Search Results (235)

Adolescence represents a critical period of neurodevelopment during which brain-derived neurotrophic factor (BDNF) plays a fundamental role in neuronal survival and synaptic plasticity. While exercise-BDNF relationships are well-documented in adults, evidence in adolescents remains limited and inconsistent. This systematic review examined the effects of exercise modalities on circulating BDNF concentrations in adolescent populations. A systematic search was conducted following PRISMA guidelines across multiple databases (FECYT, PubMed, SPORTDiscus, ProQuest Central, SCOPUS, Cochrane Library) through June 2025. Inclusion criteria comprised adolescents, exercise interventions, BDNF outcomes, and randomized controlled trial design. Methodological quality was assessed using the PEDro scale. From 130 initially identified articles, 8 randomized controlled trials were included, with 4 rated as excellent and the other 4 as good quality. Exercise modalities included aerobic, resistance, concurrent, high-intensity interval training, Taekwondo, and whole-body vibration, with durations ranging 6–24 weeks. Four studies demonstrated statistically significant BDNF increases following exercise interventions, four showed no significant changes, and one reported transient reduction. Positive outcomes occurred primarily with vigorous-intensity protocols implemented for a minimum of six weeks. Meta-analysis was not feasible due to high heterogeneity in populations, interventions, and control conditions. Moreover, variation in post-exercise sampling timing further limited comparability of BDNF results. Future research should standardize protocols and examine longer interventions to clarify exercise-BDNF relationships in adolescents. Full article

The present study aims to investigate the multi-year effects (5 years) of individualized whole-body vibration (WBV) on locomotion, postural control, and handgrip strength in a 68-year-old man with relapse remitting multiple sclerosis (PwRRMS). The dose–response relationship induced by a single session was quantified by determining the surface electromyographic activity (sEMG) of the participant. The participant wore an orthosis to limit the lack of foot dorsiflexion in the weakest limb during walking in daily life. The gait alteration during walking was assessed at 1, 2 and 3 km/h (without the orthosis) through angle–angle diagrams by quantifying the area, perimeter and shape of the loops, and the sEMG of leg muscles was recorded in both limbs. The evaluation of postural control was conducted during upright standing by quantifying the displacement of the center of pressure (CoP). The handgrip strength was assessed by measuring the force–time profile synchronized with the sEMG activity of upper arm muscles. The participant improved his ability to walk at higher speeds (2–3 km/h) without the orthosis. There were greater improvements in the area and perimeter of angle–angle diagrams for the weakest limb (Δ = 36–51%). The sEMG activity of the shank muscles increased at all speeds, particularly in the tibialis anterior of weakest limbs (Δ = 10–68%). The CoP displacement during upright standing decreased (Δ = 40–60%), whereas the handgrip strength increased (Δ = 32% average). Over the 5-year period of intervention, the individualized WBV improved locomotion, postural control and handgrip strength without side effects. Future studies should consider the possibility of implementing an individualized WBV in PwRRMS. Full article

Background: Whole-body vibration (WBV) favors central integration and elaboration of proprioceptive stimuli, enhancing gait performance in individuals with Parkinson’s disease (PD). However, the effect of WBV on spatiotemporal gait kinematics in PD has been neglecting so far. This study aims to examine how exposure to WBV could influence kinematic parameters in PD. Methods: Gait kinematic parameters of 26 mild-stage PD participants (age: 66.7 ± 1.63 years) were measured using BTS G-Walk sensor during a 10 m walk test under three conditions—WBV, half squat without vibration (HS), and control condition (CC)—in a crossover randomized design. Results: Walking time was significantly slower (p < 0.01) in CC compared to WBV and HS, while no significant differences were observed between WBV and HS. Right leg propulsion was significantly lower in CC compared to HS (p < 0.01), with no significant differences between CC and WBV. Left leg propulsion was significantly lower in CC and WBV compared to HS (p < 0.01 and p < 0.05, respectively). Pelvic tilt was significantly lower (p < 0.05) in CC compared to WBV and HS, but no significant difference was observed between WBV and HS. Cadence was significantly lower (p < 0.05) in CC and WBV than HS. Conclusions: WBV shows promising effects on functional mobility and postural control in PD, with HS offering greater benefits. Exercise modalities should be carefully selected to enhance different gait parameters. Full article

Introduction: Emerging evidence indicates that whole-body vibration (WBV) may be a relevant adjunct in interventions targeting overweight and obese individuals. Moreover, WBV has been applied in combination with other exercise modalities and therapeutic strategies, with various physiological responses observed in this population. Objective: The current systematic review aimed to assess the physiological effects of WBV with other modalities of exercises in overweight and obese individuals. Methods: Searches in PubMed, Embase, Web of Science, Scopus, and Cochrane databases were conducted to assess physiological responses to the combination of WBV with other modalities of exercises in overweight and obese individuals. Publications were identified and the screening was performed by two reviewers, independently. Irrelevant studies were excluded based on the eligibility criteria. Results: Seven studies, analyzing different outcomes, were included, with a mean methodological quality score of 7. Four studies analyzed the acute effect and three studied the cumulative effect, with different intervention protocols. Increases in growth hormone (GH) concentrations and bioelectrical phase angles, and reductions in fat mass, blood triglycerides, and cholesterol concentrations, as well as blood pressure, heart rate, and arterial stiffness, were reported. Conclusions: WBV combined with other exercise modalities seems to promote important physiological responses in overweight and obese individuals. However, more large-scale, long-term randomized controlled trials with WBV and other modalities of exercises in overweight and obese cohorts are needed to corroborate and expand the findings of the current systematic review. Full article

Background: This systematic review and meta-analysis aims to provide a detailed analysis of the current state of knowledge on Progressive Exercise Training (PET), encompassing its diverse modalities, effects on bone mineral density (BMD), quality of life outcomes, and implications for clinical practice. Methods: A structured search strategy was employed to retrieve literature from seven databases (PubMed, Web of Science, Scopus, MEDLINE, Science Direct, EBSCO, CINHAL, and PEDro) yielded twenty-four randomized controlled trials (RCTs) meeting the inclusion criteria. The methodological quality of studies was evaluated using the PEDro scale. Meta-analyses were carried out to comprehensively assess the collective impact of PET on bone mineral density outcomes. Results: PET exhibited favorable effects on BMD across multiple anatomical sites, encompassing the femoral neck, total hip, lumbar spine, and others. This effect was observed across different age groups and genders, highlighting its potential benefits for diverse populations. PET encompasses a range of modalities, including resistance training, aerobic training, impact training, whole-body vibration, and tai chi, with a duration ranging from 4 to 24 months, with weekly sessions varying from two to five times. Some studies combined these modalities, reflecting the adaptability of PET to individual preferences and capabilities. Tailoring exercise prescriptions to individual needs emerged as a feasible approach within PET. A subset of studies assessed quality of life using validated instruments such as the 36-item short form survey (SF-36), shortened osteoporosis quality of life questionnaire (SOQLQ), and menopause quality of life instrument (MENQOL). Conclusions: This study provides strong evidence that PET represents a promising intervention for osteoporosis management, enhancing BMD and, to some extent, quality of life. PET offers a beacon of hope for better skeletal health and well-being in individuals grappling with osteoporosis, emphasizing the need for its incorporation into clinical practice. Full article

This study evaluates the safety aspects of a prototype electric vehicle designed to enable wheelchair users to independently perform simple farm tasks in rural settings, like sample collection and crop monitoring. The vehicle, built at CREA, features four in-wheel electric motors, a pneumatic suspension system, and a secure wheelchair anchoring system. Tests at the CREA experimental farm assessed the vehicle’s whole-body vibrations on different surfaces (asphalt, headland, dirt road) using two tyre models and multiple speeds. A triaxial accelerometer on the wheelchair seat measured vibrations, which were analysed in accordance with ISO standards. Frequency analysis revealed significant vibrations in the 2–40 Hz range, with the Z-axis consistently showing the highest accelerations, which increased with the speed. Tyre A generally induced higher vibrations than Tyre B, likely due to the tread design. At high speeds, the effective accelerations exceeded safety thresholds on asphalt and headland. Statistical analysis confirmed speed as the dominant factor, with the surface type also playing a key role—headland generated the highest vibrations, followed by dirt road and asphalt. The results of these first tests highlighted the high potential of the vehicle to improve the agricultural mobility of disabled people, granting safety conditions and low vibration levels on all terrains at speeds up to 10 km h⁻¹. At higher speeds, however, the vibration levels may exceed the exposure limits, depending on the irregularities of the terrain and the tyre model. Overcoming these limitations is achievable through the optimization of the suspensions and tyres and will be the subject of the next step of this study. This technology could also support wheelchair users in construction, natural parks, and urban mobility. Full article

Knee osteoarthritis (KOA) is a growing health challenge with increasing prevalence. Early diagnosis and effective interventions are crucial to the management of KOA individuals. Vibration therapy has shown promise as an intervention for KOA. Systemic vibratory therapy (SVT) and local vibratory therapy (LVT) have gained interest in recent years. In these therapies, mechanical vibrations are transmitted to the body either systemically or locally. The current systematic review aims to comprehensively summarize SVT and LVT effects on the functional capacity of KOA individuals. Searches in PubMed, Web of Science, Scopus, PEDro, and EMBASE on 3 July 2024, including only randomized controlled trials, were performed. The data collected were participant characteristics, vibrating devices, intervention duration, and main findings. Risk of bias (RoB) was assessed with Cochrane tools, and methodological quality (MQ) was assessed via the Physiotherapy Evidence Database. Nine papers were selected from 922 articles: five on SVT and four on LVT, involving 352 individuals aged 40–80. SVT studies reported acute or chronic responses like increased muscle strength and improved functional capacity. LVT studies also indicated functional capacity improvements. RoB was classified as ‘high’ in three SVT studies and ‘low’ in two LVT studies. MQ was classified as ‘high’ in five SVT studies and one LVT study. Both SVT and LVT studies reported improvements in muscle strength, range of motion, and functional capacity. The current review revealed beneficial effects of both therapies on the functional capacity of KOA individuals. However, further well-designed studies are needed to reach definitive conclusions about the effect of SVT and LVT for KOA individuals. Full article

Background and Objectives: Whole-body vibration (WBV) therapy presents controversial evidence regarding its effectiveness in improving lower limb functional capacity in children with cerebral palsy (CP), particularly when applied continuously as an adjunct to a physiotherapy program with demonstrated efficacy. This study aimed to evaluate the effectiveness of adding WBV to an intensive therapeutic exercise and functional training program in improving lower limb functional capacity in children with spastic CP. Materials and Methods: Thirty children with spastic CP were randomly assigned to a control or experimental group. Both groups completed a 4-week intensive therapeutic exercise and functional training program (4 sessions/week). The experimental group additionally received daily WBV. Results: Both groups showed significant improvements in all analysed variables at 1, 2, and 6 months post-treatment (p < 0.001). However, no significant between-group differences were found for primary (GMFM-88 D: p = 0.80; GMFM-88 E: p = 0.91) or secondary outcomes in relation to muscle tone and strength, and balance. A trend toward greater improvement was observed in the experimental group but without statistical significance. Conclusions: The addition of WBV to an intensive program of therapeutic exercise and functional training does not yield additional benefits in motor function, spasticity, gait capacity, lower limb muscle strength, or balance compared to intensive physiotherapy and functional training alone in children with spastic CP. The significant within-group improvements can be attributed to the intensive physiotherapy intervention, comprising therapeutic exercises and functional training. Full article

Winch-assisted harvesting has expanded considerably in recent years as it enables ground-based machines to work safely on steep slopes. To analyze operator exposure to whole-body and hand–arm vibration (WBV, HAV) and noise exposure (LA_eq, LC_peak) during winch-assisted harvesting (TW) and harvesting without winch assistance (NTW), a field study using a Ponsse Scorpion King harvester and an Ecoforst T-winch traction winch was conducted. Vibrations were measured at three locations inside the cabin (seat, seat base/floor, control lever), while noise exposure was recorded both inside and outside the cabin. WBV exposure during work time operations was highest in the Y-direction, both on the seat (0.49–0.87 m/s²) and on the floor (0.41–0.84 m/s²). The WBV and HAV exposure levels were highest while driving on the forest and skid road. Exposure during the main productive time was significantly influenced by the harvesting system, diameter at breast height (DBH), and tree species. Noise exposure was higher, while WBV and HAV exposures on the seat, floor and control lever were lower during non-work time than during work time. The daily vibration exposure on the seat exceeded the EU action value, while LC_peak noise exposure surpassed the limit value of 140 dB(C) on all measured days. Noise and vibration exposure were constantly higher during TW than NTW harvesting but differences were small. Compared to other studies, the results show that harvesting on steep terrain increases noise and vibration exposure, while non-work time has the opposite effect on vibration and noise exposure. Full article

Background/Objectives: After spinal cord injury (SCI), poor dorsiflexor control and involuntary plantar-flexor contraction impair walking. As whole-body vibration (WBV) improves voluntary muscle activation and modulates reflex excitability, it may improve ankle control. In this study, the dosage effects of WBV on walking speed, dorsiflexion, and spinal reflex excitability were examined. Methods: Sixteen people with chronic motor-incomplete SCI participated in this randomized sham-control wash-in study. Two weeks of sham stimulation (wash-in phase) were followed by either 2 weeks of eight repetitions (short bout) or sixteen repetitions of WBV (long bout; intervention phase) per session. Walking speed, ankle angle at mid-swing, and low-frequency depression of the soleus H-reflex were measured before and after the wash-in phase and before and after the intervention phase. Results: A significant dosage effect of WBV was not observed on any of the measures of interest. There were no between-phase or within-phase differences in ankle angle during the swing phase or in low-frequency depression. When dosage groups were pooled together, there was a significant change in walking speed during the intervention phase (mean = 0.04 m/s, standard deviation = 0.06, p = 0.02). There was not a significant correlation between overall change in walking speed and dorsiflexion angle or low-frequency depression during the study. Conclusions: Whole-body vibration did not have a dosage-dependent effect on dorsiflexion during the swing phase or on spinal reflex excitability. Future studies assessing the role of corticospinal tract (CST) descending drive on increased dorsiflexor ability and walking speed are warranted. Full article

Whole-body vibration (WBV) exposure presents occupational health risks across multiple industries, particularly in tasks involving heavy machinery and prolonged seating. This study examines WBV risk factors, intervention strategies, and the potential for digital monitoring solutions to strengthen workplace safety. A sector-wide analysis assessed vibration exposure levels, worker-reported discomfort, and the effectiveness of the existing control measures. The study introduces a conceptual framework for a mobile application designed to integrate real-time exposure tracking, structured worker feedback, and predictive risk assessment. The findings confirm that WBV exposure varies across industries, with the energy and maritime logistics sectors showing the highest levels of noncompliance. A tiered intervention strategy, classified by impact and effort, provides a structured method for prioritizing risk reduction measures. Immediate actions, such as real-time monitoring and preventive maintenance, require minimal effort but provide high-impact benefits, while long-term strategies, including ergonomic workstation redesign, demand greater investment but contribute to sustained exposure reduction. The proposed framework offers a scalable, data-driven approach to WBV risk management, transitioning workplace safety from compliance-based monitoring to proactive prevention. Future research should explore implementation feasibility, worker adoption, and the integration of AI-driven safety recommendations to support continuous improvements in workplace safety strategies. Full article

Background/Objectives: Work-related musculoskeletal disorders (WMSDs) have been found to be the leading factor in disabilities and absenteeism among workers. Despite their growing numbers, WMSD prevalence and risk factors among food delivery riders remain underexplored. Given the high WMSD prevalence among motorcyclists and the rising road traffic accidents (RTAs) among delivery riders in Malaysia, a cross-sectional study was conducted to identify the determinants of WMSDs among this neglected group. Methods: A self-reported questionnaire consisting of sociodemographic factors, work-related factors, and a validated Malay-translated Standardised Nordic Musculoskeletal Questionnaire (M-SNMQ) was used to evaluate the WMSD symptoms and related factors among 191 food delivery riders in Eastern Peninsular Malaysia. An ergonomic risk assessment using the Rapid Entire Body Assessment (REBA) method and whole-body vibration (WBV) measurement was also conducted to elicit the WMSD risk and vibration exposure among the riders. The determinants of WMSDs were analysed using multiple logistic regression using SPSS 20.4. Results: This study revealed a high prevalence of WMSDs (74.9%) among food delivery riders in Eastern Peninsular Malaysia. Furthermore, three factors were found to be significantly associated with WMSDs among riders, namely the increasing average working days (aOR = 2.00; 95% CI = 1.34, 2.98; p = 0.001), whole-body vibration (WBV) above the exposure action value (EAV) limit (aOR = 2.71; 95% CI = 1.13, 6.53; p = 0.026), and not exercising before work (aOR = 21.63; 95% CI = 7.45, 62.79; p < 0.001). Conclusions: Targeted interventions are essential to mitigate ergonomic risks and enhance rider safety. Occupational health policies should prioritise pre-work exercise and WBV exposure reduction to minimise musculoskeletal strain. Future longitudinal studies are needed to evaluate the long-term impact of these risks on riders’ health. Full article

In this article, an attempt was made to model the body of a person moving in a passive manner (movement forced by another person) in a wheelchair. For this purpose, the Wan–Schimmels model was modified by 4 DOF, supplementing it with the weight of the wheelchair and a polyurethane cushion. The study was designed to test the effectiveness of utilizing a polyurethane cushion to reduce the whole-body vibration acting on a person while moving in a wheelchair. The study used a rheological model of polyurethane (PU) foam with concentrated parameters. Harmonic and random vibration analysis was carried out for this model. At the same time, the model with 5 DOF seems to be sufficient to describe vibrations transmitted to wheelchair users. The model presented in this paper can become a tool for future analysis of vibrations of people of different weights, moving passively on various types of wheelchairs on surfaces whose irregularities can be given by an appropriate form of kinematic excitation. The approach used in this study is likely to be useful in selecting a wheelchair and seat cushion so as to counteract and minimize vibrations perceived by humans. Full article

This paper presents whole-body vibration prediction in an agricultural tractor based on selected operational parameters using machine learning. Experiments were performed using a Landini Powerfarm 100 model tractor on farmlands and service roads located at the Osijek School of Agriculture and Veterinary Medicine. The methodology adhered to the HRN ISO 5008 protocols for establishing test surfaces, including a smooth 100 m track and a rugged 35 m track. Whole-body vibrational exposure assessments were carried out in alignment with the HRN ISO 2631-1 and HRN ISO 2631-4 guidelines, which outline procedures for evaluating mechanical oscillations in occupational settings. The obtained whole-body vibration data were divided into three datasets (one for each axis) and processed using linear regression as a baseline and compared against three machine learning models (gradient boosting regressor; support vector machine regressor; multi-layer perception). The most accurate machine learning model according to the R² metric was the gradient boosting regressor for the x-axis (R²: 0.98) and the y-axis (R²: 0.98), and for the z-axis (R²: 0.95), the most accurate machine learning model was the SVM regressor. The application of machine learning methods indicates that machine learning models can be used to predict whole-body vibrations more accurately than linear regression. Full article

Promoting alternative modes of transportation such as cycling represents a valuable strategy to minimize environmental impacts, as confirmed in the main targets set out by the European Commission. In this regard, in cities throughout the world, there has been a significant increase in the construction of bicycle paths in recent years, requiring effective maintenance strategies to preserve their service levels. The continuous monitoring of road networks is required to ensure the timely scheduling of optimal maintenance activities. This involves regular inspections of the road surface, but there are currently no automated systems for monitoring cycle paths. In this study, an integrated monitoring and assessment system for cycle paths was developed exploiting Raspberry Pi technologies. In more detail, a low-cost Inertial Measurement Unit (IMU), a Global Positioning System (GPS) module, a magnetic Hall Effect sensor, a camera module, and an ultrasonic distance sensor were connected to a Raspberry Pi 4 Model B. The novel system was mounted on a e-bike as a test vehicle to monitor the road conditions of various sections of cycle paths in Rome, characterized by different pavement types and decay levels as detected using the whole-body vibration $a_{wz}$ index (ISO 2631 standard). Repeated testing confirmed the system’s reliability by assigning the same vibration comfort class in 74% of the cases and an adjacent one in 26%, with an average difference of 0.25 m/s², underscoring its stability and reproducibility. Data post-processing was also focused on integrating user comfort perception with image data, and it revealed anomaly detections represented by numerical acceleration spikes. Additionally, data positioning was successfully implemented. Finally, $a_{wz}$ measurements with GPS coordinates and images were incorporated into a Geographic Information System (GIS) to develop a database that supports the efficient and comprehensive management of surface conditions. The proposed system can be considered as a valuable tool to assess the pavement conditions of cycle paths in order to implement preventive maintenance strategies within budget constraints. Full article