Search Results (454)

The mystical poetry of St. John of the Cross (born in 1542 in Spain and died in 1591), a collaborator of St. Teresa of Jesus in the reform of the Carmelite Order, reveals how the experience of God is indissolubly linked with compassion, and the practice of charity and hope. His life consistently reflects the virtues and attitudes celebrated in his poetry. This paper reinterprets three of his poems—Ascent of Mount Carmel, Of Falconry, and Spiritual Canticle—with a focus on the virtue and attitude of hope. It explores how hope is promoted and expressed through the lens of an ethics shaped by uncertainty and ambiguity, establishing a creative dialogue between classical and disruptive contemporary visions of Sanjuanist ethics. The text proposes an intersection of theology and ethics within a context of vulnerability, complexity, change, volatility, uncertainty, and ambiguity. It also addresses cases of spiritual abuse that distort the mystical and monastic meanings of the “dark night” metaphor. The experience of John of the Cross during his imprisonment is examined in relation to criteria for spiritual growth, with the aim of preventing spiritual misguidance. The paper aims to open the conversation in relation to the problem of abuse and its relation of how the cross may be understood and―in consequence―to help prevent the spiritual abuse that can take place through spiritual guidance. Full article

This article undertakes a cross-cultural comparative inquiry into the motif of “women’s weaving” in medieval Daoism and Christianity. Although the two traditions developed with minimal historical contact, both elevate women’s textile labor into a central metaphor for cosmogenesis, sacred order, and individual salvation. Nevertheless, their hermeneutic trajectories diverge in essential ways. Working within a tripartite analytical framework (intellectual roots, artistic images, ritual practices) to argue that Daoism interprets “women’s weaving” as a proactive technique of transformation and nurture, based on a cosmology of immanent huasheng lun. In this reading, the image is affiliated with the cosmic creativity of nüxian, the inner transformation of their body, and the autonomous pursuit of transcendence. By contrast, within Christianity’s transcendent theological horizon of creatio ex nihilo, “women’s weaving” is configured primarily as an ethical discipline of responsive obedience, closely tied to the mystery of the Incarnation, the imitatio Dei, and communal spiritual exercises and charity under monasticism. The cross-cultural resonance of this motif, I contend, is grounded in the “men’s ploughing and women’s weaving” economic formation, patriarchal gender order, and shared symbolic cognition; its decisive bifurcation arises from contrasting deep cultural structures—namely, cosmology, conceptions of the body, soteriology, and church–state arrangements. Through this micro-case, the article further argues that the sacralization of secular gender roles constitutes an agentic cultural choice, one that indexes distinct civilizational pathways in understanding creation, nature, the body, and freedom. Full article

Background/Objectives: Obesity is a common comorbidity but there remains limited understanding on how higher obesity rates in rural areas may impact physical function decline and other health domains among cancer patients. This study addresses this gap by examining the association between body mass index (BMI) and physical function among a cohort of rural advanced cancer patients. Methods: This cross-sectional analysis uses baseline data from the Nurse AMIE trial (NCT04673019). Individuals were categorized as ‘normal weight’ (BMI ≤ 25 kg/m²), ‘overweight’ (BMI > 25 to 30 kg/m²), and ‘obese’ (BMI > 30 kg/m²). Objective physical function was measured by the Short Physical Performance Battery (SPPB) and subjective physical function and health domains were measured using surveys (PROMIS; SF-36). Results: Of 348 patients included, 88 (25.3%) were classified as ‘normal weight’, 107 (30.7%) as ‘overweight’, and 153 (44.0%) as ‘obese’. Average age was 64.8 years (SD = 12.2), 46% (n = 160) were female, 95% were white (n = 331), and 52% (n = 182) were Stage 4. Total SPPB scores revealed poorer functioning with higher BMI (M ± SD: BMI ≤ 25 kg/m²: 9.1 ± 2.3; BMI > 25–30 kg/m²: 8.3 ± 3.1; BMI > 30 kg/m²: 8.1 ± 2.8; p = 0.04). Similarly, scores from the SF-36 revealed subjective physical function was lower with higher BMI (BMI ≤ 25 kg/m²: 57.9 ± 29.1; BMI > 25–30 kg/m²: 53.7 ± 28.0; BMI > 30 kg/m²: 47.6 ± 27.6; p = 0.004). Participants reported lower levels of energy and greater fatigue with higher BMI (BMI ≤ 25 kg/m²: 49.8 ± 26.1; BMI > 25–30 kg/m²: 45.1 ± 24.6; BMI > 30 kg/m²: 40.7 ± 22.6; p = 0.01). Conclusions: Higher BMI is associated with poorer physical function and increased fatigue among rural advanced cancer patients, highlighting the need for supportive care related to physical function in this at-risk group. Full article

The history of women’s education in Portugal predates the implementation of an official system, which was only consistently addressed after 1836 with Passos Manuel’s reform of primary instruction. Long before that, particularly from the Early Modern period onwards, women religious played a key role in providing education. Convents and Third Order houses—alongside families, charities, and religion-inspired foundations—offered instruction considered appropriate to women’s gender and social status. The Council of Trent (1545–1563) extended strict enclosure to all female convents, leading to the “monasticisation” of education—an arrangement that neither promoted the visibility of female learners nor encouraged the development of the pedagogical models that shaped their instruction. The later emergence of teaching orders, despite their adherence to enclosure, began to challenge the traditional monastic model. Drawing on largely unpublished or scarcely explored archival sources, this article seeks to shed light on the historical reasons behind the prominent and precedent-setting role of monasticism in the field of female education, and to address the enduring invisibility that still shrouds the cloistered world. Full article

This paper studies the influence of moral emotions and beliefs on understanding charitable giving. While specific moral emotions such as empathy, guilt, and shame have been associated with prosocial behavior, how they impact giving behavior may depend on beliefs about the giving of others. Using a laboratory experiment, individuals participated in a dictator game with charity and completed measures of beliefs, empathy, guilt, and shame. Results show that while individual variation in empathy, guilt, and shame is important in explaining charitable giving, these effects depend crucially on individual beliefs. Full article

This study investigates the valorisation of piscindustrial by-products, specifically fishbones from mackerel, horse-mackerel, and sardines, as sustainable sources of multi-mineral ingredients (MMIs) for future dietary supplementation. Ground fishbone powders were first analysed for moisture content and total ash to establish baseline composition. Following these preliminary assessments, the samples underwent mineral profiling using microwave plasma atomic emission spectroscopy (MP-AES), enabling quantification of calcium, phosphorus, magnesium, iron, zinc, sodium, potassium, copper, lead, cadmium, selenium, chromium, tin, manganese, and mercury. All three species yielded high concentrations of essential minerals, supporting their relevance as upcycled nutritional resources. A sardine-based capsule formulation was developed and compared with a commercial calcium supplement through 240 min dissolution testing. While calcium release values differed significantly from 75 min onward, both formulations exhibited similar dissolution profile shapes, despite differing dosage forms. Statistical analysis confirmed time- and formulation-dependent effects, with the sardine capsule demonstrating enhanced calcium bioaccessibility in later phases (95.26 ± 10.11 vs. 78.79 ± 5.39 mg). This work contributes to the advancement of the United Nations Sustainable Development Goals (SDGs), particularly SDG 3, SDG 12, and SDG 14. By transforming marine waste into health-promoting ingredients, and enabling revenue streams for ocean-cleaning charities, this initiative exemplifies circular innovation at the interface of nutrition, sustainability, and marine stewardship. Full article

As AI chatbots are increasingly used in digital fundraising, it remains unclear which communication strategies are more effective in enhancing consumer trust and donation behavior. Drawing on construal level theory and adopting a human-AI interaction perspective, this research examines how message framing in AI-mediated persuasive communication shapes trust and donation willingness. Across four studies, we find that when AI chatbots employ high-level construal (abstract) message framing, consumers perceive the information as less credible compared to when the same message is delivered by a human agent. This reduced message credibility weakens trust in the charitable organization through a trust transfer mechanism, ultimately lowering donation intention. Conversely, low-level construal (concrete) framing enhances both trust and donation willingness. Moreover, the negative impact of abstract message framing by AI chatbots is significantly attenuated when the chatbot features anthropomorphic visual cues, which increase perceived credibility and restore trust and donation willingness. These findings reveal potential risks in deploying AI chatbots for interactive fundraising marketing and offer practical insights for nonprofit organizations seeking to leverage AI in donor engagement. Full article

Preclinical data suggest that cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) modulate inflammatory pathways (e.g., NLRP3, NF-κB, and PPAR-γ), but clinical translation into consistent changes in circulating biomarkers remains ambiguous. Two reviewers independently screened the studies, extracted data, and assessed risk of bias with RoB-2. Random-effects meta-analyses (RevMan 5.4.1) formed standardized mean differences (SMD) or mean differences (MD) as appropriate. The certainty of evidence was graded by means of GRADE. Thirteen studies satisfied inclusion criteria; meta-analyses were feasible for IL-6 (four studies, n ≈ 129 per arm), IL-8 (two studies, n ≈ 78 per arm), IL-10 (two studies, n ≈ 92 per arm), and TNF-α (three studies, n ≈ 105 per arm). Pooled estimates favored CBD but were trivial and imprecise: IL-6 SMD −0.17 (95% CI −0.56 to 0.23; p = 0.41; I² = 55%); IL-8 SMD −0.30 (95% CI −0.62 to 0.01; p = 0.06; I² = 0%); IL-10 SMD −0.10 (95% CI −0.83 to 0.63; p = 0.79; I² = 81%); and TNF-α SMD −0.09 (95% CI −0.45 to 0.27; p = 0.62; I² = 33%). Individual trials reported reductions in biomarkers in high-exposure or diseased populations. GRADE ratings were as follows: IL-6 very low, IL-8 moderate, IL-10 low, and TNF-α moderate. Current RCT evidence demonstrates inconsistent, often trivial effects of phytocannabinoid interventions on circulating inflammatory biomarkers. Full article

The study examines refugees’ experiences in South Africa to understand how they perceive the country’s hospitality and the Ubuntu (“I am because you are”) principle that underpins its asylum framework. The study is relevant in light of refugee demonstrations demanding UNHCR resettlement to other countries. Grounded in the Critical Refugee Studies Collective, it employs a literature-based meta-analysis to explore how refugees interpret and respond to South Africa’s asylum environment. The findings show that while many refugees initially view South Africa as a place of safety, humanitarian practices that position them as dependent and passive recipients of aid can erode their sense of dignity and belonging. This tension has led some refugees to protest for recognition, improved living conditions, and respect for their rights. The paper argues that refugees’ perceptions of the South African state are shaped by their livability, meaning the quality and security of their lives within the host country. Those who experience relative stability express a stronger sense of acceptance, whereas those facing exclusion, poverty, or xenophobic violence often express dissatisfaction. The study concludes that improving structural conditions and promoting a rights-based rather than charity-based approach would enhance a more dignified environment for refugees in South Africa. Full article

(1) Background: Medication shortages have become increasingly common in the UK. However, there is limited evidence regarding the experiences of people with epilepsy and their caregivers during these shortages. The aim of this study is to explore the extent and impact of ASM shortages on people with epilepsy and their caregivers across the UK. (2) Methods: A cross-sectional online survey was distributed between January and April, 2024 by epilepsy charities. Participants included people with epilepsy and caregivers. The survey collected demographic information, types of ASM respondents were prescribed, experiences of shortages, and the impact of shortages. Data were analysed descriptively, and subgroup analyses were conducted by medication type. (3) Results: A total of 1549 responded, of whom 1312 were people with epilepsy and their carers who were included in the analysis with a mean age of 43 years. A total of 941 respondents (71.7%) reported difficulty obtaining their prescribed ASM in the past year. Shortages were most frequently reported for sodium valproate (60.8%), lamotrigine (65.2%), carbamazepine (92.6%), clobazam (82.6%), topiramate (81.5%), zonisamide (74.0%), levetiracetam (62.8%), lacosamide (71.0%), and brivaracetam (70.5%). A total of 529 (40.4%) of the participants reported that stress and/or anxiety caused by medication shortages was associated with recurrent seizures. We did not ask whether patients missed medications because of these difficulties. (4) Conclusions: ASM shortages are a widespread issue for people with epilepsy in the UK, leading to treatment disruptions and psychological distress. Addressing supply change limitations and identifying effective approaches to preventing the substitution of ASMs brands by clinicians may potentially reduce this problem. Full article

This article commences from a transdisciplinary research setting where students, artists, activists, and researchers come together to investigate medieval travelling accounts. The article is structured in two main parts. The first part presents an exploration of the theoretical framework of an hermeneutics of charity and suspicion as well as a development of a methodology that probes at the “cracks” of colonial pedagogical and scholarly structures. In the second part, the article uses critical inquiry and shared learning experiences to examine Marco Polo’s The Travels, focusing on his descriptions of dancing. Specifically, it investigates what Polo’s text conveyed—and omitted—about the relationship between intimacy, eroticism, and dance for a European audience. Combining auto-ethnographic reflections with stories from the communal learning process, the article invites readers to consider how collective inquiry reshapes our understanding of historical texts. In addition to questioning Polo/Rustichello’s portrayal of religious dance through his mercantile and sexualised gaze, the author also challenges some previous scholarly interpretations of Polo as an agent of European colonial endeavours. Finally, the paper offers a method for rethinking how researchers approach dance and university education, as well as practical tools for how historical accounts can be explored in a way that prevents discernment from overshadowing what can be gained from attunement. Full article

The Nationality and Borders Act 2022 was enacted despite significant opposition from refugee charity and legal sectors. It is without question that the Act changes the domestic landscape of the refugee status determination system and has the potential to also negatively influence refugee status determinations in other jurisdictions. There are several sections of the Act that are particularly problematic for women’s claims of asylum. The Act reverses well-established international and regional human rights and refugee law principles and standards. The reversal, in some cases, of decades of jurisprudence on the interpretation of the Refugee Convention poses a concern for the integrity of the law and administrative justice. While the Act imposes barriers for all claimants, it disproportionately affects some of the most complex cases, including refugee women fleeing gender-based persecution. Of the various changes brought about by the Act, this article focuses on three that are particularly relevant to women asylum seekers: first, the regressive way in which membership of a particular social group has been framed; second, the heightened standard of proof now required; and third, the associated evidential burdens in relation to trauma and disclosure. Ultimately, these changes are likely to have a disproportionate and discriminatory impact on women seeking asylum, particularly those fleeing gender-based persecution. Full article

Patients on hemodialysis (HD) often experience changes in body composition due to metabolic disorders. Phase angle (PhA) is a marker of tissue integrity and may reflect overall functional condition. This study evaluated body composition and its relationship with PhA in 53 HD patients (27 women, 26 men) over 40 years old, compared with 106 age- and sex-matched healthy controls. Body composition was assessed using bioelectrical impedance analysis (BIA), measuring skeletal muscle mass (SMM), fat tissue, total bone mass (BM), and PhA. HD patients had significantly lower fat mass and PhA than controls (p < 0.001). The prevalence of low SMM and BM was higher in patients, though not statistically significant. Sex differences were generally not significant, except for a higher prevalence of low BM in female controls (p < 0.001). After adjusting for age and sex, PhA was positively associated with SMM% (p = 0.021) and BM (p = 0.035) in HD patients only. These results indicate that PhA–body composition relationships differ between HD patients and healthy individuals, highlighting PhA as a potential marker of body composition disturbances in HD. Full article

Charitable giving plays a vital role in advancing sustainable development, yet little is known about its determinants in transitional economies. This study addresses this gap by examining the socioeconomic and psychological drivers of prosocial financial behavior in Uzbekistan, integrating the Theory of Planned Behavior (TPB), Norm Activation Theory (NAT), and Well-Being Theory. Data from a sample of 348 individuals reveal two distinct pathways of giving: one shaped by resources (income, age) and another by subjective well-being (happiness). While income, age, and happiness emerged as significant positive predictors of charitable behavior, traditional TPB factors such as attitude, subjective norms, and perceived behavioral control were not supported in this context. A surprising finding was the negative association between personal norms and charitable giving, challenging assumptions of Western-centric models and pointing to the importance of cultural and institutional conditions, such as trust in charities and informal giving practices. The study contributes to sustainability research by showing that fostering well-being and targeting specific demographic groups can enhance philanthropy, while also emphasizing the need for culturally sensitive approaches in understanding prosocial behavior within emerging economies. Full article

This methodological review identifies challenges in the development of health economic evaluations of newborn bloodspot screening (NBS) interventions and their consideration in NBS policy making. A systematic review of health economics methodological studies in NBS and stakeholder consultation was undertaken. The intervention under examination was defined as health economic decision analytic modelling used as decision support to NBS policy makers. An iterative search strategy was used to identify studies, and a data extraction framework was based upon a simple decision analytic model structure for the NBS decision problem. Synthesis was facilitated by two stakeholder workshops, which focused on ensuring the complete identification of challenges and developing recommendations. Sixteen methodological studies were identified. Data were extracted on challenges in decision criteria, decision variables, decision problem scope, defining model structure, selecting modelling method, the target condition, the screening test/protocol, outcome nodes, and other categories. Recommendations are made concerning supporting NBS decision making, NBS economic model structure and methods, data and estimation of model parameters, and overarching considerations. Recommendations for decision processes and methods research are put forward for the consideration of NBS policy makers and commissioners of research. Full article