Full article
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25 pages, 1833 KB  
Review
Integration and Innovation in Digital Implantology—Part I: Capabilities and Limitations of Contemporary Workflows: A Narrative Review
by Alexandre Perez and Tommaso Lombardi
Appl. Sci. 2025, 15(22), 12214; https://doi.org/10.3390/app152212214 - 18 Nov 2025
Cited by 1 | Viewed by 1129
Abstract
Advances in digital dental technologies have transformed implant therapy from analog, stepwise processes into advanced, data-driven workflows spanning diagnosis, planning, surgery, and prosthetic delivery. Contemporary digital implantology integrates multiple techniques, tools, and multimodal datasets into comprehensive diagnostic models and treatment workflows, enhancing implant [...] Read more.
Advances in digital dental technologies have transformed implant therapy from analog, stepwise processes into advanced, data-driven workflows spanning diagnosis, planning, surgery, and prosthetic delivery. Contemporary digital implantology integrates multiple techniques, tools, and multimodal datasets into comprehensive diagnostic models and treatment workflows, enhancing implant placement accuracy, procedural efficiency, patient experience, and interdisciplinary coordination. However, integration remains constrained by fragmented datasets, diverse software platforms, and parallel surgical and prosthetic streams. These interfaces often require manual user intervention to convert, process, and align data, thereby increasing the risk of data loss, artifact generation, misalignment, and error accumulation, which may impact implant and prosthetic restorative outcomes. Similarly, implant and prosthetic planning steps continue to rely on subjective, non-standardized user input, requiring advanced experience and training. This narrative review synthesizes current evidence and technical developments in digital implant dentistry based on literature searches in PubMed, Scopus, and Web of Science, with emphasis on publications from 2010 onward, prioritizing systematic reviews, randomized clinical trials, and technical reports focusing on key technological innovations. It presents the current state of the art in digital implantology and identifies major workflow interfaces that constrain seamless, end-to-end integration. This part I summarizes contemporary tools and approaches in digital implant technology. In contrast, Part II of this series will address the emerging roles of artificial intelligence and robotics in overcoming these limitations and advancing toward fully integrated digital implant prosthodontic workflows. Overall, current digital implant workflows are clinically reliable and are equivalent to, or often superior to, conventional approaches in terms of efficiency and accuracy. Nevertheless, their full potential remains limited by persistent software, data, and process interface barriers. Full article
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16 pages, 6484 KB  
Review
Digital Technologies in Implantology: A Narrative Review
by Ani Kafedzhieva, Angelina Vlahova and Bozhana Chuchulska
Bioengineering 2025, 12(9), 927; https://doi.org/10.3390/bioengineering12090927 - 29 Aug 2025
Cited by 3 | Viewed by 3840
Abstract
Digital technologies have significantly advanced implant dentistry, refining diagnosis, treatment planning, surgical precision, and prosthetic rehabilitation. This review explores recent developments, emphasizing accuracy, efficiency, and clinical impact. A literature analysis identifies key innovations, such as digital planning, guided surgery, dynamic navigation, digital impressions [...] Read more.
Digital technologies have significantly advanced implant dentistry, refining diagnosis, treatment planning, surgical precision, and prosthetic rehabilitation. This review explores recent developments, emphasizing accuracy, efficiency, and clinical impact. A literature analysis identifies key innovations, such as digital planning, guided surgery, dynamic navigation, digital impressions and CAD/CAM prosthetics. Digital workflows enhance implant placement by improving precision and reducing deviations compared to freehand techniques. Dynamic navigation provides real-time guidance, offering accuracy comparable to static guides and proving benefits in complex cases. Digital impressions demonstrate high precision, which can match or, in some scenarios, surpass conventional methods, though conventional impressions remain the gold standard for full-arch cases. CAD/CAM technology optimizes prosthetic fit, aesthetics, and material selection. Artificial intelligence and machine learning contribute to treatment planning and predictive analytics, yet challenges persist, including high costs, the need for specialized training, and long-term clinical validation. This review underscores the advantages of digital approaches—improved accuracy, better communication, and minimally invasive procedures—while addressing existing limitations. Emerging technologies, such as AI, augmented reality, and 3D printing, are expected to further transform implantology. Continued research is crucial to fully integrate digital advancements and enhance patient outcomes. Full article
(This article belongs to the Special Issue Dentistry Regenerative Medicine and Oral Bioengineering)
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32 pages, 15103 KB  
Article
3D Printing and Virtual Surgical Planning in Craniofacial and Thoracic Surgery: Applications to Personalised Medicine
by Freddy Patricio Moncayo-Matute, Jhonatan Heriberto Vázquez-Albornoz, Efrén Vázquez-Silva, Ana Julia Hidalgo-Bravo, Paúl Bolívar Torres-Jara and Diana Patricia Moya-Loaiza
J. Pers. Med. 2025, 15(9), 397; https://doi.org/10.3390/jpm15090397 - 25 Aug 2025
Cited by 2 | Viewed by 2259
Abstract
Background/Objectives: The application of additive manufacturing in medicine, and specifically in personalised medicine, has achieved notable development. This article aims to present the results and benefits of applying a comprehensive methodology to simulate, plan, and manufacture customised three-dimensional medical prosthetic devices for use [...] Read more.
Background/Objectives: The application of additive manufacturing in medicine, and specifically in personalised medicine, has achieved notable development. This article aims to present the results and benefits of applying a comprehensive methodology to simulate, plan, and manufacture customised three-dimensional medical prosthetic devices for use in surgery to restore bone structures with congenital and acquired malformations. Methods: To digitally reconstruct a bone structure in three dimensions from a medical image, a segmentation process is developed to correlate the anatomical model. Then, this model is filtered using a post-processing step to generate stereolithography (STL) files, which are rendered using specialised software. The segmentation of tomographic images is achieved by the specific intensity selection, facilitating the analysis of compact and soft tissues within the anatomical region of interest. With the help of a thresholding algorithm, a three-dimensional digital model of the anatomical structure is obtained, ready for printing the required structure. Results: The described cases demonstrate that the use of anatomical test models, cutting guides, and customised prostheses reduces surgical time and hospital stay, and achieves better aesthetic and functional results. Using materials such as polylactic acid (PLA) for presurgical models, appropriate resins for cutting guides, and biocompatible materials such as polyether ether ketone (PEEK) or polymethylmethacrylate (PMMA) for prostheses, the described improvements are achieved. Conclusions: The achievements attained demonstrate the feasibility of applying these techniques, their advantages and their accessibility in Ecuador. They also reinforce the ideas of personalised medicine in the search for medical treatments and procedures tailored to the needs of each patient. Full article
(This article belongs to the Section Personalized Medical Care)
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30 pages, 4515 KB  
Article
Implant-Supported Oral Rehabilitation in Head and Neck Cancer Patients: A 20-Year Single-Center Study (2005–2024)
by Manuel Tousidonis, Santiago Ochandiano, Carlos Navarro-Cuellar, Carlos Navarro-Vila, Javier López de Atalaya, Cristina Maza, Ana María Lopez Lopez, Ignacio Navarro-Cuellar, Alba García Sevilla, Gema Arenas de Frutos, Raul Antunez-Conde, Paloma Planells del Pozo and Jose Ignacio Salmeron
J. Clin. Med. 2025, 14(15), 5435; https://doi.org/10.3390/jcm14155435 - 1 Aug 2025
Cited by 2 | Viewed by 2768
Abstract
Background/Objectives: Oral cancer resection often leads to maxillofacial defects and dentition loss, compromising patients’ quality of life. Implant-supported prosthetic rehabilitation offers a reliable solution to restore function, though factors such as bone reconstruction, radiotherapy, and timing of implant placement (immediate vs. delayed) may [...] Read more.
Background/Objectives: Oral cancer resection often leads to maxillofacial defects and dentition loss, compromising patients’ quality of life. Implant-supported prosthetic rehabilitation offers a reliable solution to restore function, though factors such as bone reconstruction, radiotherapy, and timing of implant placement (immediate vs. delayed) may influence outcomes. This study aimed to evaluate long-term implant survival and rehabilitation timelines in oncologic patients, comparing two cohorts (2005–2014 and 2015–2024) to assess the impact of evolving clinical practices. Methods: A retrospective cohort study was conducted at Hospital General Universitario Gregorio Marañón (Madrid, Spain), including 304 patients who underwent ablative oral cancer surgery and subsequent implant-based rehabilitation between 2005 and 2024. Data on demographics, oncologic treatment, reconstruction, implant timing, and prosthetic rehabilitation were collected. Outcomes were compared using Kaplan–Meier analysis and appropriate statistical tests between the 2005–2014 (n = 122) and 2015–2024 (n = 182) cohorts. Results: A total of 2341 Ticare Implants® were placed, supporting 281 prostheses. Implant placement during primary surgery increased from 41% to 71% (p < 0.001). The median time from surgery to prosthesis significantly decreased from 24 to 15 months (p < 0.001). Five-year implant survival was 95% in the early cohort versus 97% in the later cohort. Implant survival was comparable between irradiated and non-irradiated patients (~94–96%). Fixed prostheses became more frequent (92% vs. 79%, p = 0.002). Conclusions: Implant-supported rehabilitation in oncologic patients is highly feasible and durable, with improved timelines and functional outcomes associated with early implant placement and modern digital planning strategies. Full article
(This article belongs to the Special Issue Research Progress in Osseointegrated Oral Implants)
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19 pages, 3409 KB  
Review
Indications and Complications of Subperiosteal Implants: Literature Review and Case Series
by Gerardo Pellegrino, Maryia Karaban, Carlo Barausse, Amerigo Giudice, Alessandro Antonelli, Roberto Pistilli and Pietro Felice
Dent. J. 2025, 13(8), 337; https://doi.org/10.3390/dj13080337 - 23 Jul 2025
Viewed by 3388
Abstract
Background/Objectives: Severe jawbone atrophy, particularly in elderly or medically compromised patients, presents a significant challenge for conventional implant placement. In cases where bone augmentation is not feasible, alternative techniques—such as short, narrow, tilted, and zygomatic implants—may be indicated for the rehabilitation of the [...] Read more.
Background/Objectives: Severe jawbone atrophy, particularly in elderly or medically compromised patients, presents a significant challenge for conventional implant placement. In cases where bone augmentation is not feasible, alternative techniques—such as short, narrow, tilted, and zygomatic implants—may be indicated for the rehabilitation of the atrophic jaw. Subperiosteal implants have re-emerged as a further viable alternative, especially with recent advancements in digital planning and custom fabrication. This study aims to evaluate the clinical outcomes and complications associated with subperiosteal implants through a literature review and a supporting case series, and to propose clinical preliminary guidelines for their use. Methods: Fourteen studies—including case reports, case series, retrospective studies, and systematic reviews—were analyzed to assess the effectiveness and risk profile of subperiosteal implants. Additionally, we present a case series of nine patients with advanced vertical and horizontal alveolar bone atrophy treated using custom-made, digitally-designed subperiosteal implants. Surgical techniques, prosthetic workflows, and complications were recorded and assessed. Results: Subperiosteal implants were found to be particularly suitable for patients with narrow alveolar crests and severe atrophy where traditional implants are contraindicated. Literature and case series data indicated favorable outcomes, with early complications such as soft tissue inflammation and prosthetic misfit being manageable. A low complication rate was recorded in our series, with digital workflows contributing to improved implant fit and reduced technical errors. Conclusions: Subperiosteal implants could offer an effective solution for complex atrophic cases, provided that patient selection, surgical precision, and prosthetic design are meticulously managed. Based on our findings, clinical recommendations are proposed to guide their application in contemporary practice. Full article
(This article belongs to the Special Issue New Perspectives in Periodontology and Implant Dentistry)
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12 pages, 6846 KB  
Case Report
A Second Chance: Managing Late Implant Failure from Peri-Implantitis with Computer-Guided Bone Regeneration—A Clinical Case Report
by Marco Tallarico, Silvio Mario Meloni, Carlotta Cacciò, Francesco Mattia Ceruso and Aurea Immacolata Lumbau
Reports 2025, 8(3), 118; https://doi.org/10.3390/reports8030118 - 22 Jul 2025
Viewed by 3066
Abstract
Background and Clinical Significance: The retreatment of failed dental implants remains a challenging clinical scenario, particularly when complicated by peri-implantitis and as sociated bone loss. Successful management requires a comprehensive and predictable approach that addresses both hard and soft tissue deficiencies. Case [...] Read more.
Background and Clinical Significance: The retreatment of failed dental implants remains a challenging clinical scenario, particularly when complicated by peri-implantitis and as sociated bone loss. Successful management requires a comprehensive and predictable approach that addresses both hard and soft tissue deficiencies. Case Presentation: This case report illustrates a fully digital, prosthetically driven workflow for the rehabilitation of a posterior mandibular site following implant failure. A 44-year-old female patient underwent removal of a failing implant and adjacent tooth due to advanced peri-implantitis and periodontitis. After healing, a digital workflow—including intraoral scanning, cone-beam computed tomography (CBCT), and virtual planning—was employed to design and fabricate a customized CAD/CAM titanium mesh for vertical guided bone regeneration. The grafting procedure utilized a composite mixture of autogenous bone and anorganic bovine bone (A-Oss). After nine months of healing, two implants with a hydrophilic surface (SOI) were placed using a fully guided surgical protocol (OneGuide system). Subsequent soft tissue grafting and final prosthetic rehabilitation with monolithic zirconia restorations resulted in stable functional and aesthetic outcomes. Conclusions: This case highlights how the integration of modern digital technologies with advanced regenerative procedures and innovative implant surfaces can enhance the predictability and long-term success of implant retreatment in compromised posterior sites. Full article
(This article belongs to the Section Dentistry/Oral Medicine)
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12 pages, 5900 KB  
Technical Note
Digitally-Driven Surgical Guide for Alveoloplasty Prior to Immediate Denture Placement
by Zaid Badr, Jonah Jaworski, Sofia D’Acquisto and Manal Hamdan
Dent. J. 2025, 13(8), 333; https://doi.org/10.3390/dj13080333 - 22 Jul 2025
Viewed by 2201
Abstract
Objective: This article presents a step-by-step digital technique for fabricating a 3D-printed surgical guide to assist in alveoloplasty for immediate denture placement. Methods: The workflow integrates intraoral scanning, virtual tooth extraction, digital soft tissue modeling, and additive manufacturing to produce a customized guide [...] Read more.
Objective: This article presents a step-by-step digital technique for fabricating a 3D-printed surgical guide to assist in alveoloplasty for immediate denture placement. Methods: The workflow integrates intraoral scanning, virtual tooth extraction, digital soft tissue modeling, and additive manufacturing to produce a customized guide with an occlusal window and buccal slot, along with a verification stent. Results: This method ensures precise ridge recontouring and verification, enhancing surgical predictability and prosthetic fit. Conclusions: Unlike traditional surgical guides based on conventional casts or manual fabrication, this fully digital approach offers a practical and replicable protocol that bridges digital planning and clinical execution. By improving surgical precision, reducing operative time, and ensuring optimal denture fit, this technique represents a significant advancement in guided pre-prosthetic surgery. Full article
(This article belongs to the Special Issue New Trends in Digital Dentistry)
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15 pages, 2173 KB  
Review
Optimal Sites for Upper Extremity Amputation: Comparison Between Surgeons and Prosthetists
by Brandon Apagüeño, Sara E. Munkwitz, Nicholas V. Mata, Christopher Alessia, Vasudev Vivekanand Nayak, Paulo G. Coelho and Natalia Fullerton
Bioengineering 2025, 12(7), 765; https://doi.org/10.3390/bioengineering12070765 - 15 Jul 2025
Cited by 2 | Viewed by 2612
Abstract
Upper extremity amputations significantly impact an individual’s physical capabilities, psychosocial well-being, and overall quality of life. The level at which an amputation is performed influences residual limb function, prosthetic compatibility, and long-term patient satisfaction. While surgical guidelines traditionally emphasize maximal limb preservation, prosthetists [...] Read more.
Upper extremity amputations significantly impact an individual’s physical capabilities, psychosocial well-being, and overall quality of life. The level at which an amputation is performed influences residual limb function, prosthetic compatibility, and long-term patient satisfaction. While surgical guidelines traditionally emphasize maximal limb preservation, prosthetists often advocate for amputation sites that optimize prosthetic fit and function, highlighting the need for a collaborative approach. This review examines the discrepancies between surgical and prosthetic recommendations for optimal amputation levels, from digit amputations to shoulder disarticulations, and explores their implications for prosthetic design, functionality, and patient outcomes. Various prosthetic options, including passive functional, body-powered, myoelectric, and hybrid devices, offer distinct advantages and limitations based on the level of amputation. Prosthetists emphasize the importance of residual limb length, not only for mechanical efficiency but also for achieving symmetry with the contralateral limb, minimizing discomfort, and enhancing control. Additionally, emerging technologies such as targeted muscle reinnervation (TMR) and advanced myoelectric prostheses are reshaping rehabilitation strategies, further underscoring the need for precise amputation planning. By integrating insights from both surgical and prosthetic perspectives, this review highlights the necessity of a multidisciplinary approach involving surgeons, prosthetists, rehabilitation specialists, and patients in the decision-making process. A greater emphasis on preoperative planning and interprofessional collaboration can improve prosthetic outcomes, reduce device rejection rates, and ultimately enhance the functional independence and well-being of individuals with upper extremity amputations. Full article
(This article belongs to the Section Biomedical Engineering and Biomaterials)
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13 pages, 8971 KB  
Case Report
The Role of Digital Workflow in Creating a New, Esthetic and Functional Smile in a Periodontally Compromised Patient: A Case Report
by Carlotta Cacciò, Marco Tallarico, Aurea Immacolata Lumbau, Francesco Mattia Ceruso and Milena Pisano
Reports 2025, 8(3), 105; https://doi.org/10.3390/reports8030105 - 8 Jul 2025
Viewed by 1718
Abstract
Background and Clinical Significance: Prosthetic rehabilitation in the aesthetic zone of periodontally compromised patients presents a complex clinical challenge, requiring a careful coordination of aesthetic, functional, and biological demands. This case highlights the benefits of digital dentistry, interdisciplinary collaboration, and regular maintenance in [...] Read more.
Background and Clinical Significance: Prosthetic rehabilitation in the aesthetic zone of periodontally compromised patients presents a complex clinical challenge, requiring a careful coordination of aesthetic, functional, and biological demands. This case highlights the benefits of digital dentistry, interdisciplinary collaboration, and regular maintenance in achieving long-term success in complex rehabilitations of periodontally compromised patients. Case Presentation: This case report describes the digital minimally invasive rehabilitation of a 39-year-old male patient with Stage III periodontitis, occlusal discrepancies, tooth mobility, and an interincisal diastema. A fully digital workflow—including intraoral scanning, aesthetic previewing, and mandibular motion analysis—was employed to guide diagnosis, treatment planning, and prosthetic execution. Conservative tooth preparations using a biologically oriented approach (BOPT) were combined with customised provisional restorations to support soft tissue conditioning and functional control throughout the provisional phases. Mandibular motion tracking facilitated the design of a personalised anterior guidance to improve occlusion and correct the deep bite. The interincisal diastema was initially maintained then closed during the advanced phase of treatment based on aesthetic simulations and patient preference. One unplanned endodontic treatment was required during the provisional phase, but no other complications occurred. Conclusions: At the four-year follow-up, the patient demonstrated stable periodontal and occlusal conditions, improved clinical indices, and high satisfaction with the aesthetic outcome. Full article
(This article belongs to the Section Dentistry/Oral Medicine)
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13 pages, 1674 KB  
Article
Design Process and Early Functional Outcomes of Digitally Planned Immediate Obturator Prostheses After Partial Maxillectomy
by Anh Tuan Ta, Duc Thanh Le, Minh Tuan Dam, Thi Trang Phuong, Duc Minh Nguyen, Hoang Tuan Pham and Minh Son Tong
Prosthesis 2025, 7(4), 80; https://doi.org/10.3390/prosthesis7040080 - 7 Jul 2025
Viewed by 1940
Abstract
Background/Objectives: Partial maxillectomy frequently results in severe impairments of oral functions, such as difficulties in chewing, speech, swallowing, and facial appearance. Immediate prosthetic rehabilitation is challenging because soft tissue healing is typically required before impression taking. This study aimed to (1) develop a [...] Read more.
Background/Objectives: Partial maxillectomy frequently results in severe impairments of oral functions, such as difficulties in chewing, speech, swallowing, and facial appearance. Immediate prosthetic rehabilitation is challenging because soft tissue healing is typically required before impression taking. This study aimed to (1) develop a comprehensive digital workflow for fabricating immediate obturator prostheses using preoperative data and (2) assess their early clinical effectiveness in restoring oral functions after surgery. Methods: In this prospective clinical study, 20 patients undergoing partial maxillectomy from January 2023 to January 2025 were enrolled. A digital workflow combining cone-beam computed tomography (CBCT), intraoral scanning, CAD/CAM design, and 3D metal printing was implemented. Obturator prostheses were digitally designed preoperatively and inserted immediately post-resection. Functional outcomes were postoperatively evaluated after one month using the Obturator Functioning Scale (OFS), which measures functional, speech, esthetic, and psychosocial aspects. Results: The digitally fabricated immediate obturator prostheses were successfully placed intraoperatively in all patients. Most participants reported mild to moderate difficulties, with speech-related issues being the most common, while esthetic concerns were minimal. Masticatory function was satisfactorily restored in 75% of cases, and 60% of patients experienced minimal fluid leakage during swallowing. No significant differences were found between genders. Patients with larger defects tended to report greater functional challenges. Conclusions: The digitally planned immediate obturator prosthesis provides a practical and effective solution for early rehabilitation following partial maxillectomy. This digital workflow reduces patient discomfort, restores key oral functions, and facilitates psychosocial recovery. Full article
(This article belongs to the Special Issue Prosthetic Rehabilitation in Oral Cancer Patients)
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15 pages, 2435 KB  
Case Report
The First Biological Respect Protocol: A Biodigital Technique for Definitive Customized One-Time Abutments—A Case Report
by Franco Rizzuto and Silvia Rizzuto
J. Clin. Med. 2025, 14(13), 4448; https://doi.org/10.3390/jcm14134448 - 23 Jun 2025
Viewed by 748
Abstract
Background/Objectives: Dental implants represent a viable solution for replacing missing teeth; however, multiple disconnections and reconnections of intermediate abutments contribute to the apical displacement of the peri-implant connective tissue barrier, resulting in additional marginal bone loss. To the best of our knowledge, no [...] Read more.
Background/Objectives: Dental implants represent a viable solution for replacing missing teeth; however, multiple disconnections and reconnections of intermediate abutments contribute to the apical displacement of the peri-implant connective tissue barrier, resulting in additional marginal bone loss. To the best of our knowledge, no definitive customized abutments currently exist that are specifically designed according to the morphology of the tooth to be replaced and its position within the dental arch, allowing for digital planning within the prosthetic implant design and insertion during the surgical procedure without subsequent disconnection. Methods: The First Biological Respect (FR) technique, described in this case report, enables the digital planning not only of the implant but also of the patented FR customized-shaped, definitive abutment and associated FR prosthetic components. The FR technique was applied to a case involving an immediate post-extraction implant in position 12. Results: With the limitations of a case report, the application of the FR protocol demonstrated stable crestal bone levels at the 1-year follow-up. Additionally, soft tissue volume was maintained at 6 months, reflecting the accuracy of the customized prosthetic components in supporting, guiding, and protecting peri-implant soft tissues. At the 1-year follow-up, an increase in soft tissue volume was observed, likely attributable to tissue maturation and the further customization of the definitive prosthetic elements. Conclusions: The FR technique represents a viable therapeutic alternative that, through its patented, fully customized components, allows for the digital planning of the implant, as well as the customized definitive abutment, coping, provisional, and final prosthetic framework. This facilitates a single-stage surgical and prosthetic approach. By eliminating the need for repeated abutment disconnections, this method supports the long-term stability of both hard and soft peri-implant tissues while also reducing overall treatment time for both clinician and patient. Further studies involving larger patient cohorts are necessary to validate this protocol. Full article
(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
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13 pages, 9365 KB  
Article
A Quality Study on Patients’ Perceptions After Digitally Driven Smile Creation Including Aligners and Minimally Invasive Prosthetic Restorations
by Marco Tallarico, Aurea Immacolata Lumbau, Mariapia Sorrenti, Roberta Lione, Carlotta Cacciò, Marco Annucci, Silvio Mario Meloni and Milena Pisano
Prosthesis 2025, 7(4), 68; https://doi.org/10.3390/prosthesis7040068 - 21 Jun 2025
Cited by 1 | Viewed by 1641
Abstract
Background: Aesthetic dentistry increasingly demands minimally invasive, predictable, and patient-centered solutions. Digital technologies and AI-driven planning tools are now integral to interdisciplinary treatments. Aim: To evaluate, by means of a 16-item questionnaire, patients’ perceptions of smile aesthetics and oral function before and after [...] Read more.
Background: Aesthetic dentistry increasingly demands minimally invasive, predictable, and patient-centered solutions. Digital technologies and AI-driven planning tools are now integral to interdisciplinary treatments. Aim: To evaluate, by means of a 16-item questionnaire, patients’ perceptions of smile aesthetics and oral function before and after receiving clear aligner therapy followed by minimally invasive ceramic veneers, using digital planning and Smile Creator software. Materials and Methods: Five adult patients underwent digital smile design, clear aligner therapy, and feldspathic veneer placement. Pre- and post-treatment perceptions of smile aesthetics and function were assessed using a structured questionnaire. AI-based simulation tools (2D and 4 K TruSmile video previews) were incorporated. Paired t-tests were used to compare outcomes before and after treatment. Results: Mean pre-treatment scores were 4.8 for smile aesthetics and 6.6 for function. Post-treatment scores significantly improved to 9.8 (p = 0.001) and 9.4 (p = 0.002), respectively. Patients rated AI-generated smile previews more favorably than 2D designs and acknowledged the value of digital tools in understanding and accepting treatment. Conclusions: The integration of digital and AI-based tools in aesthetic dentistry enhances patient communication, improves predictability, and enables minimally invasive treatment. Patient satisfaction was high, underscoring the effectiveness of the combined orthodontic and prosthetic approach. Full article
(This article belongs to the Section Prosthodontics)
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