Search Results (65,698)

Background: While providing enough sedatives to avoid pain and trauma during surgery is important, studies show a link between the received sedatives and the development of postoperative delirium (POD). Therefore, predicting POD from clinical or physiological data before or during surgery is highly advantageous. This capability enables healthcare providers to proactively implement necessary measures, thereby mitigating or preventing potential complications. Methods: In this study, we focus on patients with Parkinson’s disease undergoing deep brain stimulation surgery who are particularly susceptible to POD. We investigate what aspects of EEG’s power, functional connectivity and complexity during the course of the surgery are influenced by the amount of sedative. Furthermore, we aim to determine whether and to what extent the recorded brain activity during surgery can serve as a reliable means for the prediction of POD in this group of patients. Results and Conclusions: Our results show significant correlations between various power, connectivity and complexity features of EEG and the amount of sedatives. Even though single EEG features are not significantly different between the two groups who either developed or did not develop POD, we show that a classifier based on support vector machines using the selected EEG features could predict POD. Furthermore, our results provide evidence that a classifier trained only on the amount of sedatives is unable to predict POD. Accompanying this paper, our code is published as an open-source toolbox for the analysis of the EEG signal recorded with the four-channel SEDLine Root system, which is among the widely used EEG systems in operation rooms and its recorded data come with challenges that are addressed in our toolbox. Full article

A non-invasive blood glucose monitoring system was developed in this study using near-infrared spectroscopy and an Arduino platform. Reflected signals from near-infrared-focused emissions to a user’s finger are captured via an infrared-tuned photodiode, digitally processed, and displayed on an Android-based application with logging, reminders, and cloud synchronization. Calibrated testing with 20 participants (10 diabetics and 10 non-diabetics) revealed that in the measurement of diabetics, the non-fasting readings showed high average accuracy (99.89%). Non-diabetic trials also demonstrated strong measurement acuity (92.18%), with improved accuracy in non-fasting measurements. The device demonstrates feasibility for affordable, portable, and cloud-connected smart non-invasive glucose tracking. Full article

In order to investigate the effects of bentonite and glass fiber on the macroscopic mechanical properties and microscopic mechanisms of cement soil in dry environments, a series of laboratory tests were conducted in this study, including drying tests under controlled environments (30 °C, 50% humidity), unconfined compressive strength (UCS) tests, digital image processing technology, and scanning electron microscopy (SEM) analyses. The moisture evaporation law, surface crack development process, UCS variation, and microstructure evolution of cement soil with different mix proportions (bentonite content: 0–9%; glass fiber content: 0–0.5%) were systematically analyzed. The results show that bentonite can significantly enhance the water retention capacity of cement soil, reduce the water evaporation rate, and increase the unconfined compressive strength by filling internal pores to densify the microstructure. Glass fibers form a three-dimensional network structure in the matrix, exerting a bridging effect to inhibit crack initiation and propagation, and optimize the mechanical properties. The unconfined compressive strength increases significantly with an increase in bentonite content (3–9%), and the optimal fiber content for strength improvement is determined as 0.3%. The synergistic effect of bentonite and fibers optimizes the interfacial bonding force between fibers and the matrix, which remarkably improves the anti-cracking performance of cement soil. Specifically, when the bentonite content is 6–9% and the fiber content is 0.3–0.5%, the cement soil maintains complete integrity after drying, with no obvious cracks on the surface. SEM analysis reveals that the addition of bentonite and fibers inhibits the expansion and connection of internal voids, avoiding the cycle of “void enlargement–stress concentration–crack propagation”. This study provides a scientific basis for the engineering application of cement soil in a dry environment. Full article

Liquid nitrogen (LN₂) fracturing is a highly promising stimulation technology for unconventional reservoirs. Understanding its in situ fracture network formation mechanism is essential for engineering practice. This study investigates coal rock fracturing driven by the synergistic effect of thermal stress and fluid pressure during LN₂ injection. A coupled thermal–hydraulic–mechanical–damage (THMD) numerical model is developed, incorporating in situ stress conditions and LN₂ phase change behavior. Through true triaxial LN₂ fracturing simulations validated against physical experiments, the multi-field dynamic coupling behavior is systematically analyzed, revealing the synergistic mechanism of fracture propagation and permeability enhancement under cryogenic conditions. The results show the following: (1) The proposed model effectively reproduces the true triaxial LN₂ fracturing process, with simulation results in good agreement with physical experiments. (2) LN₂ fracturing exhibits distinct stage-wise characteristics: cryogenic temperatures induce thermal stress that triggers micro-crack initiation; the self-enhancing effects of damage and permeability significantly promote fracture propagation; fluid pressure then becomes the dominant driving force. (3) Coal rock damage follows a four-stage evolution—wellbore crack initiation, stable propagation, unstable propagation, and through-going failure—ultimately forming a complex spatial fracture network. (4) The horizontal stress ratio is a key factor controlling fracture morphology: a single dominant fracture forms under a high stress difference, whereas a multi-directional complex network develops under equal confining pressure. Fractal analysis reveals significant anisotropy and a non-monotonic stress response in the fracture complexity, reflecting structural evolution from multi-directional propagation to main channel connection. This study provides theoretical support for understanding LN₂ fracturing mechanisms and optimizing field treatment parameters. Full article

In subhumid Mediterranean agroecosystems, runoff drives soil erosion by controlling particle detachment and transport, with its generation and connectivity strongly influenced by land use. In areas affected by land abandonment and reforestation, terracing modifies hillslope morphology and flow pathways, thereby altering soil redistribution patterns. Fallout ¹³⁷Cs has been widely used to assess medium term soil redistribution, and in situ gamma ray spectrometry using scintillation detectors provides an alternative for improving spatial coverage, yet the influence of factors specific to the site on measurements remains insufficiently explored. This study investigates how ¹³⁷Cs counts obtained in situ with a LaBr₃ detector can be used to interpret soil redistribution patterns in two paired catchments that experienced land abandonment since the mid-1960s. Following abandonment, catchment A underwent natural revegetation, whereas catchment B was terraced for reforestation, allowing the effects of water erosion and terracing on soil mobilisation to be analyzed through the spatial distribution of ¹³⁷Cs. By linking ¹³⁷Cs counts with catchment physiography, land use, flow pathways, and NDVI, the study aims to identify the main controls on soil redistribution in both catchments. ¹³⁷Cs counts were significantly higher in catchment A (156.8 ± 108.2 counts) than in catchment B (53.2 ± 68.1), with coefficients of variation of 69% and 128%, respectively. The in situ ¹³⁷Cs measurements provide reliable indicators of soil redistribution patterns controlled not only by runoff but also by anthropogenic modifications of hillslope morphology that alter flow pathways and hydrological connectivity following terracing. The paired catchment approach, combined with in situ ¹³⁷Cs measurements, provides valuable insights into the key controls on soil redistribution, which is essential for effective land management. Full article

The integration of sustainability into strategic management (SSM) has drawn increased academic interest, yet the literature is conceptually fragmented and lacks a cohesive framework that systematically describes the integration of SSM. This study seeks to fill this gap and uncover the essential strategic dimensions, driving forces, and influencing variables that shape the integration of SSM and planning. This study conducts a systematic literature review (SLR) of peer-reviewed articles indexed in the Web of Science and Scopus databases. Through the application of established search parameters and content analysis methodologies, 30 relevant studies are identified and examined. Under a management theory lens, this study synthesizes the literature using a systematic search method and thematic classification approach. The results show that the interaction between internal capabilities and external pressures leads to the formation of sustainable integration. Stakeholder participation, operational integration, governance and leadership commitment, strategy alignment, and sustainability performance evaluation are important factors. The findings also point to important enabling and limiting variables, including the lack of defined measures, regulatory uncertainties, and resource constraints. This study proposes a structured conceptual framework that connects organizational integration mechanisms, strategic drivers, and sustainable results based on these discoveries. This work contributes to the literature on sustainability-oriented strategic management by offering a theory-driven synthesis and highlighting important boundary conditions. It also provides practical implications for practitioners and researchers alike. Full article

Deaths caused by or connected to exposure to Brazilian prisons are widely acknowledged as frequent and preventable, yet official data fails to capture their scale, causes, and circumstances. To circumvent what official administrative datasets miss, this article examines an original dataset of 1077 criminal case files from 27 Brazilian state courts involving individuals who died between 2017 and 2021 after having been incarcerated. Drawing on the systematic document review of these cases, we analyze sociodemographic characteristics, health information, causes of death, and judicial responses, distinguishing between deaths occurring in custody (“internal”) and after release (“external”). Our findings reveal pervasive omissions in basic demographic and medical information, extensive use of ill-defined causes of death, and a striking absence of investigation in most cases, including deaths under direct state custody. We identify instances of obfuscation and judicial inaction that, together with the absence of reliable administrative data, are likely to sustain institutional ignorance and normalize preventable deaths. This study advances debates on incarceration and health, state accountability, and proposes the concept of prison lethality: the capacity of carceral spaces to increase people’s exposure to health risks and harms, combined with the epistemic practices that shed light on or obfuscate this capacity. Full article

The Linpan in western Sichuan is a composite rural landscape of “household-water-forest-field” on the Chengdu Plain. Under the interference of human activities, problems such as landscape fragmentation and ecological function degradation have become increasingly serious, threatening regional ecological security. The specific components involved in the “study on ecological risk sequence” include landscape disturbance degree, landscape vulnerability degree, landscape connectivity, and human activity intensity. Given the lack of long-term ecological risk research on the Linpan landscape in Chongzhou City to support conservation decisions, this study takes it as the object. Based on five phases of land use data from 2003 to 2023, a landscape ecological risk assessment model was constructed. This model is a deterministic and nonlinear comprehensive evaluation model. The determinism is reflected in the fact that, based on specific influencing factors, a unique and definite result can be obtained through a fixed indicator system and calculation method. The nonlinearity is reflected in the fact that the comprehensive risk index does not involve a simple linear superposition of the various factors; instead, the evaluation result is obtained by integrating the factors through nonlinear approaches such as weighted coupling. Using ArcGIS and spatial analysis methods, based on a temporal resolution of 5 years and a spatial resolution of 30 m, the spatiotemporal evolution characteristics were revealed. The results show that: (1) From 2003 to 2023, the Linpan landscape pattern in Chongzhou City underwent significant evolution, characterized by “reduction in agricultural land, expansion of construction land, and slight recovery of ecological land”. Landscape fragmentation intensified, connectivity decreased, but overall aggregation remained stable. (2) The evolution of the landscape pattern drove the ecological risk to show a stable pattern of “low in the northwest and high in the southeast”. The global Moran’s I value decreased from 0.887 to 0.832, indicating that risk aggregation intensified in the early period and was alleviated in the later period. (3) Landscape disturbance degree is the key factor dominating the change in the comprehensive ecological risk index. Compared with similar studies, this research shares the commonality of urbanization-driven fragmentation exacerbation risk, but also exhibits the uniqueness of Linpan structural resilience and conservation policies promoting a reduction in high-risk areas. This study can provide a scientific basis for Linpan protection, land use optimization, and ecological security pattern construction in Chongzhou City. Full article

In the study of sensory processes, the visual system has received the most research compared to other sensory systems. The primary difference between visual and auditory perception lies in the nature of the stimuli and the reception processes: vision perceives electromagnetic radiation, while auditory perception perceives acoustic signals of mechanical origin. This review aims to analyze modern approaches and controversies to the mechanisms of auditory perception related to psychophysics, psychophysiology, psychopathology, modern research on hearing in human–computer interaction (HCI) systems, and machine learning methods. Modern studies of acoustic patterns include a comprehensive assessment of the physical characteristics of perception, complex nonverbal auditory cues, verbalization, perception and memory, as well as individual differences in auditory perception. An analysis of the scientific literature allowed us to conclude that acoustic signals transformed in the brain into auditory images retain (encode) a number of amplitude-temporal parameters of acoustic signals that facilitate auditory discrimination (filtering), but interfere with auditory detection (recognition). Signal processing often, but not necessarily, involves brain regions involved in other forms of perception. It depends on subvocalization, includes semantically interpreted information and expectations, pictorial (visual) and descriptive components, functions as a mnemonic, and is linked to individual musical ability and experience (although the mechanisms of this connection are unclear). Full article

There is a correlation between colonial histories and contemporary migration practices, and this paper examines these transnational enduring connections. Using a qualitative thematic synthesis of existing interdisciplinary sources, this paper argues that the politics of space, migration, and identity in the present cannot be fully comprehended without tracing their colonial genealogies. The findings demonstrate that colonial migrations in all forms (forced, enslaved, or settled) formed transnational genealogies that determine who moves, who is stopped, who belongs, and who is an outsider. The paper concludes that understanding current migration politics, spatial inequalities, and identities requires an appreciation of transnational genealogies that connect the past to the present. The paper suggests that colonial history is more than a background but a framework that sets the conditions within which migration occurs today. This paper contributes to showing that family functions as a neglected site where genealogies are transmitted and contested across generations. Full article

With the vigorous promotion of the modernization of China’s construction industry, the proportion of prefabricated buildings in new construction projects has increased steadily. Grouted sleeve connection is a mainstream joining method for prefabricated components, and the performance of grouting materials is crucial to connection reliability. In this study, a modified polyurethane composite (MPC) was developed as a novel sleeve grouting material, and seven grouted splice specimens with different steel bar strength grades and anchorage lengths were fabricated for uniaxial tensile tests. The mechanical properties of MPC and the connection performance of specimens were systematically investigated, and the effects of steel bar strength grade and anchorage length on ultimate load, average bond strength, and strain characteristics were quantitatively analyzed. The results show that MPC has excellent fluidity, and its mechanical strengths meet the specified requirements. Increasing steel bar strength grade and anchorage length significantly improves ultimate load: at a 6d anchorage length, the ultimate load of the S600 series (HRB600E) is 44.85% higher than that of the S400 series (HRB400E); extending the S400 series’ anchorage length from 4d to 8d increases ultimate load by 50.61%. Average bond strength decreases with increasing anchorage length (S400-MPC-8d is 24.70% lower than S400-MPC-4d) but increases with higher steel bar strength grade (S600-MPC-6d is 32.37% higher than S400-MPC-6d). The sleeve remains elastic during the test, ensuring safety. Prediction formulas for average bond strength under slip failure were established, with good agreement between predicted and experimental results. For both HRB400E and HTRB600E steel bars, considering safety and installation errors, a critical anchorage length of 8d is recommended for engineering design. Full article

Populations of several billfish species are declining due to overfishing and bycatch, and fundamental aspects of their biology and population dynamics remain poorly understood. We provide the first assessment of the population genetic structure of longbill spearfish (Tetrapturus pfluegeri) in the western Atlantic Ocean. We screened variation at 12 nuclear microsatellite loci (n = 144) and mitochondrial DNA control region sequences (mtCR, n = 177). Both marker types revealed three genetically differentiated clusters, with mean values for microsatellites showing differentiation of F_ST = 0.136 and D_EST = 0.201, and for mtCR F_ST = 0.645. Microsatellite markers demonstrated moderate-to-high genetic diversity, with a mean allelic richness of 6.73 alleles per locus, moderate heterozygosities (Ho = 0.446, He = 0.604), and a positive inbreeding coefficient (F_IS = 0.22) across the three sample collection sites. The overall estimated effective population size was 789.2 (95% CI: 246.7–∞). The mtCR exhibited 96 haplotypes, with high haplotype (0.989 ± 0.003) and nucleotide (0.025 ± 1.3%) diversities. We found higher mean relatedness within clusters than among them, supporting the interpretation of population subdivision and the Wahlund effect. Tajima’s D and Fu’s Fs were negative across all localities, with significant values observed along the Brazilian coast but not in the Caribbean Sea. These neutrality test results, together with low Harpending’s raggedness indices from DNA sequence mismatch distributions, are consistent with historical demographic expansion. Our findings establish a genetic baseline for fishery monitoring and management, contributing to the conservation of T. pfluegeri populations in the western Atlantic Ocean. Full article

This research article explores whether the climate transition risk (CTR) and climate physical risk (CPR) transmit greater shocks towards the sustainable, gold-backed, energy-related and Sharia-compliant cryptocurrencies during bullish market conditions as compared with the normal and bearish market conditions. We employ the novel quantile vector auto-regression (QVAR)-based connectivity framework. Overall findings suggested that CPR and CTR transmitted greater shocks towards cryptocurrency classes during extremely high and lower quantiles as compared with the median quantile. This U-shaped and non-linear climate risks shock transmission indicates that Sharia-compliant, energy-related and gold-backed cryptocurrencies become more vulnerable during extreme market conditions (higher and lower quantiles) and may not consistently serve as reliable hedging or diversification instruments, particularly during periods of heightened climate uncertainty. Overall findings suggested that both the CPR and CTR transmitted greater shocks towards energy-related, gold-backed, and Sharia-compliant cryptocurrencies as compared with the sustainable cryptocurrencies, across all the quantiles. Therefore, sustainable cryptocurrencies, particularly those with energy-efficient consensus mechanisms such as Stellar, Cardano and Ripple, exhibited resilience to climate risks and can therefore function as stabilizing core holdings in diversified portfolios. Fund managers should incorporate a rebalancing strategy that increases allocation to these climate-resilient, sustainable digital assets during periods of elevated climate risk. Fund managers should integrate CPR and CTR into the quantile-domain forecasting frameworks for predicting digital asset market returns to enhance financial stability. Portfolio managers should undertake dynamic and quantile-contingent climate risk hedging strategies that account for tail-risk exposure rather than relying on average market behavior. Full article

Conserved lands play a central role in sustaining ecological functions within working agricultural regions, yet their capacity to maintain wetland conditions varies widely depending on hydrologic persistence and seasonal dynamics. This study assesses the hydrologic performance of Nebraska’s major conservation programs using multi-year Sentinel-2 satellite observations spanning from 2018 to 2024. Five land-protection categories were evaluated: the Wetlands Reserve Program (WRP), Wildlife Management Areas (WMAs), Waterfowl Production Areas (WPAs), the Conservation Reserve Program (CRP), and additional protected lands mapped in the Protected Areas Database of the United States (PAD-US). To capture hydrologic dynamics across scales, we quantified parcel-level inundation percentages alongside program-level wetness metrics that represent cumulative surface-water extent. Lands enrolled in WRP and WPA generally exhibited higher inundation levels at the 0% threshold across annual and seasonal periods, with variability across programs, reflecting their role in wetland restoration and habitat provision. WMAs showed greater seasonal variability but retained water under higher persistence thresholds (≥25% and ≥50%), underscoring their importance in maintaining semi-permanent wetland conditions during drier periods. Wetland-associated CRP lands provide essential short-duration wetness that supports regional hydrologic connectivity across working agricultural landscapes. Similar seasonal patterns were observed across other protected lands, which generally contributed to episodic surface water rather than long-term hydrologic storage. Seasonal analyses highlighted strong intra-annual variability driven by snowmelt, precipitation regimes, and evapotranspiration. Collectively, the results demonstrate substantial differences in hydrologic function among conservation programs and provide an empirical basis for prioritizing investments toward lands that most effectively sustain wetland habitats and water-quality benefits. Full article

Background/Objectives: The human gastrointestinal tract is a dynamic and interactive micro-ecosystem, with its distinct microbial population residing in the gut. The healthy condition of the gut is integrated into the normal functioning of all physiological activities. The gut microbiome is critical for the functioning of metabolism via several gut-axis connections with different systems in the human body; thus, it affects the status of health and general well-being. The fundamental physiology and homeostatic shifts are associated with specific diseases caused by a disrupted balance in the diversity of the gut microbiome, which could be due to a condition of dysbiosis in a host, instigated by several reasons. Some studies have been conducted on the selective isolation of probiotic species from dairy and other food sources to obtain effective probiotic strains, which have been studied and used by dietary intake strategies to restore gut microbial diversity, which is disturbed by some disease/s. Methods: Our search strategy included specific keywords—gut, microbiota, microbiome, disease, dysbiosis, probiotic bacteria and yeast—and was based on a timeframe of 15 years in the web-based electronic databases of PubMed, Scopus, and Web of Science. Among the few hundred results, a secondary screening was conducted to select references on probiotics studied for disease management with preclinical evidence and some reports on clinically validated outcomes; we excluded the search results for screening fermented foods for taxonomy studies of isolated probiotics. Results: The summarised information using two figures and two tables has been presented in this article from the review of 137 selected references: >75% have been published in the last 10 years. Conclusions: Further advances in modelling and analysis of the gut microbiota are required to understand their influence on the occurrence of certain diseases; this approach will allow us to establish research strategies for filling knowledge gaps, inconsistencies in clinical evidence, or limitations in translating probiotic effects from experimental models to humans. Full article