Search Results (18)

Primary teeth play a crucial role in a child’s development, particularly in maintaining space for permanent teeth. The premature loss of a primary tooth can lead to orthodontic issues, making the use of space maintainers essential to ensure proper growth and development of permanent teeth. To preserve space, the fabrication of a space maintainer is necessary. Since conventional space maintainers do not restore masticatory function, this study presents an innovative solution for space preservation following the extraction of the first primary molar through the design of the functional space maintainer KOS&MET (Key Orthodontic System and Materials Enhanced Therapy). The space maintainer was designed using the 3Shape Dental Designer 2023 version software tool and manufactured via additive 3D printing, utilizing a metal alloy with high resistance to masticatory forces. The crown is supported by the primary canine, while an intraoral window is created to monitor the eruption of the successor tooth. This design does not interfere with occlusion and enables bilateral chewing. Masticatory performance was assessed using two-color chewing gum, and the results showed improvement after cementing the space maintainer. This innovative approach not only preserves space for permanent teeth but also enhances masticatory function, contributing to the proper growth and development of the jaws and teeth. Full article

When a CMOS (Complementary Metal–Oxide–Semiconductor) imaging system operates at a high frame rate or a high line rate, the exposure time of the imaging system is limited, and the acquired image data will be dark, with a low signal-to-noise ratio and unsatisfactory sharpness. Therefore, in order to improve the visibility and signal-to-noise ratio of remote sensing images based on CMOS imaging systems, this paper proposes a low-light remote sensing image enhancement method and a corresponding ZYNQ (Zynq-7000 All Programmable SoC) design scheme called the BGIR (Bilateral-Guided Image Restoration) algorithm, which uses an improved multi-scale Retinex algorithm in the HSV (hue–saturation–value) color space. First, the RGB image is used to separate the original image’s H, S, and V components. Then, the V component is processed using the improved algorithm based on bilateral filtering. The image is then adjusted using the gamma correction algorithm to make preliminary adjustments to the brightness and contrast of the whole image, and the S component is processed using segmented linear enhancement to obtain the base layer. The algorithm is also deployed to ZYNQ using ARM + FPGA software synergy, reasonably allocating each algorithm module and accelerating the algorithm by using a lookup table and constructing a pipeline. The experimental results show that the proposed method improves processing speed by nearly 30 times while maintaining the recovery effect, which has the advantages of fast processing speed, miniaturization, embeddability, and portability. Following the end-to-end deployment, the processing speeds for resolutions of 640 × 480 and 1280 × 720 are shown to reach 80 fps and 30 fps, respectively, thereby satisfying the performance requirements of the imaging system. Full article

Parks play a crucial role in mitigating urban heat island effects, a key challenge for urban sustainability. Park cooling intensity (PCI) mechanisms across varying canopy-layer urban heat island (CUHI) gradients remain underexplored, particularly regarding interactions with meteorological, topographical, and socio-economic factors. According to the urban-suburban air temperature difference, this study classified the city into non-, weak, and strong CUHI regions. We integrated causal inference, machine learning and a geographical detector (Geodetector) to model and interpret PCI dynamics across CUHI gradients. The results reveal that surrounding impervious surface coverage is a universal driver of PCI by enhancing thermal contrast at park boundaries. However, the dominant drivers of PCI varied significantly across CUHI gradients. In non-CUHI regions, surrounding imperviousness dominated PCI and exhibited bilaterally enhanced interaction with intra-park patch density. Weak CUHI regions relied on intra-park green coverage with nonlinear synergies between water body proportion and park area. Strong CUHI regions involved systemic urban fabric influences mediated by surrounding imperviousness, evidenced by a validated causal network. Crucially, causal inference reduces model complexity by decreasing predictor counts by 79%, 25% and 71% in non-, weak and strong CUHI regions, respectively, while maintaining comparable accuracy to full-factor models. This outcome demonstrates the efficacy of causal inference in eliminating collinear metrics and spurious correlations from traditional feature selection, ensuring retained predictors reside within causal pathways and support process-based interpretability. Our study highlights the need for context-adaptive cooling strategies and underscores the value of integrating causal–statistical approaches. This framework provides actionable insights for designing climate-resilient blue–green spaces, advancing urban sustainability goals. Future research should prioritize translating causal diagnostics into scalable strategies for sustainable urban planning. Full article

Background: Evaluating the effectiveness and survival rates of space maintainers is crucial for optimal pediatric dental care. The present study’s goal is to evaluate the survival rate of different types of space maintainers—removable, fixed with a metal base, or fixed with a resin base—indicated for children as a consequence of premature loss of primary teeth. Methods: A systematic review was conducted in accordance with PRISMA recommendations and was previously registered in PROSPERO under registration number: CRD42024534183. The search was performed in five different databases PubMed, EMBASE, Scopus, Cochrane, and Web of Science. This was supplemented by a manual database search. From the initial electronic search of the five databases, 72 articles were identified after removing duplicates. After reading the titles and abstracts, 46 articles were excluded, leaving a total of 26 studies. Upon reading the full texts, 15 were excluded for not meeting the inclusion criteria, resulting in a total of 11 articles included in the systematic review. Results: The total number of patients treated in the studies was 479, with four observational studies and seven randomized clinical trials. Fixed space maintainers, such as band and loop (BL) or lingual arch (LA), are preferred due to their long-term stability and lower risk of loss. In contrast, removable maintainers, such as Hawley plates, are suitable temporarily but require more patient cooperation and may be less tolerated. Conclusions: Space maintainers help prevent the migration of adjacent teeth and the need for more invasive orthodontic treatments in the future. Additionally, they contribute to adequate masticatory function and speech development. Full article

Aims: It was the scope of this study to explore the biomechanical implications of retraction force application point modifications in lingual orthodontics, aiming to mitigate the bowing effect and enhance anchorage stability in the anterior teeth. Methods: Using the FE method on an idealized maxillary model, en masse retraction was simulated using a modified lingual fixed appliance including edgewise lingual brackets, a 0.017″ × 0.025″ mushroom-shaped archwire, and power arms between lateral incisors and canines, with a transpalatal arch (TPA) connecting the first molars. Applying bilateral retraction forces of 1.5 N at twelve positions, initial tooth displacements during space closure were evaluated. Results: Shifting power arms gingivally did not effectively counteract palatal tipping of incisors but reduced posterior and palatal tipping of canines with a power arm length of 11.3 mm preventing posterior tipping. Apically displacing the TPA retraction force increased mesiobuccal rotation while preventing mesial molar tipping for retraction forces applied 12.6 mm from the archwire. Conclusions: Apically shifting retraction forces can mitigate vertical bowing effects in lingual orthodontics, yet it also highlights the challenges in maintaining torque in the anterior teeth. Further research and clinical validation are essential in order to confirm these results, emphasizing the complexity and need for advanced biomechanical strategies in personalized lingual orthodontic treatments. Full article

This case report presents a virtual treatment simulation of the orthodontic treatment and surgery-first orthognathic surgery employed to treat a patient with a repaired unilateral cleft lip and alveolus with Class III malocclusion and lower third facial asymmetry. The patient exhibited a negative overjet of 9 mm, a missing lower right second premolar, and a 5 mm gap between the upper right central and lateral incisors with midline discrepancy. The three-dimensional virtual planning began with virtual pre-surgical orthodontics, followed by the positioning of the facial bones and teeth in their ideal aesthetic and functional positions. The sequence of steps needed to achieve this outcome was then reverse-engineered and recorded using multiplatform Nemostudio software (Nemotec, Madrid, Spain), which facilitated both surgical and orthodontic planning. The treatment included a two-piece segmental maxillary osteotomy for dental space closure, a LeFort I maxillary advancement, and a mandibular setback with bilateral sagittal split osteotomy to correct the skeletal underbite and asymmetry. A novel approach was employed by pre-treating the patient for orthognathic surgeries at age 11, seven years prior to the surgery. This early phase of orthodontic treatment aligned the patient’s teeth and established the dental arch form. The positions of the teeth were maintained with retainers, eliminating the need for pre-surgical orthodontics later. This early phase of treatment significantly reduced the treatment time. The use of software to predict all the necessary steps for surgery and post-surgical orthodontic tooth movements made this approach possible. Multi-step virtual planning can be a powerful tool for analyzing complex craniofacial problems that require multidisciplinary care, such as cleft lip and/or palate. Full article

Background/Objectives: Perineal reconstruction after abdominoperineal excision often requires complex closures and is fraught with wound healing complications. Flap-based approaches introduce non-irradiated vascularized tissue to the area of resection to fill a large soft-tissue defect and dead space, reduce the risk of infection, and facilitate wound healing. Employing perforator flaps with their beneficial donor site properties, the authors have developed a concept of bilateral superior gluteal artery perforator (SGAP) flaps to restore extensive perineal defects. Methods: This retrospective case series was conducted between September 2015 and December 2019. We included three patients who received bilateral SGAP flap reconstruction after oncological resection. One deepithelialized SGAP flap was used for obliteration of dead space, combined with the contralateral SGAP flap for superficial defect reconstruction and wound closure. Results: Within this patient population, two male and one female patient, with a median age of 62 years (range, 52–76 years), were included. Six pedicled SGAP flaps were performed with average flap dimensions of 9 × 20 cm (range 7–9 × 19 × 21). No flap loss or no local recurrence were documented. In one case, partial tip necrosis with prolonged serous drainage was observed, which was managed by surgical debridement. No further complications were detected. Conclusions: The combination of two SGAP flaps provides maximal soft tissue for defect reconstruction and obliteration of dead space, while maintaining a very inconspicuous donor site, even with bilateral harvesting. Given these advantages, the authors recommend this promising approach for successful reconstruction of perineal defects. Full article

The 2023 SDGs report underscores the prolonged disruption of COVID-19 on community living spaces, infrastructure, education, and income equality, exacerbating social and spatial inequality. Against the backdrop of the dual impact of significant events and the emergence of digital technologies, a coherent research trajectory is essential for characterizing social–spatial equity and understanding its influential factors within the urban planning discipline. While prior research emphasized spatial dimensions and mitigated spatial differentiation to ensure urban equity, the complexity of these interconnections necessitates a more comprehensive approach. This study adopts a holistic perspective, focusing on the “social–spatial” dynamics, utilizing social perception (sentiment maps) and spatial differentiation (housing prices index) pre- and post-pandemic to elucidate the interconnected and interactive nature of uneven development at the urban scale. It employs a multi-dimensional methodological framework integrating morphology analysis of housing conditions, GIS analysis of urban amenities, sentiment semantic analysis of public opinion, and multiscale geographically weighted regression (MGWR) analysis of correlation influential factors. Using Suzhou, China, as a pilot study, this research demonstrates how these integrated methods complement each other, exploring how community conditions and resource distribution collectively bolster resilience, thereby maintaining social–spatial equity amidst pandemic disruptions. The findings reveal that uneven resource distribution exacerbates post-pandemic social stratification and spatial differentiation. The proximity of well-maintained ecological environments, such as parks or scenic landmarks, generally exhibits consistency and positive effects on “social–spatial” measurement. Simultaneously, various spatial elements influencing housing prices and social perception show geographic heterogeneity, particularly in areas farther from the central regions of Xiangcheng and Wujiang districts. This study uncovers a bilateral mechanism between social perception and spatial differentiation, aiming to delve into the interdependent relationship between social–spatial equity and built environmental factors. Furthermore, it aspires to provide meaningful references and recommendations for urban planning and regeneration policy formulation in the digital era to sustain social–spatial equity. Full article

Quantitative assessment and visual analysis of the multidimensional features of international bilateral product trade are crucial for global trade research. However, current methods face poor salience and expression issues when analysing the characteristics of China—Australia bilateral trade from 1998 to 2019. To address this, we propose a new perspective that involves period division, feature extraction, construction of product space, and spatiotemporal analysis by selecting the display competitive advantage index using the digital trade feature map (DTFM) method. Our results reveal that the distribution of product importance in China—Australia bilateral trade is heavy-tailed, and that the number of essential products has decreased by 68% over time. The proportion of products in which China dominates increased from 71% to 77%. Furthermore, Australia consistently maintains dominance in the most crucial development in trade, and the supremacy of the head product is becoming stronger. Based on these findings, the stability of bilateral trade between Australia and China is declining, and the pattern of polarisation in the importance of traded products is worsening. This paper proposes a novel method for studying Sino—Australian trade support. The analytical approach presented can be extended to analyse the features of bilateral trade between other countries. Full article

Background: Postural control is a complex ability, also controlled by the somatosensory connection of the neck muscles with the vestibular nuclei. This circuit seems to be interested in maintaining head stabilization during movements. The sternocleidomastoid (SCM) muscle is the dominant source of the vestibular afferents as confirmed by neurophysiological acquisition. The aim of this study is to evaluate whether the application of kinesio-tape on the SCM muscle can induce a perturbation of the standing postural control by altering the somatosensory system of the neck muscles. Methods: Thirteen healthy participants (age: 24.46 ± 3.04 yrs; 9 female) were enrolled, and the four kinesio-tape (KT) conditions were performed in a random order: without KT application (Ctrl); right KT application (R-SCM); left KT application (L-SCM); and bilateral KT application (B-SCM). All conditions were performed three times with open eyes and closed eyes. Results: There was a significant increase in the length of the centre of pressure (CoP), in the maximal oscillation, and in the anteroposterior root mean square between the three tape application conditions with respect to the Ctrl condition with open eyes. The same parameters were statistically different when the participants were blindfolded in the B-SCM condition with respect to the Ctrl condition. A statistical decrease in the difference in weight distribution between the two feet was observed in the B-SCM group with respect to the Ctrl group in both open and closed eyes conditions. Conclusions: Our results suggest that KT on the SCM muscles may involve some space-time parameters of postural control. Bilateral KT improved the weight distribution between the feet but showed a parallel increase in anteroposterior oscillations and in the length of the CoP with respect to the Ctrl condition. The perturbation seems to be greater in the somatosensory system when it is working coupled with visual afferences during an upright position. Full article

Background and Objectives: The foot comprises of active contractile and passive connective tissue components, which help maintain stability and facilitate movement during gait. The role of age- or pathology-related degeneration and the presence of fat within muscles in foot function and pain remains unclear. The existence of fat has to date not been quantified or compared between individuals according to age, sex, side or subregion. Materials and Methods: 18 cadaveric feet (mean age 79 years) were sectioned sagittally and photographed bilaterally. Fat in the plantar muscular space of the foot (PMSF) was quantified through the previously validated manual fat quantification method, which involved observing photographs of each section and identifying regions using OsiriX. Fat volume and percentage was calculated using a modified Cavalieri’s method. Results: All feet had fat located within the PMSF, averaging 25.8% (range, 16.5–39.4%) of the total PMSF volume. The presence of fat was further confirmed with plastination and confocal microscopy. Conclusions: These findings suggest that fat within the PMSF is a consistent but highly variable finding in elderly cohorts. Fat within the foot muscles may need to be considered a norm when comparing healthy and non-healthy subjects, and for therapeutic interventions to the foot. Further work is required to understand in detail the morphological and mechanical presence of fat in the foot, and compare these findings with pathological cohorts, such as sarcopenia. Additionally, future work should investigate if fat may compensate for the degeneration of the intrinsic muscles of the foot, with implications for both the use of orthotics and pain management. Full article

Various biomaterial combinations have been studied focusing on their ability to stabilize blood clots and maintain space under soft tissue to support new bone formation. A popular combination is Deproteinized Bovine Bone Mineral (DBBM) placed with a native collagen membrane (NCM) tacked to native bone. In this study, we compared the outcome of this treatment option to those achieved with three different graft/membrane combinations with respect to total newly occupied area and the mineralized compound inside. After bi-lateral extraction of two mandibular premolars in five adult beagles L-shaped alveolar defects were created. A total of 20 defects healed for 6 weeks resulting in chronic type bone defects. At baseline, four options were randomly allocated to five defects each: a. DBBM + NCM with a four-pin fixation across the ridge; b. DBBM + RCLC (ribose cross-linked collagen membrane); c. DBBM + NPPM (native porcine pericardium membrane); and d. Ca-sulfate (CS) + RCLC membrane. Membranes in b/c/d were not fixed; complete tensionless wound closure was achieved by CAF. Termination after 3 months and sampling followed, and non-decalcified processing and toluidine blue staining were applied. Microscopic images obtained at standardized magnification were histomorphometrically assessed by ImageJ software (NIH). An ANOVA post hoc test was applied; histomorphometric data are presented in this paper as medians and interquartile ranges (IRs). All sites healed uneventfully, all sites were sampled and block separation followed before Technovit embedding. Two central sections per block for each group were included. Two of five specimen were lost due to processing error and were excluded from group b. New bone area was significantly greater for option b. compared to a. (p = 0.001), c. (p = 0.002), and d. (p = 0.046). Residual non-bone graft area was significantly less for option d. compared to a. (p = 0.026) or c. (p = 0.021). We conclude that collagen membranes with a prolonged resorption/barrier profile combined with bone substitutes featuring different degradation profiles sufficiently support new bone formation. Tacking strategy/membrane fixation appears redundant when using these biomaterials. Full article

The purpose of this study was to determine the analgesic efficacy and safety of epidural lidocaine-xylazine administration in standing mules undergoing elective bilateral laparoscopic ovariectomy in order to suppress unwanted behaviour. Eight mule mares were sedated with intramuscular 0.05 mg/kg acepromazine followed by 1.3 mg/kg of xylazine and 0.02 mg/kg of butorphanol intravenously. Sedation was maintained by a constant rate infusion of 0.6 mg/kg/h of xylazine. The paralumbar fossae were infiltrated with 30 mL of 2% lidocaine. Epidural anaesthesia was performed at the first intercoccygeal space with 0.2 mg/kg of lidocaine and 0.17 mg/kg of xylazine. After 15 min, bilateral laparoscopic ovariectomy was performed. Heart rate, respiratory rate, rectal temperature, invasive arterial blood pressure, degree of analgesia, sedation and ataxia were evaluated during surgery. The laparoscopic ovariectomy was successfully completed in all animals. Sedation and analgesia were considered satisfactory in six out of the eight mules. In conclusion, caudal epidural block allowed surgery to be easily completed in six out of eight. The animals did not show any signs of discomfort associated with nociception and were mostly calm during the procedures, however additional studies are needed to establish epidural doses of xylazine and lidocaine that result in reliable abdominal pain control in mules for standing ovariectomy. Full article

Human postural control is regulated by the vestibular, somatosensory, and visual systems. These types of sensory information are integrated in the central nervous system to ascertain the body’s position in space. Proper functioning of the vestibular, somatosensory, and visual senses is necessary for the body to maintain equilibrium. Bilateral vestibulopathy (BVP) is a condition in which bilateral peripheral vestibular function is reduced. Its treatment includes vestibular rehabilitation (VeR), balance training, counseling, treating the underlying cause, and avoiding further damage to the vestibular system. As VeR is often tedious for patients, patient motivation is required or patients may drop out of the program. To solve this problem, in recent years, there have been increasing reports of VeR using virtual reality, which increases vestibulo-ocular reflex gain and decreased dizziness by inducing adaptation. In this review, we discuss VeR, particularly for BVP, and VeR using virtual reality. Full article

Background: Among tooth anomalies, missing teeth is one of the most frequent, and it can be related to different therapeutical sets of problems. Often, an integrated approach that interests both orthodontists and prosthodontists is necessary, and in some cases also the periodontists. Methods: In this paper the authors report a clinical case of a 14-year-old patient, affected by maxillary bilateral incisors agenesis, molar bilateral II class and deep bite, treated in the Department of Orthodontics and Pedodontics of the University of Messina. The orthodontic treatment target was the distal movement of the maxillary molar, and the recovery of the space necessary for the prosthetic restoration of the missing lateral incisor. Maxillary molars distal movement was performed with a Distal Jet apparatus, skeletally supported by two miniscrews (Distal-Screw, American Orthodontics, Sheboygan, WI, USA). After molar relationship correction, a multi-bracket bimaxillary orthodontic appliance was bonded using Empower Brackets (American Orthodontics, Sheboygan, WI, USA). At the end of orthodontic treatment a Maryland bridge, bonded on the central incisors and cuspids, was used in order to maintain the space necessary for the insertion of dental implants in the region of 1.2 and 2.2. Results: A class II molar relationship was corrected, with an improvement of the deep bite, and the space necessary for implant insertion was recovered Conclusion: A skeletally supported Distal Jet was efficient for molar distalization, with the advantage of not having any loss of anchorage in the anterior part of the dental arch. This apparatus does not need patient compliance, have favorable aesthetics and also give the possibility to perform asymmetric activations. Full article