304,121 Results Found

Objectives: The occurrence of cognitive deficits after subarachnoid hemorrhage (SAH) is highly possible, leading to vascular dementia. We performed a novel longitudinal genome-wide association study (GWAS) to identify genetic modifications associated...

Mucormycoses can be treated with the combination of Amphotericin B and Isavuconazole. This study evaluates the effects of these drugs in vitro against 59 strains representing 12 Mucorales. In vitro testing of the two drugs together and alone was perf...

The European Burns Association (EBA), as the proud owner of the European Burn Journal (EBJ), is committed to fostering collaboration and maximizing the impact of our common goals, i [...]

There has been great progress in Huntington’s disease (HD) research. Yet, effective treatments to halt disease before the onset of disabling symptoms are still unavailable. Scientific breakthroughs require an active and lasting commitment from famili...

VACTERL association (OMIM 192350) is a non-random combination of multiple congenital malformations including vertebral, anal, cardiac, tracheoesophageal, renal and limb anomalies. The wide spectrum of defects suggests the occurrence of defective deve...

Using the Lung Kong Association as a case study, this article explores the cultural and socio-religious significance of the clan association in overseas Chinese societies. It argues that the Chinese diaspora has continually endeavored to utilize Conf...

Benzo[a]pyrene is an important indicator of polycyclic aromatic hydrocarbons pollution that exhibits complex atmospheric dynamics influenced by meteorological factors and suspended particulate matter (SPM). Herein, the factors influencing B(a)P conce...

Background: This study aims to characterize the clinical features and outcomes of tattoo-associated sarcoid-like uveitis using a multicenter uveitis registry given the limited existing data. Design: This is a retrospective study. Participants: Ten pa...

VACTERL association is a rare malformation complex consisting of vertebral defects, anorectal malformation, cardiovascular defects, tracheoesophageal fistulae with esophageal atresia, renal malformation, and limb anomalies. According to current knowl...

Genome-wide association study (GWAS) of Juvenile idiopathic arthritis (JIA) suffers from low power due to limited sample size and the interpretation challenge due to most signals located in non-coding regions. Gene-level analysis could alleviate thes...

This study evaluated 290 recombinant inbred lines (RILs) from the Nested Association Mapping (NAM) population in the UK, consisting of 24 hybrid families. All genotypes were grown in Southeastern Kazakhstan (Kazakh Research Institute of Agriculture a...

The problem of data association for target tracking in a cluttered environment is discussed. In order to improve the real-time processing and accuracy of target tracking, based on a probabilistic data association algorithm, a novel data association a...

Several genome-wide association studies (GWASs) have reported the association between genetic variants and the habitual consumption of foods and drinks; however, no association data are available regarding the consumption of black tea. The present st...

This study aimed to analyze the performance factors of both Ladies Professional Golf Association (LPGA) and Korea Ladies Professional Golf Association (KLPGA) players and suggest which performance factors they should improve to play in world-level ga...

Ecological patterns of species distribution can reveal essential information on the spatial and functional relationship between species or species and their environment. Various approaches can be used to assess species associations, and our study aim...

The National Health Insurance (NHI) special health checkup system in Japan targets the NHI population aged 40–74 years. Since 2015, the Kagawa NHI special health checkup was initiated in a prefecture-wide chronic kidney disease (CKD) initiative, incl...

This paper focuses on obtaining the association rules between the symmetry of different mechanical structure layers and requirements through data mining, then suggests the selection of symmetry schemes under different requirement conditions, based on...

Since the completion of the Human Genome Project, the field of human genetics has been in great flux, largely due to technological advances in studying DNA sequence variation. Although community-wide adoption of statistical standards was key to the s...

A transcriptome-wide association study (TWAS) was conducted on genome-wide association study (GWAS) summary statistics of malignant melanoma of skin (UK Biobank dataset) and The Cancer Genome Atlas-Skin Cutaneous Melanoma (TCGA-SKCM) gene expression...

Grain protein content (GPC) is controlled by complex genetic systems and their interactions and is an important quality determinant for hard spring wheat as it has a positive effect on bread and pasta quality. GPC is variable among genotypes and stro...

Building accurate and compact classifiers in real-world applications is one of the crucial tasks in data mining nowadays. In this paper, we propose a new method that can reduce the number of class association rules produced by classical class associa...

Metabolic (dysfunction) associated fatty liver disease (MAFLD) is generally developed with excessive accumulation of lipids in the liver. Ketogenesis is an efficient pathway for the disposal of fatty acids in the liver and its metabolic benefits have...

Dyslipidemia is an important independent risk factor for cardiovascular disease (CVD). Specifically, apolipoprotein A1 (ApoA1), apolipoprotein B (ApoB), and the ApoB/A1 ratio have been linked to CVD. We conducted a genome-wide association study meta-...

Controversy around the association between celiac disease (CeD) and attention deficit hyperactive disorder (ADHD) was addressed by a systematic review in 2015, ultimately showing no association. Since 2015, there have been several studies showing an...

Telomeres are repetitive tandem DNA sequences that cap chromosomal ends protecting genomic DNA from enzymatic degradation. Telomeres progressively shorten with cellular replication and are therefore assumed to correlate with biological and chronologi...

The identification of target genes at genome-wide association study (GWAS) loci is a major obstacle for GWAS follow-up. To identify candidate target genes at the 16 known endometrial cancer GWAS risk loci, we performed HiChIP chromatin looping analys...

Background: Intraocular pressure (IOP) is a major modifiable risk factor for glaucoma. However, the mechanisms underlying the controlling of IOP remain to be elucidated. Objective: To prioritize genes that are pleiotropically associated with IOP. Met...

For automobile insurance, it has long been implied that when a policyholder made at least one claim in the prior year, the subsequent premium is likely to increase. When this happens, the policyholder may seek to switch to another insurance company t...

In today’s world, millions of transactions are connected to online businesses, and the main challenging task is ensuring the privacy of sensitive information. Sensitive association rules hiding (SARH) is an important goal of privacy protection...

Data association is a crucial component of multiple target tracking, in which each measurement obtained by the sensor can be determined whether it belongs to the target. However, many methods reported in the literature may not be able to ensure the a...

This study examined the association between developmental dysplasia of the hip (DDH) and disease-associated loci in a Japanese cohort. A genome-wide association study (GWAS) of 238 Japanese patients with DDH and 2044 healthy individuals was performed...

Currently, most multi-target data association methods require the assumption that the target motion model is known, but this assumption is clearly not valid in a real environment. In the case of an unknown system model, the influence of environmental...

Angiotensinogen (AGT) is one of the most significant enzymes of the renin-angiotensin-aldosterone system (RAAS) which is involved in the regulation and maintenance of blood pressure. AGT is involved in the production of angiotensin I which is then co...

The amount of water-accessible-surface-area, WASA, buried upon protein–protein association is a good measure of the non-covalent complex stability in water; however, the dependence of the binding Gibbs free energy change upon buried WASA proves...

Multiple genes within the DISC1 (Disrupted-in-Schizophrenia-1) interactome have been implicated in psychotic disorders, which are characterized by hallucinations, delusions, negative symptoms, and disorganized behavior. However, the genetic associati...

This paper summarizes the practical impact of the College of American Pathologists, the International Association for the Study of Lung Cancer, and the Association for Molecular Pathology lung cancer biomarkers guidelines on the lung cancer approach...

Ventilator-associated pneumonia (VAP) has significant effects on patient outcomes, including prolonging the duration of both mechanical ventilation and stay in the intensive care unit (ICU). The aim of this study was to assess the association between...

Due to sensor characteristics, geographical environment, electromagnetic interference, electromagnetic silence, information countermeasures, and other reasons, the phenomenon of track breakages occur in the process of aircraft track data processing....

The prevalence of cancer, diabetes mellitus (DM), and hypertension is increasing in ageing populations. We analyzed the association of DM with cancer and its effects on cancer mortality. The data of 2009–2018 from the Korea National Hospital Di...

Papillary thyroid cancer (PTC) is the most common type of thyroid malignancy with an increased female incidence ratio. The specific traits of X chromosome inheritance may be implicated in gender differences of PTC predisposition. The aim of this stud...

Heat and drought, individually or in combination, limit pea productivity. Fortunately, substantial genetic diversity exists in pea germplasm for traits related to abiotic stress resistance. Understanding the genetic basis of resistance could accelera...

Bullous pemphigoid (BP), the most prevalent autoimmune blistering skin disorder, has been associated with dipeptidyl peptidase-4 inhibitor (DPP4i) treatment in type 2 diabetic patients. This study aimed to investigate the association of DPP4 gene var...

Background: Metabolic dysfunction-associated steatotic liver disease (MALSD) is defined as the excessive accumulation of triglycerides in the liver in the presence of at least one cardiometabolic risk factor and liver biopsy remains the diagnostic go...

Background and Objectives: In recent years, bipolar disorder (BD), a multifaceted mood disorder marked by severe episodic mood fluctuations, has been shown to have an impact on disability-adjusted life years (DALYs). The increasing prevalence of BD h...

Association rule learning is a machine learning approach aiming to find substantial relations among attributes within one or more datasets. We address the main problem of this technology, which is the excessive computation time and the memory require...

Individuals suffering from sensitive skin often have other skin conditions and/or diseases, such as fair skin, freckles, rosacea, or atopic dermatitis. Genome-wide association studies (GWAS) have been performed for some of these conditions, but not f...

Small vessel strokes (SVS) and intracerebral haemorrhages (ICH) are acute outcomes of cerebral small vessel disease (SVD). Genetic studies combining both phenotypes have identified three loci associated with both traits. However, the genetic cis-regu...

Protein molecules associate in solution, often in clusters beyond pairwise, leading to liquid phase separations and high viscosities. It is often impractical to study these multi-protein systems by atomistic computer simulations, particularly in mult...

Computer communication via text messaging or Social Networking Services (SNS) has become increasingly popular. At this time, many studies are being conducted to analyze user information or opinions and recognize emotions by using a large amount of da...

Interrupted and multi-source track segment association (TSA) are two key challenges in target trajectory research within radar data processing. Traditional methods often rely on simplistic assumptions about target motion and statistical techniques fo...