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11 Results Found

  • Article
  • Open Access
18 Citations
4,734 Views
18 Pages

Compounding Tailored Veterinary Chewable Tablets Close to the Point-of-Care by Means of 3D Printing

  • Erica Sjöholm,
  • Rathna Mathiyalagan,
  • Xiaoju Wang and
  • Niklas Sandler

Certain patient populations receive insufficient medicinal treatment due to a lack of commercially available products. The number of approved veterinary products is limited, making animals a patient population with suboptimal medicinal treatments ava...

  • Review
  • Open Access
863 Views
35 Pages

Three-Dimensional Printing in Paediatrics: Innovative Technology for Manufacturing Patient-Centred Drug Delivery Systems

  • Nadine Couți,
  • Sonia Iurian,
  • Alina Porfire,
  • Tibor Casian,
  • Rareș Iovanov and
  • Ioan Tomuță

Additive manufacturing can be regarded as a game-changing approach for paediatric drug development, as children have special drug-related requirements which are rarely met by conventional technologies. Traditional dosage forms have considerable drawb...

  • Article
  • Open Access
49 Citations
21,699 Views
16 Pages

Natural Ingredients-Based Gummy Bear Composition Designed According to Texture Analysis and Sensory Evaluation In Vivo

  • Ugnė Čižauskaitė,
  • Greta Jakubaitytė,
  • Virgilijus Žitkevičius and
  • Giedrė Kasparavičienė

11 April 2019

The increased interest in functional materials of natural origin has resulted in a higher market demand for preservative-free, “clean label”, or natural ingredients-based products. The gummy bear food supplements are more acceptable to co...

  • Review
  • Open Access
47 Citations
17,019 Views
36 Pages

Innovations in Chewable Formulations: The Novelty and Applications of 3D Printing in Drug Product Design

  • Lucía Rodríguez-Pombo,
  • Atheer Awad,
  • Abdul W. Basit,
  • Carmen Alvarez-Lorenzo and
  • Alvaro Goyanes

Since their introduction, chewable dosage forms have gained traction due to their ability to facilitate swallowing, especially in paediatric, geriatric and dysphagia patients. Their benefits stretch beyond human use to also include veterinary applica...

  • Article
  • Open Access
82 Citations
8,751 Views
15 Pages

Embedded 3D Printing of Novel Bespoke Soft Dosage Form Concept for Pediatrics

  • Katarzyna Rycerz,
  • Krzysztof Adam Stepien,
  • Marta Czapiewska,
  • Basel T. Arafat,
  • Rober Habashy,
  • Abdullah Isreb,
  • Matthew Peak and
  • Mohamed A. Alhnan

Embedded three-dimensional printing (e-3DP) is an emerging method for additive manufacturing where semi-solid materials are extruded within a solidifying liquid matrix. Here, we present the first example of employing e-3DP in the pharmaceutical field...

  • Article
  • Open Access
1 Citations
3,795 Views
16 Pages

Gummy formulations are defined as gradually or slowly released solid oral dosage forms. Risperidone is an atypical antipsychotic medication used to treat schizophrenia and autism-related irritability. This study presents the development of visually a...

  • Article
  • Open Access
5 Citations
2,021 Views
20 Pages

Background/Objectives: Semi-solid extrusion (SSE) 3D printing is an innovative method utilized for preparation of various drug dosage forms, allowing for individualization by means of incorporation of one or multiple drugs in adjustable doses. SSE pr...

  • Review
  • Open Access
9 Citations
4,436 Views
21 Pages

3D Printing of Dietary Products for the Management of Inborn Errors of Intermediary Metabolism in Pediatric Populations

  • Paola Carou-Senra,
  • Lucía Rodríguez-Pombo,
  • Einés Monteagudo-Vilavedra,
  • Atheer Awad,
  • Carmen Alvarez-Lorenzo,
  • Abdul W. Basit,
  • Alvaro Goyanes and
  • María L. Couce

25 December 2023

The incidence of Inborn Error of Intermediary Metabolism (IEiM) diseases may be low, yet collectively, they impact approximately 6–10% of the global population, primarily affecting children. Precise treatment doses and strict adherence to presc...

  • Article
  • Open Access
116 Citations
8,445 Views
16 Pages

I Spy with My Little Eye: A Paediatric Visual Preferences Survey of 3D Printed Tablets

  • Patricija Januskaite,
  • Xiaoyan Xu,
  • Sejal R. Ranmal,
  • Simon Gaisford,
  • Abdul W. Basit,
  • Catherine Tuleu and
  • Alvaro Goyanes

3D printing (3DP) in the pharmaceutical field is a disruptive technology that allows the preparation of personalised medicines at the point of dispensing. The paediatric population presents a variety of pharmaceutical formulation challenges such as d...

  • Review
  • Open Access
9 Citations
4,223 Views
34 Pages

Paediatric infectious diseases contribute significantly to global health challenges. Conventional therapeutic interventions are not always suitable for children, as they are regularly accompanied with long-standing disadvantages that negatively impac...

  • Article
  • Open Access
19 Citations
7,561 Views
12 Pages

Intake of Sugar Substitute Gummy Candies Benefits the Glycemic Response in Healthy Adults: A Prospective Crossover Clinical Trial

  • Dan Gan,
  • Minjun Xu,
  • Ling Chen,
  • Shaohua Cui,
  • Changyong Deng,
  • Qian Qiao,
  • Ruimiao Guan and
  • Fang Zhong

10 October 2022

Sugar reduction in food has attracted great health concerns worldwide. Gummies have been one of the most popular and highly favored candies due to their chewable properties, simplicity to swallow, and delicious taste. The general perception is that g...