Search Results (143)

The increase in data center facilities has led to higher energy consumption and a larger carbon footprint, prompting improvements in thermal environments for energy efficiency and server lifespan. Existing literature studies often overlook categorizing equipment for power usage effectiveness (PUE), addressing power efficiency measurement limitations and employee thermal comfort. These issues are addressed through an investigation of the PUE metric, a comparative analysis of various data center types and their respective cooling conditions, an evaluation of PUE in relation to established thermal standards and an assessment of employee thermal comfort based on defined criteria. Thirty-nine papers and ten websites were reviewed. The results indicated an average information technology (IT) power usage of 44.8% and a PUE of 2.23, which reflects average efficiency, while passive cooling was found to be more applicable to larger-scale data centers, such as Hyperscale or Colocation facilities. Additionally, indoor air temperatures averaged 16.5 °C with 19% relative humidity, remaining within the allowable range defined by ASHRAE standards, although employee thermal comfort remains an underexplored area in existing data center research. These findings highlight the necessity for clearer standards on power metrics, comprehensive thermal guidelines and the exploration of alternative methods for power metrics and cooling solutions. Full article

(1) Background: Our study investigates the green synthesis of Ag₂O/Ag nanoparticles using the isoflavone Puerarin as a bioreductor. (2) Methods: The PUE@Ag₂O/Ag nanoparticles were characterized using various techniques, including X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), electronic microscopy (TEM, SEM), energy dispersive X-ray spectroscopy (EDX), and dynamic light scattering (DLS). Biological activities were assessed through antimicrobial testing, cytotoxicity assays on human keratinocytes and melanoma cells, and an in ovo screening using the HET-CAM assay. (3) Results: The formation of crystalline Ag₂O/Ag nanoparticles with sizes below 100 nm was accomplished with Puerarin. Despite their high cytotoxicity at all tested concentrations, the nanoparticles showed antioxidant activity with IC₅₀ 981.5 ± 94.2 μg/mL, antibacterial activity against several clinically relevant nosocomial strains (Streptococcus pyogenes, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa), and no local irritant effects or inhibition of angiogenesis in the HET-CAM assay. (4) Conclusions: This study provides insights into the synthesis, characterization, and biological profile of PUE@Ag₂O/Ag nanoparticles for potential biomedical applications. Full article

In this study several phosphorus fertilizers were evaluated under controlled production conditions using Lactuca sativa var. baby leaf and a clay-loam soil of pH 6.5 as a plant–soil model system. Various inorganic (phosphate rock, monoammonium phosphate, struvite), organic (bone meal and bone meal pelletized with compost) and organomineral fertilizers (phosphate rock, monoammonium phosphate, struvite pelletized with compost) were compared. The soil properties, crop yield, morphological aspects and metabolomics of the plants were analyzed. After 45 days of the growing cycle, the organomineral fertilizers (OMFs) composed of compost and monoammonium phosphate (OMF₂(MAP+C)) or struvite (OMF₃(STR+C)) exhibited the best yield results: 101.37 g and 83.21 g, respectively. These treatments also exhibited the best phosphorus use efficiency (PUE) results: 7.40% and 8.33%, respectively. The yield of plants treated with MAP was 56.01 g, and its PUE was 5.33%. The yield of plants treated with STR was 62.10 g and the PUE was 4.67%. Accordingly, the development of OMFs with compost had a positive effect regarding MAP and STR fertilization. Lettuce fertilized with organic bone meal fertilizers had the lowest yield and nutrient use efficiency. The non-targeted metabolic study of green tissue revealed an overactivation of the TriCarboxylic Acids-TCA cycle and amino acid biosynthesis in plants fertilized with bone meal and phosphate rock treatments, likely as a plant stress response. The overall conclusion of this work is that the development of OMFs with compost is a good strategy to increase soil P availability and, accordingly, plant P uptake and %PUE. Full article

Data centers contribute to roughly 1% of global energy consumption and 0.3% of worldwide carbon dioxide emissions. The cooling system alone constitutes a substantial 50% of total energy consumption for data centers. Lowering Power Usage Effectiveness (PUE) of data center cooling systems from 2.2 to 1.4, or even below, is one of the critical issues in this thermal management area. In this work, a digital twin system of an Intelligent Data Center (IDC) prototype is designed to be capable of real-time monitoring the temperature distribution. Moreover, aiming to lower PUE, Deep Q-Learning Network (DQN) is further established to make optimization decisions of thermal management during cooling down of the local hotspot. The entire process of thermal management for IDC can be real-time visualized in Unity, forming the virtual entity of data center prototype, which provides an intelligent solution for sustainable data center operation. Full article

Despite the essential role of phosphorus (P) in rice growth, P-use efficiency (PUE) remains low due to limited bioavailable P in soils and an over-reliance on chemical fertilizers, leading to resource waste and environmental risks, such as eutrophication. This study investigates whether and how alternating wetting and moderate drying (AWMD) irrigation promotes P absorption and transport in rice. This study was conducted over two years using a pot experiment. Conventional flooding (CF) irrigation was applied throughout the growing season, while AWMD irrigation was imposed from two weeks after transplanting to one week before harvest. AWMD improved shoot biomass by 8.7–9.4% and the photosynthetic rate by 12–15%, significantly enhanced PUE, and optimized root traits and enzyme activities related to P uptake. It also promoted leaf acid phosphatase and ribonuclease activities, facilitating P remobilization to grains. In conclusion, AWMD enhanced the ability of roots to absorb P and optimized the redistribution of P between vegetative organs and grains, synergistically increasing grain yield and PUE in rice. Full article

Virtual machine (VM) placement in cloud datacenters is a complex multi-objective challenge involving trade-offs among energy efficiency, carbon emissions, and network performance. This paper proposes NCRA-DP-ACO (Network-, Cost-, and Renewable-Aware Ant Colony Optimization with Dynamic Power Usage Effectiveness (PUE)), a bio-inspired metaheuristic that optimizes VM placement across geographically distributed datacenters. The approach integrates real-time solar energy availability, dynamic PUE modeling, and multi-criteria decision-making to enable environmentally and cost-efficient resource allocation. The experimental results show that NCRA-DP-ACO reduces power consumption by 13.7%, carbon emissions by 6.9%, and live VM migrations by 48.2% compared to state-of-the-art methods while maintaining Service Level Agreement (SLA) compliance. These results indicate the algorithm’s potential to support more environmentally and cost-efficient cloud management across dynamic infrastructure scenarios. Full article

Cadmium (Cd) contamination in agricultural soils is increasing due to anthropogenic activities, posing a significant threat to plant growth and productivity. Phosphorus (P) has been suggested as a potential mitigator of Cd toxicity, yet the role of cotton genotypes with contrasting low-P tolerance in contaminated soils remains largely unexplored. A hydroponic experiment was conducted to assess the effects of Cd stress (5 μM) on Jimian169 (strong-low-P tolerant) and DES926 (weak-low-P tolerant) cotton genotypes under low-P (0.01 mM KH₂PO₄) and normal P (1 mM KH₂PO₄) conditions. The results revealed that Cd stress, especially under low-P, significantly reduced plant growth, dry matter, photosynthetic rate, and P use efficiency (PUE), while increasing oxidative damage through increased malonaldehyde levels and reactive oxygen species accumulation. These adverse impacts were very much evident in DES926 compared to Jimian169. In contrast, Jimian169 demonstrated greater resilience to Cd stress by mitigating oxidative damage through enhanced antioxidant enzyme activity, improved photosynthetic performance, and increased accumulation of osmoprotectants. These findings indicate that Jimian169 can better withstand Cd toxicity by enhancing photosynthesis, antioxidant defense mechanisms, and osmotic adjustment. This makes them a promising candidate for cultivation in Cd-contaminated, P-deficient soils. Full article

Efficient cooling and heat recovery systems are becoming increasingly critical in large-scale commercial and industrial facilities, especially with the rising demand for sustainable energy solutions. Traditional air-conditioning and refrigeration systems often dissipate significant amounts of waste heat, which remains underutilized. This study addresses the challenge of harnessing low-potential waste heat from such systems to support fifth-generation district heating and cooling (5GDHC) networks, particularly in moderate-temperate regions like Flanders, Belgium. To evaluate the technical and economic feasibility of waste heat recovery, a methodology is developed that integrates established performance metrics—such as the energy efficiency ratio (EER), power usage effectiveness (PUE), and specific cooling demand (kW/t)—with capital (CapEx) and operational expenditure (OpEx) assessments. Empirical correlations, including regression analysis based on manufacturer data and operational case studies, are used to estimate equipment sizing and system performance across three operational modes. The study includes detailed modeling of data centers, cold storage facilities, and large supermarkets, taking into account climatic conditions, load factors, and thermal capacities. Results indicate that average cooling loads typically reach 58% of peak demand, with seasonal coefficient of performance (SCOP) values ranging from 6.1 to a maximum of 10.3. Waste heat recovery potential varies significantly across building types, with conversion rates from 33% to 68%, averaging at 59%. In data centers using water-to-water heat pumps, energy production reaches 10.1 GWh/year in heat pump mode and 8.6 GWh/year in heat exchanger mode. Despite variations in system complexity and building characteristics, OpEx and CapEx values converge closely (within 2.5%), demonstrating a well-balanced configuration. Simulations also confirm that large buildings operating above a 55% capacity factor provide the most favorable conditions for integrating waste heat into 5GDHC systems. In conclusion, the proposed approach enables the scalable and efficient integration of low-grade waste heat into district energy networks. While climatic and technical constraints exist, especially concerning temperature thresholds and equipment design, the results show strong potential for energy savings up to 40% in well-optimized systems. This highlights the viability of retrofitting large-scale cooling systems for dual-purpose operation, offering both environmental and economic benefits. Full article

This study evaluated the phosphorus use efficiency (PUE) in two genotypes and one cultivar of Brachiaria decumbens (HD1, HD4, and Basilisk) and the productive, morphogenic, and structural responses. The experimental design used was randomized blocks with five P rates (0, 13, 26, 52, and 104 mg dm⁻³). There was no forage × P rate interaction (p > 0.05), but the P rates affected the leaf appearance rate (TAR; p = 0.0314), leaf life span (LLS; p = 0.0207), phyllochron (PC; p = 0.0207), leaf elongation rate (LER; p = 0.0350), stem elongation rate (SER; p = 0.0109), and the number of live leaves (NLL; p = 0.0033). The LAR, LLS, and PC followed quadratic trends, increasing up to 52 mg dm⁻³, while the PC declined. The FLL, SER, and NLL increased linearly. HD1 had the highest final leaf length, LER, and NLL, while Basilisk had the lowest. There was an interaction for tiller population density (p = 0.0431), with increases of 0.26, 0.28, and 0.24 tillers for HD4, HD1, and Basilisk, respectively. Forage production (FP) increased with P, gaining 0.51 g of DM for each mg dm⁻³ of P added. The HD1 genotype showed higher FLL, LER, NLL, FP, and higher PUE than the HD4 genotype and the Basilisk cultivar. HD1 was more responsive to higher P rates for root production, indicating a greater need for nutrients to reach its productive potential. Phosphate fertilization positively influenced morphogenesis and forage production in the evaluated genotypes and cultivars. The HD1 genotype stood out in relation to the others, showed superiority in forage and root production, and demonstrated greater efficiency in the use of P, at a dose of 13 mg dm⁻³. Full article

The increasing global food demand, the degradation of one-third of agricultural land, and climate change pose significant threats to food production. Maize and soybean intercropping can enhance yields and land use efficiency, yet the year-interval effects of continuous intercropping on yield, yield sustainability, and phosphorus use efficiency (PUE) remain unclear. This study evaluates the effects of continuous maize/soybean intercropping over year intervals on yield, PUE, and sustainability. A seven-year field trial (2017–2023) was conducted on acidic soil, comparing two cropping systems: maize monocropping and maize intercropped with soybean. The results showed that continuous maize/soybean intercropping outperformed maize monocropping across all year intervals. Over the first, third, and seventh year intervals, maize yield increased by 37%, 35%, and 58%, respectively, with a 55% average increase over the seven years. Intercropping also enhanced P use efficiency, as evidenced by AE, RE, PFP, and CPF increases. In the first year, AE, PFP, RE, and CPF increased by 48%, 37%, 27%, and 16%, respectively; after the third year interval, these metrics improved by 40%, 35%, 26%, and 14%; and after the seventh year interval, they rose by 60%, 58%, 24%, and 10.5%. The average AE, RE, and PFP increases over seven years were 53%, 52%, and 27%, respectively, while CPF increased by 13%. The SEM analysis further confirmed the substantial impact of the seventh year intercropping interval on maize yield, sustainability, and PUE. This study demonstrates that continuous maize/soybean intercropping can enhance maize yield, PUE, and sustainability, with the seventh year interval offering the most pronounced benefits. These findings provide valuable insights for improving food security and nutrient management challenges. Full article

Background and Objectives: Diabetic hepatopathy, characterized by hepatic hypoxia and metabolic dysregulation, has a rising global incidence and prevalence, with limited effective treatments. Hepatic hypoxia activates hypoxia-inducible factor-1 alpha (HIF-1α), regulating sphingolipid metabolism and elevating ceramide, a key factor in insulin resistance. Puerarin (Pue), a flavonoid derived from Pueraria lobata, exhibits therapeutic effects in diabetes, but its effects on hypoxia-related hepatic metabolism are unclear. This study investigates Pue’s mechanisms in modulating hepatic metabolism, focusing on HIF-1α and sphingolipid metabolism. Methods: Using bioinformatics and molecular docking, HIF-1α was identified as a key target in diabetic liver disease, confirmed via drug affinity responsive target stability. In vitro experiments utilized insulin-resistant HepG2 cells to assess glucose intake and HIF-1α expression. In vivo, type 2 diabetes mellitus (T2DM) was induced in mice using a high-fat diet and streptozotocin injections. Pue administration was evaluated for its effects on fasting blood glucose, oral glucose tolerance, and hepatoprotective effects. Liver metabolomics and qPCR/Western blot analyses were conducted to assess metabolic pathways. Results: Pue increased glucose uptake in HepG2 cells and bound HIF-1α. Pue reduced HIF-1α expression in HepG2 cells, an effect attenuated by the HIF-1α stabilizer DMOG. Pue improved fasting blood glucose, oral glucose tolerance, and hepatoprotective effects in T2DM mice, which DMOG reversed. Metabolomics revealed that Pue modulates sphingolipid metabolism, decreasing ceramide content. qPCR and Western blot results confirmed that Pue dramatically decreases HIF-1α and SPTLC2 expression. Conclusions: Pue improves diabetic hepatopathy by reducing ceramide expression through the HIF-1α/SPTLC2 pathway, offering a novel therapeutic strategy for diabetes management. Full article

While soil responses to organic and inorganic phosphorus (P) fertilizers have been widely studied, plant physiological and molecular responses remain insufficiently characterized. Such an understanding is necessary to develop sustainable P fertilization strategies that enhance plant performance in soils with P limitations. This study investigated the impact of poultry manure (PM) and its combination with phytase enzyme on molecular plant responses involved in P use efficiency (PUE) of ryegrass plants growing on a P-deficient Andisol. A greenhouse experiment under controlled conditions was performed to evaluate soil properties, plant biomass, P uptake, plant performance, and the expression of P transporters under the following P treatments: P deficiency (PD), mineral fertilizers (F), PM alone, and PM combined with phytase. The combination of PM and phytase enhanced soil P availability by 60% and increased soil P enzyme activities 2.6-fold, facilitating the mineralization of organic P. This resulted in a 63% increase in shoot P concentration and a 35% enhancement in shoot biomass. Additionally, oxidative stress markers decreased, with lipid peroxidation in roots reduced up to five-fold, while antioxidant activity increased 1.6-fold. Molecular analysis revealed that the expression of the P transporter gene LpPHT1;4 was upregulated 9.3-fold, indicating an improved capacity for P acquisition and utilization. These findings suggest that phytase-mediated hydrolysis of organic P and the activation of plant P transporters are key mechanisms driving enhanced P uptake and efficiency in P-deficient soils. Full article

EV motors and machine elements operate at higher speeds, generate significant heat and noise (vibration), and subject lubricants (bearings) to multiple degrading factors, requiring thermal stability, wear protection, mitigating wear mechanisms like pitting and scuffing, and low electrical conductivity to prevent arcing damage to bearings. This study evaluates the tribological performance of four types of greases—PUEs, PUPao, PUEth (polyurea-based), and LiPAO (lithium–calcium complex-based)—to determine their suitability for electric motor bearings. Key performance metrics include tribological properties, electrical resistivity, leakage, bearing noise, and wear behavior. A four-ball wear test ranks the greases by scar diameter as PUPao < PUEs < PUEth < LiPAO, while the coefficient of friction is observed in the range of 0.15–0.18, with LiPAO exhibiting the lowest friction. Electrical resistivity tests reveal that PUEs grease has the lowest resistivity. Electrical leakage tests, conducted with a voltage differential across bearings, assess pitting damage, with PUEth and LiPAO showing evidence of surface pitting. Optical microscopy and scanning electron microscopy analysis is carried out to examine the pitting. In bearing noise tests, PUEs demonstrates the lowest noise levels, whereas LiPAO produces the highest. Visual and microscopic examination of the greases further characterizes their lubricating properties. Based on overall performance, the greases are ranked in suitability for electric motor applications as PUEs > PUPao > PUEth > LiPAO. The findings highlight the critical need for selecting appropriate grease formulations to ensure optimal bearing performance under varying operational conditions. Full article

Bisphenol S (BPS) is a widespread environmental endocrine disrupter that can cause hepatotoxicity, neurotoxicity and negative effects on reproduction. Puerarin (PUE) has been found to have anti-inflammatory, antioxidant, and neuroprotective properties, however, its potential protective effects against BPS-induced neurotoxicity and the underlying mechanisms are still not fully understood. In this study, HT22 cells were exposed to different concentrations of BPS with or without PUE. Cell viability, apoptosis, oxidative damage, and the expression level of axon-injury-related genes and the BDNF/TrkB/CREB pathway were analyzed. The results showed that 40 μM to 180 μM BPS and 100 μM to 180 μM PUE significantly decreased the cell viability of HT22 cells, but in the 80 μM PUE group, the cell viability was higher than control group, and the ratio of 1.1. Meanwhile, BPS increased the production of ROS and MDA but decreased the GSH and SOD. However, supplementation with PUE was alleviated the oxidative damage. PUE also alleviated the apoptosis rate that induced by BPS. Additionally, BPS decreased the expression levels of mRNA and proteins of synaptic-related genes, but inhibited the expression levels of mRNA and proteins of the BDNF/TrkB/CREB signaling pathway. Interestingly, PUE was found to significantly recover the expression of synaptic related genes, but also upregulated the expression of the BDNF/TrkB/CREB pathway. In conclusion, our study proved that PUE can attenuate the neurotoxicity effect of bisphenol S, which related to oxidative damage in HT22 cells by regulating the BDNF/TrkB/CREB signaling pathway. This study is not only the first to demonstrate that PUE can mitigate BPS-induced neurotoxicity through oxidative stress modulation, but also provides a novel therapeutic approach involving the BDNF/TrkB/CREB pathway. These findings offer promising insights into natural-based strategies for protecting against environmental neurotoxins and provide a foundation for future therapeutic developments targeting BPS-induced neurotoxicity. Full article

As Information Technology continues to rapidly evolve, the scale and energy consumption of data centers have seen a significant surge. Traditional air-cooling systems in data centers are notably energy intensive. This study proposes an innovative dual-cycle two-phase cooling system (DTCS) for retrofitting existing server cabinets. The system integrates the two synergistic subsystems of a pump-driven chip-level two-phase cooling system (PCTCS) and a pump-driven backplane-level two-phase cooling system (PBTCS). The PCTCS provides year-round natural cooling of high-power chips, and experimental results indicate that even under extreme outdoor conditions of up to 42 °C, the PCTCS can maintain the chip temperature at 76 °C. At the same time, the PBTCS effectively cools all components in the cabinet except the high-power chips. By efficiently controlling the chip temperature through the PCTCS, the novel DTCS ensures stable operation at data room temperatures up to 33 °C, thereby significantly reducing the energy consumption of the cooling system. The average annual pPUE of the cooling system is 1.078 at the test site in Xiangyang, Hubei province in China. The DTCS could perform well across various Chinese cities even under severe hot and moist conditions, with the average annual pPUE consistently below 1.1. Full article