Search Results (17)

This article addresses the question of love’s unconditionality. Drawing mainly on Husserl, Scheler, Arendt, and Patočka, it shows how love is both ubiquitous and unnecessary. There is no limit to what can be loved, but equally, all things can be related to without love. Love is at once unnecessary and yet constitutive of relations. It is shown that this peculiar characteristic of love is indicative of the fact that in love the object of love is seen in its singular being, and its qualities appear as expressions of that singularity. Love in that sense is transformative of the relation with the love-object, and this transformation becomes manifest in the commitment of the lover to sacrifice, following the call of the beloved. This sacrifice is a ‘sacrifice for nothing’ (Patočka), reflecting the unconditionality of the love-object through a suspension of all instrumentality and exchange relations. This article concludes with a short reading of the ‘good Samaritan’ parable as giving exemplary expression to the unconditionality of love. Full article

Neuroinflammation is a key factor in the progression of neurodegenerative diseases, driven by the dysregulation of molecular pathways and activation of the brain’s immune system, resulting in the release of pro-inflammatory and oxidative molecules. This chronic inflammation is exacerbated by peripheral leukocyte infiltration into the central nervous system. Medicinal plants, with their historical use in traditional medicine, have emerged as promising candidates to mitigate neuroinflammation and offer a sustainable alternative for addressing neurodegenerative conditions in a green healthcare framework. This review evaluates the effects of medicinal plants on neuroinflammation, emphasizing their mechanisms of action, effective dosages, and clinical implications, based on a systematic search of databases such as PubMed, SCOPUS, and Web of Science. The key findings highlight that plants like Cleistocalyx nervosum var. paniala, Curcuma longa, Cannabis sativa, and Dioscorea nipponica reduce pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β), inhibit enzymes (COX-2 and iNOS), and activate antioxidant pathways, particularly Nrf2. NF-κB emerged as the primary pro-inflammatory pathway inhibited across studies. While the anti-inflammatory potential of these plants is significant, the variability in dosages and phytochemical compositions limits clinical translation. Here, we highlight that medicinal plants are effective modulators of neuroinflammation, underscoring their therapeutic potential. Future research should focus on animal models, standardized protocols, and safety assessments, integrating advanced methodologies, such as genetic studies and nanotechnology, to enhance their applicability in neurodegenerative disease management. Full article

Bracken fern (Pteridium aquilinum (L.) Kuhn) is ubiquitous and acts as a cosmopolitan weed in pastures and similar environments. Despite its historical uses, it presents risks due to toxicity. This study, conducted in the second half of 2023, aimed to assess the environmental and health hazards of P. aquilinum, primarily focusing on its carcinogenic compound, ptaquiloside. The literature was comprehensively reviewed using diverse databases, including PubMed, Web of Science, Scopus, and Google Scholar. Information was synthesized from original research articles, meta-analyses, systematic reviews, and relevant animal studies. Animals grazing on bracken fern face annual production losses due to toxin exposure. The substantial impact on biodiversity, animal health, and human well-being arises from the presence of ptaquiloside and related compounds in milk, meat, and water, along with the increasing global prevalence of P. aquilinum and its swift colonization in acidic soil and fire-damaged areas. The objectives were to identify major bioactive compounds and explore their effects at molecular, cellular, pathological, and population levels. Various cooking techniques were considered to mitigate toxin exposure, although complete elimination remains unattainable. Therefore, the findings emphasize the need for cautious consumption. In conclusion, continued research is necessary to better understand and manage its environmental and health implications. Full article

The ancient concept of the underground is mainly associated with the outdated triadic cosmology. In modernity, some authors such as Dostoevsky and Nietzsche have dialectically referred to the underground as an alternative to the principle of reason or ground. Others—such as Hegel or Heidegger—have more radically linked this dialectic to the abyssal unground, recalling Boehme and Hölderlin. However, all these modern dialectical constellations of ground, underground, or unground have failed to provide a philosophical vision that would overcome the aporetic relationship between metaphysical grounding and phenomenal appearance. They have left aside the reality of the Marian underground, overshadowed by the Spirit and Cross and marked by Christ’s descent into the underground, by which the powers of the ancient underground were apocalyptically drawn into the liturgical celebration of a persecuted Church. In this article, I will link Jan Patočka’s phenomenology of the underground experience and Zdeněk Neubauer’s Marian metaphysics to prove that, in the apocalyptic horizon of suffering and persecution, the Sophianic and Marian revelations spell out the created form of Trinitarian being, that becomes a miraculous rescue of all relations and phenomena as the ground shining from within the underground, and the underground within the ground. Full article

Forests make up 34.1% of the Czech Republic total area and forest roads account for nearly the same length (47,465 km) as all other roads administered by the state and its regions (55,738 km). Forest roads are not as intensively used as other roads. On the other hand, as logging trucks carry the maximum permitted load on roads and forests create a specific microclimate, forest roads are subject to rapid wear. A road wearing course is generally designed for 20 years of service and for a maximum damage level of 25% before they are supposed to be reconstructed. To ensure this life cycle is adhered to, more efficient, faster, and more flexible surface damage detection adaptable for forest environment is needed. As smartphones and their optical devices, i.e., new iPhones with LiDAR sensors, become more advanced, the option arises to perform laser scanning on road surfaces using smartphones applications. This work aimed to test this technology and its precision applicability to assessing damage to a forest wearing course and compare it with another hand-held personal laser scanner (PLS_hh), represented in this study by GeoSLAM ZEB Horizon scanner, and more precise terrestrial laser scanning (TLS) technology, represented in this study by Faro Focus 3D laser scanner, which have started to replace tacheometric wearing course damage surveying thanks to their greater precision. So, this study involved a comparison of three alternative laser scanning methods focused especially on these, which are implemented in new iPhones for tacheometric surveying. First, a Faro Focus 3D laser scanner was used for the TLS method. Second, the PLS_hh method was tested on a GeoSLAM ZEB Horizon scanner. Third, another PLS_hh method using an iPhone 13 Pro with applications 3D Scanner and Polycam was evaluated. If we are comparing positional height accuracy of PLS_hh to tacheometric surveying on reference cross position height coordinates, ZEB Horizon achieved devXY and devZ RMSE 0.108 m; 0.025 m; iPhone 13 Pro with 3D Scanner app devXY and devZ RMSE 0.185 m; 0.021 m, and with Polycam app devXY and devZ RMSE 0.31 m; 0.045. TLS achieved the best results with devXY RMSE 0.049 and devZ RMSE 0.0077. The results confirm that only the TLS scanner achieves precision values in height differences applicable for an assessment of forest road wearing course damage measurement comparable with tacheometric surveying. Surprisingly, comparing the PLS_hh scanners to the TLS technology, they achieved interesting results, comparing their transverse profiles and 3D objects as digital surface models (DSM) of the road to TLS in height position. In transverse profiles, ZEB Horizon achieved devZ RMSE 0.032 m; iPhone 13 Pro with 3D Scanner app devZ RMSE 0.017 m, and with Polycam app devZ RMSE 0.041 m compared to the TLS method measured using a Faro Focus 3D static laser scanner. Comparing forest road DSM to Faro Focus 3D, ZEB Horizon achieved devZ RMSE 0.028 m; iPhone 13 Pro with 3D Scanner app devZ RMSE 0.018 m and with Polycam devZ RMSE 0.041 m. These results in height differences show that the height accuracy of PLS_hh achieves precision, which is applicable to determining the current shape of forest road wearing course compared to the required roof shape gradient. However, further testing provided the insight that such a kind of PLS_hh measurement is still only possible to use for the identification of a transverse profile shape, as in length measurement the length error increases. All PLS_hh are able to capture the current shape of forest road cross profile, but still they cannot be used for any design or calculation of material measurement needed for wearing course repair. Full article

Muscle and liver tissues from Italian heavy pigs were analyzed to investigate whether the chronic consumption of these products by local consumers could represent a health risk in relation to the contamination by some toxic metals and metalloids (TMMs). The concentrations of Al, As, Cd, Cr, Cu, Fe, Ni, Pb, Sn, U, and Zn were measured with an inductively coupled plasma–mass spectrometer, while Hg analysis was performed by using a mercury analyzer. Fe, Zn, and Cu were the most abundant elements in both tissues, while U was detected only at ultra-trace levels. As, Cd, Cu, Fe, Hg, Pb, U, and Zn showed significantly higher concentrations in livers compared to muscles (p ≤ 0.01), with Cd and Cu being 60- and 9-fold more concentrated in the hepatic tissue. Despite this, concentrations of all TMMs were found to be very low in all the samples to the point that the resulting estimated dietary intakes did not suggest any food safety concern. Indeed, intakes were all below the toxicological health-based guidance values or resulted in low margins of exposure. Nevertheless, in the calculation of the worst-case exposure scenario, the children’s estimated intake of Cd, Fe, and Zn through the sole consumption of pig liver contributed to more than 23, 38, and 39% of the tolerable weekly intakes of these elements, while the combined consumption of pig liver and pig muscle to more than 24, 46, and 76%. These findings alert about the probability of exceeding the toxicological guidance values of Cd, Fe, and Zn though the whole diet, suggesting long-term negative health effects for the younger population. Full article

The intensive and systematic scholarly interest in the relation of Patočka’s phenomenology to religion and Christianity is recent and has only intensified over the last ten years. Thus far, the topic has mainly been studied from philosophical and theological perspectives, and the extensive body of Patočka’s cultural writings has largely failed to attract the attention of scholars. Moreover, a culturological approach is virtually absent. Therefore, this article suggests focusing on the analysis of cultural archetypes in Patočka’s cultural writings related to the topic of religion and Christianity from this perspective. The cultural archetypes of the Faustian figures of Patočka’s cultural writings, whether Goethe’s Faust, Goethe’s Marguerite, or Mann’s Adrian Leverkühn, are all Socratic-Christic avatars that personify Patočka’s philosophical concept of “care for the soul” in the modern age. The legacy of Plato’s Greek philosophy and that of Western Christianity as presented by Patočka insist on the universally shared existential experience of finitude that should be grasped as a positive challenge in the strife for meaning. Patočka’s “titanism” and the archetypal titanic figures of his cultural writings are Patočkian manifestations of this universal effort. A culturological approach to Patočka’s thinking on religion and Christianity might thus prove most relevant. Full article

The article is on the effects of woody vegetation growing on the roadside on the temperature of the surface of cycle paths. The main hypothesis of the study is that vegetation has the effect of lowering the temperature of the surroundings in its shadow and thus improves the comfort of users of cycle paths in the summer months. The second hypothesis is to find out which type of road surface is most suitable for the thermal well-being of users. This goal was achieved by measuring the temperature of selected locations on cycle paths with different types of construction surfaces with nearby woody vegetation using a contactless thermometer over several days at regular intervals. The positions of the selected locations were measured using GNSS and the whole locality of interest was photographed using an unmanned aerial vehicle (UAV), or drone, and subsequently a digital surface model (DSM) of the area was created using a Structure from Motion (SfM) algorithm. This model served for the calculation of incident solar radiation during the selected days using the Solar Area Graphics tool with ArcGIS software. Subsequently, the effect of the shade of the surrounding vegetation on the temperature during the day was analysed and statistically evaluated. The results are presented in many graphs and their interpretation used to evaluate the effects of nearby woody vegetation and the type of road surface on the surrounding air temperature and the comfort of users of these routes. The results demonstrate the benefits of using UAVs for the purpose of modelling the course of solar radiation during the day, showing the effect of roadside vegetation on reducing the surface temperature of the earth’s surface and thus confirming the need for planting and maintaining such vegetation. Full article

Over the last decades, climate change has triggered an increase in the frequency of spruce bark beetle (Ips typographus L.) in Central Europe. More than 50% of forests in the Czech Republic are seriously threatened by this pest, leading to high ecological and economic losses. The exponential increase of bark beetle infestation hinders the implementation of costly field campaigns to prevent and mitigate its effects. Remote sensing may help to overcome such limitations as it provides frequent and spatially continuous data on vegetation condition. Using Sentinel-2 images as main input, two models have been developed to test the ability of this data source to map bark beetle damage and severity. All models were based on a change detection approach, and required the generation of previous forest mask and dominant species maps. The first damage mapping model was developed for 2019 and 2020, and it was based on bi-temporal regressions in spruce areas to estimate forest vitality and bark beetle damage. A second model was developed for 2020 considering all forest area, but excluding clear-cuts and completely dead areas, in order to map only changes in stands dominated by alive trees. The three products were validated with in situ data. All the maps showed high accuracies (acc > 0.80). Accuracy was higher than 0.95 and F1-score was higher than 0.88 for areas with high severity, with omission errors under 0.09 in all cases. This confirmed the ability of all the models to detect bark beetle attack at the last phases. Areas with no damage or low severity showed more complex results. The no damage category yielded greater commission errors and relative bias (CEs = 0.30–0.42, relB = 0.42–0.51). The similar results obtained for 2020 leaving out clear-cuts and dead trees proved that the proposed methods could be used to help forest managers fight bark beetle pests. These biotic damage products based on Sentinel-2 can be set up for any location to derive regular forest vitality maps and inform of early damage. Full article

This research was focused on the study of visual exposure evolution in the locality of the Drátenická skála nature monument (in the Czech Republic) and the surrounding forest complex in terms of history and through modelling for further possible stand development. The local forests underwent conversion from a natural fir-beech composition to an intensive spruce monoculture with few insect pests or windbreak events to an actual bark beetle infestation. Historic maps, landscape paintings, photographs, and orthophotos served as the basic materials for the illustration of the past situation. Further development was modelled using canopy height models and spectral properties captured by unmanned aerial vehicles (UAVs). As an example, the possible situation of total mortality among coniferous spruce trees after a bark beetle outbreak was modelled. Other options and a practical use of such preprocessed data are, for example, a model for opening and transforming the stands around the rock as one of the ongoing outcrop management trends in the protected landscape area (PLA) of Žďárské vrchy. Full article

This paper reviews the use of modern 3D image-based and Light Detection and Ranging (LiDAR) methods of surface reconstruction techniques for high fidelity surveys of small rock outcrops to highlight their potential within structural geology and landscape protection. LiDAR and Structure from Motion (SfM) software provide useful opportunities for rock outcrops mapping and 3D model creation. The accuracy of these surface reconstructions is crucial for quantitative structural analysis. However, these technologies require either a costly data acquisition device (Terrestrial LiDAR) or specialized image processing software (SfM). Recent developments in augmented reality and smartphone technologies, such as increased processing capacity and higher resolution of cameras, may offer a simple and inexpensive alternative for 3D surface reconstruction. Therefore, the aim of the paper is to show the possibilities of using smartphone applications for model creation and to determine their accuracy for rock outcrop mapping. Full article

Populations of Dracaena serrulata are disappearing at an alarming rate in the Arabian Peninsula. They are being destroyed by herders who use the leaves as fodder for camels, goats, and sheep during the dry season. Up until now, precise information about the current distribution and population status of D. serrulata in Oman have not been published. To fill this gap, the main aim of this work was to map the species distribution in the Dhofar Mountains (Oman) and to define the conservation and health status of the populations. Three isolated sub-populations of the study species were defined and mapped: the Jabal Samhan, Jabal al Qara, and Jabal al Qamar sub-populations. Dracaena serrulata occupies an area of 227 km² in the Dhofar Mountains. More than 43,000 trees were counted, and 2387 trees were inventoried in total. The Jabal Samhan sub-population is an example of an extensively damaged population with 59% of the trees recorded as dead and only 21% healthy trees. Populationsin the western portions of the Dhofar Mountains., Jabal al Qamar, and Jabal al Qara are comparatively abundant stands of healthy trees with a higher proportion of seedlings. The health of trees is strongly influenced by accessibility and precipitation provided by the southwest summer monsoon: the healthy individuals predominate on the steep terrain along the seaward facing cliffs. Full article

Detailed, three-dimensional modeling of trees is a new approach in botanical taxonomy. Representations of individual trees are a prerequisite for accurate assessments of tree growth and morphological metronomy. This study tests the abilities of 3D modeling of trees to determine the various metrics of growth habit and compare morphological differences. The study included four species of the genus Dracaena: D. draco, D. cinnabari, D. ombet, and D. serrulata. Forty-nine 3D tree point clouds were created, and their morphological metrics were derived and compared. Our results indicate the possible application of 3D tree point clouds to dendrological taxonomy. Basic metrics of growth habit and coefficients derived from the 3D point clouds developed in the present study enable the statistical evaluation of differences among dragon tree species. Full article

Unsustainable overgrazing is one of the most important threats to the endemic and endangered population of dragon’s blood tree (Dracaena cinnabari) on Socotra Island (Republic of Yemen). However, there is a lack of information about the exact population size and its conservation status. We estimated the population size of D. cinnabari using remote sensing data. The age structure was inferred using a relationship between crown projection area and the number of branch sections. The conservation importance of each sub-population was assessed using a specially developed index. Finally, the future population development (extinction time) was predicted using population matrices. The total population size estimated consists of 80,134 individuals with sub-populations varying from 14 to 32,196 individuals, with an extinction time ranging from 31 to 564 years. Community forestry controlled by a local certification system is suggested as a sustainable land management approach providing traditional and new benefits and enabling the reforestation of endemic tree species on Socotra Island. Full article

Antimicrobial peptides (AMPs) are crucial effectors of the innate immune system. They provide the first line of defense against a variety of pathogens. AMPs display synergistic effects with conventional antibiotics, and thus present the potential for combined therapies. Insects are extremely resistant to bacterial infections. Insect AMPs are cationic and comprise less than 100 amino acids. These insect peptides exhibit an antimicrobial effect by disrupting the microbial membrane and do not easily allow microbes to develop drug resistance. Currently, membrane mechanisms underlying the antimicrobial effects of AMPs are proposed by different modes: the barrel-stave mode, toroidal-pore, carpet, and disordered toroidal-pore are the typical modes. Positive charge quantity, hydrophobic property and the secondary structure of the peptide are important for the antibacterial activity of AMPs. At present, several structural families of AMPs from insects are known (defensins, cecropins, drosocins, attacins, diptericins, ponericins, metchnikowins, and melittin), but new AMPs are frequently discovered. We reviewed the biological effects of the major insect AMPs. This review will provide further information that facilitates the study of insect AMPs and shed some light on novel microbicides. Full article