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25 pages, 2379 KiB  
Article
A Semi-Automated, Hybrid GIS-AI Approach to Seabed Boulder Detection Using High Resolution Multibeam Echosounder
by Eoin Downing, Luke O’Reilly, Jan Majcher, Evan O’Mahony and Jared Peters
Remote Sens. 2025, 17(15), 2711; https://doi.org/10.3390/rs17152711 - 5 Aug 2025
Abstract
The detection of seabed boulders is a critical step in mitigating geological hazards during the planning and construction of offshore wind energy infrastructure, as well as in supporting benthic ecological and palaeoglaciological studies. Traditionally, side-scan sonar (SSS) has been favoured for such detection, [...] Read more.
The detection of seabed boulders is a critical step in mitigating geological hazards during the planning and construction of offshore wind energy infrastructure, as well as in supporting benthic ecological and palaeoglaciological studies. Traditionally, side-scan sonar (SSS) has been favoured for such detection, but the growing availability of high-resolution multibeam echosounder (MBES) data offers a cost-effective alternative. This study presents a semi-automated, hybrid GIS-AI approach that combines bathymetric position index filtering and a Random Forest classifier to detect boulders and delineate boulder fields from MBES data. The method was tested on a 0.24 km2 site in Long Island Sound using 0.5 m resolution data, achieving 83% recall, 73% precision, and an F1-score of 77—slightly outperforming the average of expert manual picks while offering a substantial improvement in time-efficiency. The workflow was validated against a consensus-based master dataset and applied across a 79 km2 study area, identifying over 75,000 contacts and delineating 89 contact clusters. The method enables objective, reproducible, and scalable boulder detection using only MBES data. Its ability to reduce reliance on SSS surveys while maintaining high accuracy and offering workflow customization makes it valuable for geohazard assessment, benthic habitat mapping, and offshore infrastructure planning. Full article
(This article belongs to the Section Ocean Remote Sensing)
20 pages, 2243 KiB  
Article
Increasing Access and Availability of Nutrient-Dense Foods at United States Marine Corps Food Venues Is Feasible and Profitable
by Katie M. Kirkpatrick, Zina N. Abourjeily, Melissa A. Rittenhouse, Maureen W. Purcell, Rory G. McCarthy and Jonathan M. Scott
Nutrients 2025, 17(15), 2556; https://doi.org/10.3390/nu17152556 - 5 Aug 2025
Abstract
Background/Objectives: Military Service Members (SMs) require optimal nutrition to support health, readiness, and job performance. However, they often fall short of meeting nutrition guidelines. This study aimed to determine the impact and feasibility of implementing the U.S. Marine Corps (USMC) “Fueled to [...] Read more.
Background/Objectives: Military Service Members (SMs) require optimal nutrition to support health, readiness, and job performance. However, they often fall short of meeting nutrition guidelines. This study aimed to determine the impact and feasibility of implementing the U.S. Marine Corps (USMC) “Fueled to Fight®” (F2F) nutrition program in non-appropriated fund (NAF) food venues. Objectives included evaluating changes in Military Nutrition Environment Assessment Tool (mNEAT) scores, feasibility of implementing and maintaining F2F strategies, and influence on customer purchasing patterns. Methods: Researchers conducted a pre-post interventional study from January to December 2024 at three NAF food venues across two USMC bases. F2F strategies, including identifying items using a stoplight color coding system (Green = healthy, Yellow = less healthy, Red = least healthy), menu revisions, food placement, promotion, and marketing, were implemented. Data included mNEAT assessments, sales reports, and stakeholder focus groups. Generalized Estimating Equations models were used to analyze sales data. Results: mNEAT scores increased across all venues post-intervention. Availability and sales of Green items increased, while sales of Red items decreased in some venues. Profit increased at all three food venues. Focus groups revealed feasibility and provided insights for future interventions. Conclusions: F2F interventions in NAF food venues are feasible and can positively impact the food environment and customer purchasing patterns without negatively affecting profit. This study highlights the importance of integrating nutrition programs into all military food venues, not just government-funded dining facilities, to support the nutritional fitness and readiness of SMs. Full article
(This article belongs to the Section Nutrition and Public Health)
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17 pages, 2230 KiB  
Article
Enhancing Diffusion-Based Music Generation Performance with LoRA
by Seonpyo Kim, Geonhui Kim, Shoki Yagishita, Daewoon Han, Jeonghyeon Im and Yunsick Sung
Appl. Sci. 2025, 15(15), 8646; https://doi.org/10.3390/app15158646 (registering DOI) - 5 Aug 2025
Abstract
Recent advancements in generative artificial intelligence have significantly progressed the field of text-to-music generation, enabling users to create music from natural language descriptions. Despite the success of various models, such as MusicLM, MusicGen, and AudioLDM, the current approaches struggle to capture fine-grained genre-specific [...] Read more.
Recent advancements in generative artificial intelligence have significantly progressed the field of text-to-music generation, enabling users to create music from natural language descriptions. Despite the success of various models, such as MusicLM, MusicGen, and AudioLDM, the current approaches struggle to capture fine-grained genre-specific characteristics, precisely control musical attributes, and handle underrepresented cultural data. This paper introduces a novel, lightweight fine-tuning method for the AudioLDM framework using low-rank adaptation (LoRA). By updating only selected attention and projection layers, the proposed method enables efficient adaptation to musical genres with limited data and computational cost. The proposed method enhances controllability over key musical parameters such as rhythm, emotion, and timbre. At the same time, it maintains the overall quality of music generation. This paper represents the first application of LoRA in AudioLDM, offering a scalable solution for fine-grained, genre-aware music generation and customization. The experimental results demonstrate that the proposed method improves the semantic alignment and statistical similarity compared with the baseline. The contrastive language–audio pretraining score increased by 0.0498, indicating enhanced text-music consistency. The kernel audio distance score decreased by 0.8349, reflecting improved similarity to real music distributions. The mean opinion score ranged from 3.5 to 3.8, confirming the perceptual quality of the generated music. Full article
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17 pages, 1738 KiB  
Article
Evaluation of Optimal Visible Wavelengths for Free-Space Optical Communications
by Modar Dayoub and Hussein Taha
Telecom 2025, 6(3), 57; https://doi.org/10.3390/telecom6030057 - 4 Aug 2025
Abstract
Free-space optical (FSO) communications have emerged as a promising complement to conventional radio-frequency (RF) systems due to their high bandwidth, low interference, and license-free spectrum. Visible-light FSO communication, using laser diodes or LEDs, offers potential for short-range data links, but performance is highly [...] Read more.
Free-space optical (FSO) communications have emerged as a promising complement to conventional radio-frequency (RF) systems due to their high bandwidth, low interference, and license-free spectrum. Visible-light FSO communication, using laser diodes or LEDs, offers potential for short-range data links, but performance is highly wavelength-dependent under varying atmospheric conditions. This study presents an experimental evaluation of three visible laser diodes at 650 nm (red), 532 nm (green), and 405 nm (violet), focusing on their optical output power, quantum efficiency, and modulation behavior across a range of driving currents and frequencies. A custom laboratory testbed was developed using an Atmega328p microcontroller and a Visual Basic control interface, allowing precise control of current and modulation frequency. A silicon photovoltaic cell was employed as the optical receiver and energy harvester. The results demonstrate that the 650 nm red laser consistently delivers the highest quantum efficiency and optical output, with stable performance across electrical and modulation parameters. These findings support the selection of 650 nm as the most energy-efficient and versatile wavelength for short-range, cost-effective visible-light FSO communication. This work provides experimentally grounded insights to guide wavelength selection in the development of energy-efficient optical wireless systems. Full article
(This article belongs to the Special Issue Optical Communication and Networking)
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12 pages, 21873 KiB  
Article
Multi-Sensor System for Analysis of Maneuver Performance in Olympic Sailing
by Eirik E. Semb, Erlend Stendal, Karen Dahlhaug and Martin Steinert
Appl. Sci. 2025, 15(15), 8629; https://doi.org/10.3390/app15158629 (registering DOI) - 4 Aug 2025
Abstract
This paper presents a novel multi-sensor system for enhanced maneuver analysis in Olympic dinghy sailing. In the ILCA class, there is an increasing demand for precise in-field measurement and analysis of physical properties beyond well-established velocity and course metrics. The low-cost setup presented [...] Read more.
This paper presents a novel multi-sensor system for enhanced maneuver analysis in Olympic dinghy sailing. In the ILCA class, there is an increasing demand for precise in-field measurement and analysis of physical properties beyond well-established velocity and course metrics. The low-cost setup presented in this study consists of a combination of commercially available sensor systems, such as the AdMos sensor for IMU and GNSS measurement, in combination with custom measurement systems for rudder and mast rotations using fully waterproofed potentiometers. Data streams are synchronized using GNSS time stamping for streamlined analysis. The resulting analysis presents a selection of 12 upwind tacks, with corresponding path overlays, detailed timeseries data, and performance metrics. The system has demonstrated the value of extended data analysis of in situ data with an elite ILCA 7 sailor. The addition of rudder and mast rotations has enabled enhanced analysis of on-water maneuvers for single-handed Olympic dinghies like the ILCA 7, on a level of detail previously reserved for simulated environments. Full article
(This article belongs to the Special Issue Applied Sports Performance Analysis)
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22 pages, 1674 KiB  
Article
Air-STORM: Informed Decision Making to Improve the Success of Solar-Powered Air Quality Samplers in Challenging Environments
by Kyan Kuo Shlipak, Julian Probsdorfer and Christian L’Orange
Sensors 2025, 25(15), 4798; https://doi.org/10.3390/s25154798 - 4 Aug 2025
Abstract
Outdoor air pollution poses a major global health risk, yet monitoring remains insufficient, especially in regions with limited infrastructure. Solar-powered monitors could allow for increased coverage in regions lacking robust connectivity. However, reliable sample collection can be challenging with these systems due to [...] Read more.
Outdoor air pollution poses a major global health risk, yet monitoring remains insufficient, especially in regions with limited infrastructure. Solar-powered monitors could allow for increased coverage in regions lacking robust connectivity. However, reliable sample collection can be challenging with these systems due to extreme temperatures and insufficient solar energy. Proper planning can help overcome these challenges. Air Sampler Solar and Thermal Optimization for Reliable Monitoring (Air-STORM) is an open-source tool that uses meteorological and solar radiation data to identify temperature and solar charging risks for air pollution monitors based on the target deployment area. The model was validated experimentally, and its utility was demonstrated through illustrative case studies. Air-STORM simulations can be customized for specific locations, seasons, and monitor configurations. This capability enables the early detection of potential sampling risks and provides opportunities to optimize monitor design, proactively mitigate temperature and power failures, and increase the likelihood of successful sample collection. Ultimately, improving sampling success will help increase the availability of high-quality outdoor air pollution data necessary to reduce global air pollution exposure. Full article
(This article belongs to the Special Issue Recent Trends in Air Quality Sensing)
20 pages, 2800 KiB  
Article
An Enhanced NSGA-II Driven by Deep Reinforcement Learning to Mixed Flow Assembly Workshop Scheduling System with Constraints of Continuous Processing and Mold Changing
by Bihao Yang, Jie Chen, Xiongxin Xiao, Sidi Li and Teng Ren
Systems 2025, 13(8), 659; https://doi.org/10.3390/systems13080659 - 4 Aug 2025
Abstract
Mixed-flow assembly lines are widely employed in industrial manufacturing to handle diverse production tasks. For mixed flow assembly lines that involve mold changes and greater processing difficulties, there are currently two approaches: batch production and production according to order sequence. The first approach [...] Read more.
Mixed-flow assembly lines are widely employed in industrial manufacturing to handle diverse production tasks. For mixed flow assembly lines that involve mold changes and greater processing difficulties, there are currently two approaches: batch production and production according to order sequence. The first approach struggles to meet the processing constraints of workpieces with higher production difficulty, while the second approach requires the development of suitable scheduling schemes to balance mold changes and continuous processing. Therefore, under the second approach, developing an excellent scheduling scheme is a challenging problem. This study addresses the mixed-flow assembly shop scheduling problem, considering continuous processing and mold-changing constraints, by developing a multi-objective optimization model to minimize additional production time and customer waiting time. As this NP-hard problem poses significant challenges in solution space exploration, the conventional NSGA-II algorithm suffers from limited local search capability. To address this, we propose an enhanced NSGA-II algorithm (RLVNS-NSGA-II) integrating deep reinforcement learning. Our approach combines multiple neighborhood search operators with deep reinforcement learning, which dynamically utilizes population diversity and objective function data to guide and strengthen local search. Simulation experiments confirm that the proposed algorithm surpasses existing methods in local search performance. Compared to VNS-NSGA-II and SVNS-NSGA-II, the RLVNS-NSGA-II algorithm achieved hypervolume improvements ranging from 19.72% to 42.88% and 12.63% to 31.19%, respectively. Full article
(This article belongs to the Section Systems Engineering)
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25 pages, 5488 KiB  
Article
Biased by Design? Evaluating Bias and Behavioral Diversity in LLM Annotation of Real-World and Synthetic Hotel Reviews
by Maria C. Voutsa, Nicolas Tsapatsoulis and Constantinos Djouvas
AI 2025, 6(8), 178; https://doi.org/10.3390/ai6080178 - 4 Aug 2025
Abstract
As large language models (LLMs) gain traction among researchers and practitioners, particularly in digital marketing for tasks such as customer feedback analysis and automated communication, concerns remain about the reliability and consistency of their outputs. This study investigates annotation bias in LLMs by [...] Read more.
As large language models (LLMs) gain traction among researchers and practitioners, particularly in digital marketing for tasks such as customer feedback analysis and automated communication, concerns remain about the reliability and consistency of their outputs. This study investigates annotation bias in LLMs by comparing human and AI-generated annotation labels across sentiment, topic, and aspect dimensions in hotel booking reviews. Using the HRAST dataset, which includes 23,114 real user-generated review sentences and a synthetically generated corpus of 2000 LLM-authored sentences, we evaluate inter-annotator agreement between a human expert and three LLMs (ChatGPT-3.5, ChatGPT-4, and ChatGPT-4-mini) as a proxy for assessing annotation bias. Our findings show high agreement among LLMs, especially on synthetic data, but only moderate to fair alignment with human annotations, particularly in sentiment and aspect-based sentiment analysis. LLMs display a pronounced neutrality bias, often defaulting to neutral sentiment in ambiguous cases. Moreover, annotation behavior varies notably with task design, as manual, one-to-one prompting produces higher agreement with human labels than automated batch processing. The study identifies three distinct AI biases—repetition bias, behavioral bias, and neutrality bias—that shape annotation outcomes. These findings highlight how dataset complexity and annotation mode influence LLM behavior, offering important theoretical, methodological, and practical implications for AI-assisted annotation and synthetic content generation. Full article
(This article belongs to the Special Issue AI Bias in the Media and Beyond)
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25 pages, 30553 KiB  
Article
Optimizing Multi-Cluster Fracture Propagation and Mitigating Interference Through Advanced Non-Uniform Perforation Design in Shale Gas Horizontal Wells
by Guo Wen, Wentao Zhao, Hongjiang Zou, Yongbin Huang, Yanchi Liu, Yulong Liu, Zhongcong Zhao and Chenyang Wang
Processes 2025, 13(8), 2461; https://doi.org/10.3390/pr13082461 - 4 Aug 2025
Abstract
The persistent challenge of fracture-driven interference (FDI) during large-scale hydraulic fracturing in the southern Sichuan Basin has severely compromised shale gas productivity, while the existing research has inadequately addressed both FDI risk reductions and the optimization of reservoir stimulation. To bridge this gap, [...] Read more.
The persistent challenge of fracture-driven interference (FDI) during large-scale hydraulic fracturing in the southern Sichuan Basin has severely compromised shale gas productivity, while the existing research has inadequately addressed both FDI risk reductions and the optimization of reservoir stimulation. To bridge this gap, this study developed a mechanistic model of the competitive multi-cluster fracture propagation under non-uniform perforation conditions and established a perforation-based design methodology for the mitigation of horizontal well interference. The results demonstrate that spindle-shaped perforations enhance the uniformity of fracture propagation by 20.3% and 35.1% compared to that under uniform and trapezoidal perforations, respectively, with the perforation quantity (48) and diameter (10 mm) identified as the dominant control parameters for balancing multi-cluster growth. Through a systematic evaluation of the fracture communication mechanisms, three distinct inter-well types of FDI were identified: Type I (natural fracture–stress anisotropy synergy), Type II (natural-fracture-dominated), and Type III (stress-anisotropy-dominated). To mitigate these, customized perforation schemes coupled with geometry-optimized fracture layouts were developed. The surveillance data for the offset well show that the pressure interference decreased from 14.95 MPa and 6.23 MPa before its application to 0.7 MPa and 0 MPa, achieving an approximately 95.3% reduction in the pressure interference in the application wells. The expansion morphology of the inter-well fractures confirmed effective fluid redistribution across clusters and containment of the overextension of planar fractures, demonstrating this methodology’s dual capability to enhance the effectiveness of stimulation while resolving FDI challenges in deep shale reservoirs, thereby advancing both productivity and operational sustainability in complex fracturing operations. Full article
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13 pages, 2630 KiB  
Article
Photodynamic Therapy in the Management of MDR Candida spp. Infection Associated with Palatal Expander: In Vitro Evaluation
by Cinzia Casu, Andrea Butera, Alessandra Scano, Andrea Scribante, Sara Fais, Luisa Ladu, Alessandra Siotto-Pintor and Germano Orrù
Photonics 2025, 12(8), 786; https://doi.org/10.3390/photonics12080786 (registering DOI) - 4 Aug 2025
Abstract
The aim of this work is to evaluate the effectiveness of antimicrobial photodynamic therapy (aPDT) against oral MDR (multi-drug-resistant) Candida spp. infections related to orthodontic treatment with palatal expanders through in vitro study. Methods: PDT protocol: Curcumin + H2O2 was [...] Read more.
The aim of this work is to evaluate the effectiveness of antimicrobial photodynamic therapy (aPDT) against oral MDR (multi-drug-resistant) Candida spp. infections related to orthodontic treatment with palatal expanders through in vitro study. Methods: PDT protocol: Curcumin + H2O2 was used as a photosensitizer activated by a 460 nm diode LED lamp, with an 8 mm blunt tip for 2 min in each spot of interest. In vitro simulation: A palatal expander sterile device was inserted into a custom-designed orthodontic bioreactor, realized with 10 mL of Sabouraud dextrose broth plus 10% human saliva and infected with an MDR C. albicans clinical isolate CA95 strain to reproduce an oral palatal expander infection. After 48 h of incubation at 37 °C, the device was treated with the PDT protocol. Two samples before and 5 min after the PDT process were taken and used to contaminate a Petri dish with a Sabouraud field to evaluate Candida spp. CFUs (colony-forming units). Results: A nearly 99% reduction in C. albicans colonies in the palatal expander biofilm was found after PDT. Conclusion: The data showed the effectiveness of using aPDT to treat palatal infection; however, specific patient oral micro-environment reproduction (Ph values, salivary flow, mucosal adhesion of photosensitizer) must be further analyzed. Full article
(This article belongs to the Section Biophotonics and Biomedical Optics)
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33 pages, 5056 KiB  
Article
Interpretable Deep Learning Models for Arrhythmia Classification Based on ECG Signals Using PTB-X Dataset
by Ahmed E. Mansour Atwa, El-Sayed Atlam, Ali Ahmed, Mohamed Ahmed Atwa, Elsaid Md. Abdelrahim and Ali I. Siam
Diagnostics 2025, 15(15), 1950; https://doi.org/10.3390/diagnostics15151950 - 4 Aug 2025
Abstract
Background/Objectives: Automatic classification of ECG signal arrhythmias plays a vital role in early cardiovascular diagnostics by enabling prompt detection of life-threatening conditions. Manual ECG interpretation is labor-intensive and susceptible to errors, highlighting the demand for automated, scalable approaches. Deep learning (DL) methods are [...] Read more.
Background/Objectives: Automatic classification of ECG signal arrhythmias plays a vital role in early cardiovascular diagnostics by enabling prompt detection of life-threatening conditions. Manual ECG interpretation is labor-intensive and susceptible to errors, highlighting the demand for automated, scalable approaches. Deep learning (DL) methods are effective in ECG analysis due to their ability to learn complex patterns from raw signals. Methods: This study introduces two models: a custom convolutional neural network (CNN) with a dual-branch architecture for processing ECG signals and demographic data (e.g., age, gender), and a modified VGG16 model adapted for multi-branch input. Using the PTB-XL dataset, a widely adopted large-scale ECG database with over 20,000 recordings, the models were evaluated on binary, multiclass, and subclass classification tasks across 2, 5, 10, and 15 disease categories. Advanced preprocessing techniques, combined with demographic features, significantly enhanced performance. Results: The CNN model achieved up to 97.78% accuracy in binary classification and 79.7% in multiclass tasks, outperforming the VGG16 model (97.38% and 76.53%, respectively) and state-of-the-art benchmarks like CNN-LSTM and CNN entropy features. This study also emphasizes interpretability, providing lead-specific insights into ECG contributions to promote clinical transparency. Conclusions: These results confirm the models’ potential for accurate, explainable arrhythmia detection and their applicability in real-world healthcare diagnostics. Full article
(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
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33 pages, 8886 KiB  
Article
Unsupervised Binary Classifier-Based Object Detection Algorithm with Integrated Background Subtraction Suitable for Use with Aerial Imagery
by Gabija Veličkaitė, Ignas Daugėla and Ivan Suzdalev
Appl. Sci. 2025, 15(15), 8608; https://doi.org/10.3390/app15158608 (registering DOI) - 3 Aug 2025
Viewed by 56
Abstract
This research presents the development of a novel object detection algorithm designed to identify humans in natural outdoor environments using minimal computational resources. The proposed system, SARGAS, combines a custom convolutional neural network (CNN) classifier with MOG2 background subtraction and partial affine transformations [...] Read more.
This research presents the development of a novel object detection algorithm designed to identify humans in natural outdoor environments using minimal computational resources. The proposed system, SARGAS, combines a custom convolutional neural network (CNN) classifier with MOG2 background subtraction and partial affine transformations for camera stabilization. A secondary CNN refines detections and reduces false positives. Unlike conventional supervised models, SARGAS is trained in a partially unsupervised manner, learning to recognize feature patterns without requiring labeled data. The algorithm achieved a recall of 93%, demonstrating strong detection capability even under challenging conditions. However, the overall accuracy reached 65%, due to a higher rate of false positives—an expected trade-off when maximizing recall. This bias is intentional, as missing a human target in search and rescue applications carries a higher cost than producing additional false detections. While supervised models, such as YOLOv5, perform well on data resembling their training sets, they exhibit significant performance degradation on previously unseen footage. In contrast, SARGAS generalizes more effectively, making it a promising candidate for real-world deployment in environments where labeled training data is limited or unavailable. The results establish a solid foundation for further improvements and suggest that unsupervised CNN-based approaches hold strong potential in object detection tasks. Full article
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18 pages, 4799 KiB  
Article
An Adaptive CNN-Based Approach for Improving SWOT-Derived Sea-Level Observations Using Drifter Velocities
by Sarah Asdar and Bruno Buongiorno Nardelli
Remote Sens. 2025, 17(15), 2681; https://doi.org/10.3390/rs17152681 - 3 Aug 2025
Viewed by 60
Abstract
The Surface Water and Ocean Topography (SWOT) mission provides unprecedented high-resolution observations of sea-surface height. However, their direct use in ocean circulation studies is complicated by the presence of small-scale unbalanced motion signals and instrumental noise, which hinder accurate estimation of geostrophic velocities. [...] Read more.
The Surface Water and Ocean Topography (SWOT) mission provides unprecedented high-resolution observations of sea-surface height. However, their direct use in ocean circulation studies is complicated by the presence of small-scale unbalanced motion signals and instrumental noise, which hinder accurate estimation of geostrophic velocities. To address these limitations, we developed an adaptive convolutional neural network (CNN)-based filtering technique that refines SWOT-derived sea-level observations. The network includes multi-head attention layers to exploit information on concurrent wind fields and standard altimetry interpolation errors. We train the model with a custom loss function that accounts for the differences between geostrophic velocities computed from SWOT sea-surface topography and simultaneous in-situ drifter velocities. We compare our method to existing filtering techniques, including a U-Net-based model and a variational noise-reduction filter. Our adaptive-filtering CNN produces accurate velocity estimates while preserving small-scale features and achieving a substantial noise reduction in the spectral domain. By combining satellite and in-situ data with machine learning, this work demonstrates the potential of an adaptive CNN-based filtering approach to enhance the accuracy and reliability of SWOT-derived sea-level and velocity estimates, providing a valuable tool for global oceanographic applications. Full article
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33 pages, 3776 KiB  
Review
The Role of Additive Manufacturing in Dental Implant Production—A Narrative Literature Review
by Ján Duplák, Darina Dupláková, Maryna Yeromina, Samuel Mikuláško and Jozef Török
Sci 2025, 7(3), 109; https://doi.org/10.3390/sci7030109 - 3 Aug 2025
Viewed by 139
Abstract
This narrative review explores the role of additive manufacturing (AM) technologies in the production of dental implants, focusing on materials and key AM methods. The study discusses several materials used in implant fabrication, including porous titanium, trabecular tantalum, zirconium dioxide, polymers, and composite [...] Read more.
This narrative review explores the role of additive manufacturing (AM) technologies in the production of dental implants, focusing on materials and key AM methods. The study discusses several materials used in implant fabrication, including porous titanium, trabecular tantalum, zirconium dioxide, polymers, and composite materials. These materials are evaluated for their mechanical properties, biocompatibility, and suitability for AM processes. Additionally, the review examines the main AM technologies used in dental implant production, such as selective laser melting (SLM), electron beam melting (EBM), stereolithography (SLA), selective laser sintering (SLS), and direct metal laser sintering (DMLS). These technologies are compared based on their accuracy, material limitations, customization potential, and applicability in dental practice. The final section presents a data source analysis of the Web of Science and Scopus databases, based on keyword searches. The analysis evaluates the research trends using three criteria: publication category, document type, and year of publication. This provides an insight into the evolution and current trends in the field of additive manufacturing for dental implants. The findings highlight the growing importance of AM technologies in producing customized and efficient dental implants. Full article
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25 pages, 906 KiB  
Review
Evolution and Prognostic Variables of Cystic Fibrosis in Children and Young Adults: A Narrative Review
by Mădălina Andreea Donos, Elena Țarcă, Elena Cojocaru, Viorel Țarcă, Lăcrămioara Ionela Butnariu, Valentin Bernic, Paula Popovici, Solange Tamara Roșu, Mihaela Camelia Tîrnovanu, Nicolae Sebastian Ionescu and Laura Mihaela Trandafir
Diagnostics 2025, 15(15), 1940; https://doi.org/10.3390/diagnostics15151940 - 2 Aug 2025
Viewed by 200
Abstract
Introduction: Cystic fibrosis (CF) is a genetic condition affecting several organs and systems, including the pancreas, colon, respiratory system, and reproductive system. The detection of a growing number of CFTR variants and genotypes has contributed to an increase in the CF population which, [...] Read more.
Introduction: Cystic fibrosis (CF) is a genetic condition affecting several organs and systems, including the pancreas, colon, respiratory system, and reproductive system. The detection of a growing number of CFTR variants and genotypes has contributed to an increase in the CF population which, in turn, has had an impact on the overall statistics regarding the prognosis and outcome of the condition. Given the increase in life expectancy, it is critical to better predict outcomes and prognosticate in CF. Thus, each person’s choice to aggressively treat specific disease components can be more appropriate and tailored, further increasing survival. The objective of our narrative review is to summarize the most recent information concerning the value and significance of clinical parameters in predicting outcomes, such as gender, diabetes, liver and pancreatic status, lung function, radiography, bacteriology, and blood and sputum biomarkers of inflammation and disease, and how variations in these parameters affect prognosis from the prenatal stage to maturity. Materials and methods: A methodological search of the available data was performed with regard to prognostic factors in the evolution of CF in children and young adults. We evaluated articles from the PubMed academic search engine using the following search terms: prognostic factors AND children AND cystic fibrosis OR mucoviscidosis. Results: We found that it is crucial to customize CF patients’ care based on their unique clinical and biological parameters, genetics, and related comorbidities. Conclusions: The predictive significance of more dynamic clinical condition markers provides more realistic future objectives to center treatment and targets for each patient. Over the past ten years, improvements in care, diagnostics, and treatment have impacted the prognosis for CF. Although genotyping offers a way to categorize CF to direct research and treatment, it is crucial to understand that a variety of other factors, such as epigenetics, genetic modifiers, environmental factors, and socioeconomic status, can affect CF outcomes. The long-term management of this complicated multisystem condition has been made easier for patients, their families, and physicians by earlier and more accurate identification techniques, evidence-based research, and centralized expert multidisciplinary care. Full article
(This article belongs to the Special Issue Advances in the Diagnosis of Inherited/Genetic Diseases)
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