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Search Results (481)

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16 pages, 3189 KiB  
Article
Improved Block Element Method for Simulating Rock Failure
by Yan Han, Qingwen Ren, Lei Shen and Yajuan Yin
Appl. Sci. 2025, 15(15), 8636; https://doi.org/10.3390/app15158636 - 4 Aug 2025
Viewed by 126
Abstract
As a discontinuous deformation method, the block element method (BEM) characterizes a material’s elastoplastic behavior through the constitutive relation of thin-layer elements between adjacent blocks. To realistically simulate rock damage paths, this work improves the traditional BEM by using random Voronoi polygonal grids [...] Read more.
As a discontinuous deformation method, the block element method (BEM) characterizes a material’s elastoplastic behavior through the constitutive relation of thin-layer elements between adjacent blocks. To realistically simulate rock damage paths, this work improves the traditional BEM by using random Voronoi polygonal grids for discrete modeling. This approach mitigates the distortion of damage paths caused by regular grids through the randomness of the Voronoi grids. As the innovation of this work, the iterative algorithm is combined with polygonal geometric features so that the area–perimeter fractal dimension can be introduced to optimize random Voronoi grids. The iterative control index can effectively improve the geometric characteristics of the grid while maintaining the necessary randomness. On this basis, a constitutive relation model that considers both normal and tangential damage is proposed. The entire process from damage initiation to macroscopic fracture failure in rocks is described using two independent damage surfaces and a damage relationship based on geometric mapping relationships. The analysis results are in good agreement with existing experimental data. Furthermore, the sensitivity method is used to analyze the influence of key mechanical parameters in the constitutive model. Full article
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34 pages, 7297 KiB  
Article
Passive Design for Residential Buildings in Arid Desert Climates: Insights from the Solar Decathlon Middle East
by Esra Trepci and Edwin Rodriguez-Ubinas
Buildings 2025, 15(15), 2731; https://doi.org/10.3390/buildings15152731 - 2 Aug 2025
Viewed by 339
Abstract
This study investigates the effectiveness of passive design in low-rise residential buildings located in arid desert climates, using the Dubai Solar Decathlon Middle East (SDME) competition as a case study. This full-scale experiment offers a unique opportunity to evaluate design solutions under controlled, [...] Read more.
This study investigates the effectiveness of passive design in low-rise residential buildings located in arid desert climates, using the Dubai Solar Decathlon Middle East (SDME) competition as a case study. This full-scale experiment offers a unique opportunity to evaluate design solutions under controlled, realistic conditions; prescriptive, modeled performance; and monitored performance assessments. The prescriptive assessment reviews geometry, orientation, envelope thermal properties, and shading. Most houses adopt compact forms, with envelope-to-volume and envelope-to-floor area ratios averaging 1 and 3.7, respectively, and window-to-wall ratios of approximately 17%, favoring north-facing openings to optimize daylight while reducing heat gain. Shading is strategically applied, horizontal on south façades and vertical on east and west. The thermal properties significantly exceed the local code requirements, with wall performance up to 80% better than that mandated. The modeled assessment uses Building Energy Models (BEMs) to simulate the impact of prescriptive measures on energy performance. Three variations are applied: assigning minimum local code requirements to all the houses to isolate the geometry (baseline); removing shading; and applying actual envelope properties. Geometry alone accounts for up to 60% of the variation in cooling intensity; shading reduces loads by 6.5%, and enhanced envelopes lower demand by 14%. The monitored assessment uses contest-period data. Indoor temperatures remain stable (22–25 °C) despite outdoor fluctuations. Energy use confirms that houses with good designs and airtightness have lower cooling loads. Airtightness varies widely (avg. 14.5 m3/h/m2), with some well-designed houses underperforming due to construction flaws. These findings highlight the critical role of passive design as the first layer for improving the energy performance of the built environment and advancing toward net-zero targets, specifically in arid desert climates. Full article
(This article belongs to the Special Issue Climate-Responsive Architectural and Urban Design)
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24 pages, 3598 KiB  
Article
State of the Art on Empirical and Numerical Methods for Cave Stability Analysis: Application in Al-Badia Lava Tube, Harrat Al-Shaam, Jordan
by Ronald Herrera, Daniel Garcés, Abdelmadjid Benrabah, Ahmad Al-Malabeh, Rafael Jordá-Bordehore and Luis Jordá-Bordehore
Appl. Mech. 2025, 6(3), 56; https://doi.org/10.3390/applmech6030056 - 31 Jul 2025
Viewed by 106
Abstract
Empirical and numerical methodologies for the geomechanical assessment of underground excavations have evolved in recent years to adapt to the geotechnical and structural conditions of natural caves, enabling stability evaluation and ensuring safe conditions for speleological exploration. This study analyzes the evolution of [...] Read more.
Empirical and numerical methodologies for the geomechanical assessment of underground excavations have evolved in recent years to adapt to the geotechnical and structural conditions of natural caves, enabling stability evaluation and ensuring safe conditions for speleological exploration. This study analyzes the evolution of the state of the art of these techniques worldwide, assessing their reliability and application context, and identifying the most suitable methodologies for determining the stability of the Al-Badia lava tube. The research was conducted through bibliographic analysis and rock mass characterization using empirical geomechanical classifications. Subsequently, the numerical boundary element method (BEM) was applied to compare the obtained results and model the stress–strain behavior of the cavity. The results allowed the classification of the Al-Badia lava tube into stable, transition, and unstable zones, using empirical support charts and determining the safety factors of the surrounding rock mass. The study site highlights that empirical methods are rather conservative, and numerical results align better with observed conditions. Full article
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32 pages, 6657 KiB  
Article
Mechanisms of Ocean Acidification in Massachusetts Bay: Insights from Modeling and Observations
by Lu Wang, Changsheng Chen, Joseph Salisbury, Siqi Li, Robert C. Beardsley and Jackie Motyka
Remote Sens. 2025, 17(15), 2651; https://doi.org/10.3390/rs17152651 - 31 Jul 2025
Viewed by 316
Abstract
Massachusetts Bay in the northeastern United States is highly vulnerable to ocean acidification (OA) due to reduced buffering capacity from significant freshwater inputs. We hypothesize that acidification varies across temporal and spatial scales, with short-term variability driven by seasonal biological respiration, precipitation–evaporation balance, [...] Read more.
Massachusetts Bay in the northeastern United States is highly vulnerable to ocean acidification (OA) due to reduced buffering capacity from significant freshwater inputs. We hypothesize that acidification varies across temporal and spatial scales, with short-term variability driven by seasonal biological respiration, precipitation–evaporation balance, and river discharge, and long-term changes linked to global warming and river flux shifts. These patterns arise from complex nonlinear interactions between physical and biogeochemical processes. To investigate OA variability, we applied the Northeast Biogeochemistry and Ecosystem Model (NeBEM), a fully coupled three-dimensional physical–biogeochemical system, to Massachusetts Bay and Boston Harbor. Numerical simulation was performed for 2016. Assimilating satellite-derived sea surface temperature and sea surface height improved NeBEM’s ability to reproduce observed seasonal and spatial variability in stratification, mixing, and circulation. The model accurately simulated seasonal changes in nutrients, chlorophyll-a, dissolved oxygen, and pH. The model results suggest that nearshore areas were consistently more susceptible to OA, especially during winter and spring. Mechanistic analysis revealed contrasting processes between shallow inner and deeper outer bay waters. In the inner bay, partial pressure of pCO2 (pCO2) and aragonite saturation (Ωa) were influenced by sea temperature, dissolved inorganic carbon (DIC), and total alkalinity (TA). TA variability was driven by nitrification and denitrification, while DIC was shaped by advection and net community production (NCP). In the outer bay, pCO2 was controlled by temperature and DIC, and Ωa was primarily determined by DIC variability. TA changes were linked to NCP and nitrification–denitrification, with DIC also influenced by air–sea gas exchange. Full article
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21 pages, 1661 KiB  
Article
Performance Assessment of B-Series Marine Propellers with Cupping and Face Camber Ratio Using Machine Learning Techniques
by Mina Tadros and Evangelos Boulougouris
J. Mar. Sci. Eng. 2025, 13(7), 1345; https://doi.org/10.3390/jmse13071345 - 15 Jul 2025
Viewed by 384
Abstract
This study investigates the performance of B-series marine propellers enhanced through geometric modifications, namely face camber ratio (FCR) and cupping percentage modifications, using a machine learning (ML)-driven optimization framework. A large dataset of over 7000 open-water propeller configurations is curated, incorporating variations in [...] Read more.
This study investigates the performance of B-series marine propellers enhanced through geometric modifications, namely face camber ratio (FCR) and cupping percentage modifications, using a machine learning (ML)-driven optimization framework. A large dataset of over 7000 open-water propeller configurations is curated, incorporating variations in blade number, expanded area ratio (EAR), pitch-to-diameter ratio (P/D), FCR, and cupping percentage. A multi-layer artificial neural network (ANN) is trained to predict thrust, torque, and open-water efficiency (ηo) with a high coefficient of determination (R2), greater than 0.9999. The ANN is integrated into an optimization algorithm to identify optimal propeller designs for the KRISO Container Ship (KCS) using empirical constraints for cavitation and tip speed. Unlike prior studies that rely on boundary element method (BEM)-ML hybrids or multi-fidelity simulations, this study introduces a geometry-coupled analysis of FCR and cupping—parameters often treated independently—and applies empirical cavitation and acoustic (tip speed) limits to guide the design process. The results indicate that incorporating 1.0–1.5% cupping leads to a significant improvement in efficiency, up to 9.3% above the reference propeller, while maintaining cavitation safety margins and acoustic limits. Conversely, designs with non-zero FCR values (0.5–1.5%) show a modest efficiency penalty (up to 4.3%), although some configurations remain competitive when compensated by higher EAR, P/D, or blade count. The study confirms that the combination of cupping with optimized geometric parameters yields high-efficiency, cavitation-safe propellers. Furthermore, the ML-based framework demonstrates excellent potential for rapid, accurate, and scalable propeller design optimization that meets both performance and regulatory constraints. Full article
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28 pages, 4519 KiB  
Article
HBIM-Based Multicriteria Method for Assessing Internal Insulation in Heritage Buildings
by Angelo Massafra, Luca Mattioli, Iuliia Kozlova, Cecilia Mazzoli, Giorgia Predari and Riccardo Gulli
Heritage 2025, 8(7), 259; https://doi.org/10.3390/heritage8070259 - 1 Jul 2025
Viewed by 397
Abstract
Energy retrofitting of historic buildings presents complex challenges, particularly when using internal insulation strategies. While such interventions can enhance thermal comfort and reduce energy demand, they can also pose risks of condensation and mold formation, thereby reducing usable space. This paper proposes an [...] Read more.
Energy retrofitting of historic buildings presents complex challenges, particularly when using internal insulation strategies. While such interventions can enhance thermal comfort and reduce energy demand, they can also pose risks of condensation and mold formation, thereby reducing usable space. This paper proposes an evaluation methodology for assessing the performance of internal insulating panels within a multicriteria framework to support decision-making during the design phase. The approach, scalable to various contexts, is grounded in a digital workflow that integrates heritage building information modeling (HBIM), visual programming (VP), and building energy modeling (BEM) to create a decision-support tool for renovation designers. The methodology, tested on a building located in Bologna (Italy), allows for assessing internal insulation systems with varying thermophysical properties and performance characteristics, and evaluating how they affect space- and wall-level key performance indicators, including condensation risk, energy efficiency improvement, and usable space reduction. The research was conducted under the Horizon Europe HERIT4AGES project, which aims to develop reversible, innovative insulation panels fabricated from local and recycled materials for historic building retrofitting. Full article
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29 pages, 3288 KiB  
Article
A BEM Adjoint-Based Differentiable Shape Optimization of a Stealth Aircraft
by Charles Thoulon, Gilbert Roge and Olivier Pironneau
Eng 2025, 6(7), 147; https://doi.org/10.3390/eng6070147 - 1 Jul 2025
Viewed by 243
Abstract
Modern fighter aircraft have an increasing need for at least a moderate level of stealth, and the shape design must bear a part of this constraint. However, the high frequency of close range radar makes high-fidelity radar cross-section computation methods such as the [...] Read more.
Modern fighter aircraft have an increasing need for at least a moderate level of stealth, and the shape design must bear a part of this constraint. However, the high frequency of close range radar makes high-fidelity radar cross-section computation methods such as the boundary element method too expensive to use in a gradient-free optimization process. On the other hand, asymptotic methods are not able to accurately predict the RCS of complex shapes such as intake cavities. Hence, the need arises for efficient and accurate methods to compute the gradient of high-fidelity radar cross-section computation methods with respect to shape parameters. In this paper, we propose an adjoint formulation for the boundary element method to efficiently compute these gradients. We present a novel approach to calculate the gradient of high-fidelity radar cross-section computations using the boundary element method. Our method employs an adjoint formulation that allows for the efficient computation of these gradients. This is particularly beneficial in shape optimization problems where accurate and efficient methods are crucial to designing modern fighter aircraft with stealth capabilities. By avoiding the need for solving the actual adjoint problem in certain cases, our formulation provides a more streamlined solution while still maintaining high accuracy. We demonstrate the effectiveness of our method by performing shape optimization on various shapes, including simple geometries like spheres and ellipsoids, as well as complex aircraft shapes with multiple variables. Full article
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31 pages, 802 KiB  
Review
Impact of EU Laws on the Adoption of AI and IoT in Advanced Building Energy Management Systems: A Review of Regulatory Barriers, Technological Challenges, and Economic Opportunities
by Bo Nørregaard Jørgensen and Zheng Grace Ma
Buildings 2025, 15(13), 2160; https://doi.org/10.3390/buildings15132160 - 21 Jun 2025
Cited by 1 | Viewed by 854
Abstract
The integration of Artificial Intelligence (AI) and the Internet of Things (IoT) in Building Energy Management Systems (BEMSs) offers transformative potential for improving energy efficiency, enhancing occupant comfort, and supporting grid stability. However, the adoption of these technologies in the European Union (EU) [...] Read more.
The integration of Artificial Intelligence (AI) and the Internet of Things (IoT) in Building Energy Management Systems (BEMSs) offers transformative potential for improving energy efficiency, enhancing occupant comfort, and supporting grid stability. However, the adoption of these technologies in the European Union (EU) is significantly influenced by a complex regulatory landscape, including the EU AI Act, the General Data Protection Regulation (GDPR), the EU Cybersecurity Act, and the Energy Performance of Buildings Directive (EPBD). This review systematically examines the legal, technological, and economic implications of these regulations on AI- and IoT-driven BEMS. Following the PRISMA-ScR guidelines, 64 relevant sources were reviewed, comprising 34 peer-reviewed articles and 30 regulatory or policy documents. First, legal and regulatory barriers that may hinder innovation are identified, including data protection constraints, cybersecurity compliance, liability concerns, and interoperability requirements. Second, technological challenges in designing regulatory-compliant AI and IoT solutions are examined, with a focus on data privacy-preserving architectures (e.g., edge computing versus cloud processing), explainability requirements for AI decision-making, and cybersecurity resilience. Finally, the economic opportunities arising from regulatory alignment are highlighted, demonstrating how compliant AI and IoT-based BEMS can enable energy savings, operational efficiencies, and new business models in smart buildings. By synthesizing current research and policy developments, this review offers a comprehensive framework for understanding the intersection of regulatory requirements and technological innovation in AI-driven building management. Strategies are discussed for navigating regulatory constraints while leveraging AI and IoT for energy-efficient, intelligent building operations. The insights presented aim to support researchers, policymakers, and industry stakeholders in advancing regulatory-compliant BEMS that balance innovation, security, and sustainability. Full article
(This article belongs to the Section Building Energy, Physics, Environment, and Systems)
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13 pages, 2360 KiB  
Article
New Bayesian Estimation Method Based on Symmetric Projection Space and Particle Flow Velocity
by Juan Tan, Zijun Wu and Lijuan Chen
Symmetry 2025, 17(6), 899; https://doi.org/10.3390/sym17060899 - 6 Jun 2025
Viewed by 365
Abstract
Aiming at the state estimation problem of nonlinear systems (NLSs), the traditional typical nonlinear filtering methods (e.g., Particle Filter, PF) have large errors in system state, resulting in low accuracy and high computational speed. To perfect the imperfections, a new Bayesian estimation method [...] Read more.
Aiming at the state estimation problem of nonlinear systems (NLSs), the traditional typical nonlinear filtering methods (e.g., Particle Filter, PF) have large errors in system state, resulting in low accuracy and high computational speed. To perfect the imperfections, a new Bayesian estimation method based on particle flow velocity (PFV-BEM) is proposed in this paper. Firstly, a symmetrical projection space based on the state information is selected, the basis function is determined by a set of Fourier series with symmetric properties, the state update is carried out according to the projection principle to calculate the prior information of the state, and select its particle points. Secondly, the particle flow velocity is defined, which describes the evolution process of random samples from the prior distribution to the posterior distribution. The posterior information of the state is calculated by solving the parameters related to the particle flow velocity. Finally, the estimated mean and standard deviation of the state are solved. Simulation experiments are carried out based on two instances of one-dimensional general nonlinear examples and multi-target motion tracking, The newly proposed algorithm is compared with the Particle Filter (PF), and the simulation results clearly indicate the feasibility of this novel Bayesian estimation algorithm. Full article
(This article belongs to the Section Mathematics)
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32 pages, 11638 KiB  
Article
Solar Heat Gain Simulations for Energy-Efficient Guest Allocation in a Large Hotel Tower in Madrid
by Iker Landa del Barrio, Markel Flores Iglesias, Juan Odriozola González, Víctor Fabregat and Jan L. Bruse
Buildings 2025, 15(11), 1960; https://doi.org/10.3390/buildings15111960 - 5 Jun 2025
Viewed by 489
Abstract
The current climate and energy crises demand innovative approaches to operating buildings more sustainably. HVAC systems, which significantly contribute to a building’s energy consumption, have been a major focus of research aimed at improving operational efficiency. However, a critical factor often overlooked is [...] Read more.
The current climate and energy crises demand innovative approaches to operating buildings more sustainably. HVAC systems, which significantly contribute to a building’s energy consumption, have been a major focus of research aimed at improving operational efficiency. However, a critical factor often overlooked is the seasonal and hourly variation in solar radiation and the resulting solar heat gain, which heats specific rooms differently depending on their orientation, type, and location within the building. This study proposes a simulation-based strategy to reduce HVAC energy use in hotels by allocating guests to rooms with more favorable thermal characteristics depending on the season. A high-resolution building energy model (BEM) was developed to represent a real 17-floor hotel tower in Madrid, incorporating detailed geometry and surrounding shading context. The model includes 439 internal thermal zones and simulates solar radiation using EnergyPlus’ Radiance module. The simulation results revealed large room-by-room differences in thermal energy demand. When applying an energetically optimized guest allocation strategy based on these simulations and using real occupancy data, potential reductions in HVAC energy demand were estimated to reach around 6% during summer and up to 20% in winter. These findings demonstrate that data-driven guest allocation, informed by physics-based building simulations, can provide substantial energy savings without requiring physical renovations or equipment upgrades, offering a promising approach for more sustainable hotel operation. Full article
(This article belongs to the Special Issue Research on Advanced Technologies Applied in Green Buildings)
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27 pages, 2239 KiB  
Article
Propeller Design Optimization and an Evaluation of Variable Rotational Speed Flight Operation Under Structural Vibration Constraints
by Nicolas Lima Oliveira, Afonso Celso de Castro Lemonge, Patricia Habib Hallak, Konstantinos Kyprianidis, Stavros Vouros and Manuel A. Rendón
Machines 2025, 13(6), 490; https://doi.org/10.3390/machines13060490 - 5 Jun 2025
Viewed by 629
Abstract
This paper presents a methodology for optimizing an aeronautical propeller to minimize power consumption. A multi-objective approach using blade element momentum (BEM) theory and evolutionary algorithms is employed to optimize propeller design by minimizing power consumption during takeoff and top-of-climb. Three different evolutionary [...] Read more.
This paper presents a methodology for optimizing an aeronautical propeller to minimize power consumption. A multi-objective approach using blade element momentum (BEM) theory and evolutionary algorithms is employed to optimize propeller design by minimizing power consumption during takeoff and top-of-climb. Three different evolutionary algorithms generated a Pareto front, from which the optimal propeller design is selected. The selected propeller design is evaluated under optimal operational conditions for a specific mission. In this context, two operational approaches for the optimized propellers during flight missions are evaluated. The first approach considers the possibility of only three values for the propeller rotation, while the second allows continuous changes in the rotational speed and pitch angle values, known as the multi-rotational-speed approach. In the second approach, a modal analysis of the propeller is performed using rotating beam theory. The natural frequencies of vibration, constrained by the Campbell diagram, enable an operational analysis and ensure structural integrity by preventing resonance between propeller blades and the rotational procedures. The multi-rotational approach is conducted with and without frequency constraints, resulting in general flight energy reductions of 1.40% and 1.47%, respectively. However, substantial power savings are achieved, namely up to 10% during critical flight states, which can have a significant impact on future engine design and operability. The main contributions of the research lie in analyzing the multi-rotational approach with vibrational constraints of the optimized propeller. This research advances sustainable aviation practices by focusing on reducing power consumption while maintaining performance. Full article
(This article belongs to the Section Turbomachinery)
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25 pages, 1184 KiB  
Article
Influence of Bragg Resonance on the Hydrodynamic Performance of a Fixed-Detached Asymmetric Oscillating Water Column Device
by Prakash Kar, Robert Mayon and Dezhi Ning
J. Mar. Sci. Eng. 2025, 13(6), 1115; https://doi.org/10.3390/jmse13061115 - 2 Jun 2025
Viewed by 491
Abstract
The present study analyzes the hydrodynamic performance of an asymmetric offshore Oscillating Water Column device positioned in close proximity to multiple bottom standing and fully submerged breakwaters and trenches. The breakwaters and trenches are located on the leeward side of the Oscillating Water [...] Read more.
The present study analyzes the hydrodynamic performance of an asymmetric offshore Oscillating Water Column device positioned in close proximity to multiple bottom standing and fully submerged breakwaters and trenches. The breakwaters and trenches are located on the leeward side of the Oscillating Water Column device. The structures are investigated in combination with a shore-fixed vertical wall. The analysis is carried out using the Boundary Element Method based on the linear potential flow theory. The results are compared with the existing analytical, numerical, and experiment results available in the literature. The effects of the various shape parameters of the submerged breakwaters/trenches and the shape parameters of the Oscillating Water Column device are investigated. The results show that the resonance effects on the efficiency performance increase as the number of breakwaters/trenches increases. The undulating bottom trench shape is effective in improving the efficiency of the Oscillating Water Column device compared to the breakwater. The efficiency bandwidth is greater in the case of a rectangular trench than in the case of a parabolic- or triangular-shaped trench. In addition, the first peak value in the efficiency curve for a lower frequency is higher in the case of a larger-draft Oscillating Water Column device front wall compared to that of the rear wall. This study demonstrates that in the long wave-length regime, a zero efficiency point is observed between two consecutive resonant peaks, whereas in the intermediate and short wave-length regimes, a trough and a zero efficiency point alternately occur between two consecutive resonance peaks. Various parameters relevant to the behavior of the Oscillating Water Column Wave Energy Converter, such as radiation susceptance, radiation conductance, hydrodynamic efficiency, and volume flux due to a scatter potential, are addressed. Full article
(This article belongs to the Topic Marine Renewable Energy, 2nd Edition)
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27 pages, 9598 KiB  
Article
Optimization of Calibration Settings for Passive Anti-Islanding Protections Using a Bayesian Entropy Methodology to Support the Sustainable Integration of Renewable Distributed Generation
by Eduardo Marcelo Seguin Batadi, Marcelo Gustavo Molina and Maximiliano Martínez
Sustainability 2025, 17(11), 4859; https://doi.org/10.3390/su17114859 - 26 May 2025
Viewed by 324
Abstract
The global pursuit of sustainable development increasingly depends on integrating renewable energy sources into power systems, with distributed generation (DG) playing a vital role. However, this integration presents technical challenges, particularly the risk of unintentional islanding. Anti-islanding protections are essential for detecting and [...] Read more.
The global pursuit of sustainable development increasingly depends on integrating renewable energy sources into power systems, with distributed generation (DG) playing a vital role. However, this integration presents technical challenges, particularly the risk of unintentional islanding. Anti-islanding protections are essential for detecting and isolating such events, as required by IEEE 1547, within two seconds. Yet, calibrating these protections to balance sensitivity and reliability remains a complex task, as evidenced by incidents like the UK power outage on 9 August 2019 and the Southwestern Utah event on 10 April 2023. This study introduces the Bayesian Entropy Methodology (BEM), an innovative approach that employs entropy as a model for uncertainty in protection decision-making. By leveraging Bayesian inference, BEM identifies optimal calibration settings for time delay and pick-up thresholds, minimizing uncertainty and effectively balancing sensitivity and reliability. The methodology incorporates a modified entropy surface to enhance optimization outcomes. Applied to the IEEE 34-node test system, BEM demonstrates the ability to determine optimal settings with a significantly reduced training dataset, leading to substantial computational savings. By enhancing the reliability of anti-islanding protections, BEM facilitates the secure integration of renewable DG, contributing to the sustainable development of modern power systems. Full article
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16 pages, 1919 KiB  
Article
Retinal Changes in Early-Onset cblC Methylmalonic Acidemia Identified Through Expanded Newborn Screening: Highlights from a Case Study and Literature Review
by Paola Michieletto, Francesco Baldo, Maurizio Madonia, Luisa Zupin, Stefano Pensiero and Maria Teresa Bonati
Genes 2025, 16(6), 635; https://doi.org/10.3390/genes16060635 - 25 May 2025
Viewed by 662
Abstract
Background: Methylmalonic acidemia combined with homocystinuria (cblC) can lead to infantile maculopathy. Although significant visual deterioration is commonly reported in early-onset cblC, we found poor awareness regarding formal assessments of ocular complications, especially in newborns, and of how these complications relate to the [...] Read more.
Background: Methylmalonic acidemia combined with homocystinuria (cblC) can lead to infantile maculopathy. Although significant visual deterioration is commonly reported in early-onset cblC, we found poor awareness regarding formal assessments of ocular complications, especially in newborns, and of how these complications relate to the timing of therapy initiation. In this work, we present our experience and perform a literature review. Methods: We performed sequential fundus examinations, optical coherence tomography (OCT) and full-field electroretinography (ERG) under sedation following detection of signs of retinal degeneration. We also assessed visual fields using kinetic attraction perimetry. Results: We report a newborn who was referred on the eighth day of life, following a diagnosis of cblC through newborn screening (NBS), and who began treatment that same day. Close monitoring of retinal changes through fundus examinations allowed the detection of signs of retinal degeneration at 3 months, which progressed when checked at 5 months. At 7 months, OCT showed retinal thinning with the appearance of bull’s eye maculopathy in the corresponding region on fundoscopy; ERG revealed a reduction in the amplitude of both scotopic and photopic components, whereas kinetic attraction perimetry showed no abnormalities. Genetic investigation confirmed the disease, compound heterozygous for a nonsense variant in MMACHC and a splicing one in PRDX1. Conclusions: In cblC, retinal degeneration occurs in the first months of life despite timely treatment and adequate biochemical control, and it may manifest before any signs of visual deprivation appear. However, there is an early, narrow window during which therapy may slow down retinal degeneration enough to prevent sensory nystagmus. We recommend initiating therapy immediately after biochemical diagnosis, along with close ophthalmological monitoring, before the appearance of any signs. Full article
(This article belongs to the Section Molecular Genetics and Genomics)
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27 pages, 2622 KiB  
Article
Enhancing Interoperability Between Building Information Modeling and Building Energy Modeling: Alphanumerical Information Exchange for Energy Optimization in Early Design Stages
by Josef Miller, Larissa Schneiderbauer, Martin Hauer, Alexandra Jäger, Georg Fröch, Rainer Pfluger and Stephan Moser
Appl. Sci. 2025, 15(10), 5789; https://doi.org/10.3390/app15105789 - 21 May 2025
Viewed by 582
Abstract
Building information modeling (BIM) has revolutionized integrated planning by optimizing costs, schedule, and material use. However, building energy modeling (BEM) remains underutilized in early design stages due to interoperability challenges between BIM and BEM tools. This study addresses these challenges by exploring standardized [...] Read more.
Building information modeling (BIM) has revolutionized integrated planning by optimizing costs, schedule, and material use. However, building energy modeling (BEM) remains underutilized in early design stages due to interoperability challenges between BIM and BEM tools. This study addresses these challenges by exploring standardized exchange requirements and introducing a novel toolchain that bridges BIM and BEM workflows. In the BIM2IndiLight project, over 400 standardized properties for daylighting, artificial lighting, and façade systems were validated, revealing the advantages and limitations of parameter standardization. Building on these insights, the BIM2BEM-Flow project developed a three-step toolchain that efficiently manages project- and company-specific properties, defines mapping rules, and integrates parameters via a BIM plugin for validated IFC export. The results demonstrate that combining standardized properties with a flexible, workflow-driven toolchain significantly enhances data exchange and interoperability between BIM and BEM. This integrated approach supports early-stage energy performance optimization and offers a promising pathway toward more efficient design processes in the AECO industry. Full article
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