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Review

18 Citations

4,856 Views

13 Pages

T-Type Calcium Channels: A Potential Novel Target in Melanoma

Carla Barceló,
Pol Sisó,
Oscar Maiques,
Inés de la Rosa,
Rosa M. Martí and
Anna Macià

Cancers2020, 12(2), 391;https://doi.org/10.3390/cancers12020391

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8 February 2020

T-type calcium channels (TTCCs) are overexpressed in several cancers. In this review, we summarize the recent advances and new insights into TTCC biology, tumor progression, and prognosis biomarker and therapeutic potential in the melanoma field. We...

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Review

16 Citations

5,684 Views

23 Pages

Voltage-Gated T-Type Calcium Channel Modulation by Kinases and Phosphatases: The Old Ones, the New Ones, and the Missing Ones

Ankush Sharma,
Ghazala Rahman,
Julia Gorelik and
Anamika Bhargava

Cells2023, 12(3), 461;https://doi.org/10.3390/cells12030461

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31 January 2023

Calcium (Ca2+) can regulate a wide variety of cellular fates, such as proliferation, apoptosis, and autophagy. More importantly, changes in the intracellular Ca2+ level can modulate signaling pathways that control a broad range of physiological as we...

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