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  • Article
  • Open Access
13 Citations
3,266 Views
12 Pages

Nitric Oxide Does Not Inhibit but Is Metabolized by the Cytochrome bcc-aa3 Supercomplex

  • Elena Forte,
  • Alessandro Giuffrè,
  • Li-shar Huang,
  • Edward A. Berry and
  • Vitaliy B. Borisov

12 November 2020

Nitric oxide (NO) is a well-known active site ligand and inhibitor of respiratory terminal oxidases. Here, we investigated the interaction of NO with a purified chimeric bcc-aa3 supercomplex composed of Mycobacterium tuberculosis cytochrome bcc and M...

  • Review
  • Open Access
17 Citations
3,481 Views
22 Pages

The production of reactive nitrogen species (RNS) by the innate immune system is part of the host’s defense against invading pathogenic bacteria. In this review, we summarize recent studies on the molecular basis of the effects of nitric oxide...