You are currently on the new version of our website. Access the old version .

4 Results Found

  • Article
  • Open Access
1 Citations
898 Views
15 Pages

27 October 2025

Background/Objectives: Acute respiratory infections remain a major global public health concern affecting individuals across all ages. Accurate and rapid diagnosis of respiratory pathogens is crucial for effective patient management and infection con...

  • Article
  • Open Access
7 Citations
2,286 Views
11 Pages

30 August 2023

Background: Recently, panel-based molecular diagnostics for the simultaneous detection of respiratory viruses and bacteria in nasopharyngeal swab (NPS) specimens have been highlighted. We identified the distribution of bacterial species in NPS specim...

  • Article
  • Open Access
7 Citations
2,708 Views
12 Pages

Detection of SARS-CoV-2 Variants via Different Diagnostics Assays Based on Single-Nucleotide Polymorphism Analysis

  • Eliana Specchiarello,
  • Giulia Matusali,
  • Fabrizio Carletti,
  • Cesare Ernesto Maria Gruber,
  • Lavinia Fabeni,
  • Claudia Minosse,
  • Emanuela Giombini,
  • Martina Rueca,
  • Fabrizio Maggi and
  • Anna Rosa Garbuglia

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is characterized by fast evolution with the appearance of several variants. Next-Generation Sequencing (NGS) technology is considered the gold standard for monitoring known and new SARS-CoV...

  • Case Report
  • Open Access
13 Citations
3,560 Views
6 Pages

First Case of a COVID-19 Patient Infected by Delta AY.4 with a Rare Deletion Leading to a N Gene Target Failure by a Specific Real Time PCR Assay: Novel Omicron VOC Might Be Doing Similar Scenario?

  • Mohammad Alkhatib,
  • Maria Concetta Bellocchi,
  • Greta Marchegiani,
  • Sandro Grelli,
  • Valeria Micheli,
  • Daniele Stella,
  • Bartolomeo Zerillo,
  • Luca Carioti,
  • Valentina Svicher and
  • Francesca Ceccherini-Silberstein

Herein, we report a case of an Italian male infected by Delta sublineage AY.4 harboring an atypical deletion, leading to a N gene target failure (NGTF) by a commercial molecular assay for SARS-CoV-2 diagnosis (AllplexTM SARS-CoV-2 Assay, Seegene). A...