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3,959 Views

11 Pages

Crystal Structure and Spectroscopic Analysis of the Compatible Solute Nγ-Acetyl-L-2,4-Diaminobutyric Acid

Lea Martin,
Wilhelm Klein,
Sebastian P. Schwaminger,
Thomas F. Fässler and
Sonja Berensmeier

Crystals2020, 10(12), 1136;https://doi.org/10.3390/cryst10121136

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12 December 2020

Compatible solutes are low molecular weight, highly water-soluble and neutrally net-charged molecules with various protective functionalities that accumulate and are produced in microorganisms. Their multi-purpose functionalities, also adaptable in v...

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16 Pages

Compatible Solutes Prevent Lung Inflammation and Reduction in CFTR Induced by Combustion-Derived Nanoparticles in Human and Rodent Experimental Systems

Tim Spannbrucker,
Klaus Unfried and
Tamara Hornstein

Int. J. Mol. Sci.2025, 26(19), 9487;https://doi.org/10.3390/ijms26199487

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28 September 2025

The compatible solute ectoine is known to attenuate inflammatory effects in the airways after exposure to combustion-derived nanoparticles. Pro-inflammatory signaling in epithelial cells, as well as antiapoptotic mechanisms in neutrophilic granulocyt...

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