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11 pages, 251 KiB  
Article
Implementation of the Memory Support System for Individuals with Mild Cognitive Impairment: A Feasibility Survey Study
by Suraj Brar, Mirou Jaana, Octavio A. Santos, Nicholas Kassabri, Lisa Sweet, Frank Knoefel, Melanie Chandler, Atul Jaiswal and Neil W. Thomas
J. Dement. Alzheimer's Dis. 2025, 2(3), 26; https://doi.org/10.3390/jdad2030026 (registering DOI) - 7 Aug 2025
Abstract
Background/Objectives: Mild Cognitive Impairment (MCI), a condition between normal aging and dementia, is characterized by cognitive changes that do not significantly affect instrumental activities of daily living. The Memory Support System (MSS), an evidence-based behavioral intervention developed by the Mayo Clinic, has been [...] Read more.
Background/Objectives: Mild Cognitive Impairment (MCI), a condition between normal aging and dementia, is characterized by cognitive changes that do not significantly affect instrumental activities of daily living. The Memory Support System (MSS), an evidence-based behavioral intervention developed by the Mayo Clinic, has been shown to aid those living with MCI and their support partners in coping with cognitive challenges. However, the MSS has not been offered clinically within the Canadian context. Therefore, we conducted a study assessing the feasibility of the MSS from the perspectives of individuals living with MCI and their support partners. Methods: Participants from an institutional registry of research participants, patients, and support partners at a memory clinic, as well as members of a local Dementia Society, were approached to complete an online or paper version of a survey assessing feasibility dimensions. Responses were compared between and within groups for differences in mean scores and associations between linked binary choice response questions. Results: A total of 77 responses were received; 39 surveys were completed by participants with MCI, and 38 by support partners. Respondents found the MSS to be acceptable and practical. On average, participants thought it would be more difficult to train in using the MSS than support partners. Both groups expressed interest in the intervention. On average, participants with MCI and support partners preferred virtual MSS training to in-person and indicated more interest in participating in training over six weeks as compared to two weeks. Conclusions: Flexibility in duration and format when offering the MSS are important considerations when offering the intervention as part of a clinical program. Future research should evaluate cost-effectiveness (e.g., financial, staff resources, etc.) of the MSS approach if it were to be institutionalized in the Ontario healthcare system. Full article
32 pages, 1885 KiB  
Article
Mapping Linear and Configurational Dynamics to Fake News Sharing Behaviors in a Developing Economy
by Claudel Mombeuil, Hugues Séraphin and Hemantha Premakumara Diunugala
Technologies 2025, 13(8), 341; https://doi.org/10.3390/technologies13080341 - 6 Aug 2025
Abstract
The proliferation of social media has paradoxically facilitated the widespread dissemination of fake news, impacting individuals, politics, economics, and society as a whole. Despite the increasing scholarly research on this phenomenon, a significant gap exists regarding its dynamics in developing countries, particularly how [...] Read more.
The proliferation of social media has paradoxically facilitated the widespread dissemination of fake news, impacting individuals, politics, economics, and society as a whole. Despite the increasing scholarly research on this phenomenon, a significant gap exists regarding its dynamics in developing countries, particularly how predictors of fake news sharing interact, rather than merely their net effects. To acquire a more nuanced understanding of fake news sharing behavior, we propose identifying the direct and complex interplay among key variables by utilizing a dual analytical framework, leveraging Structural Equation Modeling (SEM) for linear relationships and Fuzzy-Set Qualitative Comparative Analysis (fsQCA) to uncover asymmetric patterns. Specifically, we investigate the influence of news-find-me orientation, social media trust, information-sharing tendencies, and status-seeking motivation on the propensity of fake news sharing behavior. Additionally, we delve into the moderating influence of social media literacy on these observed effects. Based on a cross-sectional survey of 1028 Haitian social media users, the SEM analysis revealed that news-find-me perception had a negative but statistically insignificant influence on fake news sharing behavior. In contrast, information sharing exhibited a significant negative association. Trust in social media was positively and significantly linked to fake news sharing behavior. Meanwhile, status-seeking motivation was positively associated with fake news sharing behavior, although the association did not reach statistical significance. Crucially, social media literacy moderated the effects of trust and information sharing. Interestingly, fsQCA identified three core configurations for fake news sharing: (1) low status seeking, (2) low information-sharing tendencies, and (3) a unique interaction of low “news-find-me” orientation and high social media trust. Furthermore, low social media literacy emerged as a direct core configuration. These findings support the urgent need to prioritize social media literacy as a key intervention in combating the dissemination of fake news. Full article
(This article belongs to the Section Information and Communication Technologies)
14 pages, 614 KiB  
Article
Development of Cut Scores for Feigning Spectrum Behavior on the Orebro Musculoskeletal Pain Screening Questionnaire and the Perceived Stress Scale: A Simulation Study
by John Edward McMahon, Ashley Craig and Ian Douglas Cameron
J. Clin. Med. 2025, 14(15), 5504; https://doi.org/10.3390/jcm14155504 - 5 Aug 2025
Abstract
Background/Objectives: Feigning spectrum behavior (FSB) is the exaggeration, fabrication, or false imputation of symptoms. It occurs in compensable injury with great cost to society by way of loss of productivity and excessive costs. The aim of this study is to identify feigning [...] Read more.
Background/Objectives: Feigning spectrum behavior (FSB) is the exaggeration, fabrication, or false imputation of symptoms. It occurs in compensable injury with great cost to society by way of loss of productivity and excessive costs. The aim of this study is to identify feigning by developing cut scores on the long and short forms (SF) of the Orebro Musculoskeletal Pain Screening Questionnaire (OMPSQ and OMPSQ-SF) and the Perceived Stress Scale (PSS and PSS-4). Methods: As part of pre-screening for a support program, 40 injured workers who had been certified unfit for work for more than 2 weeks were screened once with the OMPSQ and PSS by telephone by a mental health professional. A control sample comprised of 40 non-injured community members were screened by a mental health professional on four occasions under different aliases, twice responding genuinely and twice simulating an injury. Results: Differences between the workplace injured people and the community sample were compared using ANCOVA with age and gender as covariates, and then receiver operator characteristics (ROCs) were calculated. The OMPSQ and OMPSQ-SF discriminated (ρ < 0.001) between all conditions. All measures discriminated between the simulation condition and workplace injured people (ρ < 0.001). Intraclass correlation demonstrated the PSS, PSS-4, OMPSQ, and OMPSQ-SF were reliable (ρ < 0.001). Area Under the Curve (AUC) was 0.750 for OMPSQ and 0.835 for OMPSQ-SF for work-injured versus simulators. Conclusions: The measures discriminated between injured and non-injured people and non-injured people instructed to simulate injury. Non-injured simulators produced similar scores when they had multiple exposures to the test materials, showing the uniformity of feigning spectrum behavior on these measures. The OMPSQ-SF has adequate discriminant validity and sensitivity to feigning spectrum behavior, making it optimal for telephone screening in clinical practice. Full article
(This article belongs to the Section Clinical Rehabilitation)
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36 pages, 1202 KiB  
Article
Exploring Service Needs and Development Strategies for the Healthcare Tourism Industry Through the APA-NRM Technique
by Chung-Ling Kuo and Chia-Li Lin
Sustainability 2025, 17(15), 7068; https://doi.org/10.3390/su17157068 - 4 Aug 2025
Abstract
With the arrival of an aging society and the continuous extension of the human lifespan, the quality of life has not improved in a corresponding manner. People’s demand for happiness and health is increasing. As a result, a model emerged that integrates tourism [...] Read more.
With the arrival of an aging society and the continuous extension of the human lifespan, the quality of life has not improved in a corresponding manner. People’s demand for happiness and health is increasing. As a result, a model emerged that integrates tourism and medical services, which is health tourism. This growing demand has prompted many service providers to see it as a business opportunity and enter the market. Tourism can help travelers release work stress and restore physical and mental balance; meanwhile, health check-ups and disease treatment can help them regain health. Consumers have long favored health and medical tourism because it helps relieve stress and promotes overall well-being. As people age, some consumers experience a gradual decline in physical functions, making it difficult for them to participate in regular travel services provided by traditional travel agencies. Therefore, this study aims to explore the service needs of health and medical tourism customers (tourists/patients) and the interrelationships among these service needs, so that health and medical tourism service providers can develop more customized and diversified services. This study identifies four key drivers of medical tourism services: medical services, medical facilities, tour planning, and hospitality facilities. This study uses the APA (attention and performance analysis) method to assess each dimension and criterion and utilizes the DEMATEL method with the NRM (network relationship map) to identify network relationships. By combining APA and NRM techniques, this study develops the APA-NRM technique to evaluate adoption strategies and identify suitable paths for health tourism services, providing tailored development strategies and recommendations for service providers to enhance the service experience. Full article
(This article belongs to the Special Issue Inclusive Tourism and Its Place in Sustainable Development Concepts)
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3 pages, 150 KiB  
Editorial
Editorial for the Special Issue “Virtual Reality and Metaverse: Impact on the Digital Transformation of Society—2nd Edition”
by Diego Vergara
Future Internet 2025, 17(8), 354; https://doi.org/10.3390/fi17080354 - 4 Aug 2025
Viewed by 26
Abstract
Virtual reality (VR) is transforming society by enabling the development of diverse applications across a wide range of fields [...] Full article
27 pages, 5026 KiB  
Review
China’s Carbon Emissions Trading Market: Current Situation, Impact Assessment, Challenges, and Suggestions
by Qidi Wang, Jinyan Zhan, Hailin Zhang, Yuhan Cao, Zheng Yang, Quanlong Wu and Ali Raza Otho
Land 2025, 14(8), 1582; https://doi.org/10.3390/land14081582 - 3 Aug 2025
Viewed by 126
Abstract
As the world’s largest developing and carbon-emitting country, China is accelerating its greenhouse gas (GHG) emission reduction process, and it is of vital importance in achieving the goals set out in the Paris Agreement. This paper examines the historical development and current operation [...] Read more.
As the world’s largest developing and carbon-emitting country, China is accelerating its greenhouse gas (GHG) emission reduction process, and it is of vital importance in achieving the goals set out in the Paris Agreement. This paper examines the historical development and current operation of China’s carbon emissions trading market (CETM). The current progress of research on the implementation of carbon emissions trading policy (CETP) is described in four dimensions: environment, economy, innovation, and society. The results show that CETP generates clear environmental and social benefits but exhibits mixed economic and innovation effects. Furthermore, this paper analyses the challenges of China’s carbon market, including the green paradox, the low carbon price, the imperfections in cap setting and allocation of allowances, the small scope of coverage, and the weakness of the legal supervision system. Ultimately, this paper proposes recommendations for fostering China’s CETM with the anticipation of offering a comprehensive outlook for future research. Full article
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17 pages, 524 KiB  
Article
Collaborative Practices in Mental Health Care: A Concept Analysis
by Eslia Pinheiro, Carlos Laranjeira, Camila Harmuch, José Mateus Bezerra Graça, Amira Mohammed Ali, Feten Fekih-Romdhane, Murat Yıldırım, Ana Kalliny Severo and Elisângela Franco
Healthcare 2025, 13(15), 1891; https://doi.org/10.3390/healthcare13151891 - 2 Aug 2025
Viewed by 109
Abstract
Background/Objectives: Collaboration in mental health care is essential for implementing a model oriented towards the psychosocial rehabilitation of people based on multifaceted interventions involving different actors and sectors of society to respond to demands. Despite the benefits presented by the scientific evidence, there [...] Read more.
Background/Objectives: Collaboration in mental health care is essential for implementing a model oriented towards the psychosocial rehabilitation of people based on multifaceted interventions involving different actors and sectors of society to respond to demands. Despite the benefits presented by the scientific evidence, there are still many barriers to collaborative care, and professionals continue to struggle in reorienting their conduct. The current situation demands organization and the framing of well-founded action plans to overcome challenges, which in turn requires a detailed understanding of collaborative practices in mental health care and their conceptual boundaries. A concept analysis was undertaken to propose a working definition of collaborative practices in mental health care (CPMHC). Methods: This paper used the Walker and Avant concept analysis method. This includes identifying the defining concept attributes, antecedents, consequences, and empirical referents. A literature search was carried out from November 2024 to February 2025 in three databases (Medline, CINAHL, and LILACS), considering studies published between 2010 and 2024. Results: The final sample of literature investigated consisted of 30 studies. The key attributes were effective communication, building bonds, co-responsibility for care, hierarchical flexibility, articulation between services, providers and community, monitoring and evaluating of care processes, and attention to the plurality of sociocultural contexts. Conclusions: This comprehensive analysis contributes to guiding future research and policy development of collaborative practices in mental health, considering the individual, relational, institutional, and social levels. Further research is possible to deepen the understanding of the production of collaborative practices in mental health in the face of the complexity of social relations and structural inequities. Full article
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26 pages, 1514 KiB  
Article
Measuring the Digital Economy in Kazakhstan: From Global Indices to a Contextual Composite Index (IDED)
by Oxana Denissova, Zhadyra Konurbayeva, Monika Kulisz, Madina Yussubaliyeva and Saltanat Suieubayeva
Economies 2025, 13(8), 225; https://doi.org/10.3390/economies13080225 - 2 Aug 2025
Viewed by 171
Abstract
This study examines the development of the digital economy and society in the Republic of Kazakhstan by combining international benchmarking with a context-specific national framework. It highlights the limitations of existing global indices such as DESI, NRI, and EGDI in capturing the structural [...] Read more.
This study examines the development of the digital economy and society in the Republic of Kazakhstan by combining international benchmarking with a context-specific national framework. It highlights the limitations of existing global indices such as DESI, NRI, and EGDI in capturing the structural and institutional dimensions of digital transformation in emerging economies. To address this gap, the study introduces a novel composite metric, the Index of Digital Economy Development (IDED), which integrates five sub-indices: infrastructure, usage, human capital, economic digitization, and transformation effectiveness. The methodology involves comparative index analysis, the construction of the IDED, and statistical validation through a public opinion survey and regression modeling. Key findings indicate that cybersecurity is a critical yet under-represented component of digital development, showing strong empirical correlations with DESI scores in benchmark countries. The results also highlight Kazakhstan’s strengths in digital public services and internet access, contrasted with weaknesses in business digitization and innovation. The proposed IDED offers a more comprehensive and policy-relevant tool for assessing digital progress in transitional economies. This study contributes to the literature by proposing a replicable index structure and providing empirical evidence for the inclusion of cybersecurity in national digital economy assessments. The aim of the study is to assess Kazakhstan’s digital economy development by addressing limitations in global measurement frameworks. Methodologically, it combines comparative index analysis, the construction of a national composite index (IDED), and statistical validation using a regional survey and regression analysis. The findings reveal both strengths and gaps in Kazakhstan’s digital landscape, particularly in cybersecurity and SME digitalization. The IDED introduces an innovative, context-sensitive framework that enhances the measurement of digital transformation in transitional economies. Full article
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19 pages, 5488 KiB  
Article
Treatment of Recycled Metallurgical By-Products for the Recovery of Fe and Zn Through a Plasma Reactor and RecoDust
by Wolfgang Reiter, Loredana Di Sante, Vincenzo Pepe, Marta Guzzon and Klaus Doschek-Held
Metals 2025, 15(8), 867; https://doi.org/10.3390/met15080867 (registering DOI) - 1 Aug 2025
Viewed by 130
Abstract
The 1.9 billion metric tons of steel globally manufactured in 2023 justify the steel industry’s pivotal role in modern society’s growth. Considering the rapid development of countries that have not fully taken part in the global market, such as Africa, steel production is [...] Read more.
The 1.9 billion metric tons of steel globally manufactured in 2023 justify the steel industry’s pivotal role in modern society’s growth. Considering the rapid development of countries that have not fully taken part in the global market, such as Africa, steel production is expected to increase in the next decade. However, the environmental burden associated with steel manufacturing must be mitigated to achieve sustainable production, which would align with the European Green Deal pathway. Such a burden is associated both with the GHG emissions and with the solid residues arising from steel manufacturing, considering both the integrated and electrical routes. The valorisation of the main steel residues from the electrical steelmaking is the central theme of this work, referring to the steel electric manufacturing in the Dalmine case study. The investigation was carried out from two different points of view, comprising the action of a plasma electric reactor and a RecoDust unit to optimize the recovery of iron and zinc, respectively, being the two main technologies envisioned in the EU-funded research project ReMFra. This work focuses on those preliminary steps required to detect the optimal recipes to consider for such industrial units, such as thermodynamic modelling, testing the mechanical properties of the briquettes produced, and the smelting trials carried out at pilot scale. However, tests for the usability of the dusty feedstock for RecoDust are carried out, and, with the results, some recommendations for pretreatment can be made. The outcomes show the high potential of these streams for metal and mineral recovery. Full article
20 pages, 7986 KiB  
Article
Investigating the Gender-Climate Nexus: Strengthening Women’s Roles in Adaptation and Mitigation in the Sidi Bouzid Region
by Houda Mazhoud, Arij Boucif, Abir Ouhibi, Lobna Hajji-Hedfi and Fraj Chemak
Climate 2025, 13(8), 164; https://doi.org/10.3390/cli13080164 - 1 Aug 2025
Viewed by 226
Abstract
Tunisia faces significant challenges related to climate change, which deeply affect its natural and agricultural resources. This reality threatens not only food security but also the economic stability of rural communities and mainly rural women. This research aims to assess the impact of [...] Read more.
Tunisia faces significant challenges related to climate change, which deeply affect its natural and agricultural resources. This reality threatens not only food security but also the economic stability of rural communities and mainly rural women. This research aims to assess the impact of climate change on rural women in the agricultural development group in Sidi Bouzid, focusing on the strategies adopted and the support provided by various stakeholders to mitigate this impact. To achieve this, we developed a rigorous methodology that includes structured questionnaires, focus group discussions, and topological analysis through Multiple Correspondence Analysis (MCA). The results revealed that rural women were categorized into three groups based on their vulnerability to climate change: severely vulnerable, vulnerable, and adaptive. The findings highlighted the significant impact of climate change on water resources, which has increased family tensions and reduced agricultural incomes, making daily life more challenging for rural women. Furthermore, a deeper analysis of interactions with external stakeholders emphasized the important role of civil society, public organizations, and research institutions in strengthening the climate resilience of rural women. Given these findings, strategic recommendations aim to enhance stakeholder coordination, expand partnerships, and improve access to essential technologies and resources for women in agricultural development groups. Full article
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18 pages, 6642 KiB  
Article
Flood Impact and Evacuation Behavior in Toyohashi City, Japan: A Case Study of the 2 June 2023 Heavy Rain Event
by Masaya Toyoda, Reo Minami, Ryoto Asakura and Shigeru Kato
Sustainability 2025, 17(15), 6999; https://doi.org/10.3390/su17156999 - 1 Aug 2025
Viewed by 185
Abstract
Recent years have seen frequent heavy rainfall events in Japan, often linked to Baiu fronts and typhoons. These events are exacerbated by global warming, leading to an increased frequency and intensity. As floods represent a serious threat to sustainable urban development and community [...] Read more.
Recent years have seen frequent heavy rainfall events in Japan, often linked to Baiu fronts and typhoons. These events are exacerbated by global warming, leading to an increased frequency and intensity. As floods represent a serious threat to sustainable urban development and community resilience, this study contributes to sustainability-focused risk reduction through integrated analysis. This study focuses on the 2 June 2023 heavy rain disaster in Toyohashi City, Japan, which caused extensive damage due to flooding from the Yagyu and Umeda Rivers. Using numerical models, this study accurately reproduces flooding patterns, revealing that high tides amplified the inundation area by 1.5 times at the Yagyu River. A resident questionnaire conducted in collaboration with Toyohashi City identifies key trends in evacuation behavior and disaster information usage. Traditional media such as TV remain dominant, but younger generations leverage electronic devices for disaster updates. These insights emphasize the need for targeted information dissemination and enhanced disaster preparedness strategies, including online materials and flexible training programs. The methods and findings presented in this study can inform local and regional governments in building adaptive disaster management policies, which contribute to a more sustainable society. Full article
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14 pages, 1502 KiB  
Review
A Bibliographic Analysis of Multi-Risk Assessment Methodologies for Natural Disaster Prevention
by Gilles Grandjean
GeoHazards 2025, 6(3), 41; https://doi.org/10.3390/geohazards6030041 - 1 Aug 2025
Viewed by 171
Abstract
In light of the increasing frequency and intensity of natural phenomena, whether climatic or telluric, the relevance of multi-risk assessment approaches has become an important issue for understanding and estimating the impacts of disasters on complex socioeconomic systems. Two aspects contribute to the [...] Read more.
In light of the increasing frequency and intensity of natural phenomena, whether climatic or telluric, the relevance of multi-risk assessment approaches has become an important issue for understanding and estimating the impacts of disasters on complex socioeconomic systems. Two aspects contribute to the worsening of this situation. First, climate change has heightened the incidence and, in conjunction, the seriousness of geohazards that often occur with each other. Second, the complexity of these impacts on societies is drastically exacerbated by the interconnections between urban areas, industrial sites, power or water networks, and vulnerable ecosystems. In front of the recent research on this problem, and the necessity to figure out the best scientific positioning to address it, we propose, through this review analysis, to revisit existing literature on multi-risk assessment methodologies. By this means, we emphasize the new recent research frameworks able to produce determinant advances. Our selection corpus identifies pertinent scientific publications from various sources, including personal bibliographic databases, but also OpenAlex outputs and Web of Science contents. We evaluated these works from different criteria and key findings, using indicators inspired by the PRISMA bibliometric method. Through this comprehensive analysis of recent advances in multi-risk assessment approaches, we highlight main issues that the scientific community should address in the coming years, we identify the different kinds of geohazards concerned, the way to integrate them in a multi-risk approach, and the characteristics of the presented case studies. The results underscore the urgency of developing robust, adaptable methodologies, effectively able to capture the complexities of multi-risk scenarios. This challenge should be at the basis of the keys and solutions contributing to more resilient socioeconomic systems. Full article
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32 pages, 444 KiB  
Article
Does Digital Literacy Increase Farmers’ Willingness to Adopt Livestock Manure Resource Utilization Modes: An Empirical Study from China
by Xuefeng Ma, Yahui Li, Minjuan Zhao and Wenxin Liu
Agriculture 2025, 15(15), 1661; https://doi.org/10.3390/agriculture15151661 - 1 Aug 2025
Viewed by 232
Abstract
Enhancing farmers’ digital literacy is both an inevitable requirement for adapting to the digital age and an important measure for promoting the sustainable development of livestock and poultry manure resource utilization. This study surveyed and obtained data from 1047 farm households in Ningxia [...] Read more.
Enhancing farmers’ digital literacy is both an inevitable requirement for adapting to the digital age and an important measure for promoting the sustainable development of livestock and poultry manure resource utilization. This study surveyed and obtained data from 1047 farm households in Ningxia and Gansu, two provinces in China that have long implemented livestock manure resource utilization policies, from December 2023 to January 2024, and employed the binary probit model to analyze how digital literacy influences farmers’ willingness to adopt two livestock manure resource utilization modes, as well as to analyze the moderating role of three policy regulations. This paper also explores the heterogeneous results in different village forms and income groups. The results are as follows: (1) Digital literacy significantly and positively impacts farmers’ willingness to adopt both the “household collection” mode and the “livestock community” mode. For every one-unit increase in a farmer’s digital literacy, the probability of farmers’ willingness to adopt the “household collection” mode rises by 22 percentage points, and the probability of farmers’ willingness to adopt the “livestock community” mode rises by 19.8 percentage points. After endogeneity tests and robustness checks, the conclusion still holds. (2) Mechanism analysis results indicate that guiding policy and incentive policy have a positive moderation effect on the link between digital literacy and the willingness to adopt the “household collection” mode. Meanwhile, incentive policy also positively moderates the relationship between digital literacy and the willingness to adopt the “livestock community” mode. (3) Heterogeneity analysis results show that the positive effect of digital literacy on farmers’ willingness to adopt two livestock manure resource utilization modes is stronger in “tight-knit society” rural areas and in low-income households. (4) In further discussion, we find that digital literacy removes the information barriers for farmers, facilitating the conversion of willingness into behavior. The value of this study is as follows: this paper provides new insights for the promotion of livestock and poultry manure resource utilization policies in countries and regions similar to the development process of northwest China. Therefore, enhancing farmers’ digital literacy in a targeted way, strengthening the promotion of grassroots policies on livestock manure resource utilization, formulating diversified ecological compensation schemes, and establishing limited supervision and penalty rules can boost farmers’ willingness to adopt manure resource utilization models. Full article
(This article belongs to the Special Issue Application of Biomass in Agricultural Circular Economy)
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11 pages, 1219 KiB  
Article
The Church and Academia Model: New Paradigm for Spirituality and Mental Health Research
by Marta Illueca, Samantha M. Meints, Megan M. Miller, Dikachi Osaji and Benjamin R. Doolittle
Religions 2025, 16(8), 998; https://doi.org/10.3390/rel16080998 (registering DOI) - 31 Jul 2025
Viewed by 208
Abstract
Ongoing interest in the intersection of spirituality and health has prompted a need for integrated research. This report proposes a distinct approach in a model that allows for successful and harmonious cross-fertilization within these latter two areas of interest. Our work is especially [...] Read more.
Ongoing interest in the intersection of spirituality and health has prompted a need for integrated research. This report proposes a distinct approach in a model that allows for successful and harmonious cross-fertilization within these latter two areas of interest. Our work is especially pertinent to inquiries around the role of spirituality in mental health, with special attention to chronic pain conditions. The latter have become an open channel for novel avenues to explore the field of spirituality-based interventions within the arena of psychological inquiry. To address this, the authors developed and implemented the Church and Academia Model, a prototype for an innovative collaborative research project, with the aim of exploring the role of devotional practices, and their potential to be used as therapeutic co-adjuvants or tools to enhance the coping skills of patients with chronic pain. Keeping in mind that the church presents a rich landscape for clinical inquiry with broad relevance for clinicians and society at large, we created a unique hybrid research model. This is a new paradigm that focuses on distinct and well-defined studies where the funding, protocol writing, study design, and implementation are shared by experts from both the pastoral and clinical spaces. A team of theologians, researchers, and healthcare providers, including clinical pain psychologists, built a coalition leveraging their respective skill sets. Each expert is housed in their own environs, creating a functional network that has proven academically productive and pastorally effective. Key outputs include the creation and validation of a new psychometric measure, the Pain-related PRAYER Scale (PPRAYERS), an associated bedside prayer tool and a full-scale dissemination strategy through journal publications and specialty society conferences. This collaborative prototype is also an ideal fit for integrated knowledge translation platforms, and it is a promising paradigm for future collaborative projects focused on spirituality and mental health. Full article
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24 pages, 2310 KiB  
Review
Exploring the Use of Viral Vectors Pseudotyped with Viral Glycoproteins as Tools to Study Antibody-Mediated Neutralizing Activity
by Miguel Ramos-Cela, Vittoria Forconi, Roberta Antonelli, Alessandro Manenti and Emanuele Montomoli
Microorganisms 2025, 13(8), 1785; https://doi.org/10.3390/microorganisms13081785 - 31 Jul 2025
Viewed by 260
Abstract
Recent outbreaks of highly pathogenic human RNA viruses from probable zoonotic origin have highlighted the relevance of epidemic preparedness as a society. However, research in vaccinology and virology, as well as epidemiologic surveillance, is often constrained by the biological risk that live virus [...] Read more.
Recent outbreaks of highly pathogenic human RNA viruses from probable zoonotic origin have highlighted the relevance of epidemic preparedness as a society. However, research in vaccinology and virology, as well as epidemiologic surveillance, is often constrained by the biological risk that live virus experimentation entails. These also involve expensive costs, time-consuming procedures, and advanced personnel expertise, hampering market access for many drugs. Most of these drawbacks can be circumvented with the use of pseudotyped viruses, which are surrogate, non-pathogenic recombinant viral particles bearing the surface envelope protein of a virus of interest. Pseudotyped viruses significantly expand the research potential in virology, enabling the study of non-culturable or highly infectious pathogens in a safer environment. Most are derived from lentiviral vectors, which confer a series of advantages due to their superior efficiency. During the past decade, many studies employing pseudotyped viruses have evaluated the efficacy of vaccines or monoclonal antibodies for relevant pathogens such as HIV-1, Ebolavirus, Influenza virus, or SARS-CoV-2. In this review, we aim to provide an overview of the applications of pseudotyped viruses when evaluating the neutralization capacity of exposed individuals, or candidate vaccines and antivirals in both preclinical models and clinical trials, to further help develop effective countermeasures against emerging neutralization-escape phenotypes. Full article
(This article belongs to the Section Virology)
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