Search Results (134)

This study aims to foster a guideline for sustainable supply chain management for edible insect production through a comprehensive review and critical analysis of the current situation, focusing especially on Thailand’s perspective. It addresses the traditional culture and modern practice of insect consumption and how these factors affect current production for commercial purposes. The advantages of nutritional values and farming with edible insects over traditional livestock farming are highlighted. A threats, opportunities, weaknesses, and strengths (TOWS) matrix analysis, producing action-oriented strategies, was based on an analysis of the strengths, weaknesses, opportunities, and threats (SWOT) of Thailand’s edible insect industry. The strategies include enhancement of production and product quality, innovation of intelligent production techniques and agriculture, fortification of branding and product development, encouragement of research and development investment, and the promotion of local product identity. The analysis emphasizes the value of sustainable supply chain management and advocates for the advancement of the bio-circular green (BCG) economy strategy for the edible insect industry. It also emphasizes the importance of stakeholder collaboration and implementing regulations to ensure food safety and sustainable production. Full article

Coffee cherry pulp (CCP), a coffee by-product rich in pectin and phenolic compounds, serves as a valuable substrate for microbial enzyme production, improving the nutritional and antioxidant properties of poultry feed. This study evaluated the potential of Kluyveromyces marxianus ST5 to produce pectin-degrading enzymes using CCP. Under unoptimized conditions, the pectin lyase (PL) and polygalacturonase (PG) activities were 3.29 ± 0.22 and 6.32 ± 0.13 U/mL, respectively. Optimization using a central composite design (CCD) identified optimal conditions at 16.81% (w/v) CCP, 5.87% (v/v) inoculum size, pH 5.24, and 30 °C for 48 h, resulting in PL and PG activities of 9.17 ± 0.20 and 15.78 ± 0.14 U/mL, representing increases of 178.7% and 149.7% over unoptimized conditions. Fermented CCP was further evaluated using an in vitro chicken gastrointestinal digestion model. Peptide release increased by 66.2% compared with unfermented CCP. Antioxidant capacity also improved, with significant increases observed in DPPH (32.4%), ABTS (45.0%), and FRAP (42.3%) assays, along with an 11.1% increase in total phenolic content. These results demonstrate that CCP bioconversion by K. marxianus ST5 enhances digestibility and antioxidant properties, supporting its potential as a sustainable poultry feed additive and contributing to the valorization of agro-industrial waste. Full article

Coffee silverskin (CS), a by-product generated during coffee roasting, contains high levels of xylan hemicellulose and protein, making it a promising substrate for functional ingredient production. This study developed an integrated bioprocess to simultaneously produce bioactive peptides and xylooligosaccharides (CS-XOS) from CS. Conventional alkaline extraction (CAE) under optimized conditions (1.0 M NaOH, 90 °C, 30 min) yielded 80.64 mg of protein per gram of CS and rendered the solid residue suitable for XOS production. Enzymatic hydrolysis of the extracted protein using protease_SE5 generated low-molecular-weight peptides (0.302 ± 0.01 mg/mL), including FLGY, FYDTYY, and FDYGKY. These peptides were non-toxic, exhibited in vitro antioxidant activity (0–50%), and showed ACE-inhibitory activities of 60%, 26%, and 79%, and DPP-IV-inhibitory activities of 19%, 18%, and 0%, respectively. Concurrently, the alkaline-treated CS solid residue (ACSS) was hydrolyzed using recombinant endo-xylanase, yielding 52.5 ± 0.08 mg of CS-XOS per gram of ACSS. The CS-XOS exhibited prebiotic effects by enhancing the growth of probiotic lactic acid bacteria (μ_max 0.100–0.122 h⁻¹), comparable to commercial XOS. This integrated bioprocess eliminates the need for separate processing lines, enhances resource efficiency, and provides a sustainable strategy for valorizing agro-industrial waste. The co-produced peptides and CS-XOS offer significant potential as functional food ingredients and nutraceuticals. Full article

Purpose: To assess the performance of 2D T2-weighted (w) Turbo Spin Echo (TSE) MRI reconstructed with a deep learning (DL)-powered super resolution reconstruction (SRR) algorithm combining compressed sensing (CS) denoising and resolution upscaling for high-resolution hippocampal imaging in patients with (epileptic) seizures and suspected hippocampal pathology. Methods: A 2D T2w TSE coronal hippocampal sequence with compressed sense (CS) factor 1 (scan time 270 s) and a CS-accelerated sequence with a CS factor of 3 (scan time 103 s) were acquired in 28 patients. Reconstructions using the SRR algorithm (CS 1-SSR-s and CS 3-SSR-s) were additionally obtained in real time. Two readers graded the images twice, based on several metrics (image quality; artifacts; visualization of anatomical details of the internal hippocampal architecture (HIA); visibility of dentate gyrus/pes hippocampi/fornix/mammillary bodies; delineation of gray and white matter). Results: Inter-readout agreement was almost perfect (Krippendorff’s alpha coefficient = 0.933). Compared to the CS 1 sequence, the CS 3 sequence significantly underperformed in all 11 metrics (p < 0.001-p = 0.04), while the CS 1-SRR-s sequence outperformed in terms of overall image quality and visualization of the left HIA and right pes hippocampi (p < 0.001-p < 0.04) but underperformed in terms of presence of artifacts (p < 0.01). Lastly, relative to the CS 1 sequence, the CS 3-SRR-s sequence was graded worse in terms of presence of artifacts (p < 0.003) but with improved visualization of the right pes hippocampi (p = 0.02). Conclusion: DL-powered SSR demonstrates its capacity to enhance imaging performance by introducing flexibility in T2w hippocampal imaging; it either improves image quality for non-accelerated imaging or preserves acceptable quality in accelerated imaging, with the additional benefit of a reduced scan time. Full article

Background: Antimicrobials are crucial for animal health and food security. However, their overuse in animals can lead to the emergence of resistant microorganisms. Antimicrobial resistance (AMR) poses a global public health threat that impacts both animal and human health. The objective of this study was to estimate the antimicrobial consumption (AMC) of veterinary antimicrobials at the national level using import data from January to December 2021, available from the Uganda National Drug Authority (NDA). Methods: The World Organization for Animal Health (WOAH) methodology was applied using the Anatomical Therapeutic Chemical classification codes for veterinary medicines. Results: Approximately 88,387.37 kg (88.39 tonnes) of veterinary antimicrobials were consumed in 2021. Parenteral veterinary antimicrobials accounted for 63.8% (56,375.65 kg) and oral veterinary antibacterials accounted for 36.2% (32,011.71 kg). Tetracyclines were the single most consumed veterinary antimicrobial class, accounting for 62.7% of total consumption. Oxytetracycline was the most consumed antibacterial (58.4%), followed by sulphadiazine + trimethoprim (11.1%), penicillin g/dihydrostreptomycin (7.4%), penicillin G procaine + dihydrostreptomycin (6.8%), and tetracycline (3.5%), respectively. Out of all imported veterinary antimicrobials, 76% belonged to the World Health Organization (WHO)’s Highly Important Antimicrobials (HIA) category, 16% to the Critically Important (CIA), and 9% to the Highest Priority Critically Important (HPCIA) categories. Imported colistin accounted for 0.1% of total veterinary consumption. Conclusions: This study contributes to understanding antimicrobial consumption in Uganda’s livestock sector and, for the NDA, leaves in place a system for routine surveillance at a national level. We recommend strict regulatory oversight on the importation and use of colistin and macrolides to address AMR. Full article

Figurative language is a complex construct related to intelligence. Psychology and psycholinguistics are trying to understand it from an interdisciplinary perspective, but studies are still scarce, methodologies are heterogeneous, and results are difficult to integrate. Some studies suggest that understanding the cognitive processes underlying figurative language and its forms could provide a new approach to understanding intellectual differences, such as high intellectual ability (HIA), and new instruments to assess it. The language of HIA children develops earlier and includes the use of irony, which involves metalinguistic skills. In this context, the present study aims to offer an instrument, called the verbal irony questionnaire (or VIrQ), to test the comprehension of verbal irony in students with HIA. A convenience sample of n = 169 students with HIA, aged between 7 and 15 years, responded to the VIrQ. An exploratory factor analysis was conducted. The results revealed that 33 items were retained and categorized into four factors. F1, ironic dissociation (14 items); F2, ironic attitude (8 items); F3, ironic constructions (7 items); and F4, reinforced irony echo (4 items). All factors have adequate reliability indices above 0.70 and below 0.95. Finally, new perspectives are also discussed. Full article

This study aimed to identify differences in match running performance (MRP) on artificial turf (AT) and natural grass (NG) among female football players. The players’ MRPs (AT; 96 observations, NG; 80 observations) were obtained from all matches (n = 22) of the First Slovenian women’s football league in the season 2023/24 using a global positioning system. Data were categorized into four subsets according to the players’ tactical roles: central defensive player (CD), wide defensive player (FB), midfield player (CM), and offensive player (OF). The variables included total distance (TD), high-intensity running (HIR), high-intensity accelerations (HIA), and decelerations (HID). Results indicated that (i) CDs (Cohen’s d (d) = 0.93) and CMs (d = 1.07) covered significantly greater TD on AT compared to NG, with (ii) no significant differences in TD among FBs and OFs. Additionally, (iii) similar HIR, HIA, and HID values were found for players on all playing positions, irrespective of the pitch surface. These findings suggest that overall match intensity remains consistent between surfaces, but that AT may impose a higher physical demand regarding match volume for CDs and CMs. Therefore, the physical condition of these players should be a major consideration when playing on AT. Full article

Despite various opportunities, urban development projects have been causing significant challenges to the preservation and conservation of historic cultural heritage. In particular, an increasing number of World Heritage (WH) properties are impacted by the direct and indirect effects of development projects, reflecting the existing uprising conflict. Grasping the challenge, Heritage Impact Assessment (HIA) has been developed as a proactive assessment tool to identify and predict potential impacts, mitigate the negative impacts on heritage values, and sustain the attributes conveying OUVs in WH assets. The growing demand for urban development and its potential impacts on cultural heritage properties underscores the necessity for the development of a targeted Heritage Impact Assessment methodology for urban development threats. To adequately address multiple impacts, this paper proposes a triangulation of a qualitative matrix for impact identification and a semi-quantitative indicator-based index for impact analysis and evaluation. The methodology is applied to the World Heritage property of Masjed-e Jame of Isfahan in Iran. In drawing upon this example, a systematic and integrated impact assessment procedure is developed to capture a broad category of potential impacts and their significance that is crucial for determining site-specific mitigation strategies and informed decision-making within the context of heritage management and sustainable urban development. Full article

This project report explores the use of a Health in All Policies (HiAP) approach by the Georgia Health Policy Center (GHPC) to integrate health perspectives into affordable housing policy and practice in Georgia. It focuses on five interconnected projects from over a decade-long collaboration to illustrate how the GHPC team started with a Health Impact Assessment (HIA) to seed cross-sector partnerships and then sustained them through subsequent collaborations. These projects included comprehensive-, intermediate-, and rapid-scale HIAs, as well as direct collaborations on housing development funding applications and a multidisciplinary research study on public housing renovations. This paper documents how HiAP tactics were applied across these projects to foster sustained collaboration and promote health equity. The insights offered highlight how the HiAP approach cultivated mindset shifts among public health practitioners, housing stakeholders, and policymakers, leading to a broader understanding of health and housing intersections. This synthesis contributes practical guidance for practitioners looking to advance the Vital Conditions for Health and Well-Being through housing policy initiatives. Full article

Background: Caffeine is a well-known psychostimulant reputed to alleviate the deleterious effects of sleep deprivation. Nevertheless, caffeine can alter sleep duration and quality, particularly during recovery sleep. We evaluated the effects of acute caffeine intake on the duration and quality of recovery sleep following total sleep deprivation (TSD), taking into account daily caffeine consumption. Methods: Forty-one participants performed a double-blind, crossover TSD protocol (38 h of continuous wakefulness) with acute caffeine or placebo. Caffeine (2.5 mg/kg) or placebo was administered twice during continuous wakefulness (last treatment 6.5 h before bedtime for the recovery night). Polysomnographic measurements were recorded using a connected headband. Results: TSD was associated with a rebound in total sleep time (TST) on the recovery night (+110.2 ± 23.2 min, p < 0.001). Caffeine intake decreased this recovery TST (−30.2 ± 8.2 min p = 0.02) and the N3 sleep stage duration (−35.6 ± 23.2 min, p < 0.01). Caffeine intake altered recovery sleep continuity (increased number of long awakenings), stability (higher stage transition frequency), and organization (less time spent in complete sleep cycle) and decreased the delta power spectral density during NREM sleep. On the recovery night, habitual daily caffeine consumption was negatively correlated with TST in caffeine and placebo conditions and positively correlated with wake after sleep onset (WASO) duration and with the frequency of long (>2 min) awakenings in the caffeine condition only. Conclusions: Acute caffeine intake during TSD affects nighttime recovery sleep, with an interaction with daily consumption. These results may influence advice on caffeine intake for night-shift workers. (NCT03859882). Full article

Health impact assessment (HIA) is a prospective approach that aims to identify the potential consequences of policies or projects on health in order to propose measures to make them healthier. Initiated in the late nineties, the approach emerged over ten years ago in France. However, the evaluation of HIA effectiveness remains seldomly practised and its theoretical background should be deepened. The aim of this article is to generate a discussion on how to evaluate HIA effectiveness and contribute to its methodological tooling, drawing on an evaluative experience of multiple French HIAs. Our work is based on an iterative approach between an analysis of the evaluation literature and a critical look at an HIA evaluation. We first carried out the evaluation of three HIAs in 2017–2018, combining a normative approach and qualitative research in order to explore each HIA as a phenomenon in its own context. Two years later, we conducted a self-assessing expertise on this evaluation, supported by an analysis of the literature in the field of public policy evaluation, in order to refine the theoretical framework for evaluating HIA effectiveness and ultimately to enhance professional practice by evaluators. This work led to the production of a logic model that identifies, through three dimensions (context, implementation and governance), the multiple pathways that HIA may take to bring about change. It also seeks to show the interdependence of these pathways towards change and helps identify the key drivers and mechanisms of HIA success. In this respect, it complements existing HIA evaluation models as it can serve both as a generic framework for evaluating HIA effectiveness and as an instrument for monitoring HIA implementation. Full article

Collagen hydrolysates derived from tuna tendons have potential applications in various industries, but sterilization is crucial to ensure their safety. This study investigated the effects of ethylene oxide (EtO), beta radiation, and gamma radiation sterilization methods on the structural and functional properties of collagen hydrolysates using nuclear magnetic resonance (NMR) spectroscopy, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), and differential scanning calorimetry (DSC). EtO sterilization caused significant physical and chemical changes in the hydrolysates, as evidenced by the altered appearance and ¹H-NMR and ¹³C-NMR spectra. In contrast, beta and gamma radiation did not induce notable changes in the physical characteristics and NMR spectra. MALDI-TOF MS analysis revealed slight alterations in the molecular weight distribution after sterilization, with beta irradiation causing a minor decrease and gamma irradiation and EtO leading to small increases. DSC analysis showed shifts in the heat absorption peaks after sterilization, indicating changes in the thermal properties. The findings suggest that while all three methods effectively sterilize collagen hydrolysates, EtO causes more significant structural modifications compared to beta and gamma radiation. This study provides valuable insights into the impact of sterilization on collagen hydrolysates, facilitating the selection of appropriate methods for specific applications. Full article

The occurrence and spread of infectious diseases pose considerable challenges to public health. While the relationship between the built environment and the spread of infectious diseases is well-documented, there is a dearth of urban planning tools specifically designed for conducting Health Impact Assessments (HIAs) targeted at infectious diseases. To bridge this gap, this paper develops a comprehensive framework of an HIA for Urban Planning and Epidemic (HIA4UPE), formulated by considering the progression of public health incidents and the distinct transmission patterns of infectious diseases. This framework is designed to provide a comprehensive assessment by including a health risk-overlay assessment, health resource-quality assessment, health resource-equality assessment, and health outcome-impact prediction, enabling a multidimensional evaluation of the potential impacts of current environmental conditions or planning proposals on the incidence of infectious diseases. Furthermore, this paper advances the application of spatial analysis and computation, comprehensive assessment methodologies, and predictive analytics to conduct specific assessments. The theoretical framework and analytical tools presented in this paper contribute to the academic discourse and offer practical utility in urban planning and policymaking on epidemic prevention and control. Full article

Multiple emulsions can dissolve some substances with different properties, such as hydrophilicity and lipophilicity, into different phases. They play an important role in protection, controlled release and targeted release of the encapsulated substances. However, it’s poor stability has always been one of the main problems restricting its application in the food industry. For this reason, a heat-induced aggregate (HIA) of Maillard graft product of isomalto-oligosaccharides (IMO), as well as egg white protein (EWP), was used as hydrophilic emulsifier to improve the stability of W₁/O/W₂ emulsions. Moreover, gelatin was added into the internal aqueous phase (W₁) to construct W₁/O/W₂ emulsion-gels system. The encapsulation efficiency of HIA-stabilized W₁/O/W₂ emulsions remained nearly unaltered, dropping by only 0.86%, significantly outperforming the conjugates and physical mixture of IMO and EWP in terms of encapsulation stability. The emulsion-gels system was constructed by adding 5% gelatin in the W₁, and had the highest EE% and good salt and heat stability after 30 days of storage. This experiment provides guidance for improving the stability of W₁/O/W₂ emulsions system and its application in the package delivery of functional substances in the food field. Full article

Environmental impact assessment (EIA) performance has remained of interest, and over the past ten years, the evaluation technique has evolved. Thailand implemented an EIA with a health impact assessment (HIA) as an environmental health impact assessment (EHIA), which necessitated investigating and developing these instruments; however, its implementation performance has been questioned. The main goal of this study is to comparatively assess how well EIAs and EHIAs are performed in projects in an area in Thailand. Six projects in various sectors that were implemented in Eastern Thailand were studied. The 162 residents (nine local authorities and 153 villagers) closest to the project completed a survey and evaluated the performance according to three aspects (i.e., substantive, procedural, and transactive), using a rating scale and evaluation checklists. The results were presented as a percentage of the total scores and interpreted according to the five scales. The overall performance reached a satisfactory level, albeit not significantly different between cases; however, it was pointed out that the shortcomings of EHIAs and EIAs, particularly their dependability, lack of public involvement, and the need for more transparency, could be addressed through the establishment of an open access database, which would help to simplify the assessment of all stages of EIAs and EHIAs. Full article