5 Results Found

Advanced Search

Select all

Results per page

Select all

Article

47 Citations

10,036 Views

14 Pages

Cytotoxic Podophyllotoxin Type-Lignans from the Steam Bark of Bursera fagaroides var. fagaroides

Andrés M. Rojas-Sepúlveda,
Mario Mendieta-Serrano,
Mayra Y. Antúnez Mojica,
Enrique Salas-Vidal,
Silvia Marquina,
María Luisa Villarreal,
Ana María Puebla,
Jorge I. Delgado and
Laura Alvarez

Molecules2012, 17(8), 9506-9519;https://doi.org/10.3390/molecules17089506

9 August 2012

The hydroalcoholic extract of the steam bark of B. fagaroides var. fagaroides displayed potent cytotoxic activity against four cancer cell lines, namely KB (ED50 = 9.6 × 10−2 μg/mL), PC-3 (ED50 = 2.5 × 10−1 μg/mL), MCF-7 (ED50 = 6.6 μg/mL), and HF-6...

Full Article

Article

14 Citations

5,351 Views

12 Pages

Antigiardial Activity of Podophyllotoxin-Type Lignans from Bursera fagaroides var. fagaroides

Filiberto Gutiérrez-Gutiérrez,
Ana María Puebla-Pérez,
Sirenia González-Pozos,
José Manuel Hernández-Hernández,
Armando Pérez-Rangel,
Laura Patricia Alvarez,
Gabriela Tapia-Pastrana and
Araceli Castillo-Romero

Molecules2017, 22(5), 799;https://doi.org/10.3390/molecules22050799

13 May 2017

Giardiasis, a diarrheal disease, is highly prevalent in developing countries. Several drugs are available for the treatment of this parasitosis; unfortunately, all of them have variable efficacies and adverse effects. Bursera fagaroides has been know...

Full Article

Article

2 Citations

2,489 Views

15 Pages

In Vitro Anti-Tubulin Activity on MCF10A Cell Line and In Silico Rigid/Semiflexible-Residues Docking, of Two Lignans from Bursera Fagaroides var. Fagaroides

Verónica Rodríguez-López,
César Millán-Pacheco,
Judith González-Christen,
Maricruz Anaya-Ruíz and
Omar Aristeo Peña-Morán

Molecules2021, 26(20), 6155;https://doi.org/10.3390/molecules26206155

12 October 2021

Podophyllotoxins are natural lignans with known cytotoxic activity on several cell lines. The structural basis for their actions is mainly by the aryltetralin-lignan skeleton. Authors have proposed a cytotoxic mechanism of podophyllotoxins through th...

Full Article

Article

213 Citations

9,785 Views

15 Pages

Cytotoxicity, Post-Treatment Recovery, and Selectivity Analysis of Naturally Occurring Podophyllotoxins from Bursera fagaroides var. fagaroides on Breast Cancer Cell Lines

Omar Aristeo Peña-Morán,
María Luisa Villarreal,
Laura Álvarez-Berber,
Angélica Meneses-Acosta and
Verónica Rodríguez-López

Molecules2016, 21(8), 1013;https://doi.org/10.3390/molecules21081013

4 August 2016

Despite prevention and treatment options, breast cancer (BC) has become one of the most important issues in the present day. Therefore, the need for more specific and efficient compounds remains paramount. We evaluated four previously isolated arylte...

Full Article

Article

64 Citations

14,200 Views

9 Pages

Germacrene D, A Common Sesquiterpene in the Genus Bursera (Burseraceae)

Koji Noge and
Judith X. Becerra

Molecules2009, 14(12), 5289-5297;https://doi.org/10.3390/molecules14125289

15 December 2009

The volatile components of the leaves of five Bursera species, B. copallifera, B. exselsa, B. mirandae, B. ruticola and B. fagaroides var. purpusii were determined by gas chromatography–mass spectrometry (GC–MS). Germacrene D was one of the predomina...

Full Article