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Search Results (985)

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15 pages, 2758 KB  
Article
First-Principles Calculation of the Desolvation Effect of Functionalized Carbon Nanotubes
by Fudong Liu, Sinan Li, Wanjun Zhu, Miaomiao Zhao and Bing Liu
Coatings 2025, 15(10), 1190; https://doi.org/10.3390/coatings15101190 - 10 Oct 2025
Viewed by 244
Abstract
This study used density functional theory (DFT)-based first-principles calculations to investigate the desolvation effect of single-walled carbon nanotubes (SWCNTs) modified with hydroxyl (-OH), carbonyl (-C=O), and carboxyl (-COOH) groups. SWCNTs have great potential as supercapacitor electrode materials due to their unique structural and [...] Read more.
This study used density functional theory (DFT)-based first-principles calculations to investigate the desolvation effect of single-walled carbon nanotubes (SWCNTs) modified with hydroxyl (-OH), carbonyl (-C=O), and carboxyl (-COOH) groups. SWCNTs have great potential as supercapacitor electrode materials due to their unique structural and electronic properties, but their practical application is limited by poor solvation-induced dispersibility and low ion transport efficiency. To solve this, this study constructed functionalized SWCNT models, simulated their interaction with lithium ion (Li+) complexes in acetonitrile (AN) solvent, and analyzed Li+ desolvation behavior, relative capacitance, and post-desolvation density of states (DOSs). The key research results are as follows: [Li(AN)]+ complete desolvation sizes differed: 5.91 Å (pristine SWCNTs), 6.26 Å (hydroxylated SWCNTs, HCNT), 6.11 Å (carbonylated SWCNTs, CNCNT; carboxylated SWCNTs, CXCNT). HCNT showed the largest relative capacitance enhancement (max 1.4× pristine), while CNCNT and CXCNT both had a max 1.3× improvement. Post-desolvation DOS analysis revealed distinct electronic property changes: HCNT-Li+ enhanced metallicity and conductivity; CNCNT-Li+ increased metallicity but reduced conductivity; and CXCNT-Li+ decreased metallicity with nearly unchanged conductivity. This study provides an atomic-scale theoretical basis for optimizing the properties of SWCNT solutions, supporting their application in high-performance supercapacitors, particularly in enhancing device energy density and cycle stability. Full article
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28 pages, 1955 KB  
Article
Comparative Analysis of High-Voltage High-Frequency Pulse Generation Techniques for Pockels Cells
by Edgard Aleinikov and Vaidotas Barzdenas
Appl. Sci. 2025, 15(19), 10830; https://doi.org/10.3390/app151910830 - 9 Oct 2025
Viewed by 348
Abstract
This paper presents a comprehensive comparative analysis of high-voltage, high-frequency pulse generation techniques for Pockels cell drivers. These drivers are critical in electro-optic systems for laser modulation, where nanosecond-scale voltage pulses with amplitudes of several kilovolts are required. The study reviews key design [...] Read more.
This paper presents a comprehensive comparative analysis of high-voltage, high-frequency pulse generation techniques for Pockels cell drivers. These drivers are critical in electro-optic systems for laser modulation, where nanosecond-scale voltage pulses with amplitudes of several kilovolts are required. The study reviews key design challenges, with particular emphasis on thermal management strategies, including air, liquid, solid-state, and phase-change cooling methods. Different high-voltage, high-frequency pulse generation architectures including vacuum tubes, voltage multipliers, Marx generators, Blumlein structures, pulse-forming networks, Tesla transformers, switching-mode power supplies, solid-state switches, and high-voltage operational amplifiers are systematically evaluated with respect to cost, complexity, stability, and their suitability for driving capacitive loads. The analysis highlights hybrid approaches that integrate solid-state switching with modular multipliers or pulse-forming circuits as offering the best balance of efficiency, compactness, and reliability. The findings provide practical guidelines for developing next-generation high-performance Pockels cell drivers optimized for advanced optical and laser applications. Full article
(This article belongs to the Section Electrical, Electronics and Communications Engineering)
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23 pages, 2058 KB  
Article
Inductive Displacement Sensor Operating in an LC Oscillator System Under High Pressure Conditions—Basic Design Principles
by Janusz Nurkowski and Andrzej Nowakowski
Sensors 2025, 25(19), 6078; https://doi.org/10.3390/s25196078 - 2 Oct 2025
Viewed by 384
Abstract
The paper presents some design principles of an inductive displacement transducer for measuring the displacement of rock specimens under high hydrostatic pressure. It consists of a single-layer, coreless solenoid mounted directly onto the specimen and connected to an LC oscillator located outside the [...] Read more.
The paper presents some design principles of an inductive displacement transducer for measuring the displacement of rock specimens under high hydrostatic pressure. It consists of a single-layer, coreless solenoid mounted directly onto the specimen and connected to an LC oscillator located outside the pressure chamber, in which it serves as the inductive component. The specimen’s deformation changes the coil’s length and inductance, thereby altering the oscillator’s resonant frequency. Paired with a reference coil, the system achieves strain resolution of ~100 nm at pressures exceeding 400 MPa. Sensor design challenges include both electrical parameters (inductance and resistance of the sensor, capacitance of the resonant circuit) and mechanical parameters (number and diameter of coil turns, their positional stability, wire diameter). The basic requirement is to achieve stable oscillations (i.e., a high Q-factor of the resonant circuit) while maintaining maximum sensor sensitivity. Miniaturization of the sensor and minimizing the tensile force at its mounting points on the specimen are also essential. Improvement of certain sensor parameters often leads to the degradation of others; therefore, the design requires a compromise depending on the specific measurement conditions. This article presents the mathematical interdependencies among key sensor parameters, facilitating optimized sensor design. Full article
(This article belongs to the Topic AI Sensors and Transducers)
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25 pages, 989 KB  
Article
A Deep Reinforcement Learning Model to Solve the Stochastic Capacitated Vehicle Routing Problem with Service Times and Deadlines
by Sergio Flavio Marroquín-Cano, Elías Neftalí Escobar-Gómez, Eduardo F. Morales, Elizeth Ramírez-Álvarez, Pedro Gasga-García, Eduardo Chandomí-Castellanos, J. Renán Velázquez-González, Julio Alberto Guzmán-Rabasa, José Roberto Bermúdez and Francisco Rodríguez-Sánchez
Mathematics 2025, 13(18), 3050; https://doi.org/10.3390/math13183050 - 22 Sep 2025
Viewed by 999
Abstract
Vehicle Routing Problems are central to logistics and operational research, arising in diverse contexts such as transportation planning, manufacturing systems, and military operations. While Deep Reinforcement Learning has been successfully applied to both deterministic and stochastic variants of Vehicle Routing Problems, existing approaches [...] Read more.
Vehicle Routing Problems are central to logistics and operational research, arising in diverse contexts such as transportation planning, manufacturing systems, and military operations. While Deep Reinforcement Learning has been successfully applied to both deterministic and stochastic variants of Vehicle Routing Problems, existing approaches often neglect critical time-sensitive conditions. This work addresses the Stochastic Capacitated Vehicle Routing Problem with Service Times and Deadlines, a challenging formulation that is suited to model time routing conditions. The proposal, POMO-DC, integrates a novel dynamic context mechanism. At each decision step, this mechanism incorporates the vehicle’s cumulative travel time and delays—features absent in prior models—enabling the policy to adapt to changing conditions and avoid time violations. The model is evaluated on stochastic instances with 20, 30, and 50 customers and benchmarked against Google OR-Tools using multiple metaheuristics. Results show that POMO-DC reduces average delays by up to 88% (from 169.63 to 20.35 min for instances of 30 customers) and 75% (from 4352.43 to 1098.97 min for instances of 50 customers), while maintaining competitive travel times. These outcomes highlight the potential of Deep Reinforcement Learning-based frameworks to learn patterns from stochastic data and effectively manage time uncertainty in Vehicle Routing Problems. Full article
(This article belongs to the Special Issue Stochastic System Analysis and Control)
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13 pages, 1199 KB  
Article
Evaluation of the Effectiveness of TECAR and Vibration Therapy as Methods Supporting Muscle Recovery After Strenuous Eccentric Exercise
by Łukasz Oleksy, Anna Mika, Maciej Daszkiewicz, Martyna Sopa, Miłosz Szczudło, Maciej Kuchciak, Artur Stolarczyk, Olga Adamska, Paweł Reichert, Zofia Dzięcioł-Anikiej and Renata Kielnar
J. Clin. Med. 2025, 14(18), 6648; https://doi.org/10.3390/jcm14186648 - 21 Sep 2025
Viewed by 1664
Abstract
Background/Objectives. Despite growing interest in capacitive-resistive electric transfer TECAR) and Vibration therapy (VT), their comparative effectiveness in sports recovery remains unclear. This study aimed to evaluate and contrast the short-term effects of TECAR and VT on neuromuscular recovery following eccentric muscle fatigue, [...] Read more.
Background/Objectives. Despite growing interest in capacitive-resistive electric transfer TECAR) and Vibration therapy (VT), their comparative effectiveness in sports recovery remains unclear. This study aimed to evaluate and contrast the short-term effects of TECAR and VT on neuromuscular recovery following eccentric muscle fatigue, relative to passive rest, in active young adults. We hypothesized that both interventions would accelerate recovery and potentially reduce injury risk. Methods. Forty-one participants were randomized into two groups: TECAR therapy (Group 1) and VT (Group 2). Neuromuscular function was assessed at baseline, post-exercise, and post-intervention using tensiomyography (TMG) and electromyography (EMG). Results. Both groups showed a significant increase in EMG MDF intercept after exercise. Post-intervention, VT induced a further rise in this parameter, whereas TECAR stabilized values without significant change. In the contralateral resting limb, increases persisted after exercise and passive recovery. Between-limb differences were significant only in the TECAR group. TMG analysis revealed a non-significant but large-effect increase in contraction delay (Td) post-exercise, followed by significant reductions after both interventions. In the left limb, Td changes were not significant. For maximal displacement (Dm), both VMO and VLO muscles demonstrated a significant decrease post-exercise and a marked recovery after both therapies. Other TMG parameters (Ts, Tc, Tr) showed no significant changes. Conclusions. Both TECAR and VT effectively enhanced neuromuscular recovery after eccentric exercise. TECAR demonstrated a modest but consistent advantage, particularly in normalizing muscle recruitment and restoring mechanical properties, making it suitable in contexts requiring rapid recovery. VT, however, remains a more accessible and cost-effective modality. These findings support the application of both techniques in sports recovery, while highlighting the need for further research in professional athletes and diverse exercise settings to optimize regeneration strategies and reduce injury risk. Full article
(This article belongs to the Special Issue Clinical Aspects of Return to Sport After Injuries)
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20 pages, 5120 KB  
Article
Fast Fourier Transform-Based Activation and Monitoring of Micro-Supercapacitors: Enabling Energy-Autonomous Actuators
by Negar Heidari, Parviz Norouzi, Alireza Badiei and Ebrahim Ghafar-Zadeh
Actuators 2025, 14(9), 453; https://doi.org/10.3390/act14090453 - 16 Sep 2025
Viewed by 422
Abstract
This work provides the first demonstration of FFTCCV as a dual-purpose method, serving both as a real-time diagnostic tool and as a phase- and morphology-engineering strategy. By adjusting the scan rate, FFTCCV directs the crystallographic evolution of Ni (OH)2 on Ni foam—stabilizing [...] Read more.
This work provides the first demonstration of FFTCCV as a dual-purpose method, serving both as a real-time diagnostic tool and as a phase- and morphology-engineering strategy. By adjusting the scan rate, FFTCCV directs the crystallographic evolution of Ni (OH)2 on Ni foam—stabilizing α-nanoflakes at 0.7 V·s−1 and β-platelets at 0.007 V·s−1—while simultaneously enabling electrode-resolved ΔQ tracking and predictive state-of-health (SoH) monitoring. This approach enabled the precise regulation of electrode morphology and phase composition, yielding high areal capacitance (546.5 mF·cm−2 at 5 mA·cm−2) with ~75% retention after 3000 cycles. These improvements advance the development of high-performance micro-supercapacitors, facilitating their integration into wearable and miniaturized devices where compact and durable energy storage is required. Beyond performance enhancement, FFTCCV also enabled continuous monitoring of capacitance during extended operation (up to 40,000 s). By recording both anodic and cathodic responses, the method provided time-resolved insights into device stability and revealed characteristic signatures of electrode degradation, phase transitions, and morphological changes. Such detection allows recognition of early failure pathways that are not accessible through conventional testing. This monitoring capability functions as an embedded health sensor, offering a pathway for predictive diagnosis of supercapacitor failure. Such functionality is particularly important for energy-driven actuators and smart materials, where uninterrupted operation and preventive maintenance are critical. FFTCCV therefore provides a scalable strategy for developing energy-autonomous microsystems with improved performance and real-time state-of-health monitoring. Full article
(This article belongs to the Section Miniaturized and Micro Actuators)
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20 pages, 4448 KB  
Article
AFSS Wide-Frequency Reconfigurable Design and Electromagnetic Characterization Research
by Lei Gong, Xinru Tian, Ge Zhang, Xuan Liu, Shigeng Song, Jian Song, Haoyang Liu, Liguo Wang and Zhiqiang Yang
Electronics 2025, 14(18), 3628; https://doi.org/10.3390/electronics14183628 - 12 Sep 2025
Viewed by 433
Abstract
In order to solve the dynamic adaptation problem of the working frequency band of the FSS in the complex electromagnetic environment and further expand the frequency tuning range, a reconfigurable AFSS unit model based on PIN and varactor diodes are designed, which can [...] Read more.
In order to solve the dynamic adaptation problem of the working frequency band of the FSS in the complex electromagnetic environment and further expand the frequency tuning range, a reconfigurable AFSS unit model based on PIN and varactor diodes are designed, which can achieve the insertion loss below−1 dB in the wide frequency range of 10.2–15.2 GHz, meet the working-band switching, and allow for flexibly adjusting the working frequency point. In order to verify the accuracy of the design method, a square-ring aperture and notched patch-coupling structure that can exhibit broadband transmission response in the X-Ku band is first proposed based on the equivalent circuit model topology. A numerical simulation and a processing test of the structure are carried out. The measured data are in good agreement with the simulation results. After optimizing the unit structure, different capacitance values and resistance values are added to the diodes in the numerical simulation to control the equivalent PIN diode switch and the capacitance change in the varactor diodes. According to the equivalent circuit model and the electric-field intensity distribution, the AFSS regulation mechanism of the loaded diodes is explored. In this paper, through numerical simulation optimizations and experimental verification, the design method and performance optimization strategy of frequency-tunable FSS in the working range of 2–18 GHz are systematically studied, which provides theoretical support for the design of electromagnetic functional devices in the new generation of communication, radar, and electronic warfare systems. Full article
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16 pages, 5357 KB  
Article
Capacitively Coupled CSRR and H-Slot UHF RFID Antenna for Wireless Glucose Concentration Monitoring
by Tauseef Hussain, Jamal Abounasr, Ignacio Gil and Raúl Fernández-García
Sensors 2025, 25(18), 5651; https://doi.org/10.3390/s25185651 - 10 Sep 2025
Viewed by 444
Abstract
This paper presents a fully passive and wireless glucose concentration sensor that integrates a capacitively coupled complementary split-ring resonator (CSRR) with an H-slot UHF RFID antenna. The CSRR serves as the primary sensing element, where changes in glucose concentration alter the effective permittivity [...] Read more.
This paper presents a fully passive and wireless glucose concentration sensor that integrates a capacitively coupled complementary split-ring resonator (CSRR) with an H-slot UHF RFID antenna. The CSRR serves as the primary sensing element, where changes in glucose concentration alter the effective permittivity of the surrounding solution, thereby modifying the resonator capacitance and shifting its resonance behavior. Through near-field capacitive coupling, these dielectric variations affect the antenna input impedance and backscatter response, enabling wireless sensing by modulating the maximum read range. The proposed sensor operates within the 902–928 MHz UHF RFID band and is interrogated using commercial RFID readers, eliminating the need for specialized laboratory equipment such as vector network analyzers. Full-wave electromagnetic simulations and experimental measurements validate the sensor performance, demonstrating a variation in the read range from 6.23 m to 4.67 m as glucose concentration increases from 50 to 200 mg/dL. Moreover, the sensor exhibits excellent linearity, with a high coefficient of determination (R2=0.986) based on the curve-fitted data. These results underscore the feasibility of the proposed sensor as a low-cost and fully portable platform for concentration monitoring, with potential applications in liquid characterization and chemical sensing. Full article
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14 pages, 2114 KB  
Article
Discharge-Based DC-Bus Voltage Link Capacitor Monitoring with Repetitive Recursive Least Squares Method for Hybrid-Electric Aircraft
by Stanisław Oliszewski, Marcin Pawlak and Mateusz Dybkowski
Energies 2025, 18(17), 4743; https://doi.org/10.3390/en18174743 - 5 Sep 2025
Viewed by 791
Abstract
Hybrid-electric aircraft require a reliable power distribution architecture. The electrical drive system is connected to the power source via a DC-link composed mostly of capacitors—one of the faultiest power electronic components. In order to ensure the safe operation of the aircraft, DC-link capacitor [...] Read more.
Hybrid-electric aircraft require a reliable power distribution architecture. The electrical drive system is connected to the power source via a DC-link composed mostly of capacitors—one of the faultiest power electronic components. In order to ensure the safe operation of the aircraft, DC-link capacitor condition monitoring is needed. The main requirements for such an algorithm are low data consumption and the possibility to use it in generator- or battery-powered systems. The proposed discharge-based repetitive recursive least squares (RRLS) method provides satisfactory estimates utilizing small data packages. Its execution during capacitor discharge makes it independent from the power source type. Based on the capacitor’s physical parameters, the computational complexity of the estimation process is reduced. Simulation validation and experimental tests were conducted. An analysis was carried out in a capacitance range between 705 μF and 1175 μF. The effective range of the algorithm is 881 μF–1044 μF, with an estimation error of less than 5%. Additionally, a range of changes in the time constant of the multiplier of 0.1–10 was tested in the simulation study. Full article
(This article belongs to the Special Issue Electric Machinery and Transformers III)
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21 pages, 4327 KB  
Article
Event-Triggered Control of Grid-Connected Inverters Based on LPV Model Approach
by Wensheng Luo, Zhiwei Zhang, Zejian Shu, Haibin Li and Jianwen Zhang
Energies 2025, 18(17), 4739; https://doi.org/10.3390/en18174739 - 5 Sep 2025
Viewed by 814
Abstract
This study aims to develop an event-triggered control strategy of grid-connected inverters, based on the linear parameter-varying (LPV) modeling approach. Regarding the changes in grid voltage, filter capacitance and inductance, and random electromagnetic interference, a stochastic LPV model for three-phase two-level inverters is [...] Read more.
This study aims to develop an event-triggered control strategy of grid-connected inverters, based on the linear parameter-varying (LPV) modeling approach. Regarding the changes in grid voltage, filter capacitance and inductance, and random electromagnetic interference, a stochastic LPV model for three-phase two-level inverters is established. To reduce computation burden, an event trigger with a continuous-time form is adopted to derive the state feedback controller for the LPV plant. Unlike the existing common approach to dealing with event-triggered mechanisms, a predesignated event-triggering threshold is used to determine the triggering instant of the event condition. Using parameter-dependent Lyapunov functions, sufficient conditions reliant on parameters are introduced. Based on the derived conditions, the corresponding event-triggered controllers are engineered to ensure uniform ultimate bounded stability for the resulting event-triggered LPV inverter system subject to exogenous disturbance. The simulation results are presented to confirm the efficacy of the proposed methods. Full article
(This article belongs to the Special Issue Control and Optimization of Power Converters)
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28 pages, 5893 KB  
Article
A Study of the In-Vial Crystallization of Ice in Sucrose–Salt Solutions—An Application for Through-Vial Impedance Spectroscopy (TVIS)
by Geoff Smith and Yowwares Jeeraruangrattana
Appl. Sci. 2025, 15(17), 9728; https://doi.org/10.3390/app15179728 - 4 Sep 2025
Viewed by 626
Abstract
Ice nucleation temperatures and associated ice growth rates are critical parameters in defining the initial ice morphology template, which governs dry layer resistance during sublimation and therefore impacts primary drying kinetics and overall process time. In this study, we developed a through-vial impedance [...] Read more.
Ice nucleation temperatures and associated ice growth rates are critical parameters in defining the initial ice morphology template, which governs dry layer resistance during sublimation and therefore impacts primary drying kinetics and overall process time. In this study, we developed a through-vial impedance spectroscopy (TVIS) method to determine both ice nucleation temperature and average ice growth rate, from which future estimation of average ice crystal size may be possible. Whereas previous TVIS applications were limited to solutions containing simple, uncharged solutes such as sugars, our adapted approach enables the analysis of conductive solutions (5% sucrose with 0%, 0.26%, and 0.55% NaCl), covering osmolarities below and above isotonicity. We established that the real part capacitance at low and high frequencies—either side of the dielectric relaxation of ice—provides the following: (i) a temperature-sensitive parameter for detecting the onset of ice formation, and (ii) a temperature-insensitive parameter for determining the end of the ice growth phase (unaffected by temperature changes in the frozen solution). This expanded capability demonstrates the potential of TVIS as a process analytical technology (PAT) for non-invasive, in situ monitoring of freezing dynamics in pharmaceutical freeze-drying. Full article
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13 pages, 2327 KB  
Communication
Quantitative IC50 Analysis of Puromycin-Induced Cytotoxicity in NIH/3T3 Cells Using a Multi-Well Array Impedance Biosensor
by Seok-kyu Kim, SuGwon Nam and Moongyu Jang
Biosensors 2025, 15(9), 572; https://doi.org/10.3390/bios15090572 - 1 Sep 2025
Viewed by 942
Abstract
ECIS-based impedance biosensors have been extensively studied in various fields including cancer research, microbiology, and immunology. However, most studies have primarily focused on monitoring cellular behavior through impedance changes, with relatively less emphasis on interpreting the biological significance of impedance signals. In this [...] Read more.
ECIS-based impedance biosensors have been extensively studied in various fields including cancer research, microbiology, and immunology. However, most studies have primarily focused on monitoring cellular behavior through impedance changes, with relatively less emphasis on interpreting the biological significance of impedance signals. In this study, we employed a multi-well array impedance biosensor to conduct IC50 (half-maximal inhibitory concentration) analysis, a widely used metric for evaluating drug efficacy and toxicity in biological and pharmacological research. Specifically, we assessed the IC50 values of puromycin, an aminonucleoside antibiotic known to inhibit protein synthesis. NIH/3T3 fibroblasts were exposed to various concentrations of puromycin, and real-time impedance monitoring was performed. Cell viability was assessed, and the IC50 value of puromycin for NIH/3T3 cells was determined to be 3.96 µM using capacitance-based impedance analysis. Our findings demonstrate that the multi-well array impedance biosensor provides a rapid and quantitative method for drug toxicity evaluation, offering a valuable platform for drug screening and biocompatibility assessment. Full article
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20 pages, 3983 KB  
Article
Novel Tunable Pseudoresistor-Based Chopper-Stabilized Capacitively Coupled Amplifier and Its Machine Learning-Based Application
by Mohammad Aleem Farshori, M. Nizamuddin, Renuka Chowdary Bheemana, Krishna Prakash, Shonak Bansal, Mohammad Zulqarnain, Vipin Sharma, S. Sudhakar Babu and Kanwarpreet Kaur
Micromachines 2025, 16(9), 1000; https://doi.org/10.3390/mi16091000 - 29 Aug 2025
Viewed by 677
Abstract
This work presents a high-common-mode-rejection-ratio (CMRR) and high-gain FinFET-based bio-potential amplifier with a novel CMRR reduction technique. In this paper, a feedback buffer is used alongside a capacitively coupled chopper-stabilized circuit to reduce the common-mode signal gain, thus boosting the overall CMRR of [...] Read more.
This work presents a high-common-mode-rejection-ratio (CMRR) and high-gain FinFET-based bio-potential amplifier with a novel CMRR reduction technique. In this paper, a feedback buffer is used alongside a capacitively coupled chopper-stabilized circuit to reduce the common-mode signal gain, thus boosting the overall CMRR of the circuit. The conventional pseudoresistor in the feedback circuit is replaced with a tunable parallel-cell configuration of pseudoresistors to achieve high linearity. A chopper spike filter is used to mitigate spikes generated by switching activity. The mid-band gain of the chopper-stabilized amplifier is 42.6 dB, with a bandwidth in the range of 6.96 Hz to 621 Hz. The noise efficiency factor (NEF) of the chopper-stabilized amplifier is 6.1, and its power dissipation is 0.92 µW. The linearity of the parallel pseudoresistor cell is tested for different tuning voltages (Vtune) and various numbers of parallel pseudoresistor cells. The simulation results also demonstrate the pseudoresistor cell performance for different process corners and temperature changes. The low cut-off frequency is adjusted by varying the parameters of the parallel pseudoresistor cell. The CMRR of the chopper-stabilized amplifier, with and without the feedback buffer, is 106.9 dB and 100.3 dB, respectively. The feedback buffer also reduces the low cut-off frequency, demonstrating its multi-utility. The proposed circuit is compatible with bio-signal acquisition and processing. Additionally, a machine learning-based arrhythmia diagnosis model is presented using a convolutional neural network (CNN) + Long Short-Term Memory (LSTM) algorithm. For arrhythmia diagnosis using the CNN+LSTM algorithm, an accuracy of 99.12% and a mean square error (MSE) of 0.0273 were achieved. Full article
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21 pages, 1655 KB  
Article
Capacitive Biosensing of Skin Irritants Using a Lanolin-Based Artificial Stratum Corneum Model
by Chung-Ting Cheng, Yi Kung, Hung-Yu Chen, Kuang-Hua Chang, Richie L. C. Chen and Tzong-Jih Cheng
Biosensors 2025, 15(9), 564; https://doi.org/10.3390/bios15090564 - 28 Aug 2025
Viewed by 758
Abstract
Skin irritation testing is transitioning toward non-animal alternatives that can replicate the functional properties of the human stratum corneum (SC). To address this need, we report a capacitive biosensing platform that integrates a lanolin-based artificial SC (aSC) for rapid, indicator-free detection of chemical [...] Read more.
Skin irritation testing is transitioning toward non-animal alternatives that can replicate the functional properties of the human stratum corneum (SC). To address this need, we report a capacitive biosensing platform that integrates a lanolin-based artificial SC (aSC) for rapid, indicator-free detection of chemical irritants. The approach leverages a membrane-bound lipid matrix to detect changes in interfacial capacitance caused by chemical exposure. Among candidate materials, lanolin emerged as the most effective SC mimic, showing reproducible baseline stability and responsive dielectric shifts. The system quantifies barrier integrity through the capacitance change rate (ΔC/Δt), which serves as a real-time indicator of irritation potential. By positioning the biosensor as an analog of the SC and monitoring the dielectric environment during short exposures (7.5 min), we shift the paradigm from endpoint-based biochemical assays to rapid, physicochemical screening. This concept supports the advancement of ethical, scalable testing platforms that reduce reliance on animal or cellular models while maintaining sensitivity to barrier-compromising agents. Full article
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26 pages, 10383 KB  
Review
Flexible and Wearable Tactile Sensors for Intelligent Interfaces
by Xu Cui, Wei Zhang, Menghui Lv, Tianci Huang, Jianguo Xi and Zuqing Yuan
Materials 2025, 18(17), 4010; https://doi.org/10.3390/ma18174010 - 27 Aug 2025
Viewed by 1539
Abstract
Rapid developments in intelligent interfaces across service, healthcare, and industry have led to unprecedented demands for advanced tactile perception systems. Traditional tactile sensors often struggle with adaptability on curved surfaces and lack sufficient feedback for delicate interactions. Flexible and wearable tactile sensors are [...] Read more.
Rapid developments in intelligent interfaces across service, healthcare, and industry have led to unprecedented demands for advanced tactile perception systems. Traditional tactile sensors often struggle with adaptability on curved surfaces and lack sufficient feedback for delicate interactions. Flexible and wearable tactile sensors are emerging as a revolutionary solution, driven by innovations in flexible electronics and micro-engineered materials. This paper reviews recent advancements in flexible tactile sensors, focusing on their mechanisms, multifunctional performance and applications in health monitoring, human–machine interactions, and robotics. The first section outlines the primary transduction mechanisms of piezoresistive (resistance changes), capacitive (capacitance changes), piezoelectric (piezoelectric effect), and triboelectric (contact electrification) sensors while examining material selection strategies for performance optimization. Next, we explore the structural design of multifunctional flexible tactile sensors and highlight potential applications in motion detection and wearable systems. Finally, a detailed discussion covers specific applications of these sensors in health monitoring, human–machine interactions, and robotics. This review examines their promising prospects across various fields, including medical care, virtual reality, precision agriculture, and ocean monitoring. Full article
(This article belongs to the Special Issue Advances in Flexible Electronics and Electronic Devices)
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