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Article

14 Citations

5,446 Views

13 Pages

Lactoferrin Induces the Synthesis of Vitamin B6 and Protects HUVEC Functions by Activating PDXP and the PI3K/AKT/ERK1/2 Pathway

Huiying Li,
Yizhen Wang,
Huaigu Yang,
Li Liu,
Jiaqi Wang and
Nan Zheng

Int. J. Mol. Sci.2019, 20(3), 587;https://doi.org/10.3390/ijms20030587

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30 January 2019

As a nutritional active protein in foods, multiple studies of the biological activities of lactoferrin had been undertaken, including antioxidant, antiviral, anti-inflammatory, antitumor, antibiosis, and antiparasitic effects, while the mechanism rel...

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Article

6 Citations

3,349 Views

16 Pages

ELK1/MTOR/S6K1 Pathway Contributes to Acquired Resistance to Gefitinib in Non-Small Cell Lung Cancer

Lei Zhao,
Yifang Wang,
Xin Sun,
Xiujuan Zhang,
Nicole Simone and
Jun He

Int. J. Mol. Sci.2024, 25(4), 2382;https://doi.org/10.3390/ijms25042382

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17 February 2024

The development of acquired resistance to small molecule tyrosine kinase inhibitors (TKIs) targeting epidermal growth factor receptor (EGFR) signaling has hindered their efficacy in treating non-small cell lung cancer (NSCLC) patients. Our previous s...

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