Search Results (1,317)

Converting marine biowaste into nano-bioproducts for their application as bio-sourced, circular biostimulants to enhance crop productivity is a promising approach. This study evaluated chitosan–TPP nanoparticles (nanochitosan, ~38 nm) derived from blue crab (Callinectes sapidus) shells as a soil-applied biostimulant and conditioner for tomato (Solanum lycopersicum) grown in loam soil without mineral fertilizer. Our results showed that nanochitosan application as a soil supplement by drench improved the soil moisture content (39% vs. 22%), water-holding capacity (84% vs. 70%), total nitrogen (3.8 vs. 1.4 gm N kg⁻¹), and organic carbon content (48.4 vs. 34.1 gm C kg⁻¹) in nanochitosan-amended soil compared with the non-amended soil. This was accompanied by higher biomass, better root/shoot development and synthesis of phytohormones leading to increased shoot length, early flowering, and increased total soluble solids of fruits in nanochitosan-amended soil compared with control, suggesting that nanochitosan can act both as a beneficial soil conditioner and as a plant biostimulant. The results further show that nanochitosan-based formulations may be used not only as fertilizer-saving bio-inputs but also as bio-based nanochitosan plant biostimulants, which can partly substitute mineral fertilizer application for sustainable production of tomato. Moreover, generic fabrication of such nanochitosan from marine biowaste would support the circular-bioeconomy model to further improve sustainability of agroecosystems. Full article

Contamination of heavy metals, particularly chromium from industrial activities, represents a critical challenge for public health and the environment. The aim of this study is to evaluate the adsorption performance of green mesoporous silica (GMS-24 h), synthesized through a sustainable process from industrial sodium silicate, and its derivative functionalized with amino groups (GMS-24 h–NH₂) for the removal of Cr(III) in aqueous systems. FTIR and CP–MAS NMR characterization confirmed the surface modification and textural property improvement of green mesoporous silica. The adsorption experiments, carried out under varying pH and Cr(III) concentration conditions, were fitted to the Langmuir and Freundlich models. The results showed that GMS-24 h reached a maximum capacity of 303 mg·g⁻¹ at pH 3, while GMS-24 h–NH₂ achieved 370 mg·g⁻¹ at pH 5. The evaluated adsorbents showed up to a 44% increase in efficiency. Preliminary kinetic studies indicated that the pseudo-second-order model accurately describes the process (R² > 0.99), with the rapid stabilization of the system. Diffusion analysis indicated combined mechanisms, with an additional chelation step (N → Cr) in GMS-24 h–NH₂. These findings suggest that GMS–NH₂ has the potential to be a sustainable and economical adsorbent for the remediation of wastewater from the tanning industry in León, Guanajuato, Mexico. Full article

To address the freeze-thaw (F-T) durability of concrete structures in severely cold plateau regions, this study investigates recycled coarse aggregate concrete (RCAC) by designing mixtures with varying replacement ratios of recycled brick aggregate (RBA). Rapid freeze-thaw cycling tests are conducted in combination with macro- and microscale analytical techniques to systematically elucidate the frost resistance and damage mechanisms of mixed recycled coarse aggregate concrete. When the RBA content is 50%, the concrete demonstrates relatively better frost resistance within the mixed recycled aggregate system. This is evidenced by the lowest mass loss rate coupled with the highest retention ratios for both the relative dynamic elastic modulus (RDEM) and the compressive strength. Micro-analysis indicates that an appropriate amount of RBA can optimize the pore structure, exerting a “micro air-cushion” buffering effect. Blending RBA with recycled concrete aggregate (RCA) may create functional complementarity between pores and the skeleton, effectively delaying freeze–thaw damage. A GM (1,1) damage prediction model based on gray system theory is established, which demonstrates high accuracy (R² > 0.92). This study provides a reliable theoretical basis and a predictive tool for the durability design and service life assessment of mixed recycled coarse aggregate concrete engineering in severely cold regions. Full article

To assess the market competitiveness of high-speed rail (HSR) express and forecast its freight volume, this paper develops an integrated framework combining strategic analysis, market forecasting, and competition assessment. A hybrid SWOT-AHP model identifies and quantifies key strategic factors, clarifying HSR express positioning. Considering macroeconomic and consumption factors, a GM(1,N) model forecasts intercity express volume. Based on a generalized cost function covering timeliness, economy, safety, and stability, an improved Logit model calculates HSR’s mode share against road and air express, deriving future HSR freight volume. Using China as a case study, results show: (1) A proactive strategy leveraging intrinsic strengths is recommended, supported by rapid intercity express growth; (2) HSR can capture over 20% mode share initially, showing strong competitiveness in medium-long distance transport; (3) Transport cost is the most sensitive factor, a 20% reduction raises mode share by 10%, while rising timeliness demands enhance long distance advantages. This study offers a quantitative basis for HSR express strategic planning. Full article

Background: Non-specific low back pain (NSLBP) is associated with altered neuromuscular control of the lumbopelvic–hip complex (LPHC). However, the functional behavior of the transversus abdominis (TrA) and gluteus medius (GM) during upright postural tasks, with and without the abdominal drawing-in maneuver (ADIM), remains unclear. This study aimed to compare TrA and GM activation between individuals with NSLBP and asymptomatic controls during standing and single-leg stance using rehabilitation ultrasound imaging (RUSI). Methods: Thirty-two participants (16 with NSLBP and 16 asymptomatic controls) underwent RUSI assessment under four task conditions: standing and single-leg stance, with and without ADIM. Muscle function was quantified using thickness change derived from ultrasound measurements. A two-way mixed-model analysis of variance with Bonferroni-adjusted post hoc comparisons was performed. Results: Significant group × condition interactions were identified for TrA activation (p < 0.05). Individuals with NSLBP demonstrated reduced TrA activation during standing with ADIM and reduced GM activation during single-leg stance compared with asymptomatic controls. The effect sizes were moderate to large for TrA activation and small to moderate for GM activation. Conclusions: These findings suggest task-specific differences in neuromuscular activation patterns in individuals with NSLBP. Ultrasound-derived thickness change measures obtained during functional, weight-bearing tasks may provide clinically relevant information to support motor control rehabilitation strategies. Full article

Global environmental changes significantly alter ecosystem services (ESs), particularly in fragile regions like the Tibetan Plateau. While methodological advances have improved spatial assessment capabilities, understanding of how multiple drivers interact to shape ecosystem service heterogeneity remains limited to regional scales, especially across complex alpine landscapes. This study aims to clarify whether multi-factor interactions produce nonlinear enhancements in ES explanatory power and how these driver–response relationships vary across heterogeneous terrains. We quantified spatiotemporal patterns of four key ecosystem services—water yield (WY), soil conservation (SC), carbon sequestration (CS), and habitat quality (HQ)—across the southeastern Tibetan Plateau from 2000 to 2020 using multi-source remote sensing data and spatial econometric modeling. Our analysis reveals that SC increased by 0.43 t·hm⁻²·yr⁻¹, CS rose by 1.67 g·m⁻²·yr⁻¹, and HQ improved by 0.09 over this period, while WY decreased by 3.70 mm·yr⁻¹. ES variations are predominantly shaped by potent synergies, where interactive explanatory power consistently surpasses individual drivers. Hydrothermal coupling (precipitation ∩ potential evapotranspiration) reached 0.52 for WY and SC, while climate–vegetation synergy (precipitation ∩ normalized difference vegetation index) achieved 0.76 for CS. Such climate–restoration synergies now fundamentally shape the region’s ESs. Geographically weighted regression (GWR) further revealed distinct spatial dependencies, with southeastern regions experiencing strong negative effects of land use type and elevation on WY, while northwestern areas showed a positive elevation associated with WY but negative effects on SC and HQ. These findings highlight the critical importance of accounting for spatial non-stationarity in driver–ecosystem service relationships when designing conservation strategies for vulnerable alpine ecosystems. Full article

Background/Objectives: Hepatocellular carcinoma (HCC) is one of the most common causes of cancer and cancer-related death worldwide. Beyond the well-known factors influencing the risk of HCC, experimental data from animal models and observational human studies support a significant role of the gut microbiota (GM) in HCC initiation and progression. Dysbiosis and increased intestinal permeability synergistically disrupt the ‘gut–liver axis,’ exposing the liver to bacterial metabolites and microbial-associated molecular patterns, thereby contributing to hepatocarcinogenesis. While these findings have expanded our understanding of HCC pathogenesis, a critical translational gap persists as most data derive from preclinical settings, with limited validation in large-scale clinical studies. Methods: This narrative review aimed to contextualise the current evidence on the GM-HCC axis and its clinical translatability. A literature search was conducted in PubMed/MEDLINE, Scopus, and Web of Science up to July 2025 using Medical Subject Headings and related keywords, including HCC, GM, dysbiosis, intestinal permeability, gut–liver axis, microbial metabolites, inflammation/immune modulation, and microbiota-targeted interventions (probiotics, antibiotics, and faecal microbiota transplantation). Reference lists of relevant articles were also screened to identify additional studies. Results: Preclinical models consistently indicate that dysbiosis and impaired gut barrier function can promote hepatic inflammation, immune dysregulation, and pro-tumorigenic signalling through microbe-derived products and metabolite perturbations, supporting a contributory role of the GM in hepatocarcinogenesis. In humans, HCC and advanced chronic liver disease are associated with altered microbial composition and function, increased markers of intestinal permeability, and changes in bile acid and other metabolite profiles; however, reported signatures are heterogeneous across cohorts and analytical platforms. Conclusions: The GM is a biologically plausible and experimentally supported contributor to HCC initiation and progression, with potential for biomarker development and therapeutic targeting. However, clinical translation is limited by predominantly preclinical/associative evidence, interindividual variability, and non-standardised microbiome methods. Large longitudinal studies and adequately powered randomised trials are needed to establish causality, validate biomarkers, and determine whether GM modulation improves HCC prevention, detection, stratification, or outcomes. Full article

For modern radars with high resolutions, an extended target may generate more than one observations. The conventional point target-based tracking method can hardly be applied in such scenarios. Recently, the ET-GM-PHD approach has been presented for tracking these extended targets. The performance of such an approach has been influenced by the following disadvantages. First, it has been formulated under the linear Gaussian assumptions. When targets move with nonlinear models, the tracking performance may be rapidly decreased. Second, it neglects the time associations of the estimated states at different time steps, which makes it very challenging to manage targets for the radar systems. In this paper, we present a labeled ET-GM-PHD approach based on the square root cubature information filter (SRCIF) to solve such problems. To be more specific, we, first, utilize the SCRIF for predicting and updating the GM components of the ET-GM-PHD approach. For decreasing the computational cost, a candidate observation extracting method has been put forward in the GM component updating step. Thus, the ET-GM-PHD approach can be adopted to track extended targets with nonlinear motions. Second, a label-based trajectory constructing method has been proposed. By assigning the GM components with different labels before the GM component predicting step, we can obtain the estimated states with different labels. On this basis, the associations between the estimated states and trajectories can be modeled based on these labels. Thus, we can obtain the states and trajectories of multi extended targets simultaneously. The simulation results prove the effectiveness of our approach. Full article

Background: Our study aimed to investigate whether the general movements assessment (GMA) and Amiel-Tison Neurologic Examination performed at term-equivalent age (TEA) and 12 weeks corrected age (CA) could predict the occurrence of cerebral palsy (CP) and delayed gross motor milestones in a sample of term and preterm infants and whether the predictive values could be increased by using the two examinations during the same visit. Methods: A total of 70 infants (62 preterm and 8 at term) were examined at TEA and 12 weeks CA using GMs (General Movements) and Amiel-Tison (AT) examinations. We determined the correlation between the results of the examinations and several selected items (scarf sign, popliteal angle, and axial tone) and neuromotor outcomes (presence of cerebral palsy (CP), independent sitting, and independent walking). We attempted to build binary logistic regression models using items from both examination techniques to assess whether the combined use of the two exams could have a better predictive value than using one technique alone. Results: We analyzed the entire group and, separately, the subgroup of preterm infants. For the whole group, there was a statistically significant correlation between the GM examinations at TEA and 12 weeks CA (p < 0.008) as well as between the results of GM and AT exams performed at TEA (p < 0.001) and 12 weeks CA (p < 0.001). The strongest individual predictor for CP in the whole group was the absence of fidgety movements at 12 weeks CA (AUC (Area Under the Curve) = 0.873; CI (confidence interval) 95%: 0.748–0.998; p < 0.001) and a non-optimal result at the synthesis of findings of AT exam at 12 weeks CA (AUC = 0.755; CI 95%: 0.617–0.892; p < 0.003). In the subgroup of 62 premature neonates, absent fidgety movements at 12 weeks CA (AUC = 0.925; CI 95%: 0.819–1.031; p < 0.001) and a non-optimal result in the synthesis of findings of AT exam at 12 weeks CA (AUC = 0.772; CI 95%: 0.620–0.924; p < 0.005) were statistically significant predictors for the risk of CP. In the case of delayed sitting and delayed/absent walking, absent fidgety movements and non-optimal results in the AT exam at TEA and 12 weeks CA were the strongest individual predictors in the whole group as well as in the subgroup of preterm infants. The following exploratory logistic regression models reached statistical significance: one model combining absent fidgety + abnormal scarf sign + abnormal popliteal angle at 12 weeks CA for CP in the whole group (p < 0.032) and preterm infants (p < 0.034) and for delayed sitting in preterm infants (p < 0.041) and a second model combining absent fidgety + abnormal scarf + abnormal popliteal + abnormal axial + abnormal synthesis for CP risk (p < 0.046) and delayed sitting (p < 0.001) in preterm infants at 12 weeks CA. Conclusions: The absence of fidgety movements at 12 weeks CA represented the strongest individual predictor for the occurrence of CP and delayed gross motor milestones in our sample, both in the whole group and the subgroup of preterm infants. The combination of GM and AT findings reached statistical significance for the detection of CP risk in the whole group and CP risk and delayed sitting in the subgroup of preterm infants. Due to sample size limitations, the results should be regarded with caution, and larger studies are needed before robust conclusions can be drawn. Full article

The variable-pitch connecting rod of a helicopter bears axial tensile and compressive loads during operation. The traditional load monitoring method using strain gauge is easily affected by external conditions. Therefore, a giant magnetostrictive (GM) tension and compression force sensor with permanent magnet bias is proposed and optimized. Because the bias magnetic field plays a decisive role in the performance of the sensor, this paper has carried out in-depth research on this. Firstly, the mathematical model of the magnetic circuit is established, and the various magnetic circuits of the sensor are simulated and analyzed. Secondly, the magnetic flux uniformity of the GMM rod is used as the evaluation index, and the relative permeability of the magnetic material and the structure are systematically studied. The influence of parameters on the magnetic flux of the magnetic circuit, and finally the optimal parameter combination of the magnetic circuit is determined by orthogonal test. The results show that when the magnetic circuit without the magnetic side wall is used, the magnetic material can better guide the magnetic flux through the GMM rod; the magnetic flux uniformity of the optimized GMM force sensor is increased by 7.44%, the magnetic flux density is increased by 13.9 mT and the Hall output voltage increases linearly by 1.125% in the same proportion. This provides an important reference for improving the utilization rate of GMM rods and also improves the safety of flight operation and reduces maintenance costs. Full article

China is a major global marine fishing country, and exploring the sustainable development potential of its marine fisheries is critical to the global fisheries sector’s Blue Transformation. Based on sustainable development connotations, this study adopts the GM(1,1) model and entropy weight-TOPSIS model to predict and evaluate the marine fisheries’ sustainable development potential from 2021 to 2030, building an evaluation framework spanning economic, social, and resource-environmental dimensions. The results show an overall upward trend in the sustainable development potential during the period, with a notable 2022 trough driven by the COVID-19 pandemic, policy transitions, and complex international conditions. As adverse factors ease and long-term policies advance, the potential will continue to improve steadily. Finally, targeted policy recommendations are proposed, focusing on industrial transformation, technological innovation, resource-environment conservation, and factor guarantee to facilitate the sector’s sustainable development and Blue Transformation. Full article

Background/Objectives: Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality worldwide, with its development influenced by diet, obesity, and gut microbiota (GM) alterations. This study aimed to evaluate the impact of human fecal microbiota transplantation (FMT) on the progression of CRC in a murine model. Methods: CRC was chemically induced in BALB/c mice using azoxymethane/dextran sulfate sodium (AOM/DSS). Mice were transferred with GM via FMT and divided into two experimental groups according to the microbiota source (healthy donors or CRC patients). A positive control group (AOM/DSS without FMT) and a negative control group (no CRC induction or FMT) were included. Clinical parameters, histopathological analyses, and cytokine profiling were performed. Results: Mice receiving FMT, particularly from CRC patients, exhibited increased mitotic activity, dysplasia, neoplastic proliferation, structural alterations in the colon, and more pronounced GALT hyperplasia. At the immunological level, both FMT groups (healthy and CRC-derived) showed modulation of IL-1β, IL-4, IL-6, IL-10, IL-17A, and TNF-α compared to the positive control. Conclusions: Human GM transplantation modulated the colonic microenvironment through histopathological and immunological changes, influencing CRC progression in this murine model. These findings highlight the role of GM in shaping CRC development and suggest that human-derived microbiota may significantly impact tumor dynamics. Full article

Land use systems are closely coupled with socioeconomic activities. To explore the interactions between land use and socioeconomic activities in Bazhong City, clarify the characteristics, drivers, and future trends of land use change, and provide scientific support for optimizing regional land resource allocation, ecological conservation, and food security, this study analyzes land cover data from 2004 to 2024, identifies economic drivers via principal component analysis, and predicts future land use trends for 2025, 2030, and 2035 using the GM(1,1) model. The results indicate the following: (1) Cropland decreased by 1338.69 km², while forest increased by 1304.88 km², with the largest area of mutual conversion occurring between these two types. (2) The comprehensive index of land use exhibited a fluctuating decline. The quality and continuity of cropland decreased, while the expansion of forest increased ecosystem services. (3) Principal component analysis identified the Comprehensive Economic Development and Urbanization Factor (e.g., GDP, urbanization rate, etc.) as the long-term core driver, with the land use driving system evolving through three stages. (4) Projections indicate that forest will increase, while cropland will decrease by 263.83 km². While the cropland is projected to remain above the planned target by 2035, the persistent downward trend will nonetheless pose a threat to food security. This study provides insights for harmonizing land use planning with socioeconomic progress and ecological conservation with cropland protection and may also serve as a reference for related decision-making in similar regions. Full article

Concrete structures in western saline soil regions are subjected to extreme environments with coupled dry-wet cycles and high concentrations of erosive ions such as Cl⁻, SO₄²⁻, and Mg²⁺, leading to severe degradation of mechanical properties. This study employed a simulated accelerated, high-concentration solution (Solution A, ~8× seawater salinity) similar to the composition of actual saline soil to perform accelerated dry-wet cycling corrosion tests on ordinary C40 concrete specimens for six corrosion ages (0, 5, 8, 10, 15, and 20 months). For each age, three replicate cube specimens were tested per property. The changes in cube compressive strength, splitting tensile strength, prism stress–strain full curves, and microstructure were systematically investigated. Results show that in the initial corrosion stage (0–5 months), strength exhibits a brief increase (compressive strength by 11.87%, splitting tensile strength by 9.23%) due to pore filling by corrosion products such as ettringite, gypsum, and Friedel’s salt. It then enters a slow deterioration stage (5–15 months), with significant strength decline by 20 months, where splitting tensile strength is most sensitive to corrosion. Long-term prediction models for key parameters such as compressive strength, splitting tensile strength, elastic modulus, peak stress, and peak strain were established based on grey GM(1,1) theory using the measured data from 0 to 20 months, achieving “excellent” accuracy (C ≤ 0.1221, p = 1). A segmented compressive constitutive model that considers the effect of corrosion time was proposed by combining continuous damage mechanics and the Weibull distribution. The ascending branch showed high consistency with the experimental curves. Life prediction indicates that under natural dry-wet cycling conditions, the service life of ordinary concrete in this region is only about 7.5 years when splitting tensile strength drops to 50% of initial value as the failure criterion, far below the 50-year design benchmark period. This study provides reliable theoretical models and a quantitative basis for durability design and life assessment of concrete structures in western saline soil regions. Full article

Peat, a vital component of horticultural growing media (GM), is recognized by the Intergovernmental Panel on Climate Change (IPCC) as a solid fossil fuel which significantly contributes to the depletion of fossil resources and greenhouse gas emissions. This study evaluated the partial replacement of peat with three locally available by-products—wood fiber (WF), coffee silverskin (CS), and brewers’ spent grain (BSG)—in the cultivation of potted ornamental sage through an integrated environmental–economic approach. Ten GM formulations were modeled, with peat substitutions ranging from 0 to 40% (v/v) across one hectare of greenhouse production (90,000 pots). Environmental impacts were assessed using the EPD 2018 method in SimaPro, while eco-efficiency was calculated as the ratio of the environmental impact costs resulting from the different energy consumptions (EUR) to related revenues (EUR). Results revealed only minor variations among impact categories when comparing the alternative growing media with the peat-based control (0PR), with the exception of the Abiotic Depletion of Fossil Fuels (ADff), which showed a consistent decrease at higher peat replacement levels. Treatments with 40% substitution performed best, particularly BSG40 and CS40, with the lowest eco-efficiency ratios (≈approximately 11.4%). WF40 also showed favorable outcomes (≈12.7%), confirming that a 20–40% peat replacement offers the optimal balance between environmental sustainability and economic viability. Overall, partial peat replacement using local by-products effectively reduces the consumption of fossil resources without significantly impacting other environmental indicators, promoting circularity and competitiveness in ornamental plant production. Full article