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Article

2,889 Views

19 Pages

Metabolic Heterogeneity in Diffuse Large B-Cell Lymphoma Cells Reveals an Innovative Antimetabolic Combination Strategy

Leonardo Lordello,
Stéphanie Nuan-Aliman,
Karoline Kielbassa-Elkadi,
Aurélie Montagne,
Konstantina Kotta,
Isabelle Martins,
Eva Pinto Jurado,
Cédric Caradeuc,
Jacqueline Lehmann-Che and
Véronique Baud
+ 6 authors

Cancers2025, 17(3), 394;https://doi.org/10.3390/cancers17030394

24 January 2025

Background/Objectives: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, characterized by aggressive and heterogeneous tumors originating from B-cells. Especially in patients with relapsed or refractory (R/R) dise...

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Review

16 Citations

6,339 Views

26 Pages

Colostrum Proteins in Protection against Therapy-Induced Injuries in Cancer Chemo- and Radiotherapy: A Comprehensive Review

Jolanta Artym and
Michał Zimecki

Biomedicines2023, 11(1), 114;https://doi.org/10.3390/biomedicines11010114

3 January 2023

In this article, we review the benefits of application of colostrum and colostrum-derived proteins in animal models and clinical trials that include chemotherapy with antimetabolic drugs, radiotherapy and surgical interventions. A majority of the rep...

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Article

2 Citations

2,149 Views

15 Pages

Fatty Acid Metabolism Provides an Essential Survival Signal in OxPhos and BCR DLBCL Cells

Aurélie Montagne,
Konstantina Kotta,
Karoline Kielbassa-Elkadi,
Isabelle Martins,
José Ángel Martinez-Climent,
Guido Kroemer,
Catherine Thieblemont and
Véronique Baud

Biomedicines2025, 13(3), 707;https://doi.org/10.3390/biomedicines13030707

13 March 2025

Backgroung/objectives: Diffuse large B-cell lymphoma (DLBCL) is the most frequent subtype of malignant lymphoma and is a heterogeneous disease with various gene and chromosomal abnormalities. The development of novel therapeutic treatments has improv...

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Article

6 Citations

3,232 Views

19 Pages

Metabolic Adaptation as Potential Target in Papillary Renal Cell Carcinomas Based on Their In Situ Metabolic Characteristics

Ildikó Krencz,
Enikő Vetlényi,
Titanilla Dankó,
Gábor Petővári,
Dorottya Moldvai,
Dániel Sztankovics,
Regina Raffay,
Katalin Mészáros,
Endre Sebestyén and
Anna Sebestyén
+ 2 authors

Int. J. Mol. Sci.2022, 23(18), 10587;https://doi.org/10.3390/ijms231810587

13 September 2022

Metabolic characteristics of kidney cancers have mainly been obtained from the most frequent clear cell renal cell carcinoma (CCRCC) studies. Moreover, the bioenergetic perturbances that affect metabolic adaptation possibilities of papillary renal ce...

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Article

16 Citations

3,869 Views

26 Pages

In Situ Metabolic Characterisation of Breast Cancer and Its Potential Impact on Therapy

Gábor Petővári,
Titanilla Dankó,
Anna-Mária Tőkés,
Enikő Vetlényi,
Ildikó Krencz,
Regina Raffay,
Melinda Hajdu,
Dániel Sztankovics,
Krisztina Németh and
Anna Sebestyén
+ 3 authors

Cancers2020, 12(9), 2492;https://doi.org/10.3390/cancers12092492

3 September 2020

In spite of tremendous developments in breast cancer treatment, the relatively high incidence of relapsing cases indicates a great need to find new therapeutic strategies in recurrent, metastatic and advanced cases. The bioenergetic needs of growing...

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