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30 pages, 20041 KB  
Article
A Design Methodology for RF/mmWave LNAs in 22 nm FD-SOI with Cross-Coupling-Aware Nested Inductors and On-Chip Baluns
by Stavros Drakakis, Anastasios Michailidis, Dimitrios Tzagkas, Vasilis F. Pavlidis and Thomas Noulis
Electronics 2026, 15(1), 25; https://doi.org/10.3390/electronics15010025 - 21 Dec 2025
Viewed by 882
Abstract
In this work, a layout-level design methodology is presented for Low-Noise Amplifiers (LNAs), targeting a wide frequency spectrum from RF to millimeter-wave (mmWave) bands, and implemented using a 22 nmFDSOI CMOS process. A nested inductor structure is introduced at RF frequencies to reduce [...] Read more.
In this work, a layout-level design methodology is presented for Low-Noise Amplifiers (LNAs), targeting a wide frequency spectrum from RF to millimeter-wave (mmWave) bands, and implemented using a 22 nmFDSOI CMOS process. A nested inductor structure is introduced at RF frequencies to reduce silicon footprint, with magnetic crosstalk effects characterized through electromagnetic (EM) simulations using Ansys® RaptorX, Release 2024 R2, ANSYS, Inc. and integrated into the design process. Single-ended LNA architectures are employed for RF bands, while at mmWave frequencies, a differential topology is adopted to enhance linearity and enable simultaneous input and output impedance matching. An EM-based verification flow is applied across all designs to ensure RF/mmWave design flow compatibility, simulation accuracy, and enhanced performance. The proposed designs are evaluated using key metrics including input/output matching, reverse isolation, forward gain, noise figure, linearity (IP1,IP3), stability factor, power consumption, and total chip area to quantify the efficiency of the proposed methodology. The simulation results demonstrate that nested inductors are highly effective for area reduction in RF LNAs, while differential topologies are more suitable for mmWave designs, providing a unified framework for area-efficient and high performance LNA implementation. Full article
(This article belongs to the Special Issue CMOS Integrated Circuits Design)
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11 pages, 3720 KB  
Communication
The Design of a 140 GHz 28 nm CMOS Vector-Sum Phase Shifter Based on Gilbert Cell and Current-Steering Amplifiers
by Junyung Cho, Jung-Hyun Lee and M. Kim
Chips 2025, 4(4), 50; https://doi.org/10.3390/chips4040050 - 13 Nov 2025
Viewed by 1289
Abstract
This paper presents the design of a 140 GHz vector-sum phase shifter in a 28 nm CMOS process. Two variable-gain amplifiers—Gilbert cell and current-steering amplifiers—are investigated and compared. The Gilbert cell-based phase shifter controls the tail current source in a common-source amplifier. However, [...] Read more.
This paper presents the design of a 140 GHz vector-sum phase shifter in a 28 nm CMOS process. Two variable-gain amplifiers—Gilbert cell and current-steering amplifiers—are investigated and compared. The Gilbert cell-based phase shifter controls the tail current source in a common-source amplifier. However, this configuration exhibits insufficient gain at D-band frequencies. To address this issue, we designed a current-steering variable-gain amplifier in cascode form to improve the gain performance. I/Q signals are generated by Marchand baluns and Lange couplers, and a 13-bit digital-to-analog converter enables fine bias control. Simulation results show that the current-steering phase shifter achieves up to a 4.4 dB higher gain than the Gilbert cell-based phase shifter, with an RMS gain error below 1.3 dB and an RMS phase error below 4.8° across 129–144 GHz. Full article
(This article belongs to the Special Issue IC Design Techniques for Power/Energy-Constrained Applications)
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14 pages, 2087 KB  
Article
A 28-nm CMOS Low-Power/Low-Voltage 60-GHz LNA for High-Speed Communication
by Minoo Eghtesadi, Andrea Ballo, Gianluca Giustolisi, Salvatore Pennisi and Egidio Ragonese
Electronics 2025, 14(14), 2819; https://doi.org/10.3390/electronics14142819 - 13 Jul 2025
Cited by 1 | Viewed by 2172
Abstract
This paper presents a wideband low-power/low-voltage 60-GHz low-noise amplifier (LNA) in a 28-nm bulk CMOS technology. The LNA has been designed for high-speed millimeter-wave (mm-wave) communications. It consists of two pseudo-differential amplifying stages and a buffer stage included for 50-Ohm on-wafer measurements. Two [...] Read more.
This paper presents a wideband low-power/low-voltage 60-GHz low-noise amplifier (LNA) in a 28-nm bulk CMOS technology. The LNA has been designed for high-speed millimeter-wave (mm-wave) communications. It consists of two pseudo-differential amplifying stages and a buffer stage included for 50-Ohm on-wafer measurements. Two integrated input/output baluns guarantee both simultaneous 50-ohm input–noise/output matching at input/output radio frequency (RF) pads. A power-efficient design strategy is adopted to make the LNA suitable for low-power applications, while minimizing the noise figure (NF). Thanks to the adopted design strategy, the post-layout simulation results show an excellent trade-off between power gain and 3-dB bandwidth (BW3dB) with 13.5 dB and 7 GHz centered at 60 GHz, respectively. The proposed LNA consumes only 11.6 mA from a 0.9-V supply voltage with an NF of 8.4 dB at 60 GHz, including the input transformer loss. The input 1 dB compression point (IP1dB) of −15 dBm at 60 GHz confirms the first-rate linearity of the proposed amplifier. Human body model (HBM) electrostatic discharge (ESD) protection is guaranteed up to 2 kV at the RF input/output pads thanks to the input/output integrated transformers. Full article
(This article belongs to the Special Issue 5G Mobile Telecommunication Systems and Recent Advances, 2nd Edition)
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15 pages, 3025 KB  
Article
High-Power-Density Miniaturized VLF Antenna with Nanocrystalline Core for Enhanced Field Strength
by Wencheng Ai, Huaning Wu, Lin Zhao and Hui Xie
Nanomaterials 2025, 15(14), 1062; https://doi.org/10.3390/nano15141062 - 9 Jul 2025
Cited by 1 | Viewed by 1395
Abstract
In order to break through the difficulties with a very-low-frequency (VLF) miniaturized antenna with small power capacity and low radiation efficiency, this paper proposes a high-radiation-field-strength magnetic loop antenna based on a nanocrystalline alloy magnetic core. A high-permeability nanocrystalline toroidal core (μ [...] Read more.
In order to break through the difficulties with a very-low-frequency (VLF) miniaturized antenna with small power capacity and low radiation efficiency, this paper proposes a high-radiation-field-strength magnetic loop antenna based on a nanocrystalline alloy magnetic core. A high-permeability nanocrystalline toroidal core (μr = 50,000, Bs = 1.2 T) is used to optimize the thickness-to-diameter ratio (t = 0.08) and increase the effective permeability to 11,000. The Leeds wires, characterized by their substantial carrying capacity, are manufactured through a toroidal winding process. This method results in a 68% reduction in leakage compared to traditional radial winding techniques and enhances magnetic induction strength by a factor of 1.5. Additionally, this approach effectively minimizes losses, thereby facilitating support for kilowatt-level power inputs. A cascaded LC resonant network (resonant capacitance 2.3 μF) and ferrite balun transformer (power capacity 3.37 kW) realize a 20-times amplification of the input current. A series connection of a high-voltage isolation capacitor blocks DC bias noise, guaranteeing the stable transmission of 1200 W power, which is 6 times higher than the power capacity of traditional ring antenna. At 7.8 kHz frequency, the magnetic field strength at 120 m reaches 47.32 dBμA/m, and, if 0.16 pT is used as the threshold, the communication distance can reach 1446 m, which is significantly better than the traditional solution. This design marks the first instance of achieving kilowatt-class VLF effective radiation in a compact 51 cm-diameter magnetic loop antenna, offering a highly efficient solution for applications such as mine communication and geological exploration. Full article
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18 pages, 3361 KB  
Article
Broadband Low-Cost Normal Magnetic Field Probe for PCB Near-Field Measurement
by Ruichen Luo, Zheng He and Lixiao Wang
Sensors 2025, 25(13), 3874; https://doi.org/10.3390/s25133874 - 21 Jun 2025
Cited by 1 | Viewed by 1685
Abstract
This paper presents a broadband near-field probe designed for measuring the normal magnetic field (Hz) in radio frequency (RF) circuits operating within a frequency range of 2–8 GHz. The proposed probe uses a cost-effective 4-layer printed circuit board (PCB) structure [...] Read more.
This paper presents a broadband near-field probe designed for measuring the normal magnetic field (Hz) in radio frequency (RF) circuits operating within a frequency range of 2–8 GHz. The proposed probe uses a cost-effective 4-layer printed circuit board (PCB) structure made with an FR-4 substrate. The probe primarily consists of an Hz detection unit, a broadband microstrip balun, and a coaxial-like output. The broadband balun facilitates the conversion from differential to single-ended signals, thereby enhancing the probe’s common-mode rejection capability. This design ensures that the probe achieves both cost efficiency and high broadband measurement performance. Additionally, this work investigates the feasibility of employing microstrip lines as calibration standards for the Hz probe. The probe’s structural parameters and magnetic field response were initially determined through simulations, and the calibration factor was subsequently verified by calibration experiments. In practical measurements, the field distributions above a microstrip line and a low-noise amplifier (LNA) were captured. The measured field distribution of the microstrip line was compared with simulation results to verify the probe’s performance. Meanwhile, the measured field distribution of the LNA was utilized to identify the radiating components within the amplifier. Full article
(This article belongs to the Section Electronic Sensors)
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16 pages, 7546 KB  
Article
Differential-Fed Wideband Circularly Polarized SIW Cavity-Backed Slot Antenna Array
by Chao Wang, Xiao-Chun Li and David Keezer
Electronics 2025, 14(12), 2389; https://doi.org/10.3390/electronics14122389 - 11 Jun 2025
Cited by 2 | Viewed by 1157
Abstract
This paper presents a wideband circularly polarized (CP) substrate-integrated waveguide (SIW) cavity-backed slot antenna array arranged in a 2 × 2 configuration with differential feeding structures. The design features arc-shaped microstrips within the SIW cavity to excite the TE011x/ [...] Read more.
This paper presents a wideband circularly polarized (CP) substrate-integrated waveguide (SIW) cavity-backed slot antenna array arranged in a 2 × 2 configuration with differential feeding structures. The design features arc-shaped microstrips within the SIW cavity to excite the TE011x/TE101y and TE211y/TE121x modes. By overlapping the center frequencies of the two modes, wideband CP radiation is achieved. The introduction of four modified ring couplers composes a simple but efficient differential feeding network, eliminating the need for balanced resistors like baluns, making it more suitable for millimeter wave or even higher frequency applications. Experimental results show that the antenna array achieves a −10 dB impedance bandwidth of 32.6% (from 17.28 to 24.00 GHz), a 3 dB axial ratio (AR) bandwidth of 13.8% (from 17.05 to 19.57 GHz), a 3 dB gain bandwidth of 41.8% (from 15.39 to 23.51 GHz) and a peak gain of 10.6 dBi, with results closely matching simulation data. This study enhances the development of differential CP SIW cavity-backed slot antenna arrays, offering a potential solution for creating compact integrated front-end circuits in the millimeter wave or Terahertz frequency range. Full article
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17 pages, 5570 KB  
Article
Analysis and Design of Class-D Outphasing Power Amplifier with Non-Isolating Balun Combiner
by Jiyun Bae, Munsu Jeong, Sangjin Yoo, Ilku Nam and Ockgoo Lee
Electronics 2025, 14(11), 2196; https://doi.org/10.3390/electronics14112196 - 28 May 2025
Cited by 1 | Viewed by 1411
Abstract
This paper presents a class-D outphasing power amplifier (PA) that incorporates a non-isolating balun combiner employing a 180° phase shift. Both isolating and non-isolating outphasing combiners are analyzed for signal restoration and combining efficiency. The proposed non-isolating balun combiner employing the 180° phase [...] Read more.
This paper presents a class-D outphasing power amplifier (PA) that incorporates a non-isolating balun combiner employing a 180° phase shift. Both isolating and non-isolating outphasing combiners are analyzed for signal restoration and combining efficiency. The proposed non-isolating balun combiner employing the 180° phase shift was experimentally evaluated and compared with a commercial isolating Wilkinson combiner. When two constant-envelope signals derived from a 10 MHz long-term evolution (LTE) signal are applied to the inputs of the outphasing combiners, both combiners demonstrate successful signal reconstruction. The measured adjacent channel leakage ratios (ACLRs) are −47 dBc for the Wilkinson combiner and −46 dBc for the proposed balun combiner. At 6 dB power back-off (PBO), the proposed balun combiner achieves a combining efficiency of 85.1%, representing an improvement of nearly 60% over the Wilkinson combiner. With a center frequency of 650 MHz, targeting 5G FR1 applications, a class-D outphasing PA was designed in a 28 nm CMOS process using the measured S-parameter data from both outphasing combiners. Simulation results show that the class-D outphasing PA incorporating the proposed balun combiner achieves a peak drain efficiency (DE) of 82.9% with an output power of 17.7 dBm. At 6 dB PBO, the DE reaches 61%, which is approximately 37% higher than that of the outphasing PA using the Wilkinson combiner. Moreover, the designed outphasing PA supports broadband operation over the 360–860 MHz range. Full article
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14 pages, 9820 KB  
Article
Design and Analysis of an Ultra-Wideband High-Precision Active Phase Shifter in 0.18 μm SiGe BiCMOS Technology
by Hao Jiang, Zenglong Zhao, Nengxu Zhu and Fanyi Meng
J. Low Power Electron. Appl. 2025, 15(2), 30; https://doi.org/10.3390/jlpea15020030 - 7 May 2025
Viewed by 2441
Abstract
This paper presents an active phase shifter for phased array system applications, implemented using 0.18 μm SiGe BiCMOS technology. The phase shifter circuit consists of a wideband quadrature signal generator, a vector modulator, an input balun, and an output balun. To enhance the [...] Read more.
This paper presents an active phase shifter for phased array system applications, implemented using 0.18 μm SiGe BiCMOS technology. The phase shifter circuit consists of a wideband quadrature signal generator, a vector modulator, an input balun, and an output balun. To enhance the bandwidth, a polyphase filter is employed as the quadrature signal generator, and a two-stage RC-CR filter with a highly symmetrical miniaturized layout is cascaded to create multiple resonant points, thus extending the phase shifter’s bandwidth to cover the required range. The gain of the variable-gain amplifier within the vector modulator is adjustable by varying the tail current, thereby enlarging the range of selectable points, improving phase-shifting accuracy, and reducing gain fluctuations. The measurement results show that the proposed active phase shifter achieves an RMS phase error of less than 2° and a gain variation ranging from −1.2 dB to 0.1 dB across a 20 GHz to 30 GHz bandwidth at room temperature. The total chip area is 0.4 mm2, with a core area of 0.165 mm2, and consumes 19.5 mW of power from a 2.5 V supply. Full article
(This article belongs to the Topic Advanced Integrated Circuit Design and Application)
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12 pages, 3152 KB  
Article
Differential Phase Coupler Using Balun-Type Power Divider
by Chatrpol Pakasiri, Chung-Yu Chang and Sen Wang
Micromachines 2025, 16(5), 496; https://doi.org/10.3390/mi16050496 - 24 Apr 2025
Viewed by 1148
Abstract
This paper presents a differential phase coupler design methodology in the IPD process. The coupler consists of a balun and two phase-shifter circuits. The compact balun was designed with lumped components and a common inductor. Each output of the balun circuit was connected [...] Read more.
This paper presents a differential phase coupler design methodology in the IPD process. The coupler consists of a balun and two phase-shifter circuits. The compact balun was designed with lumped components and a common inductor. Each output of the balun circuit was connected to a phase shifter with an opposite phase to make a desired output phase. In the design example, a three-port 90-degree hybrid coupler was implemented on the IPD process to operate at the 6 GHz WIFI frequency. The post-simulation showed that all reflection coefficients were below −19 dB, with an insertion loss of 1.76 dB and isolation of 20 dB. The core chip size was only 0.02λ0 × 0.018λ0. Full article
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13 pages, 8235 KB  
Article
An Integrated Ultra-Wideband Balun Topology and Its Application in Mixer Design
by Xu Zhu, Hanzhong Xu, Bill Beckwith and Xudong Wang
Electronics 2025, 14(8), 1631; https://doi.org/10.3390/electronics14081631 - 17 Apr 2025
Cited by 2 | Viewed by 2136
Abstract
A compact ultra-wideband balun topology suitable for on-chip integration is introduced in this paper. The balun is designed using an inverting transformer for the generation of the inverted signal, and a third inductor is incorporated to support the generation of the non-inverted signal. [...] Read more.
A compact ultra-wideband balun topology suitable for on-chip integration is introduced in this paper. The balun is designed using an inverting transformer for the generation of the inverted signal, and a third inductor is incorporated to support the generation of the non-inverted signal. Through examining the transfer function and bandwidth limitations of existing on-chip voltage transformer and current transformer baluns, the broadband feature of the balun is clearly demonstrated through theoretical analysis and simulation, and further validated by a practical example. Measurement results confirm that a −3 dB relative bandwidth of approximately 167% is achieved, along with excellent amplitude and phase balance. The integrated ultra-wideband balun topology is also applied in a mixer design, resulting in a product with industry-leading RF and IF operating bandwidths. Full article
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11 pages, 7128 KB  
Article
An On-Chip Balun Using Planar Spiral Inductors Based on Glass Wafer-Level IPD Technology
by Jiang Qian, Peng Wu, Haiyang Quan, Wei Wang, Yong Wang, Shanshan Sun and Jingchao Xia
Micromachines 2025, 16(4), 443; https://doi.org/10.3390/mi16040443 - 9 Apr 2025
Viewed by 3515
Abstract
As integrated electronic microsystems advance, their internal components demonstrate increasing miniaturization, higher-density integration, and, consequently, significantly enhanced performance. This paper presents an on-chip transformer balun. The balun has a combination of planar coupled inductors and filtering capacitors using integrated passive device (IPD) technology, [...] Read more.
As integrated electronic microsystems advance, their internal components demonstrate increasing miniaturization, higher-density integration, and, consequently, significantly enhanced performance. This paper presents an on-chip transformer balun. The balun has a combination of planar coupled inductors and filtering capacitors using integrated passive device (IPD) technology, giving it the advantages of a more compact circuit size and lower cost to achieve single-ended to differential function on glass substrates. Moreover, it can be integrated in systems by flip-chip. The die has a size of 1.81 mm × 1.36 mm with a −15 dB single-ended return loss bandwidth of 2.07 GHz to 4.30 GHz. Within this bandwidth, the maximum insertion loss is 2.56 dB, and the amplitude imbalance is less than 2.04 dB. The phase difference between the differential signals is 180 ± 14.02° and the common mode rejection ratio (CMRR) is above 19.08 dB. The balun has the potential of miniaturization for integration on package or through-glass interposers (TGIs). Full article
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13 pages, 6578 KB  
Article
A Circularly Polarized Broadband Composite Spiral Antenna for Ground Penetrating Radar
by Hai Liu, Shangyang Zhang, Pei Wu, Xu Meng, Junyong Zhou and Yanliang Du
Sensors 2025, 25(6), 1890; https://doi.org/10.3390/s25061890 - 18 Mar 2025
Viewed by 2862
Abstract
To enhance the capability of a ground penetrating radar (GPR) in subsurface target identification and improve its polarization sensitivity in detecting underground linear objects, a circularly polarized broadband composite spiral antenna was designed. This antenna integrates equiangular spiral and Archimedean spiral structures, achieving [...] Read more.
To enhance the capability of a ground penetrating radar (GPR) in subsurface target identification and improve its polarization sensitivity in detecting underground linear objects, a circularly polarized broadband composite spiral antenna was designed. This antenna integrates equiangular spiral and Archimedean spiral structures, achieving a wideband coverage of 1–5 GHz with stable circular polarization characteristics. The antenna employs an exponentially tapered microstrip balun for impedance matching and a metallic-backed cavity filled with absorbing materials to enhance its directivity. Experimental results demonstrate excellent radiation performance and stable circular polarization characteristics, with the axial ratio consistently below 3 dB throughout the operating frequency band, highlighting its suitability for polarimetric GPR systems. Furthermore, a 3D GPR measurement using the designed antenna validates its improved capacity for detecting subsurface linear objects, compared to the conventional linearly polarized bowtie antenna. Full article
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18 pages, 5992 KB  
Article
A Deployable Conical Log Spiral Antenna for Small Spacecraft: Electronic Design and Test
by Lewis R. Williams, Karina Vieira Hoel, Lars Erling Bråten, Arthur Romeijer, Natanael Hjermann and Bendik Sagsveen
Aerospace 2025, 12(3), 218; https://doi.org/10.3390/aerospace12030218 - 7 Mar 2025
Cited by 1 | Viewed by 4116
Abstract
An ultra-high-frequency (UHF) deployable conical log spiral antenna’s design and experimental test results are presented. The antenna is a spring constructed from a carbon-fiber-infused epoxy matrix. The spring design simplified the spacecraft deployment mechanism, and the use of composite materials allowed for the [...] Read more.
An ultra-high-frequency (UHF) deployable conical log spiral antenna’s design and experimental test results are presented. The antenna is a spring constructed from a carbon-fiber-infused epoxy matrix. The spring design simplified the spacecraft deployment mechanism, and the use of composite materials allowed for the integration of radiating elements into the spring structure. A Chebyshev transformer at the base of the antenna is used to match the incoming transmission line impedance to a 95 Ω coaxial cable. The 95 Ω coaxial, which is the balun and the radiating element, is embedded into the antenna structure. The antenna is fed at the cone’s base without requiring a ground plane whilst maintaining radiation in the cone’s apex-pointing direction. This facilitated an uncomplicated deployment mechanism. Prototypes have been manufactured for 500 to 1500 MHz designs. Antenna measurements show a realized gain of between approximately 3 to 6 dBi from 500 to 1500 MHz. Full article
(This article belongs to the Special Issue Small Satellite Missions)
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10 pages, 2974 KB  
Article
A New Observation in Decoupling and Sequential Rotation Array Configurations Using Loop Radiation Elements
by Kazuhide Hirose, Koki Nishino and Hisamatsu Nakano
J 2025, 8(1), 9; https://doi.org/10.3390/j8010009 - 1 Mar 2025
Viewed by 1543
Abstract
Using the method of moments, we analyze three array antennas for low cross-polarized radiation. Each antenna comprises two dual-loop elements connected to a feedline horizontal to the ground plane. First, a feedline end is excited with an unbalanced source as a reference antenna. [...] Read more.
Using the method of moments, we analyze three array antennas for low cross-polarized radiation. Each antenna comprises two dual-loop elements connected to a feedline horizontal to the ground plane. First, a feedline end is excited with an unbalanced source as a reference antenna. Next, the feedline center is excited with a balanced source, after the transformation of a decoupling array configuration. It is found that the antenna exhibits a cross-polarized radiation lower by 12 dB than the reference antenna. Last, the decoupling antenna is modified to have an unbalanced source without a complicated balun circuit design. It is pointed out that the modified antenna is an array of four loop elements, sequentially rotated by 90º. Full article
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19 pages, 14789 KB  
Article
Mesenchymal Stem Cells with Simultaneous Overexpression of GPX3 and CD47 for the Treatment of Drug-Induced Acute Liver Injury
by Yuanxiang Jing, Balun Li, Aili Aierken, Zengyu Zhang, Dongyao Han, Zixi Lin, Jiaqi Gao, Hongkai Tian and Jinlian Hua
Vet. Sci. 2025, 12(2), 149; https://doi.org/10.3390/vetsci12020149 - 10 Feb 2025
Cited by 2 | Viewed by 2181
Abstract
The liver, as the largest metabolic and detoxification organ in mammals, metabolizes approximately 80–90% of drugs. However, drug-induced liver injury (DILI) is common and driven by factors such as individual variability, differences in liver metabolism, and improper drug use. Mesenchymal stem cells (MSCs), [...] Read more.
The liver, as the largest metabolic and detoxification organ in mammals, metabolizes approximately 80–90% of drugs. However, drug-induced liver injury (DILI) is common and driven by factors such as individual variability, differences in liver metabolism, and improper drug use. Mesenchymal stem cells (MSCs), with their self-renewal and multipotent differentiation capabilities, offer therapeutic potential, but face challenges such as limited proliferation and increased apoptosis during in vitro expansion. Although MSCs exhibit low immunogenicity, they are often cleared by the host immune system, which limits their survival and engraftment. Glutathione peroxidase 3 (GPX3) is a key antioxidant enzyme that reduces reactive oxygen species (ROS), protecting cells from oxidative damage. CD47, also known as integrin-associated protein (IAP), helps cells evade immune clearance by binding to signal regulatory protein alpha (SIRPα) on the immune cells. Here, we used an acetaminophen (APAP)-induced DILI mouse model to evaluate the therapeutic efficacy of intravenously infused MSCs overexpressing GPX3 and CD47. Compared to unmodified MSCs, modified MSCs showed improved survival, reduced liver inflammation, and alleviated oxidative damage, offering enhanced protection against APAP-induced DILI. Full article
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