Search Results (236)

Phacelia tanacetifolia Benth. is a species of annual plant that has been gaining importance in recent years. Initially, it was treated as an ornamental plant and valuable only to bees. Over the years, this species has become more widely known, and many more of its advantages have been discovered. The aim of this study was to learn about the contemporary economic importance of Phacelia tanacetifolia Benth. The extraordinary, rapid increase in the plant’s biomass means that it is valued as a fodder plant and at the same time is included in the group of leaders among catch crops. It is characterized by low requirements for soil quality. The main advantage of this plant is its high resistance to drought and frost. A great advantage of this plant is its high drought resistance. It is recommended for sowing both in monoculture and in mixtures with other species. In the light of current standards and assumptions, it fits perfectly into the framework of sustainable development. It is a valuable link in the biodiversity chain, as well as support for a number of ecosystem services such as CO₂ sequestration, retention of nutrients in the soil or protection of its structure. Phacelia is seen as having great potential as a plant that provides food for a number of pollinators. The latest research also focuses on assessing the possibility of using it for energy purposes (biogas). Efforts are being made to introduce phacelia on a wider scale to eliminate crop monocultures and significantly strengthen biodiversity in a given area. Phacelia plays an important role in various agronomic systems and effectively supports the protection of the natural environment. The contribution of this species to the development of ecosystem services to date is undeniable. It should be assumed that this plant will continue to significantly support a number of activities for sustainable development. Full article

With the digital economy continuing to integrate deeply into the agricultural sector, agricultural digital transformation has emerged as a pivotal driver of rural revitalization and the development of a robust agricultural economy. Although existing studies have affirmed the positive role of agricultural digital transformation in promoting rural development and enhancing agricultural efficiency, its spatiotemporal evolution patterns, regional disparities, and underlying driving factors have not yet been systematically and thoroughly investigated. This study seeks to fill that gap. Based on provincial panel data from China spanning 2011 to 2023, this study employs the Theil index, kernel density estimation, Moran’s index, and quantile regression to systematically assess the spatiotemporal dynamics and driving factors of agricultural digital transformation at both national and regional levels. The results reveal a steady overall improvement in agricultural digital transformation, yet regional development imbalances remain prominent, with a shift from inter-regional disparities to intra-regional disparities over time. The four major regions exhibit a stratified evolutionary trajectory marked by internal differentiation: the eastern region retains its lead, while central and western regions show potential for catch-up, and the northeastern region faces a “balance trap.” Economic development foundation, human capital quality, and policy environment support are identified as the core driving forces of transformation, while other factors demonstrate pronounced regional and phase-specific variability. This study not only deepens theoretical understanding of the uneven development and driving logic of agricultural digital transformation but also provides empirical evidence to support policy optimization and promote more balanced and sustainable development in the agricultural sector. Full article

High-quality growth of the construction industry and an improved human settlements environment are essential to sustainable urbanization. Existing studies have paid limited systematic attention to the spatial and temporal dynamics of the coordinated development between the construction industry and human settlements, as well as the underlying factors driving regional disparities. This gap restricts the formulation of precise, differentiated sustainable policies tailored to regions at different development stages and with varying resource endowments. Southern China, characterized by pronounced spatial heterogeneity and unique development trends, offers a natural laboratory for examining the spatio-temporal interaction between these two dimensions. Using panel data for 15 southern provinces (2013–2022), we applied the entropy method, coupling coordination model, Dagum Gini coefficient, spatial trend surface analysis, gravity model, and grey forecasting to evaluate current conditions and predict future trends. The main findings are as follows. (1) The coupling coordination degree rose steadily, forming a stepped spatial pattern from the southwest through the center to the southeast. (2) The coupling coordination degree appears obvious polarization effect, presenting a spatial linkage pattern with Jiangsu-Shanghai-Zhejiang, Hubei-Hunan-Jiangxi, and Sichuan-Chongqing as the core of the three major clusters. (3) The overall Dagum Gini coefficient declined, but intra-regional disparities persisted: values were highest in the southeast, moderate in the center, and lowest in the southwest; inter-regional differences dominated the total inequality. (4) Forecasts for 2023–2027 suggest further improvement in the coupling coordination degree, yet spatial divergence will widen, creating a configuration of “eastern leadership, central catch-up acceleration, and differentiated southwestern development.” This study provides an evidence base for policies that foster high-quality construction sector growth and enhance the living environment. The findings of this study indicate that policymaking should prioritize promoting synergistic regional development, enhancing the radiating and driving role of core regions, and establishing a multi-level coordinated governance mechanism to bridge regional disparities and foster more balanced and sustainable development. Full article

We have previously shown a difference between the gut microbiota composition of stunted and non-stunted children in East Nusa Tenggara, Indonesia. The current study aimed to perform an intervention with a probiotic, Lactiplantibacillus plantarum IS-10506, and its UHT-treated postbiotic compared to placebo in order to accomplish catch-up growth in the stunted children, possibly through modulation of the gut microbiota. Apart from the maltodextrin (placebo), probiotic, and postbiotic in chocolate milk, all groups also received a functional and nutritional biscuit and had access to newly constructed water wells as well as soap to improve hygiene. The results show that independent of treatment, the stunted children had a significantly higher increase in height and zlen (corrected for age) compared with their age- and gender-matched controls but a significantly lower increase in weight. Several potential pathogenic taxa declined in all groups, among which was Escherichia/Shigella (adjusted.p = 6.44 × 10⁻¹⁵), but so did some beneficial taxa, such as Bifidobacterium and Akkermansia. Faecalibacterium, which was already higher in the stunted children at baseline, increased independent of treatment. Changes in the relative abundance of several taxa of the microbiota correlated with the changes in anthropometric measures. In conclusion, although there was no difference between the interventions, understanding the dynamics and the role of the gut microbiota in this process might allow healthcare providers to develop targeted nutritional strategies aimed at optimizing health outcomes for children at risk of stunting, thereby addressing a critical global health issue. Full article

Measurements play a specific role in quantum mechanics; only measurements allow us to catch a glimpse of the eluding physical reality. However, there is something deeply unsatisfactory with this specificity—a measurement is itself a physical process! Several varying modes of coping with this dilemma have been proposed and this article tries to describe how a now-century-long discussion has led to new insights about the transition from the quantum to the classical world. Starting from the pioneer’s view of the quantum measurement problem, it follows the development of formalisms, the interest from philosophers for its new aspects on reality and how different interpretations of quantum mechanics have tried to support our classically working brains in understanding quantum phenomena. Decoherence is a main topic and its role in measurement processes exemplified. The question of whether the quantum measurement problem is now solved is left open for the readers’ own judgment. Full article

The aim of this research was to clarify the concept of vulnerable micro-enterprises (MEs) and develop a set of indicators for identifying and analyzing developments in vulnerable MEs in “catching up” economies in the context of the regulation on the Social Climate Fund (SCF). The case of Lithuania is studied. A retrospective analysis of business structure research indicators during the period from 2010 to 2023 was carried out. The method of the median was applied to determine thresholds of indicators above (below) which a ME is considered vulnerable. Absolute and relative business structure research indicators were calculated to provide estimates of the number of vulnerable MEs and reveal their role in the economy. The results revealed the number and share of vulnerable MEs which experienced high fuel expenditure (above the median (1M), 1.5M, or 2M). Historically, these MEs created a share of added value and provided employment opportunities. The share was found to vary in accordance with economic activity and the Lithuanian municipality, suggesting that the distribution of financing from the SCF should consider aspects of economic activity and regionality. A number of MEs had an essential share of fuel expenditure in their total operating costs. Vulnerable MEs demonstrate low or negative profitability, and may be insolvent; therefore, they cannot invest in building renovation or environmentally friendly transport. Thus, the research results indicate the need for discussions regarding financing vulnerable MEs in Lithuania. Full article

Monitoring changes in fishery resources, such as the density and growth of fish, following large-scale fish stocking in a reservoir is important. In this study, BioSonics DT-X (201 kHz) was used to assess the seasonal changes in the density, size distribution, and biomass of fish in Duihekou Reservoir, Zhejiang province, China, in 2020. The fish density was significantly lower in spring (3.33 ind./1000 m³) than in summer (75.24 ind./1000 m³), autumn (56.22 ind./1000 m³), and winter (20.37 ind./1000 m³) (p < 0.01). No significant difference in fish density was apparent between summer and autumn. Additionally, the average target strength (TS) values in spring (−41.05 dB) were significantly higher than in summer (−44.66 dB) and autumn (−45.55 dB) (p < 0.01), but significantly higher in winter (−38.12 dB) than in the other seasons (p < 0.01); no significant difference was observed between the summer and autumn values (p > 0.01). The fish biomass in winter (14.3 g/m³) was 13 times that in spring (1.1 g/m³). These results indicate that large-scale fish stocking can effectively adapt to reservoir habitats to achieve growth. The catch composition revealed silver carp (Hypophthalmichthys molitrix) and bighead carp (Aristichthys nobilis) to be dominant species, mostly comprising young individuals. Stock enhancement plays a critical role in reshaping the fishery population structure in a reservoir. These findings enhance our understanding of fishery resource changes in reservoirs after non-classical biomanipulation and demonstrate how hydroacoustic techniques can be successfully used to quantify the density and size distribution of fish for more effective fishery management. Full article

Small-scale inshore fisheries significantly contribute to the total landing volumes and have an important role in Vietnamese socioeconomic development, food security, livelihoods, and social well-being. The setnet fishery has been used throughout coastal communities of Vietnam for many decades. Being a passive fishing gear, the catch efficiency of setnet depends on various conditions such as fish density, season, oceanography, environment, and others. However, very little information exists about the relationship between catch rates and national conditions. Recognizing this research gap, this study examined the effect of temporal and environmental conditions on the catch rates of the narrow-barred Spanish mackerel (Scomberomorus commerson) setnet fishery using long-term data from 2005 to 2016. Overall, the catch of narrow-barred Spanish mackerel decreased over the course of the study. The generalized additive model (GAM) showed that catch rates were significantly affected by sea surface temperature (SST), which peaked at 27 °C. After this temperature point, the catch rates significantly decreased. Temporal variables also contributed to the catch variation. The setnet caught the highest yield in April and May, and more fish were caught during periods of low nightlight intensity than during high illuminated periods. Our study contributes to the understanding of critical factors affecting the catch rates of valuable species, which helps to determine the optimal fishing process of the setnet fishery within the shifting of marine heatwaves. Full article

Wine markets have deeply changed in recent decades in many regards. In particular, wine trade patterns have been deeply reshaped, and this also affects traditional EU exporters, who operate in a more competitive environment, with new players challenging their position and forcing them to readjust their strategies. This study analyzes recent trends in the wine exports of major EU producers. Its goal is to contribute to assessing to what extent their positioning in the international wine markets differs, and to understand the kind of competition they engage in within destination markets, with a focus on the role of their export quality as a major competitive advantage. This analysis only looks at bottled wines, both still and sparkling. It combines the use of traditional trade indicators—such as export quotas, penetration rates, and the average unit value of exports (AUV) with an innovative indicator, called C-Consy, aimed at measuring the sophistication levels of the destination markets. The results show that EU competitors behave in different ways and move along different paths. Some of them show an increasing ability to sell their products in higher segments of sophisticated markets. Others are also quite well positioned in the global arena, but they are fighting to fully catch up with the increasing demand for more sophisticated products from their clients. Some have managed to improve quality and hence advance to higher market segments, while others have shown greater weakness in facing global competition. Looking at typologies, exporters do not always show the same positioning and trends for still and sparkling wines. Full article

Background: Given the significant impact of population immunity on the measles epidemic, understanding immunity differences among populations with varying immunity backgrounds is necessary for identifying immunity gaps and informing vaccination policies. In this study, we aimed to determine the distinct dynamics of vaccine-induced and naturally acquired antibodies, with specific focus on difference in vaccine-induced antibody responses across different birth cohorts. Methods: Based on two cohorts and one cross-sectional study conducted in Anhua County, Hunan Province, China, serum samples from children who followed China’s routine measles vaccination schedule (i.e., two-dose schedule at 8/18 months) and adults who acquired immunity through natural infection were tested for measles IgG antibodies using an enzyme-linked immunosorbent assay. The generalized additive mixed model and a mechanistic model were employed to describe antibody dynamics following vaccination and infections. Wavelet analysis was used to investigate the temporal relationship between the measles epidemic and long-term antibody levels after natural infection. Results: A total of 408 children (0–12 years) and 222 adults (54–84 years) were included in the present study. Vaccine-induced antibody levels following 8 m/18 m vaccination were estimated to fall below the protective threshold of 200 mIU/mL by age of 15.8, whereas antibody levels following infections remained high. The decay rate of vaccine-induced antibodies was estimated at 3.0 × 10⁻³ log-log mIU/mL per year, whereas naturally acquired measles antibodies persisted lifelong with a significantly lower decay rate of 2.30 × 10⁻⁵ log-log mIU/mL per year. Moreover, vaccine-induced antibody levels in children born after 2010—a period of low measles incidence—declined more rapidly (duration of protective immunity: 12.5 years), compared to those born before 2010. Discussion: Our findings revealed immunity heterogeneity among individuals with difference measles immunity backgrounds. In particular, the birth-cohort specific differences in vaccine-induced immunity highlighted the key role of young generations born in settings with low measles incidence in contributing to population immunity gaps. This underlines that greater attention should be given to this group in future catch-up vaccination efforts. Full article

Carbon lock-in (CLI), defined as the structural persistence of fossil-fuel-based systems, poses a significant barrier to decarbonization. As CLI continues to impede China’s progress toward carbon neutrality, understanding the role of next-generation productive forces (NGPFs) in breaking this path dependence has become increasingly urgent; however, it remains underexplored in empirical research. This study examines the impact of NGPFs on CLI using provincial panel data from 2012 to 2022. Composite indices for NGPFs and CLI are constructed using the entropy weight method. The analysis applies instrumental variable estimation (IV-GMM) to address potential endogeneity, feasible generalized least squares (FGLS) to account for heteroskedasticity, and spatial Durbin models (SDMs) to capture spatial dependence. In addition, quantile regression is used to explore distributional effects, and subsample regressions are conducted to assess regional heterogeneity. The results show that (1) a 1% increase in NGPFs leads to approximately a 0.9643% reduction in CLI, effectively mitigating CLI. (2) NGPF levels are high in Beijing, Shanghai, and Guangdong, while being constrained in Heilongjiang, Gansu, and Qinghai. Provinces like Jiangsu, Zhejiang, and Shandong are rapidly catching up. (3) Shanxi, Inner Mongolia, and Shandong struggle with high comprehensive CLI from carbon-heavy industries; in contrast, Beijing, Shanghai, and Hainan show low CLI. (4) As CLI levels increase (90th percentile), the effectiveness of NGPFs in reducing CLI gradually diminishes (−0.2724). (5) The impact of NGPFs on CLI is not significant in the Eastern region, while in the Central and Western regions, the effects are −1.1365 and −1.0137, respectively. This study offers vital insights for shaping policies that promote sustainable growth and mitigate CLI in China. Full article

The invasive spotted wing Drosophila (SWD) represents new challenges for European and North American fruit producers. The aim of our study was to examine wine grape cultivar susceptibility to this pest and melanogaster-type Drosophila (MTD) by surveying drosophilid populations using field traps and conducting emergence tests. We assessed fly development from intact and artificially injured berries collected from four cultivars. Berries were incubated individually and in pooled samples to evaluate infestation patterns and potential larval interactions. Although grapes are generally considered less favorable hosts for SWD, the pest was consistently present across all vineyard plots. Infestation levels differed significantly among cultivars, with the Hungarian white cultivar Furmint being the most susceptible, while French-origin red cultivars Cabernet Franc and Cabernet Sauvignon, along with the other Hungarian cultivar Rózsakő, were less susceptible. Berry integrity played a crucial role: intact berries showed minimal infestation, whereas physical injuries led to a substantial and significant increase in infestation rates and fly emergence. In contrast to SWD-dominated trap catches and the nearly equal proportions of SWD and MTD observed in intact berries, injured berries were predominantly colonized by MTD. This dominance became even more pronounced in pooled samples, suggesting that larval competition in shared environments favors MTD over SWD. These findings underscore the importance of grape cultivar traits and berry condition in shaping Drosophila infestation dynamics. Further research into the chemical and ecological drivers of host selection and interspecific interactions is warranted to improve vineyard pest management strategies. Full article

Research increasingly highlights jellyfish as a sustainable alternative to other animal species, particularly for its collagen, which has versatile applications in blue biotechnology. This review explores the properties of jellyfish-derived collagen, extraction techniques, and its diverse industrial applications based on the current scientific literature. With a particular focus on research in the Mediterranean Sea, we underscore the role of the order Rhizostomeae as jellyfish species with high collagen content and provide an overview of the main sources for jellyfish harvesting, including active fishing, by-catch, and aquaculture. In the Mediterranean basin, the blooming species Rhizostoma pulmo, Cotylorhiza tuberculata, and Rhopilema nomadica represent a valuable opportunity to harness their nutraceutical benefits, as well as their potential for the development of biomaterials in tissue engineering and regenerative medicine. Although jellyfish fishing is not yet well-established in the region, ongoing collaborative projects with fishermen’s guilds are focused on promoting circular and blue economy strategies to valorize jellyfish as an innovative resource. Additionally, jellyfish aquaculture emerges as a promising alternative for ensuring a sustainable supply, with the Rhizostomeae Cassiopea spp. demonstrating significant potential for biotechnological applications. Full article

This study investigates how the digital economy empowers urban network intensity to address the dilemma of “low-efficiency lock-in” and to promote high-quality and balanced innovation development. Based on panel data from 264 prefecture-level and above cities in China from 2011 to 2022, the study adopts a multi-network perspective—covering innovation, information, and economic networks—and employs fixed effects and two-stage models to examine the impact and underlying mechanisms of the digital economy on disparities in urban innovation efficiency. The results reveal that the digital economy significantly reduces the gap in innovation efficiency across cities, primarily through the optimization of innovation networks and the strengthening of information networks. Moreover, the economic network positively moderates this relationship, amplifying the digital economy’s narrowing effect on innovation disparities. Threshold model tests indicate a nonlinear influence of the digital economy, showing an initial widening followed by a reduction in innovation efficiency gaps as innovation, information, and economic networks evolve. Heterogeneity analysis suggests that among the various dimensions of the digital economy, only digital industrialization plays a significant role in reducing efficiency disparities, while digital governance, digital infrastructure, industrial digitalization, and data valorization do not yet show statistically significant effects. Furthermore, the digital economy significantly reduces innovation efficiency gaps in southern cities, in regions southeast of the Hu Line, and in large cities, whereas in cities northwest of the Hu Line, digital economy development tends to exacerbate these disparities. This study provides both theoretical support for the coordinated improvement of innovation efficiency driven by the digital economy and practical implications for lagging cities aiming to leverage network effects to catch up in innovation performance. Full article

ESS2 (ess-2 splicing factor homolog, also known as DGCR14 or DGS-I) is a member of the deletion gene cluster in the 22q11.2 deletion syndrome (22q11.2DS, also known as DiGeorge syndrome or CATCH 22 syndrome). The ESS2 gene is not part of a gene family, and the coded protein has a coiled-coil structure (Es domain), which is conserved from yeast to humans. Recent studies have shown that ESS2 is involved in splicing C and C* complex, but other interactants, such as transcription factors and U1 snRNP, are also reported. Although the molecular mechanism is still under investigation, ESS2 plays a pivotal role in cell differentiation and proliferation. ESS2 knockout mice show embryonic lethal in the early stage, and recent studies show the association of ESS2 with cancer, autoimmune disease, and neurodevelopmental disorders. ESS2 can regulate mRNA splicing and transcriptional activity through interactions with other proteins, and ESS2-dependent gene expression regulation seems to be cell type-selective. In this review, we summarized the cloning history and functions of ESS2, including recent findings. Full article