Search Results (133)

Superficial fungal infections of the feet, such as tinea pedis and onychomycosis, are highly prevalent and frequently recurrent, often due to persistent contamination of footwear, textiles, and foot care instruments. Despite growing concern over antifungal resistance, environmental sources of reinfection remain under-recognized in clinical practice. This review critically examines historical and contemporary methods used to sanitize shoes, socks, podiatric tools, and related materials. Evidence from peer-reviewed studies published between 1938 and 2025 was analyzed across multiple disinfection categories, including chemical agents, thermal methods, laundering, ultraviolet- and ozone-based technologies, antimicrobial textiles, and sterilization protocols. Findings reveal a range of efficacies, limitations, and practical considerations across methods, with steam sterilization emerging as the most reliable for reusable instruments. A multifaceted approach combining pharmacologic treatment with consistent environmental hygiene is essential for breaking reinfection cycles and reducing antifungal resistance. This review highlights the need for clinical education and research into scalable, effective disinfection strategies. Full article

Background/Objective: Fentanyl plays a pivotal role in the opioid epidemic, defined by four waves of overdose deaths. To analyse fentanyl research trends, examining its links to mental health, pharmaceutical development, healthcare, diseases, and pathophysiology within the broader social and health context of the time. Methods: To understand the evolution of scientific publications on fentanyl and its relationship to the opioid crisis, a search using Web of Science Core Collection and PubMed was conducted. A total of 53,670 documents were retrieved related to opioid scientific production, among which 1423 articles (3%) focused specifically on fentanyl. The 21,546 MeSH terms identified in these documents were analysed by publication year and specific fields: Psychiatry and Psychology, Chemicals and Drugs, Healthcare, Diseases, and Phenomena and Processes. R-statistical/FactoMineR libraries were used for the correspondence analysis. Results: In the first overdose death wave, research focused on improving therapies and reducing side effects. The second wave emphasised detoxification methods with naltrexone, methadone, and behavioural therapies. The third wave addressed psychological treatments and HIV-syringe-sharing prevention. The fourth wave prioritised less addictive analogues and understanding consumer profiles to combat the epidemic. Conclusions: Fentanyl research has evolved alongside real-world challenges, reinforcing the connection between patients’ needs, healthcare professionals’ roles, illicit users, policymakers, and the research community’s contributions to addressing both therapeutic use and its broader societal impact. These findings highlight the necessity for an interdisciplinary approach to scientific research integrating prevention, treatment, education, legal reform, and social support, emphasising the need for public health policies and collaborative research to mitigate its impact. Full article

The last decade has seen a transformative advancement in computational technologies, enabling the precise creation, evaluation, visualization, and reproduction of high-fidelity three-dimensional (3D) models of archaeological sites and artefacts. With the advent of 3D printing, both small- and large-scale objects can now be reproduced with remarkable accuracy and at customizable scales. Artefacts composed of organic materials—such as wood—are inherently susceptible to biological degradation and thus require extensive, long-term conservation employing costly methodologies. These procedures often raise environmental concerns and lead to irreversible alterations in the wood’s chemical composition, dimensional properties, and the intangible essence of the original artefact. In the context of public education and the dissemination of knowledge about historical technologies and objects, 3D replicas can effectively fulfill the same purpose as original artefacts, without compromising interpretative value or cultural significance. Furthermore, the digital data embedded in 3D surface and object models provides a wealth of supplementary information that cannot be captured, preserved, or documented through conventional techniques. Waterlogged wooden objects can now be thoroughly documented in 3D, enabling ongoing, non-invasive scientific analysis. Given these capabilities, it is imperative to revisit the philosophical and ethical foundations of preserving waterlogged wood and to adopt innovative strategies for the conservation and presentation of wooden artefacts. These new paradigms can serve educational, research, and outreach purposes—core functions of contemporary museums. Full article

The advent of generative artificial intelligence (GenAI) has significantly transformed the educational landscape. While GenAI offers benefits such as convenient access to learning resources, it also introduces potential risks. This study explores the phenomenon of learning burnout among university students resulting from the misuse of GenAI in this context. A questionnaire was designed to assess five key dimensions: information overload and cognitive load, overdependence on technology, limitations of personalized learning, shifts in the role of educators, and declining motivation. Data were collected from 143 students across various majors at Shandong Institute of Petroleum and Chemical Technology in China. In response to the issues identified in the survey, the study proposes several teaching strategies, including cheating detection, peer learning and evaluation, and anonymous feedback mechanisms, which were tested through experimental teaching interventions. The results showed positive outcomes, with students who participated in these strategies demonstrating improved academic performance. Additionally, two rounds of surveys indicated that students’ acceptance of additional learning tasks increased over time. This research enhances our understanding of the complex relationship between GenAI and learning burnout, offering valuable insights for educators, policymakers, and researchers on how to effectively integrate GenAI into education while mitigating its negative impacts and fostering healthier learning environments. The dataset, including detailed survey questions and results, is available for download on GitHub. Full article

The intensification of agricultural production due to high global demand has led to uncontrolled waste production from this industry, creating an environmental imbalance due to inadequate waste management. In developing regions, the lack of access to electricity has become a critical problem, affecting people’s health, education, and economy. To address this issue, alternative and sustainable ways of generating electricity have been explored. This research focuses on the potential of using asparagus waste in single-chamber microbial fuel cells (MFCs) at different pH levels (4, 4.7—target, 7, and 9) to achieve optimal performance. It has been demonstrated that using this substrate, the MFC at pH 7 obtained the best results on the seventh day, generating an electric current of 4.859 mA and a maximum voltage of 0.965 V. The substrate showed an oxidation-reduction potential of 312.821 mV, a chemical oxygen demand reduction of 76.47%, and an electrical conductivity of 254.854 mS/cm. Additionally, it managed to generate a power density of 2.149 mW/cm² at a current density of 5.979 mA/cm². MFCs at different pH levels (4, 4.7—target, 7, and 9) demonstrated their potential to generate electrical energy by powering an LED light when connected in series. This research holds promise in promoting sustainable energy solutions for the future. Full article

Based on the interpretation of the identified risk biases from a narrative perspective, this paper studies the biases in safety and security risk management of chemical-related academic laboratories from four parts: risk identification, risk assessment, risk control and continuous monitoring. Mainly systematic error, inclusion of risk events, cognitive factors, model/algorithmic and social/interpersonal during risk management are discussed. The bias related to uncertain risk events, which is the most common and easily ignored during risk management, mainly including the imbalance between safety risk management and security risk management. Therefore, while protecting the laboratory from unintentional and unpremeditated safety risks within the system, it is also critical to protect the system from external, deliberate and premeditated security risks. This research paper is expected to spur and promote more discussion and the best practices in laboratory risk management among researchers, educators, managers and other stakeholders for handling biases in the risk management of chemical-related academic laboratories. Full article

This study examines the Chemical Engineering and Technology major at Nanjing Forestry University as a case study to explore a sustainable improvement and development model for the major, grounded in the principles of Outcome-Based Education (OBE) and the Plan-Do-Check-Act (PDCA) framework. In the context of new engineering education and integrating the core concepts of engineering professional education accreditation, this research merges the OBE concept with the PDCA model to promote the sustainable enhancement of the Chemical Engineering and Technology major. The objective is to assess the effectiveness of this professional construction model based on the OBE and PDCA framework in fostering the sustainable development of students. The findings indicate that by establishing a cultivation system aligned with the new economy, restructuring the interdisciplinary curriculum, and implementing a diversified evaluation system, it is feasible to nurture high-quality technical engineering talents equipped with social responsibility, teamwork skills, innovative thinking, and an awareness of sustainable development. This study demonstrates that this professional construction mechanism and model significantly contribute to developing sustainable education, enhancing engineering practice and innovative awareness, and cultivating applied innovative talents among students. Furthermore, this study not only offers new insights for specialty construction but also serves as a practical reference for improving teaching quality and meeting societal demands. Full article

In response to the urgent need for the sustainable conservation of cultural heritage against the backdrop of climate change and environmental degradation, this study proposes a low-cost, non-destructive digital recording method for murals based on close-range photogrammetry. By integrating non-metric digital cameras, total stations, and spatial coordinate transformation models, high-precision digital orthophoto generation for indoor murals was achieved. Experimental results show that the resolution error of this method is 0.02 mm, with root mean square errors (RMSE) of 3.51 mm and 2.77 mm in the X and Y directions, respectively, meeting the precision requirements for cultural heritage conservation. Compared to traditional laser scanning technology, the energy consumption of the equipment in this study is significantly reduced, and the use of chemical reagents is avoided, thereby minimizing the carbon footprint and environmental impact during the recording process. This provides a green technological solution to address climate change. Additionally, the low-cost nature of non-metric cameras offers a feasible option for cultural heritage conservation institutions with limited resources, promoting equity and accessibility in heritage protection amid global climate challenges. This technology provides sustainable data support for long-term monitoring, virtual restoration, and public digital display of murals while also offering rich data resources for virtual cultural tourism, public education, and scientific research. It demonstrates broad application potential in the context of climate change and environmental protection, contributing to the green transformation and sustainable development of cultural tourism. Full article

Environmental degradation combined with the need to ensure food security for a rapidly growing world population has prompted the adoption of Sustainable Weed Management Practices (SWMPs), which are expected to reduce crop losses while preserving natural resources. However, evidence shows that farmers are reluctant to adopt them, and European farming remains dependent on chemical herbicides. The objective of this study is to analyze the adoption of SWMPs in Greece by identifying common factors that may explain the information (variance) included in each of two initial sets of variables, separately describing the following: (i) factors that hinder the adoption of SWMPs in Greece; (ii) factors and strategies to promote the use of SWMPs in the country. To achieve this purpose, 121 farmers cultivating annual arable crops in the Region of Thessaly in Central Greece were surveyed by means of a structured questionnaire. Using Principal Component Analysis (PCA) to reduce both initial sets of variables and categorize farmers’ responses into two smaller sets of uncorrelated components (dimensions) without missing valuable information, the analysis yielded five factors that limit the adoption of SWMPs (“Costs and availability of resources”; “Environment and land ownership”; “Compatibility and easiness of use”; “Economic performance”; “Social capital and education”) as well as four factors to promote their use (“Policy, research and Cooperatives”; “Training and mandatory regulations”; “Technology and networking”; “Targeted approaches”). The derived factors can be used in terms of policy objectives, as each dimension represents different aspects to be considered when developing effective strategies and integrated policies for the evolution and further expansion of SWMPs. Full article

Antimicrobial resistance (AMR) is an urgent global health threat with many anthropogenic drivers outside of healthcare. The impacts of modern agriculture on human health are manifold, from the food systems and dietary patterns they support to the less apparent effects of environmental stresses and biodiversity loss in ecosystems. Intensive practices, such as chemical fertilizers, pesticides, and herbicides, induce abiotic stresses that deplete biodiversity and drive AMR in soil and aquatic microbiomes. The overuse of antibiotics in livestock production is another major driver of AMR. Changes in weather patterns due to climate change have the potential to exacerbate these issues as warmer and wetter weather increases the potential for bacterial infection. While practices exist to address healthcare-associated drivers, the impact of agriculture and environmental destruction are not widely appreciated in healthcare and biomedical sciences. It is imperative that healthcare professionals and public health experts understand these connections to properly address the emergent issue of AMR. This review aims to summarize the current data on important agricultural and environmental drivers of AMR for educational purposes, to fill gaps in knowledge, and to improve current practices and stimulate further research. Full article

Long-term intensive agricultural management practices have led to a continuous decline in farmland soil quality, posing a serious threat to food security and agricultural sustainability. Green manure, as a natural, cost-effective, and environmentally friendly cover crop, plays a significant role in enhancing soil quality, ensuring food security, and promoting sustainable agricultural development. The improvement of soil quality by green manure is primarily manifested in the enhancement of soil physical, chemical, and biological properties. Specifically, it increases soil organic matter content, optimizes soil structure, enhances nutrient cycling, and improves microbial community composition and metabolic activity. The integration of green manure with agronomic practices such as intercropping, crop rotation, conservation tillage, reduced fertilizer application, and organic material incorporation demonstrates its potential in addressing agricultural development challenges, particularly through its contributions to soil quality improvement, crop yield stabilization, water and nutrient use efficiency enhancement, fertilizer input reduction, and agricultural greenhouse gas emission mitigation. However, despite substantial evidence from both research and practical applications confirming the benefits of green manure, its large-scale adoption faces numerous challenges, including regional variability in application effectiveness, low farmer acceptance, and insufficient extension technologies. Future research should further clarify the synergistic mechanism between green manure and agronomic measures such as intercropping, crop rotation, conservation tillage, reduced fertilization and organic material return to field. This will help explore the role of green manure in addressing the challenges of soil degradation, climate change and food security, develop green manure varieties adapted to different ecological conditions, and optimize green manure planting and management technologies. Governments should comprehensively promote the implementation of green manure technologies through economic incentives, technology extension, and educational training programs. The integration of scientific research, policy support, and technological innovation is expected to establish green manure as a crucial driving force for facilitating the global transition towards sustainable agriculture. Full article

Foodborne diseases are a growing public health problem worldwide, and chemical foodborne disease outbreaks (FBDOs) often have serious consequences. This study aimed to explore the epidemiological characteristics of chemical FBDOs in Zhejiang Province, China, and propose targeted prevention and control measures. Descriptive statistical methods were used to analyze chemical FBDO data collected from the Foodborne Disease Outbreaks Surveillance System in Zhejiang Province from 2011 to 2023. From 2011 to 2023, 74 chemical FBDOs were reported in Zhejiang Province, resulting in 461 cases, 209 hospitalizations, and one death. In contrast to other types of FBDOs, the percentage of hospitalized cases in chemical FBDOs was the highest (45.34%) (chi-square = 1047.9, p < 0.001). Outbreaks caused by nitrite accounted for the largest percentage (56.76%), followed by lead (17.57%). Outbreaks caused by nitrite occurred mainly in households (27), followed by restaurants (6), street stalls (5), and work canteens (3). Among all nitrite-related outbreaks, 59.52% (25/42) were caused by cooking food where it was used as a common seasoning, 26.19% (11/42) by eating pickled vegetables, 7.14% (3/42) by eating cooked meat products, and 4.76% (2/42) by eating grain products. Outbreaks caused by the misuse of nitrite in cooking mainly occurred in households (68%, 17/25), street stalls (16%, 4/25), work canteens (8%, 2/25), and restaurants (8%, 2/25). Outbreaks caused by eating pickled vegetables occurred mainly in households (90.91%, 10/11), and one outbreak occurred in a work canteen. Outbreaks caused by lead (n = 13) occurred in households, and liquor was involved in 12 outbreaks where they were caused by residents consuming yellow rice wine stored in tin pots. In view of the frequent outbreaks of chemical foodborne diseases in our province from 2011 to 2023, a variety of prevention and control measures were proposed based on the research results of the temporal and regional distribution, food and food establishments involved, and the etiological agents of the chemical FBDOs. However, the effectiveness of these recommendations needs to be further verified and studied. In general, public health institutions should further strengthen the surveillance and health education of the population. Individuals should store toxic chemicals, such as nitrates, pesticides, and rodenticides correctly to avoid poisoning by ingestion. In view of the chemical FBDOs caused by food in the catering and distribution links, relevant departments should strengthen targeted supervision. Full article

This paper investigates a proposal for teaching Green Chemistry concepts through the implementation of a Problem-Based Learning (PBL) approach in a specific and optional course on the subject in higher education. The main objective was to analyze the effect of implementing Problem-Based Learning (PBL) didactics on understanding Green Chemistry principles within a course with 8 university students. Through this methodology, students analyzed case studies involving the identification of GC principles in industrial redesign processes and the problematization of controversial situations related to the importance of discussions on chemical processes. Two specific cases, bio-based butylene glycol and enzymatic treatment of paper, were used to test students’ ability to recognize and justify the relevance of these principles. Additionally, another activity about the synthesis of acetanilide allowed students to identify which of four methodologies could be considered the greenest, considering different aspects. The research revealed that although the PBL approach effectively engaged students and deepened their understanding of GC principles, some concepts presented challenges. Certain principles of Green Chemistry, such as atom economy and catalysis, proved complex for some students, leading to confusion and challenges in assessing the “greenness” of processes. Nonetheless, students demonstrated improved knowledge and practical application of GC principles, linking them to industrial processes like bio-based material production and analyzing the benefits and drawbacks of different methods for producing the same substance. This study highlighted the value of a dedicated PBL approach with adequate resources to foster discussions and understanding. However, elective courses often attract only those already familiar with the subject, limiting broader engagement and field expansion. Disparities in case material quality, particularly for bio-based butylene glycol and acetanilide production, underscored the need for well-structured resources. Future research should include larger sample sizes for statistical validation and more class time for discussions and supplemental activities. This study contributes to the literature on active learning strategies, showcasing PBL’s potential to enhance sustainable chemical education. Full article

The field of additive manufacturing increasingly demands innovative solutions to optimize material processing, improve equipment efficiency, and address maintenance challenges in high-utilization environments. This study investigates the operation and management of an FFF 3D printing production line comprising eight remotely controlled printers. The system supports custom manufacturing and educational activities, focusing on processing a range of thermoplastics and composite materials. A key contribution of this work lies in addressing the impact of frequent hardware servicing caused by shared use among users. Augmented reality (AR)-guided assembly and disassembly workflows were developed to ensure uninterrupted operations. These workflows are accessible via smart devices and provide step-by-step guidance tailored to specific material and equipment requirements. The research evaluates the effectiveness of AR-enhanced maintenance in minimizing downtime, extending equipment lifespans, and ensuring consistent material performance during manufacturing processes. Furthermore, it explores the role of AR in maintaining the mechanical, thermal, and chemical properties of processed materials, ensuring high-quality outputs across diverse applications. This paper highlights the integration of advanced material processing methodologies with emerging technologies like AR, aligning with the focus on enhancing manufacturing schemes. The findings contribute to improving process efficiency and adaptability in additive manufacturing, offering insights into scalable solutions for remote-controlled and multi-user production systems. Full article

Background and Objectives: Traction alopecia is a common type of hair loss that primarily results from prolonged tension in hair follicles. This condition is often associated with certain hairstyles and hair care practices that are prevalent in various cultures, especially in Africa. There have been few studies on this issue in Africa, and none have been conducted in Sudan. Therefore, we aimed to examine the prevalence and associated factors of traction alopecia in women in north Sudan. Materials and Methods: A community-based, cross-sectional study was conducted in north Sudan in December 2022. Women’s sociodemographic characteristics were assessed using a questionnaire, and hair and scalp examinations were performed. A multivariate binary analysis was performed. Results: A total of 192 women participated in the study, and 48 (25.0%) had traction alopecia. The median age of the women was 42.0 years (interquartile range: 32.0–52.0 years). In a multivariate binary analysis, a family history of women with male pattern baldness or thinning (adjusted odds ratio [AOR] = 2.96, 95% confidence interval [CI] = 1.05–8.37) and the use of hair color or chemicals (AOR = 2.98, 95% CI = 1.30–6.83) were positively associated with traction alopecia. In contrast, increasing age was inversely associated with traction alopecia (AOR = 0.96, 95% CI = 0.93–0.99). The women with traction alopecia showed characteristics such as hair breakage, hair loss with the root attached, scalp tenderness, and trichodynia. Conclusions: In north Sudan, one in four women is affected by traction alopecia. Increasing awareness of this condition, providing education on proper hair care methods, and conducting large-scale research are essential steps to prevent its occurrence. Full article