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Investigation of the Anticancer Effect of α-Aminophosphonates and Arylidine Derivatives of 3-Acetyl-1-aminoquinolin-2(1H)-one on the DMBA Model of Breast Cancer in Albino Rats with In Silico Prediction of Their Thymidylate Synthase Inhibitory Effect
- Mohamed A. Nassan,
- Adil Aldhahrani,
- Hamada H. Amer,
- Ahmed Elhenawy,
- Ayman A. Swelum,
- Omar M. Ali and
- Yasser H. Zaki
Breast cancer is a major cause of death in women worldwide. In this study, 60 female rats were classified into 6 groups; negative control, α-aminophosphonates, arylidine derivatives of 3-acetyl-1-aminoquinolin-2(1H)-one, DMBA, DMBA & &alpha...