Search Results (6,702)

We investigated respiratory virus epidemiology in older adults across pre-pandemic (2007–2019), pandemic (2020–2022), and post-pandemic (2023–2024) periods, focusing on how public health interventions shaped surveillance, prevalence, and sex-specific trends. We conducted a retrospective cross-sectional study at a 1000-bed tertiary hospital in the Republic of Korea during 2007–2024, analyzing 4692 nasopharyngeal swab specimens collected from adults aged ≥ 65 years with suspected respiratory infections during 2007–2024. The specimens were tested for 15 respiratory viruses using multiplex real-time polymerase chain reaction. The outcomes included virus-specific detection rates and seasonal, sex-based and temporal trends before and after the COVID-19 pandemic. During the pre-pandemic period, older adults accounted for 13.2% of the tested individuals, which significantly increased to 52.0% in the later periods. Influenza A was the most frequently detected virus, followed by rhinovirus and human metapneumovirus. Influenza, RSV A/B, and coronaviruses 229E and OC43 showed peak positivity in winter, parainfluenza virus type 3 peaked in summer, and rhinovirus circulated year-round. Virus circulation was markedly suppressed during 2020–2022 and partially rebounded during 2023–2024. This study highlights the shift in diagnostic access and epidemiologic patterns of respiratory virus infections in older adults following the COVID-19 pandemic. Full article

The increasing demand for high-quality geospatial visualizations in scientific publications has highlighted the need for accessible and standardized tools that support reproducible research. Researchers from various disciplines—often without expertise in Geographic Information Systems (GIS)—frequently require a map figure to locate their study area. This paper presents the Study Area Map Generator, a web-based application developed using Shiny for Python, designed to automate the creation of country- and city-level study area maps. The tool integrates geospatial data processing, cartographic rendering, and user-friendly customization features within a browser-based interface. It enables users—regardless of GIS proficiency—to generate publication-ready maps with customizable titles, basemaps, and inset views. A usability survey involving 92 participants from diverse professional and geographic-based backgrounds revealed high levels of satisfaction, ease of use, and perceived usefulness, with no significant differences across GIS experience levels. The application has already been adopted in academic and policy contexts, particularly in low-resource settings, demonstrating its potential to democratize access to cartographic tools. By aligning with open science principles and supporting reproducible workflows, the Study Area Map Generator contributes to more equitable and efficient scientific communication. The application is freely available online. Future developments include support for subnational units, thematic overlays, multilingual interfaces, and enhanced export options. Full article

Creative insight is a core phenomenon of human cognition, often characterized by the sudden emergence of novel and contextually appropriate ideas. Classical models based on symbolic search or associative networks struggle to capture the non-linear, context-sensitive, and interference-driven aspects of insight. In this work, we propose a computational model of insight generation grounded in continuous-time quantum walks over weighted semantic graphs, where nodes represent conceptual units and edges encode associative relationships. By exploiting the principles of quantum superposition and interference, the model enables the probabilistic amplification of semantically distant but contextually relevant concepts, providing a plausible account of non-local transitions in thought. The model is implemented using standard Python 3.10 libraries and is available both as an interactive fully reproducible Google Colab notebook and a public repository with code and derived datasets. Comparative experiments on ConceptNet-derived subgraphs, including the Candle Problem, 20 Remote Associates Test triads, and Alternative Uses, show that, relative to classical diffusion, quantum walks concentrate more probability on correct targets (higher AUC and peaks reached earlier) and, in open-ended settings, explore more broadly and deeply (higher entropy and coverage, larger expected radius, and faster access to distant regions). These findings are robust under normalized generators and a common time normalization, align with our formal conditions for transient interference-driven amplification, and support quantum-like dynamics as a principled process model for key features of insight. Full article

Digital transformation has fundamentally altered how individuals manage their finances. The expansion of financial technologies and the digitalization of banking services underscore the need for digital financial literacy, defined as the ability to safely use financial applications and make informed decisions within virtual environments. This study examined the perceptions of financial application use across age groups and their corresponding level of digital financial literacy. This exploratory study used a convenience sample of 41 semi-structured interviews conducted in 2025. The data were analyzed using content analysis and descriptive statistics. The findings indicated that most participants prioritized digital apps over traditional channels and expressed confidence in their use, although concerns about data security remained. Participants identified key advantages, including convenience, efficiency, and centralized access, yet few used apps for financial planning. Most respondents demonstrated an intermediate level of digital knowledge, with limited proficiency in executing complex financial tasks. Perceptions revealed both optimism and apprehension: while participants valued the practicality of digital tools, they also recognized risks such as fraud, exclusion of vulnerable groups, and technological dependence. The limited and non-representative sample limits generalization, suggesting the need for broader surveys. Enhanced public policies promoting digital financial education in Brazil are recommended. Full article

Introduction: Tuberculosis (TB) remains a public health concern, and people at risk for TB are hesitant to seek care. The first South African National TB prevalence survey, conducted in 2017–2019, found that most participants with TB symptoms did not seek care for TB. In 2022, an estimated 23% of people with TB in South Africa were undiagnosed, contributing to the country’s burden of “missing” TB cases. This study explores health-seeking behaviour among people with TB (PwTB) in South Africa, focussing on barriers and facilitators to care-seeking and the quantification of TB-related stigma from a patient and community perspective. Methods: We conducted a mixed-method study in the City of Johannesburg (COJ) Metropolitan Municipality from February to March 2022. PwTB aged 18 and older initiating TB treatment for microbiologically confirmed pulmonary TB were recruited from three primary healthcare facilities in the COJ. After providing written informed consent, they participated in a one-time, in-depth, face-to-face interview. The interviews were digitally recorded and conducted by trained facilitators. We used thematic analysis with deductive approaches to develop themes. We used the Van Rie TB stigma assessment scale to quantify perceived stigma. Results: We interviewed 23 PwTB with an overall median age of 39 years and 14 (61%) males. Patient-level barriers to accessing TB care included visiting traditional healers and pharmacists before their TB diagnosis; wrong or missed diagnosis by private doctors; work commitments; scarcity of resources to attend the clinic or walk long distances; perceived and experienced stigma; and a lack of TB knowledge. Facility-level barriers included long clinic queues and uncertainty about where to receive TB care in the clinic. Facilitators for TB care-seeking included being in contact with someone who had TB, receiving encouragement from family, or having knowledge about TB transmission and early diagnosis. The overall median total stigma score among 21 PwTB was 53 (IQR: 46–63), with median community and patient stigma scores of 25 (IQR: 22–30) and 31 (IQR: 21–36), respectively. Conclusions: We found important considerations for the TB programme to improve the uptake of services. Since PwTB consult elsewhere before visiting a facility for TB care, TB programmes could establish private–public partnerships. TB programmes could also increase TB awareness in the community, especially among males, and mobile clinics could be considered to assist with TB case detection and treatment provision. Applying behavioural design techniques and co-designing interventions with patients and providers could improve TB health-seeking behaviours. Full article

Introduction: YouTube™ is a widely accessible platform with unfiltered medical information. This study aimed to evaluate the educational value and reliability of YouTube™ videos on Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for advanced epithelial ovarian cancer treatment. Methods: YouTube™ videos were searched using the keywords “ovarian cancer”, “debulking surgery”, “hyperthermic”, and “HIPEC”. Patient Education Materials Assessment Tool for Audiovisual Content (PEMAT A/V) score, DISCERN, Misinformation Scale, and the Global Quality Scale (GQS) were employed to assess the clarity, quality, and reliability of the information presented. Results: Of the 150 YouTube™ videos screened, 71 were suitable for analysis and categorized by target audience (general public vs. healthcare workers). Most (57, 80.2%) were uploaded after the “Ov-HIPEC” trial (18 January 2018), with a trend toward more videos for healthcare workers (p = 0.07). Videos for the general public were shorter (p < 0.001) but received more views (p = 0.06) and likes (p = 0.09), though they were of lower quality. The DISCERN score averaged 50 (IQR: 35–60), with public-targeted videos being less informative (p < 0.001), a trend mirrored by the Misinformation Scale (p < 0.001) and GQS (p < 0.001). The PEMAT A/V scores showed 80% Understandability (IQR: 62–90) and 33% Actionability (IQR: 25–100), with no significant difference between groups (p = 0.15, p = 0.4). Conclusions: While YouTube™ provides useful information for healthcare professionals, it cannot be considered a reliable source for patients seeking information on HIPEC for ovarian cancer. Many videos contribute to misinformation by not properly explaining treatment indications, timing, adverse effects, multimodal approaches, or clinical trial findings. Full article

Objectives: Narratives related to root canal treatment on social media can be problematic. This research examines discourses relating to root canal treatment on the popular platform Instagram. Through this analysis, the way different health discourses relating to endodontics are being communicated to the public and consumers will be explored. Methods: A search was conducted on Instagram to access consumer-focused information related to root canal treatment. Posts were identified, transcribed to capture the audio component in text form, and watched cyclically, with analytical memos being kept on video content. A social semiotic analysis was conducted on posts to capture the multimodal nature of discourse on endodontics. Results: A total of 100 Instagram posts were included in this study. Two overarching themes were used to structure the analysis of posts: (1) presentation of root canal treatment and (2) presentation of expertise. The majority of posts were negative in tone towards root canal treatment. Conclusions: The variety and nature of the misinformation featured in this research present a complex professional challenge for dentistry. The majority of the posts identified and analysed featured sensationalised explanations of dental disease and treatment processes, blended with inaccuracies, many of which were produced by dentists. Conspiracy discourses relating to root canal treatment were also encountered, which questioned the integrity and intentions of the dental profession. Full article

Breast cancer remains a leading cause of global cancer burden, with marked differences in incidence across countries. While biological risk factors are well established, understanding the broader structural and sociocultural influences has been less comprehensive. In this study, we analyzed harmonized data from 183 countries (2017–2023), encompassing 33 variables and 7 subvariables related to demographics, nutrition, environment, health, and healthcare access, drawn from open-access international databases. Spearman correlation analysis identified strong positive associations between breast cancer incidence and discontinued breastfeeding, high LDL cholesterol, out-of-pocket healthcare expenditure, and educational attainment. Conversely, poor sanitation, lack of handwashing facilities, unsafe water, and certain nutritional deficiencies exhibited robust negative correlations, likely reflecting under detection and reporting limitations in lower-resource settings rather than true protective effects. These findings were further explored using multiple linear regression, which explained approximately 73% of the variance in global breast cancer incidence. The final model highlighted discontinued breastfeeding, prevalence of cocaine use, unsafe sanitation, high out-of-pocket healthcare expenditure, limited handwashing access, and high processed meat consumption as the most influential independent predictors. Receiver operating characteristic (ROC) analysis confirmed strong predictive value for discontinued breastfeeding and out-of-pocket expenditure, with sanitation and hygiene variables showing paradoxical inverse associations. Our results emphasize that breast cancer risk is shaped not only by individual behaviors and genetics, but also by larger-scale structural, socioeconomic, and environmental factors. These patterns suggest that targeted interventions addressing both lifestyle behaviors and systemic inequities—such as promoting breastfeeding, reducing financial barriers to healthcare, and strengthening public health infrastructure—could meaningfully reduce the global burden of breast cancer. In conclusion, this study underscores the importance of multisectoral, equity-focused prevention strategies. It also highlights the value of country-level ecological analyses in uncovering upstream determinants of cancer incidence and calls for further research to disentangle individual and contextual effects in cancer epidemiology. Full article

Between 2020 and 2024, museums underwent accelerated digital transformation driven by the global health crisis and technological advances, exposing deep inequalities in access to technology and communication capabilities. Museums with limited resources had to rethink their digital strategies to sustain audience engagement and cultural relevance. This article presents a comparative study of museums in Argentina and Spain with restricted budgets, analyzing how they responded to challenges of uncertainty and scarcity. Using a mixed methodology—surveys of 22 professionals, interviews with directors of four representative museums, and qualitative case studies—this study examines the implemented solutions and their impacts. The findings highlight innovative practices grounded in creativity, strategic alliances, and intensive use of social media. Argentine museums excelled in tactical adaptation amid economic instability, while Spanish institutions showed stronger strategic planning. Private museums proved more flexible than their public counterparts, which faced greater bureaucratic constraints. This work contributes to debates on institutional resilience and offers a framework for sustainable digital communication in resource-limited contexts. Full article

Urban mobility plays a vital role in shaping sustainable cities, yet the effectiveness of public transportation is often undermined by poor last-mile connectivity (LMC). In the National Capital Region (NCR) of Delhi, despite the Delhi Metro Rail serving as a key transit system, limited integration with surrounding areas hinders accessibility, which particularly affects women, elderly adults, and socioeconomically disadvantaged groups. This study evaluates LMC performance at two key metro stations, Nehru Place and Botanical Garden, using a mixed-methods approach that includes user surveys, spatial survey, thematic analysis, and infrastructure scoring across five critical pillars: accessibility, safety and comfort, intermodality, service availability, and inclusivity. The findings communicate notable contrasts. Botanical Garden exhibits strong intermodal linkages, pedestrian-friendly design, and supportive signage, while Nehru Place indicates a need for infrastructural improvements, safety advancement and upgrades, and strengthened universal design features. These disparities limit effective metro usage and discourage a shift from private to public transport. The study highlights the importance of user-centered, multimodal solutions and the need for cohesive urban governance to address LMC gaps. By identifying barriers and opportunities for improvement, this research paper contributes to the formulation of more inclusive and sustainable urban transport strategies in Indian metropolitan regions. Full article

This study investigates the evolution of cybercrime in Greece by analyzing data from the Cyber Crime Division of the Hellenic Police. By combining 2023 statistics with earlier national and international data (e.g., Europol, FBI), this study presents a comprehensive 15-year view of cybercrime trends. Key findings highlight a persistent rise in cyber incidents, with financial fraud as the most common type. Other major threats include unauthorized system access, data breaches, and crimes targeting vulnerable populations. The study assesses national legislation aligned with EU directives and outlines stakeholder roles. It underscores the need for adaptive legal frameworks, inter-agency cooperation, and public awareness to mitigate Greece’s growing cybersecurity challenges. Full article

Despite being a preventable disease, cervical cancer remains a significant public health concern in low- and middle-income countries, including those in Latin America (LATAM), where mortality rates are nearly three times higher than in North America. HPV vaccination represents one of the most important strategies for cervical cancer elimination; however, uptake in these regions has been consistently suboptimal. The aim of this review is to analyze the current status of HPV vaccination programs across LATAM, examines the underlying challenges, and proposes strategies to enhance vaccine coverage. Multiple obstacles to widespread vaccine adoption persist, including limited awareness, cultural stigma, and regional disparities in healthcare access, often driven by socioeconomic and infrastructural limitations. Addressing these challenges through multifaceted interventions—such as school-based vaccination programs, healthcare provider engagement, digital dissemination, simplified dosing schedules, and supportive policy measures—is essential to effectively improve vaccination rates and reduce disease burden. Full article

As governments increasingly explore digital financial instruments to diversify funding channels and expand citizen participation, Thailand’s G-Token represents an early attempt to integrate blockchain technology into sovereign debt issuance. This study examines its potential implications through a multi-dimensional risk and governance framework, situating the analysis within both domestic regulatory structures and international benchmarks. The evaluation considers macroeconomic effects—such as potential shifts in monetary policy transmission, bank disintermediation risks, and systemic liquidity impacts—alongside micro-level concerns involving investor protection, market integrity, and financial literacy. Using comparative analysis with the European Union, Singapore, and United States regulatory approaches, the paper identifies critical gaps in legal classification, oversight maturity, and structural safeguards. Findings indicate that while Thailand’s design—particularly its separation from payment systems—supports monetary coherence, its ad hoc legal integration, reliance on administrative investor protections, and early-stage market infrastructure pose vulnerabilities if adoption scales. The study concludes that achieving long-term viability will require explicit statutory authorization, enhanced disclosure and governance standards, strengthened interagency oversight, and inclusive market access strategies. These insights provide a structured basis for emerging economies seeking to adopt government-backed tokenized instruments without undermining financial stability or public trust. Full article

Spatial accessibility is a key principle in urban studies, shaping how people reach amenities and services across cities. While most research concentrates on large metropolitan areas and central urban services, small and medium-sized cities and their main amenities remain less studied. To bridge this gap, this study explores spatial accessibility to public amenities in relation to population density in Odense, a medium-sized city known for its compact layout and robust infrastructure supporting walking, cycling, and public transport. Despite Odense’s proactive planning and multimodal transport network, marked accessibility inequalities still exist, especially in peripheral neighbourhoods. This research uses a data-driven approach combining network-based travel time analysis with grid-cell-based spatial visualisation. Additionally, a multi-criteria accessibility scoring framework is introduced, including indicators such as amenity density, diversity of services, temporal thresholds for walking and cycling, and population distribution. The results show an uneven accessibility landscape, with significant gaps in outer districts, highlighting the limitations of uniform planning thresholds. By applying spatial analytical principles, the study uncovers embedded socio-spatial inequalities in everyday urban access. These insights offer practical guidance for planners and policymakers, underscoring the importance of context-sensitive multimodal infrastructure and decentralised service provision to support sustainable urban growth. Full article

The recent growth of generative artificial intelligence (AI) has brought new possibilities and revolutionary applications in many fields. It has also, however, created important ethical and security issues, especially with the abusive use of deepfakes, which are artificial media that can propagate very realistic but false information. This paper provides an extensive bibliometric, statistical, and trend analysis of deepfake research in the age of generative AI. Utilizing the Web of Science (WoS) database for the years 2014–2024, the research identifies key authors, influential publications, collaboration networks, and leading institutions. Biblioshiny (Bibliometrix R package, University of Naples Federico II, Naples, Italy) and VOSviewer (version 1.6.20, Centre for Science and Technology Studies, Leiden University, Leiden, The Netherlands) are utilized in the research for mapping the science production, theme development, and geographical distribution. The cutoff point of ten keyword frequencies by occurrence was applied to the data for relevance. This study aims to provide a comprehensive snapshot of the research status, identify gaps in the knowledge, and direct upcoming studies in the creation, detection, and mitigation of deepfakes. The study is intended to help researchers, developers, and policymakers understand the trajectory and impact of deepfake technology, supporting innovation and governance strategies. The findings highlight a strong average annual growth rate of 61.94% in publications between 2014 and 2024, with China, the United States, and India as leading contributors, IEEE Access among the most influential sources, and three dominant clusters emerging around disinformation, generative models, and detection methods. Full article