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  • Article
  • Open Access
5 Citations
3,353 Views
13 Pages

Structural Analysis and Anti-Inflammatory Effect of a Digalactosyldiacylglycerol-Monoestolide, a Characteristic Glycolipid in Oats

  • Hiroki Yamada,
  • Junya Ito,
  • Naoki Shimizu,
  • Takumi Takahashi,
  • Chikara Kato,
  • Isabella Supardi Parida,
  • Mirinthorn Jutanom,
  • Katsuyuki Ishihara and
  • Kiyotaka Nakagawa

6 October 2022

Digalactosyldiacylglycerol- (DGDG-) monoestolide is a characteristic glycolipid in oats. DGDG-monoestolides possess a unique structure whereby a fatty acid of DGDG is replaced by a fatty acid ester of hydroxy fatty acid (FAHFA). While the physiologic...

  • Feature Paper
  • Article
  • Open Access
3 Citations
3,920 Views
14 Pages

29 September 2022

Laminaria hyperborea (Gunnerus) Foslie 1885 is a seaweed native to the North Atlantic, which is utilized in the production of alginate. Its potential as a source of bioactive lipids remains unexplored. In this study, mono- and digalactosyldiacylglyce...

  • Article
  • Open Access
12 Citations
5,817 Views
18 Pages

13 July 2020

Glyceroglycolipids, abundant in cyanobacteria’s photosynthetic membranes, present bioactivities and pharmacological activities, and can be widely used in the pharmaceutical industry. Environmental factors could alter the contents and compositio...

  • Article
  • Open Access
5 Citations
1,789 Views
16 Pages

Changes in Polar Lipid Composition in Balsam Fir during Seasonal Cold Acclimation and Relationship to Needle Abscission

  • Mason T. MacDonald,
  • Rajasekaran R. Lada,
  • Gaye E. MacDonald,
  • Claude D. Caldwell and
  • Chibuike C. Udenigwe

28 October 2023

Needle abscission in balsam fir has been linked to both cold acclimation and changes in lipid composition. The overall objective of this research is to uncover lipid changes in balsam fir during cold acclimation and link those changes with postharves...

  • Article
  • Open Access
1,830 Views
14 Pages

Epidermal and Blood Vessel Barrier Functions of Glucosylceramides and Digalactosyldiacylglycerols Isolated from Yellow Strawberry Guava

  • Akari Yoneda,
  • Shogo Takeda,
  • Kenchi Miyasaka,
  • Yoshiaki Manse,
  • Toshio Morikawa and
  • Hiroshi Shimoda

8 July 2024

Strawberry guava is the fruit of Psidium littorale, which grows in tropical regions. Few studies have examined the hydrophobic compounds and biological activities of this fruit. Therefore, we purified lipophilic compounds of strawberry guava and exam...

  • Article
  • Open Access
3 Citations
3,009 Views
15 Pages

Oxygen Exposure and Tolerance Shapes the Cell Wall-Associated Lipids of the Skin Commensal Cutibacterium acnes

  • Iuliana Popa,
  • David Touboul,
  • Tilde Andersson,
  • Eduardo Fuentes-Lemus,
  • Cyrille Santerre,
  • Michael J. Davies and
  • Rolf Lood

Cutibacterium acnes is one of the most abundant bacteria on the skin. Being exposed to oxygen and oxic stress, the secretion of the bacterial antioxidant protein RoxP ensures an endogenous antioxidant system for the preservation of skin health. To in...

  • Article
  • Open Access
8 Citations
3,004 Views
19 Pages

29 June 2022

The effect of temperature and light intensity on the polar lipidome of endophytic brown algae Streblonema corymbiferum and Streblonema sp. in vitro was investigated. More than 460 molecular species have been identified in four glycoglycerolipids clas...

  • Article
  • Open Access
7 Citations
4,721 Views
11 Pages

2 February 2019

The red macroalga Agarophyton chilensis is a well-known producer of eicosanoids such as hydroxyeicosatetraenoic acids, but the alga produces almost no prostaglandins, unlike the closely related A. vermiculophyllum. This indicates that the related two...

  • Article
  • Open Access
3 Citations
2,747 Views
13 Pages

28 February 2024

Floridoside is a galactosyl–glycerol compound that acts to supply UDP-galactose and functions as an organic osmolyte in response to salinity in Rhodophyta. Significantly, the UDP-galactose pool is shared for sulfated cell wall galactan synthesi...

  • Review
  • Open Access
28 Citations
7,424 Views
17 Pages

20 September 2019

Galactolipids, monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG), are the predominant lipid classes in the thylakoid membrane of chloroplasts. These lipids are also major constituents of internal membrane structures called pro...

  • Article
  • Open Access
16 Citations
6,481 Views
18 Pages

Combined Effects of Ozone and Drought on the Physiology and Membrane Lipids of Two Cowpea (Vigna unguiculata (L.) Walp) Cultivars

  • Deborah Moura Rebouças,
  • Yuri Maia De Sousa,
  • Matthieu Bagard,
  • Jose Helio Costa,
  • Yves Jolivet,
  • Dirce Fernandes De Melo and
  • Anne Repellin

3 March 2017

The interactive effects of drought and ozone on the physiology and leaf membrane lipid content, composition and metabolism of cowpea (Vigna unguiculata (L.) Walp.) were investigated in two cultivars (EPACE-1 and IT83-D) grown under controlled conditi...

  • Article
  • Open Access
38 Citations
14,126 Views
21 Pages

13 June 2020

The brown alga Fucus vesiculosus is common to the intertidal zones of the Baltic Sea, where it is exposed to high fouling pressures by microorganisms. Our previous studies showed, repeatedly, the consistent antimicrobial activity of F. vesiculosus cr...

  • Article
  • Open Access
12 Citations
3,883 Views
17 Pages

Coral Holobionts Possess Distinct Lipid Profiles That May Be Shaped by Symbiodiniaceae Taxonomy

  • Tatyana V. Sikorskaya,
  • Ekaterina V. Ermolenko,
  • Kseniya V. Efimova and
  • Ly T. P. Dang

28 July 2022

Symbiotic relationships are very important for corals. Abiotic stressors cause the acclimatization of cell membranes in symbionts, which possess different membrane acclimatization strategies. Membrane stability is determined by a unique lipid composi...

  • Article
  • Open Access
6 Citations
2,458 Views
14 Pages

Glycerol-3-Phosphate Acyltransferase GPAT9 Enhanced Seed Oil Accumulation and Eukaryotic Galactolipid Synthesis in Brassica napus

  • Wei Gong,
  • Wenling Chen,
  • Qiang Gao,
  • Lei Qian,
  • Xueyuan Yuan,
  • Shaohua Tang and
  • Yueyun Hong

9 November 2023

Glycerol-3-phosphate acyltransferase GPAT9 catalyzes the first acylation of glycerol-3-phosphate (G3P), a committed step of glycerolipid synthesis in Arabidopsis. The role of GPAT9 in Brassica napus remains to be elucidated. Here, we identified four...

  • Article
  • Open Access
18 Citations
3,989 Views
18 Pages

Polar Lipids of Marine Microalgae Nannochloropsis oceanica and Chlorococcum amblystomatis Mitigate the LPS-Induced Pro-Inflammatory Response in Macrophages

  • Tiago Conde,
  • Bruno Neves,
  • Daniela Couto,
  • Tânia Melo,
  • Diana Lopes,
  • Rita Pais,
  • Joana Batista,
  • Helena Cardoso,
  • Joana Laranjeira Silva and
  • M. Rosário Domingues
  • + 1 author

6 December 2023

Microalgae are recognized as a relevant source of bioactive compounds. Among these bioactive products, lipids, mainly glycolipids, have been shown to present immunomodulatory properties with the potential to mitigate chronic inflammation. This study...

  • Article
  • Open Access
11 Citations
3,431 Views
15 Pages

31 March 2021

Monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG) are the main constituent lipids of thylakoid and chloroplast envelop membranes. Many microalgae can accumulate large amounts of triacylglycerols (TAGs) under adverse environmen...

  • Article
  • Open Access
8 Citations
3,294 Views
22 Pages

13 February 2023

Sulfur (S) deprivation leads to abiotic stress in plants. This can have a significant impact on membrane lipids, illustrated by a change in either the lipid class and/or the fatty acid distribution. Three different levels of S (deprivation, adequate,...

  • Article
  • Open Access
6 Citations
2,589 Views
13 Pages

Lipidome Profiling of Phosphorus Deficiency-Tolerant Rice Cultivars Reveals Remodeling of Membrane Lipids as a Mechanism of Low P Tolerance

  • Soichiro Honda,
  • Yumiko Yamazaki,
  • Takumi Mukada,
  • Weiguo Cheng,
  • Masaru Chuba,
  • Yozo Okazaki,
  • Kazuki Saito,
  • Akira Oikawa,
  • Hayato Maruyama and
  • Keitaro Tawaraya
  • + 2 authors

18 March 2023

Plants have evolved various mechanisms for low P tolerance, one of which is changing their membrane lipid composition by remodeling phospholipids with non-phospholipids. The objective of this study was to investigate the remodeling of membrane lipids...

  • Article
  • Open Access
3 Citations
3,062 Views
22 Pages

Differential Membrane Lipid Profiles and Vibrational Spectra of Three Edaphic Algae and One Cyanobacterium

  • Olimpio Montero,
  • Marta Velasco,
  • Jorge Miñón,
  • Evan A. N. Marks,
  • Aurelio Sanz-Arranz and
  • Carlos Rad

19 October 2021

The membrane glycerolipids of four phototrophs that were isolated from an edaphic assemblage were determined by UPLC–MS after cultivation in a laboratory growth chamber. Identification was carried out by 18S and 16S rDNA sequencing. The algal species...

  • Article
  • Open Access
4 Citations
3,879 Views
18 Pages

25 June 2021

The aims of this work were to evaluate the contribution of the free fatty acid (FA) pool to triacylglyceride (TAG) biosynthesis and to try to characterize the mechanism by which FA are assimilated into TAG in the green alga Dunaliella tertiolecta. A...

  • Article
  • Open Access
21 Citations
4,261 Views
20 Pages

Metabolic Regulation and Lipidomic Remodeling in Relation to Spermidine-induced Stress Tolerance to High Temperature in Plants

  • Zhou Li,
  • Bizhen Cheng,
  • Yue Zhao,
  • Lin Luo,
  • Yan Zhang,
  • Guangyan Feng,
  • Liebao Han,
  • Yan Peng and
  • Xinquan Zhang

13 October 2022

Beneficial effects of spermidine (Spd) on alleviating abiotic stress damage have been explored in plants for hundreds of years, but limited information is available about its roles in regulating lipids signaling and metabolism during heat stress. Whi...

  • Article
  • Open Access
19 Citations
4,906 Views
13 Pages

29 May 2020

The Arabidopsis has 51 proteins annotated as serine carboxypeptidase-like (SCPL) enzymes. Although biochemical and cellular characterization indicates SCPLs involved in protein turnover or processing, little is known about their roles in plant metabo...

  • Article
  • Open Access
8 Citations
3,141 Views
14 Pages

Preliminary Analysis, Combined with Omics of Chilling Injury Mechanism of Peach Fruits with Different Cold Sensitivities during Postharvest Cold Storage

  • Wenduo Zhan,
  • Yan Wang,
  • Wenyi Duan,
  • Ang Li,
  • Yule Miao,
  • Hongmei Wang,
  • Junren Meng,
  • Hui Liu,
  • Liang Niu and
  • Wenfang Zeng
  • + 4 authors

The storage of peach fruits at 4–5 °C can easily lead to chilling injury and greatly reduce the quality and commercial value of peach fruits. In this study, two kinds of peach fruits (CX and CM) were selected to analyze the mechanisms of ch...

  • Review
  • Open Access
41 Citations
14,390 Views
32 Pages

Anticancer and Immunomodulatory Benefits of Taro (Colocasia esculenta) Corms, an Underexploited Tuber Crop

  • Patrícia Ribeiro Pereira,
  • Érika Bertozzi de Aquino Mattos,
  • Anna Carolina Nitzsche Teixeira Fernandes Corrêa,
  • Mauricio Afonso Vericimo and
  • Vania Margaret Flosi Paschoalin

29 December 2020

Taro corms contain valuable bioactive molecules effective against cancer and cancer-related risk factors, such as carcinogens and biological agents, several pathophysiological conditions, including oxidative stress and inflammation, while controlling...

  • Review
  • Open Access
121 Citations
16,029 Views
27 Pages

Lipidomic Approaches towards Deciphering Glycolipids from Microalgae as a Reservoir of Bioactive Lipids

  • Elisabete Da Costa,
  • Joana Silva,
  • Sofia Hoffman Mendonça,
  • Maria Helena Abreu and
  • Maria Rosário Domingues

19 May 2016

In recent years, noteworthy research has been performed around lipids from microalgae. Among lipids, glycolipids (GLs) are quite abundant in microalgae and are considered an important source of fatty acids (FAs). GLs are rich in 16- and 18-carbon sat...

  • Article
  • Open Access
11 Citations
4,394 Views
17 Pages

15 March 2021

Ilex × altaclerensis ‘Belgica Aurea’ is an attractive ornamental plant bearing yellow-green variegated leaves. However, the mechanisms underlying the formation of leaf variegation in this species are still unclear. Here, the juvenile yellow leaves an...

  • Article
  • Open Access
14 Citations
3,519 Views
19 Pages

Effect of Drought Stress on Degradation and Remodeling of Membrane Lipids in Nostoc flagelliforme

  • Meng Wang,
  • Qiang Zhu,
  • Xiaoxu Li,
  • Jinhong Hu,
  • Fan Song,
  • Wangli Liang,
  • Xiaorong Ma,
  • Lingxia Wang and
  • Wenyu Liang

18 June 2022

Nostoc flagelliforme is a kind of terrestrial edible cyanobacteria with important ecological and economic value which has developed special mechanisms to adapt to drought conditions. However, the specific mechanism of lipidome changes in drought tole...

  • Article
  • Open Access
4 Citations
2,576 Views
16 Pages

OsMGD1-Mediated Membrane Lipid Remodeling Improves Salt Tolerance in Rice

  • Shasha Li,
  • Lei Hui,
  • Jingchong Li,
  • Yuan Xi,
  • Jili Xu,
  • Linglong Wang and
  • Lina Yin

27 May 2024

Salt stress severely reduces photosynthetic efficiency, resulting in adverse effects on crop growth and yield production. Two key thylakoid membrane lipid components, monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG), were per...

  • Article
  • Open Access
822 Views
19 Pages

Melatonin Improves Drought Stress Tolerance by Remodeling Lipid Metabolism in Setaria italica L.

  • Jianhong Ren,
  • Tao Zhang,
  • Xin Yin,
  • Yijia Zhao,
  • Fanyi Meng and
  • Xiaoxiao Yang

30 October 2025

Membrane lipid remodeling represents a crucial adaptive mechanism for plants in response to drought stress. This study investigated the regulatory influence of melatonin on the photosynthetic attributes, oxidative damage, and lipid metabolism of foxt...

  • Article
  • Open Access
22 Citations
5,569 Views
19 Pages

Modulation of Polar Lipid Profiles in Chlorella sp. in Response to Nutrient Limitation

  • Daniel A. White,
  • Paul A. Rooks,
  • Susan Kimmance,
  • Karen Tait,
  • Mark Jones,
  • Glen A. Tarran,
  • Charlotte Cook and
  • Carole A. Llewellyn

28 February 2019

We evaluate the effects of nutrient limitation on cellular composition of polar lipid classes/species in Chlorella sp. using modern polar lipidomic profiling methods (liquid chromatography–tandem mass spectrometry; LC-MS/MS). Total polar lipid...

  • Article
  • Open Access
17 Citations
58,581 Views
17 Pages

21 September 2017

Ceramides are known to play a key role in the skin’s barrier function. An age-dependent decrease in ceramides content correlates with cutaneous clinical signs of dryness, loss of elasticity, and increased roughness. The present placebo-controlled cli...

  • Article
  • Open Access
484 Views
17 Pages

29 November 2025

Despite the nutritional importance of sweetpotato, systematic studies on its lipid metabolism remain largely unexplored. To address this gap, this study investigates the dynamic changes in lipid composition during the development of sweetpotato stora...

  • Article
  • Open Access
51 Citations
7,517 Views
15 Pages

8 July 2020

Chilling injury is especially prominent in postharvest bananas stored at low temperature below 13 °C. To elucidate better the relationship between cell membrane lipids and chilling injury, an untargeted lipidomics approach using ultra-performance...

  • Article
  • Open Access
4 Citations
3,010 Views
15 Pages

Semi-Targeted Profiling of the Lipidome Changes Induced by Erysiphe Necator in Disease-Resistant and Vitis vinifera L. Varieties

  • Ramona Mihaela Ciubotaru,
  • Mar Garcia-Aloy,
  • Domenico Masuero,
  • Pietro Franceschi,
  • Luca Zulini,
  • Marco Stefanini,
  • Michael Oberhuber,
  • Peter Robatscher,
  • Giulia Chitarrini and
  • Urska Vrhovsek

17 February 2023

The ascomycete Erysiphe necator is a serious pathogen in viticulture. Despite the fact that some grapevine genotypes exhibit mono-locus or pyramided resistance to this fungus, the lipidomics basis of these genotypes’ defense mechanisms remains...

  • Article
  • Open Access
14 Citations
3,499 Views
17 Pages

Grape Lipidomics: An Extensive Profiling thorough UHPLC-MS/MS Method

  • Domenico Masuero,
  • Domen Škrab,
  • Giulia Chitarrini,
  • Mar Garcia-Aloy,
  • Pietro Franceschi,
  • Paolo Sivilotti,
  • Graziano Guella and
  • Urska Vrhovsek

30 November 2021

Lipids play many essential roles in living organisms, which accounts for the great diversity of these amphiphilic molecules within the individual lipid classes, while their composition depends on intrinsic and extrinsic factors. Recent developments i...

  • Article
  • Open Access
2 Citations
1,295 Views
17 Pages

13 June 2025

Light is a source of energy for photosynthesis and hence promotes the regulation of multiple physiological and metabolic processes in photoautotrophic organisms. Understanding how brown macrophytes adjust the physical and biochemical properties of ph...

  • Article
  • Open Access
45 Citations
6,452 Views
23 Pages

Carbon Nanoparticles Functionalized with Carboxylic Acid Improved the Germination and Seedling Vigor in Upland Boreal Forest Species

  • Md. Hossen Ali,
  • Jean-Marie Sobze,
  • Thu Huong Pham,
  • Muhammad Nadeem,
  • Chen Liu,
  • Lakshman Galagedara,
  • Mumtaz Cheema and
  • Raymond Thomas

20 January 2020

Nanopriming has been shown to significantly improve seed germination and seedling vigor in several agricultural crops. However, this approach has not been applied to native upland boreal forest species with complex seed dormancy to improve propagatio...

  • Article
  • Open Access
1,104 Views
17 Pages

Transcriptomic and Lipidomic Analysis Reveals the Regulatory Network of Lipid Metabolism in Cannabis sativa

  • Bowei Yan,
  • Chuanyi Chang,
  • Yue Sui,
  • Nan Zheng,
  • Yuyan Fang,
  • Yuanye Zhang,
  • Ming Zhang,
  • Dan He and
  • Liguo Zhang

13 August 2025

Hemp possesses significant healthcare value due to its rich composition of unsaturated fatty acids and a distinctive golden ratio of linoleic acid to α-linolenic acid. As a promising special-oil crop, it holds substantial potential for developm...

  • Feature Paper
  • Article
  • Open Access
83 Citations
9,841 Views
17 Pages

Valorization of Lipids from Gracilaria sp. through Lipidomics and Decoding of Antiproliferative and Anti-Inflammatory Activity

  • Elisabete Da Costa,
  • Tânia Melo,
  • Ana S. P. Moreira,
  • Carina Bernardo,
  • Luisa Helguero,
  • Isabel Ferreira,
  • Maria Teresa Cruz,
  • Andreia M. Rego,
  • Pedro Domingues and
  • Maria Rosário Domingues
  • + 2 authors

2 March 2017

The lipidome of the red seaweed Gracilaria sp., cultivated on land-based integrated multitrophic aquaculture (IMTA) system, was assessed for the first time using hydrophilic interaction liquid chromatography-mass spectrometry and tandem mass spectrom...

  • Article
  • Open Access
25 Citations
4,306 Views
16 Pages

Lipidomics of the Edible Brown Alga Wakame (Undaria pinnatifida) by Liquid Chromatography Coupled to Electrospray Ionization and Tandem Mass Spectrometry

  • Davide Coniglio,
  • Mariachiara Bianco,
  • Giovanni Ventura,
  • Cosima D. Calvano,
  • Ilario Losito and
  • Tommaso R. I. Cataldi

24 July 2021

The lipidome of a brown seaweed commonly known as wakame (Undaria pinnatifida), which is grown and consumed around the world, including Western countries, as a healthy nutraceutical food or supplement, was here extensively examined. The study was foc...

  • Article
  • Open Access
9 Citations
2,412 Views
19 Pages

RNA-Seq Identified Putative Genes Conferring Photosynthesis and Root Development of Melon under Salt Stress

  • Tai Liu,
  • Sikandar Amanullah,
  • Huichun Xu,
  • Peng Gao,
  • Zhiqiang Du,
  • Xixi Hu,
  • Mo Han,
  • Ye Che,
  • Ling Zhang and
  • Di Wang
  • + 1 author

29 August 2023

Melon is an important fruit crop of the Cucurbitaceae family that is being cultivated over a large area in China. Unfortunately, salt stress has crucial effects on crop plants and damages photosynthesis, membranal lipid components, and hormonal metab...

  • Article
  • Open Access
38 Citations
5,549 Views
19 Pages

Domesticated Populations of Codium tomentosum Display Lipid Extracts with Lower Seasonal Shifts than Conspecifics from the Wild—Relevance for Biotechnological Applications of this Green Seaweed

  • Felisa Rey,
  • Paulo Cartaxana,
  • Tânia Melo,
  • Ricardo Calado,
  • Rui Pereira,
  • Helena Abreu,
  • Pedro Domingues,
  • Sónia Cruz and
  • M. Rosário Domingues

31 March 2020

In the last decades, the use of algae in biotechnology and food industries has experienced an exponential growth. Codium tomentosum is a green macroalgae with high biotechnological potential, due to its rich lipidome, although few studies have addres...

  • Article
  • Open Access
251 Views
16 Pages

20 January 2026

Dichondra (Dichondra repens) is an important thermophilic Chinese herbal medicine and a key component in traditional herbal tea and beverages. It is also commonly used as an excellent ground cover plant for landscapes and cover cropping in orchards....

  • Article
  • Open Access
1 Citations
2,468 Views
50 Pages

The rapid regulatory mechanism of light-induced state transitions (STs) in oxygenic photosynthesis is particularly appealing for membrane-based applications. This interest stems from the unique ability of the thylakoid membrane protein cytochrome b6f...