Search Results (845)

Artificial intelligence technologies, particularly machine learning and computer vision, are being increasingly utilized to preserve, restore, and create immersive virtual experiences with cultural artifacts and sites, thus aiding in conserving cultural heritage and making it accessible to a global audience. This paper examines the performance of Generative Adversarial Networks (GAN), especially Style-Based Generator Architecture (StyleGAN), as a deep learning approach for producing realistic images of Egyptian monuments. We used Sigmoid loss for Language–Image Pre-training (SigLIP) as a unique image–text alignment system to guide monument generation through semantic elements. We also studied truncation methods to regulate the generated image noise and identify the most effective parameter settings based on architectural representation versus diverse output creation. An improved discriminator design that combined noise addition with squeeze-and-excitation blocks and a modified MinibatchStdLayer produced 27.5% better Fréchet Inception Distance performance than the original discriminator models. Moreover, differential evolution for latent-space optimization reduced alignment mistakes during specific monument construction tasks by about 15%. We checked a wide range of truncation values from 0.1 to 1.0 and found that somewhere between 0.4 and 0.7 was the best range because it allowed for good accuracy while retaining many different architectural elements. Our findings indicate that specific model optimization strategies produce superior outcomes by creating better-quality and historically correct representations of diverse Egyptian monuments. Thus, the developed technology may be instrumental in generating educational and archaeological visualization assets while adding virtual tourism capabilities. Full article

Brain organoid technology has revolutionized in vitro modeling of human neurodevelopment and disease, providing unprecedented insights into cortical patterning, neural circuit assembly, and pathogenic mechanisms of neurological disorders. Critically, human brain organoids uniquely recapitulate human-specific developmental processes—such as the expansion of outer radial glia and neuromelanin—that are absent in rodent models, making them indispensable for studying human brain evolution and dysfunction. However, a major bottleneck persists: Extended culture periods (≥6 months) are empirically required to achieve late-stage maturation markers like synaptic refinement, functional network plasticity, and gliogenesis. Yet prolonged conventional 3D culture exacerbates metabolic stress, hypoxia-induced necrosis, and microenvironmental instability, leading to asynchronous tissue maturation—electrophysiologically active superficial layers juxtaposed with degenerating cores. This immaturity/heterogeneity severely limits their utility in modeling adult-onset disorders (e.g., Alzheimer’s disease) and high-fidelity drug screening, as organoids fail to recapitulate postnatal transcriptional signatures or neurovascular interactions without bioengineering interventions. We summarize emerging strategies to decouple maturation milestones from rigid temporal frameworks, emphasizing the synergistic integration of chronological optimization (e.g., vascularized co-cultures) and active bioengineering accelerators (e.g., electrical stimulation and microfluidics). By bridging biological timelines with scalable engineering, this review charts a roadmap to generate translationally relevant, functionally mature brain organoids. Full article

This study examines the evolution and integration of Buddhist architecture in East Asia and emphasizes the preservation of indigenous building traditions by adapting pre-Buddhist architectural typologies, vernacular construction techniques, and localized worship practices. In addition, this study highlights the adaptive transformation of Indian Buddhist structures as they incorporate regional architectural forms, resulting in distinct monumental styles that had a profound symbolic significance. By introducing the concept of a cosmopolitan attitude, it underscores the dynamic coexistence and reciprocal influence of universalized and vernacular architectural traditions. The findings highlight the interplay between cultural universality and particularity, illustrating how architectural meaning and intention define the uniqueness of structures beyond their stylistic similarities. This study demonstrates that even when architectural forms appear similar, their function and underlying intent must be considered to fully comprehend their historical and cultural significance. Full article

The rapid evolution of Industry 4.0 technologies has resulted in a scenario in which collaborative networks are essential to overcome the challenges related to their implementation. However, the frameworks to guide such collaborations remain underexplored. This study addresses this gap by proposing Business Rules and Goals Models to operationalize Industry 4.0 solutions through enterprise collaboration. Using the For Enterprise Modeling (4EM) method, the research integrates qualitative insights from expert opinions, including interviews with 12 professionals (academics, industry professionals, and consultants) from Brazilian manufacturing sectors. The Goals Model identifies five main objectives—competitiveness, efficiency, flexibility, interoperability, and real-time collaboration—while the Business Rules Model outlines 18 actionable recommendations, such as investing in digital infrastructure, upskilling employees, and standardizing information technology systems. The results reveal that cultural resistance, limited resources, and knowledge gaps are critical barriers, while interoperability and stakeholder integration emerge as enablers of digital transformation. The study concludes that successfully adopting Industry 4.0 requires technological investments, organizational alignment, structured governance, and collaborative ecosystems. These models provide a practical roadmap for companies navigating the complexities of Industry 4.0, emphasizing adaptability and cross-functional synergy. The research contributes to the literature on collaborative networks by connecting theoretical frameworks with actionable enterprise-level strategies. Full article

Amid ongoing societal development, tourists’ travel behavior patterns have been undergoing substantial transformations, and understanding their evolution has emerged as a key area of scholarly interest. Taking Beijing as a case study, this research aims to uncover the spatiotemporal evolution patterns of tourist flows and their underlying driving mechanisms. Based on digital footprint relational data, a dual-perspective analytical framework—“tourist perception–tourist flow network”—is constructed. By integrating the center-of-gravity model, social network analysis, and regression models, the study systematically examines the dynamic spatial structure of tourist flows in Beijing from 2012 to 2024. The findings reveal that in the post-pandemic period, Beijing tourists place greater emphasis on the cultural connotation and experiential aspects of destinations. The gravitational center of tourist flows remains relatively stable, with core historical and cultural blocks retaining strong appeal, though a slight shift has occurred due to policy influences and emerging attractions. The evolution of the spatial network structure reveals that tourism flows have become more dispersed, while the influence of core scenic spots continues to intensify. Government policy orientation, tourism information retrieval, and the agglomeration of tourism resources significantly promote the structure of tourist flows, whereas the general level of tourism resources exerts no notable influence. These findings offer theoretical insights and practical guidance for the sustainable development and regional coordination of tourism in Beijing, and provide a valuable reference for the spatial restructuring of urban tourism in the post-COVID-19 era. Full article

The essay offers an expansive and multi-stratified investigation into the role of esoteric traditions within the development of Russian modernity, reframing occultism not as an eccentric deviation but as a foundational epistemological regime integral to Russia’s aesthetic, philosophical, and political evolution. By analyzing the arc from Petrine-era alchemical statecraft to the techno-theurgical aspirations of Russian Cosmism and the esoteric visual regimes of the avant-garde, this essay discloses the deep ontological entanglement between sacral knowledge and modernist radical experimentation. The work foregrounds figures such as Jacob Bruce, Wassily Kandinsky, and Kazimir Malevich, situating them within broader transnational currents of Hermeticism, Theosophy, and Rosicrucianism, while interrogating the role of occult infrastructures in both late-imperial and Soviet paradigms. Drawing on recent theoretical frameworks in the global history of esotericism and modernist studies, the long-read article elucidates the metaphysical substrata animating Russian Symbolism, Abstraction, Malevich’s non-Euclidian Suprematism and Moscow Conceptualism. This study contends that esotericism in Russia—far from marginal—served as a generative matrix for radical aesthetic innovation and ideological reconfiguration. It proposes a reconceptualization of Russian cultural history as a palimpsest of submerged sacral structures, where utopia and apocalypse, magic and technology, converge in a distinctively Russian cosmopoietic horizon. Ultimately, this essay reframes Russian and European occultism as an alternate technology of cognition and a performative semiotic universe shaping not only artistic modernism but also the very grammar of Russian historical imagination. Full article

Background: International migration is a growing global phenomenon involving diverse groups, such as labor migrants, international marriage migrants, refugees, and international students. International migrants face unique mental health challenges influenced by adversities such as social isolation and limited access to mental health services. This study employs bibliometric methods to systematically analyze the global body of literature on international migrants’ mental health. Methods: The literature on the mental health of international migrants published until October 2024 was searched using the Web of Science database. The search terms included (‘International migrants’ OR ‘migrant workers’ OR ‘international students’ OR ‘refugees’ OR ‘asylum seekers’ OR ‘smuggled migrants’) AND ‘mental health’. VOSviewer was used to conduct bibliometric analysis, focusing on co-authorship patterns, keyword co-occurrence, and citation networks. Results: Over the past four decades, research on the mental health of international migrants has grown substantially, with major migration destinations such as the United States, Europe, and Australia playing prominent roles in this field. ‘Post-traumatic stress disorder (PTSD)’ was the most frequent keyword in publications, with strong links to ‘trauma’ and ‘depression’. In recent years, with the impact of global socioenvironmental changes and emergencies such as the COVID-19 pandemic, the research focus has gradually shifted towards social support, service accessibility, and cultural adaptation. Conclusions: International migration is a far-reaching global phenomenon, and addressing the mental health of migrant populations is essential for advancing public health, social cohesion, and sustainable development. This study provides the first bibliometric overview of research in this domain, mapping its thematic evolution and collaborative structure. The findings offer valuable insights into the field’s development and may support future interdisciplinary collaboration and the formulation of culturally informed, evidence-based approaches in migrant mental health. Full article

The global burden of hepatitis B virus (HBV) remains high, with ongoing concerted efforts to eliminate viral hepatitis as a public health concern by 2030. The absence of curative treatment against HBV makes it an active area of research to further study HBV pathogenesis. In vitro cell culture systems are essential in exploration of molecular mechanisms for HBV propagation and the development of therapeutic targets for antiviral agents. The lack of an efficient cell culture system is one of the challenges limiting the development and study of novel antiviral strategies for HBV infection. However, the evolution of cell culture systems to study HBV pathogenesis and treatment susceptibility in vitro has made a significant contribution to public health. The currently available cell culture systems to grow HBV have their advantages and limitations, requiring further optimization. The discovery of sodium taurocholate co-transporting polypeptide (NTCP) as a receptor for HBV was a major breakthrough for the development of a robust cell model, allowing the study of de novo HBV infection through NTCP expression in the HepG2 hepatoma cell line. This review is aimed at highlighting the evolution of cell culture systems to study HBV pathogenesis and in vitro treatment susceptibility. Full article

The Three Gorges Reservoir Area (TGRA) is an important ecological barrier and cultural intermingling zone in the upper reaches of the Yangtze River, and its traditional villages carry unique information about natural changes and civilisational development, but face the challenges of conservation and development under the impact of modernisation and ecological pressure. This study takes 112 traditional villages in the TGRA that have been included in the protection list as the research objects, aiming to construct a cultural landscape identification framework for the traditional villages in the TGRA. Through field surveys, landscape feature assessments, GIS spatial analysis, and multi-source data analysis, we systematically analyse their cultural landscape type systems and spatial differentiation characteristics, and then reveal their cultural landscape types and spatial differentiation patterns. (1) The results of the study show that the spatial distribution of traditional villages exhibits significant altitude gradient differentiation—the low-altitude area is dominated by traffic and trade villages, the middle-altitude area is dominated by patriarchal manor villages and mountain farming villages, and the high-altitude area is dominated by ethno-cultural and ecologically dependent villages. (2) Slope and direction analyses further reveal that the gently sloping areas are conducive to the development of commercial and agricultural settlements, while the steeply sloping areas strengthen the function of ethnic and cultural defence. The results indicate that topographic conditions drive the synergistic evolution of the human–land system in traditional villages through the mechanisms of agricultural optimisation, trade networks, cultural defence, and ecological adaptation. The study provides a paradigm of “nature–humanities” interaction analysis for the conservation and development of traditional villages in mountainous areas, which is of practical value in coordinating the construction of ecological barriers and the revitalisation of villages in the reservoir area. Full article

The objective of this research was to conduct a comprehensive review of rainbow trout (Oncorhynchus mykiss) culture in recirculating aquaculture systems (RAS), identify knowledge gaps, and propose strategies oriented towards intelligent and sustainable aquaculture. A systematic review and bibliometric analysis of 387 articles published between 1941 and 2025 in the Scopus database was carried out. Since 2011, there has been a sustained growth in scientific production, with the United States, Denmark, Finland, and Germany standing out as the main contributors. The journals with the highest number of publications were Aquacultural Engineering, Aquaculture, and Aquaculture Research. The conceptual analysis revealed the following three thematic clusters: experimental studies on physiology and metabolism; research focused on nutrition, growth, and yield; and technological developments for water treatment in RAS. This evolution reflects a transition from basic approaches to applied technologies oriented towards sustainability. There was also evidence of a thematic transition toward molecular tools such as proteomics, transcriptomics, and real-time PCR. However, there is still limited integration of smart technologies such as the IoT. It is recommended to incorporate self-calibrating multi-parametric sensors, machine learning models, and autonomous systems for environmental regulation in real time. Full article

This study addresses a critical gap in understanding how mobile banking applications contribute to sustainable development by introducing a novel text mining framework to analyze sustainability dimensions through user-generated content. We analyzed 120,000 reviews from six major Turkish mobile banking applications using an ownership-sensitive analytical approach that integrates structural topic modeling with four sustainability dimensions (environmental, social, governance, and economic). Our analysis reveals significant institutional differences in sustainability approaches: government-owned banks demonstrate substantially stronger overall sustainability orientation (23.43% vs. 11.83% coverage) with pronounced emphasis on social sustainability (+181.7% growth) and economic development (+104.2% growth), while private banks prioritize innovation-focused sustainability. The temporal analysis (2022–2025) shows accelerating sustainability emphasis across all institutions, with distinct evolution patterns by ownership type. Institution-specific sustainability profiles emerge clearly, with each government bank demonstrating distinctive focus areas aligned with historical missions: cultural heritage preservation, agricultural sector support, and small business development. Mapping to Sustainable Development Goals reveals that government banks prioritize development-focused goals (SDGs 1, 8, and 10), while private banks emphasize innovation-focused goals (SDGs 9 and 17). This research makes three key contributions: demonstrating user-generated content as an effective lens for authentic sustainability assessment, establishing ownership-sensitive evaluation frameworks for digital banking sustainability, and providing empirical evidence for contextualized rather than universal sustainability strategies. The findings offer strategic implications for financial institutions, policymakers, and app developers seeking to enhance sustainable digital banking transformation. Full article

Artificial intelligence (AI) is one of the most influential and rapidly developing phenomena of our time. New fields of study are being created at universities, and managers are constantly introducing new AI solutions for business management, marketing, and advertising new products. Unfortunately, AI is also used to promote dangerous political parties and ideologies. The research problem that is the focus of this work is expressed in the following question: How does the symbiotic relationship between artificial and natural intelligence manifest across three dimensions of human experience—philosophical understanding, educational practice, and pastoral care—and what hermeneutical, phenomenological, and critical realist insights can illuminate both the promises and perils of this emerging co-evolution? In order to address this issue, an interdisciplinary research team was established. This team comprised a philosopher, an educator, and a pastoral theologian. This study is grounded in a critical–hermeneutic meta-analysis of the existing literature, ecclesial documents, and empirical investigations on AI. The results of scientific research allow for a broader insight into the impact of AI on humans and on personal relationships in Christian communities. The authors are concerned not only with providing an in-depth understanding of the issue but also with taking into account the ecumenical perspective of religious, social, and cultural education of contemporary Christians. Our analysis reveals that cultivating a healthy symbiosis between artificial and natural intelligence requires specific competencies and ethical frameworks. We therefore conclude with practical recommendations for Christian formation that neither uncritically embrace nor fearfully reject AI, but rather foster wise discernment for navigating this unprecedented co-evolutionary moment in human history. Full article

Adansonia L. (1753) belongs to the family Malvaceae and is commonly known as the baobab tree. This species holds significant cultural and ecological value and is often referred to as the ‘tree of life.’ Although its nuclear genome has been reported, the mitogenome has not yet been studied. Mitogenome research is crucial for understanding the evolution of the entire genome. In this study, we assembled and analyzed the mitogenomes of four Adansonia species by integrating short-read and long-read data. The results showed that the mitogenomes of all four Adansonia species were resolved as single circular sequences. Their total genome lengths ranged from 507,138 to 607,344 bp and contained a large number of repetitive sequences. Despite extensive and complex rearrangements between the mitogenomes of Adansonia and other Malvaceae species, a phylogenetic tree constructed based on protein-coding genes clearly indicated that Adansonia is more closely related to the Bombax. Selection pressure analysis suggests that the rps4 gene in Adansonia may have undergone positive selection compared to other Malvaceae species, indicating that this gene may play a significant role in the evolution of Adansonia. Additionally, by analyzing intracellular gene transfer between the chloroplast, mitochondria, and nuclear genomes, we found that genes from the chloroplast and mitochondria can successfully transfer to each chromosome of the nuclear genome, and the psbJ gene from the chloroplast remains intact in both the mitochondrial and nuclear genomes. This study enriches the genetic information of Adansonia and provides important evidence for evolutionary research in the family Malvaceae. Full article

The preservation and protection of historic urban centers in climate-sensitive coastal areas contributes to the promotion of culture as a driver and enabler of achieving temporal and spatial sustainability, as it is recognized that urban heritage is an integral part of the urban landscape, culture, and economy. The aim of this study was to enhance the resilience and protection of cultural heritage and historic urban centers (HUCs) in the coastal area of Kaštela, Croatia, by providing recommendations and action guidelines in response to climate change impacts, including rising temperatures, sea levels, storms, droughts, and flooding. Preserving HUCs is essential to maintain their cultural values, original structures, and appearance. Many ancient coastal Roman HUCs lie partially or entirely below mean sea level, while low-lying medieval castles, urban areas, and modern developments are increasingly at risk. Based on vulnerability assessments, targeted mitigation and adaptation measures were proposed to address HUC vulnerability sources. The Historical Urban Landscape Approach tool was used to transition and manage HUCs, linking past, present, and future hazard contexts to enable rational, comprehensive, and sustainable solutions. The effective protection of HUCs requires a deeper understanding of the evolution of urban development, climate dynamics, and the natural environments, including both tangible and intangible urban heritage elements. The “hazard-specific” vulnerability assessment framework, which incorporates hazard-relevant indicators of sensitivity and adaptive capacity, was a practical tool for risk reduction. This method relies on analyzing the historical performance and physical characteristics of the system, without necessitating additional simulations of transformation processes. Full article

Studies of prehistoric burials are fundamental for understanding cultural human evolution. Those found in the San Teodoro cave (northeastern Sicily) are significant for the discovery at the turn of the 1930s and 1940s of at least four individuals (ST1–ST4). About 15–16 kyr ago, the bodies of ST1–ST4 were intentionally buried, apparently in a manner original to the context of prehistoric burials, namely by covering them with a continuous layer of red ochre found to connect the graves. Since the earliest excavations, plagued by clandestine digging, there is no material memory of the stratigraphic transition from the burial layer to the subsequent anthropogenic deposit through the red ochre, and nothing certain is known about the orientation of ST3, the presence of grave goods and the ochre cover related to this burial. Moreover, there is no exhaustive knowledge of how much is actually left of the anthropogenic layers described in the old literature. Based on field observations and 3D reconstruction of ST3’s skull position and deposits at the San Teodoro site, we provide insights into anthropological issues, such as the rediscovery of the red ochre vestiges that reasonably covered the ST3 burial, and the burial context of this individual, and shed light on what actually remains of the stratigraphic units described in the 1940s. Full article