3 Results Found

Advanced Search

Select all

Results per page

Select all

Article

10 Citations

4,570 Views

16 Pages

Pseudophosphatase MK-STYX Alters Histone Deacetylase 6 Cytoplasmic Localization, Decreases Its Phosphorylation, and Increases Detyrosination of Tubulin

Yuming Cao,
Dallas A. Banks,
Andrew M. Mattei,
Alexys T. Riddick,
Kirstin M. Reed,
Ashley M. Zhang,
Emily S. Pickering and
Shantá D. Hinton

Int. J. Mol. Sci.2019, 20(6), 1455;https://doi.org/10.3390/ijms20061455

-

22 March 2019

The catalytically inactive mitogen-activated protein (MAP) kinase phosphatase, MK-STYX (MAPK (mitogen-activated protein kinase) phosphoserine/threonine/tyrosine-binding protein) interacts with the stress granule nucleator G3BP-1 (Ras-GAP (GTPase-acti...

Full Article

Review

59 Citations

8,159 Views

14 Pages

Pseudophosphatases as Regulators of MAPK Signaling

Emma Marie Wilber Hepworth and
Shantá D. Hinton

Int. J. Mol. Sci.2021, 22(22), 12595;https://doi.org/10.3390/ijms222212595

-

22 November 2021

Mitogen-activated protein kinase (MAPK) signaling pathways are highly conserved regulators of eukaryotic cell function. These enzymes regulate many biological processes, including the cell cycle, apoptosis, differentiation, protein biosynthesis, and...

Full Article

Review

18 Citations

4,389 Views

21 Pages

The Roles of Pseudophosphatases in Disease

Andrew M. Mattei,
Jonathan D. Smailys,
Emma Marie Wilber Hepworth and
Shantá D. Hinton

Int. J. Mol. Sci.2021, 22(13), 6924;https://doi.org/10.3390/ijms22136924

-

28 June 2021

The pseudophosphatases, atypical members of the protein tyrosine phosphatase family, have emerged as bona fide signaling regulators within the past two decades. Their roles as regulators have led to a renaissance of the pseudophosphatase and pseudoen...

Full Article