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LncRNA Profiling Reveals That the Deregulation of H19, WT1-AS, TCL6, and LEF1-AS1 Is Associated with Higher-Risk Myelodysplastic Syndrome
- Katarina Szikszai,
- Zdenek Krejcik,
- Jiri Klema,
- Nikoleta Loudova,
- Andrea Hrustincova,
- Monika Belickova,
- Monika Hruba,
- Jitka Vesela,
- Viktor Stranecky and
- Michaela Dostalova Merkerova
- + 3 authors
Background: myelodysplastic syndrome (MDS) is a hematopoietic stem cell disorder with an incompletely known pathogenesis. Long noncoding RNAs (lncRNAs) play multiple roles in hematopoiesis and represent a new class of biomarkers and therapeutic targe...