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Article

4 Citations

4,118 Views

21 Pages

Structural Studies of the 3′,3′-cGAMP Riboswitch Induced by Cognate and Noncognate Ligands Using Molecular Dynamics Simulation

Chaoqun Li,
Xiaojia Zhao,
Xiaomin Zhu,
Pengtao Xie and
Guangju Chen

Int. J. Mol. Sci.2018, 19(11), 3527;https://doi.org/10.3390/ijms19113527

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9 November 2018

Riboswtich RNAs can control gene expression through the structural change induced by the corresponding small-molecule ligands. Molecular dynamics simulations and free energy calculations on the aptamer domain of the 3′,3′-cGAMP riboswitch...

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Article

2 Citations

4,107 Views

16 Pages

The Signaling Pathway That cGAMP Riboswitches Found: Analysis and Application of Riboswitches to Study cGAMP Signaling in Geobacter sulfurreducens

Zhesen Tan,
Chi Ho Chan,
Michael Maleska,
Bryan Banuelos Jara,
Brian K. Lohman,
Nathan J. Ricks,
Daniel R. Bond and
Ming C. Hammond

Int. J. Mol. Sci.2022, 23(3), 1183;https://doi.org/10.3390/ijms23031183

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21 January 2022

The Hypr cGAMP signaling pathway was discovered via the function of the riboswitch. In this study, we show the development of a method for affinity capture followed by sequencing to identify non-coding RNA regions that bind nucleotide signals such as...

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