Search Results (10,069)

Photocatalytic extraction of uranium from radioactive wastewater is crucial for environmental safety and sustainable nuclear energy development. It is widely recognized that photocatalysts with donor-acceptor (D-A) or D-π-A structures exhibit enhanced charge separation efficiency, thereby showing excellent photocatalytic performance. Herein, we presented a counterintuitive design of a donor-donor covalent-organic framework (D-D COF) for efficient photocatalytic uranium extraction. A twisted D-D COF (COF-BCTB-Py) was synthesized via solvothermal condensation using bicarbazole and pyrene as dual electron-donor units. The COF featured a well-defined AA-stacked porous structure, high specific surface area (963 m²·g⁻¹), suitable band gap (2.44 eV), and exceptional chemical, thermal, and radiation stability. Impressively, in the presence of 5% methanol, it delivered an ultrahigh uranium uptake capacity of 4278 mg·g⁻¹ with fast kinetics and >97% removal efficiency in complex water matrices, challenging the traditional stereotype of low-activity D-D COFs. Mechanistic studies revealed that soluble U(VI) was converted into crystalline (UO₂)O₂·2H₂O via in situ generated hydrogen peroxide rather than being reduced to U(IV). This work provides an unconventional design strategy to design efficient photocatalysts for uranium recovery from nuclear wastewater. Full article

Polycrystalline silicon (poly-Si) is a promising channel material for three-dimensional (3D) stacked memory architecture owing to its process compatibility and excellent manufacturability. However, its practical application is hindered by intrinsic limitations, such as reduced carrier mobility and elevated off-state current (I_off), which originate from localized electric fields and trap states at grain boundaries. In this study, the structural characteristics, including the crystallization behavior and grain morphologies, of silicon films deposited by sputtering and low-pressure chemical vapor deposition (LPCVD) were comparatively investigated. Raman spectroscopy and cross-sectional transmission electron microscopy (TEM) results confirmed that LPCVD poly-Si annealed at 800 °C exhibits over 95% crystallinity and a columnar-like grain structure. Based on this structural superiority, transistor-level electrical characterizations were exclusively conducted on LPCVD-based devices. The results show that the I_off of annealed poly-Si depends on the channel width, with normalized I_off values being lower when the channel is narrower than the average grain size. Further, a larger grain size with a columnar structure in poly-Si can maintain acceptable I_off levels in 3D stacked memory devices incorporating narrow channel widths. Full article

We introduce a single dimensionless landscape function $J_{\mathrm{chem}}\left(\rho \right)=cosh(\rho ln\phi )-1$, with $\phi =(1+\sqrt{5})/2$, defined on the noble gas-centred coordinate $\rho =d/L_p\in [0,1)$, and show that it organizes four central within-period atomic observables, first ionization energy ${\mathrm{IE}}_1$, electron affinity $\mathrm{EA}$, Mulliken electronegativity ${\chi }_M$, and Pearson chemical hardness $\eta$, on a single periodic-table axis. The outward step $\Delta J_{\mathrm{chem}}^{+}$ delivers ${\mathrm{IE}}_1$, the inward gap $\Delta J_{\mathrm{chem}}^{-}=J_{\mathrm{chem}}\left(1\right)-J_{\mathrm{chem}}\left(\rho \right)$ delivers $\mathrm{EA}$ and $\eta$, and ${\chi }_M$ follows from Mulliken’s identity. Benchmarked against NIST and Pearson tabulated atomic data, the framework reproduces the within-period ${\mathrm{IE}}_1$ envelope across periods 2–6 and localizes every upward deviation on the textbook anomaly sites $\{p^3,d^5,f^7,s^2,d^{10}\}$; it yields two parameter-free golden ratio ionization-energy identities (${\phi }^{1/4}$ on heavy noble gas pairs and ${\phi }^2$ on halogen/alkali pairs, agreeing with data to MAD $\approx 1\%$ and $\approx 5\%$); and it provides single-parameter analytical fits for $\mathrm{EA}$ (MAE $0.3$–$0.4$ eV), Pearson hardness $\eta$, and Mulliken ${\chi }_M$ ($R^2=0.73$ on a 15-atom 4-class benchmark). By assembling four periodic-table observables under one golden ratio cosh coordinate, the construction provides a compact analytical reference against which relativistic and shell-anomaly corrections can be quantified. Full article

The demand for large-scale high-performance components with tailored properties in the aerospace and automotive industries has increased interest in multi-material additive manufacturing (AM). Among AM techniques, the Wire Arc Additive Manufacturing (WAAM) process is preferred for bimetallic fabrication due to high deposition rates, low equipment costs, and efficient material utilization. However, differences in metallurgical and thermal properties between dissimilar alloys can cause heat accumulation, leading to thermal stresses, cracking, and weak interfacial bonds. To the best of the authors’ knowledge, no study has reported the fabrication and characterization of a 17-4PH SS/Inconel 625 joint using the large-scale CMT-WAAM Process. To fill this gap, this study characterizes the microstructure and elemental distribution of the joint using scanning electron microscopy (SEM), X-ray diffraction (XRD), X-ray Microscopy (XRM) and energy dispersive spectroscopy (EDS). Microstructural analysis revealed a martensitic matrix with retained δ-ferrite in the 17-4PH region, a fully austenitic γ-phase in the Inconel 625 region, and a mixed BCC–FCC transition zone at the interface. EDS results demonstrated a Fe–Ni compositional gradient across the interface. Radiographic inspection confirmed a defect-free build, and XRM results showed a porosity of less than 0.003% only in the 17-4PH region. Tensile testing confirmed joint integrity, with fracture occurring in the Inconel 625 region, and average yield and ultimate tensile strengths of 391 ± 7 MPa and 676 ± 9 MPa, respectively. The simplified Johnson-Cook constitutive model successfully predicted the ultimate tensile strength (UTS), with a prediction error of 9.3% compared to the experimental result. Furthermore, a novel 3D-structured light scanner technique was developed and validated with an extensometer to provide insight into localized strain behavior. Full article

Conventional photothermal therapy often relies on high-intensity laser excitation due to the limited photothermal conversion efficiency (PCE) of existing photothermal agents (PTAs), which compromises treatment safety and restricts clinical translation. To address this limitation, we designed and synthesized a series of boron-dipyrromethene (BODIPY)-based derivatives (BDP 1–4) featuring gradient-enhanced donor–acceptor (D-A) push–pull electronic effects for efficient photothermal antitumor therapy. The structure–activity relationships were systematically elucidated through photophysical characterization and in vitro/in vivo photobiological evaluation. From BDP 1 to BDP 4, the progressively strengthened push–pull effect leads to enhanced intramolecular charge transfer (ICT), which, in turn, results in a narrowed HOMO-LUMO gap, redshifted absorption into the near-infrared (NIR) region (up to 843 nm), markedly attenuated fluorescence emission, and a remarkable increase in PCE up to 88.3%. To improve water dispersibility and tumor targeting, these molecules were further encapsulated into nanoparticles using DSPE-PEG₂₀₀₀, and the nanoformulations retained high PCE. Both in vitro and in vivo studies demonstrated that under low-power laser irradiation (0.5 W·cm⁻², 808 nm), the nanoformulation of BDP 4, which exhibited the highest PCE among the series, achieved pronounced photothermal tumor ablation without inducing systemic toxicity. Overall, this study proposes a molecular design strategy that synergistically modulates NIR absorption and photothermal conversion by enhancing the D-A push–pull effect. This strategy provides a design rationale for developing efficient, low-toxicity organic PTAs, and demonstrates potential applicability in low-power PTT modalities. Full article

Background and Aims: To evaluate whether the family history of diabetes mellitus (FHD⁺) is associated with markers of glucose homeostasis in healthy adults. Methods: Studies evaluating adults aged 18 to 60 years without a diagnosis of cardiometabolic disease, and reporting the influence of FHD⁺ (at least one first-degree relative) on fasting and 2 h postload glucose, and fasting insulin were included. The electronic database MEDLINE (via PubMed) was searched in February 2026 for studies published in English. Results are presented as mean differences with 95% confidence intervals, using random-effects models. Sensitivity analyses were performed considering study design, methodological quality, the definition of FHD⁺, and participants’ age and sex. Results: Twenty-six studies totaling 3122 individuals were included. Fasting glucose [3.48 (1.34–5.63) mg·dL⁻¹; – = 90%], 2 h postload glucose [4.18 (2.27–6.10) mg·dL⁻¹; I² = 38%], A1c [0.12 (0.04–0.19)%; – = 67%]; fasting insulin [1.72 (0.97–2.48) µU·mL⁻¹; – = 90%], and HOMA–IR [0.55 (0.42–0.69); – = 70%] were higher (p < 0.001) in individuals with an FHD⁺. Meta-regression analyses showed no significant associations between mean age or BMI and markers of glucose homeostasis. Findings remained robust across sensitivity and subgroup analyses, with reduced heterogeneity for some outcomes. Conclusions: The available evidence suggests that FHD⁺ may be associated with markers of impaired glucose homeostasis in healthy adults. However, these results should be interpreted with caution and confirmed in higher-quality prospective studies. Full article

Background/Objectives: Exposure to high and sustained levels of non-esterified fatty acids (NEFA) in the peripartal period is the main cause of fatty liver disease in dairy cows. Rumen-protected choline is often fed as part of the nutritional management of peripartal cows, with in vivo and in vitro data indicating positive effects of this nutrient on alleviating liver lipid accumulation. Although hepatic molecular mechanisms associated with choline supply have been studied using a target gene, protein, or metabolite approach, application of high-throughput technologies could vastly enhance fundamental knowledge on the functional role of choline. The main objective was to challenge isolated hepatocytes with a mixture of NEFA and determine proteome- and metabolome-wide effects in response to choline supply. Methods: Three healthy female calves (1 d old, 30–45 kg) were sacrificed to harvest hepatocytes. During a 12 h incubation, isolated hepatocytes were challenged without NEFA (control), 1.2 mM NEFA (c9-18:1, 18:2, 16:0, 18:0, and c9-16:1 at 43.5%, 4.9%, 31.9%, 14.4%, and 5.3% of total NEFA, respectively), or NEFA for 6 h followed by 10 μM choline chloride for another 6 h (NEFA + Chol). iTRAQ labeling-based protein profiling and GC/MS-based metabolomics profiling were used to determine changes in proteins and metabolites. Differentially abundant proteins for each group comparison were determined at a threshold of 1.4-fold change. Differences in metabolite profiles were assessed via pairwise comparisons. A subset of differentially abundant proteins was validated via qRT-PCR and Western blotting. Results: Compared with the control, there were 90 proteins and 22 metabolites in the NEFA group, and 83 proteins and 29 metabolites in the NEFA + Chol. Compared with NEFA, there were 49 proteins and 17 metabolites in the NEFA + Chol group. Greater abundance of hexokinase-1 (HK1), fructose-bisphosphate aldolase (ALDOA), mitochondrial pyruvate carrier 1 (MPC1), and increased concentrations of lactate with high NEFA treatment alone suggested greater glycolytic and TCA cycle activity. Accumulation of triacylglycerol in the NEFA group was associated with lipotoxicity and markers of inflammation, such as greater abundance of prostaglandin reductase 1 (PTGR1), serious cell autophagy processes, such as greater abundance of cell division cycle 42 (CDC42), and NFκB-related proteins. Choline supplementation reduced TAG partly due to greater VLDL secretion driven by greater abundance of diacylglycerol acyltransferase (DGAT1), perilipin 3 (PLIN3), and apolipoprotein C-III (APOC3). In addition, a greater abundance of carnitine O-palmitoyltransferase 1b (CPT1B) with choline suggested enhanced mitochondrial β-oxidation. Activation of the CDC42/JNK pathway and ROS/NFκB axis-related proteins, along with depressed PI3K/AKT/RAC-related proteins, indicated enhanced mitochondrial autophagy in response to NEFA. Conclusions: Overall, data confirmed published effects of choline on TAG accumulation, VLDL secretion, and fatty acid oxidation, while highlighting negative effects of NEFA on the respiratory electron transport chain, autophagy, and inflammatory processes. Full article

Ionization potentials and electron affinities provide the energetic basis for several conceptual density functional theory descriptors, but their use in donor–acceptor maps requires careful distinction between physically bound anions, weak or borderline electron-affinity cases, and formally computed diagnostic states. In this work, a periodic donor–acceptor descriptor map was constructed for main-group atoms from H to Kr using a $\Delta$SCF-DFT framework. Neutral atoms, monocations, and formally defined monoanionic states were evaluated to obtain ionization potentials, electron affinities, and global reactivity descriptors, including electronegativity, chemical hardness, chemical potential, electrophilicity, electrodonating power, and electroaccepting power. The production dataset was calculated at the $\omega$B97X-D4/def2-QZVPPD level and benchmarked against reference atomic data. This protocol reproduced ionization potentials with a mean absolute error of 0.134 eV and electron affinities with a mean absolute error of 0.116 eV for the reference EA set, including the weak calcium case. A functional and basis-set sensitivity analysis using $\omega$B97X-D4/def2-TZVPPD, PBE0/def2-QZVPPD, and PBE0/def2-TZVPPD showed that ionization potentials are comparatively robust, whereas electron affinities are strongly affected by the quality of the diffuse basis set. The normalized donor–acceptor map reproduces chemically intuitive periodic trends, with alkali metals occupying the strong-donor region and halogens defining the strong-acceptor region. The analysis explicitly separates core validation atoms from weak or borderline electron-affinity cases and diagnostic finite-basis anionic states, emphasizing that formally computed negative electron affinities for unbound anions should not be interpreted as physical bound states. The resulting nonrelativistic dataset provides a reproducible atomic descriptor reference for interpreting donor–acceptor behavior in atoms, clusters, superatoms, doped materials, and charge-transfer systems. Full article

Co- and Ni-doped mullite–spinel ceramics were synthesized via a sol–gel method followed by high-temperature sintering in order to investigate the influence of dopant type on the phase evolution, microstructure, and optical properties. X-ray diffraction analysis confirmed the formation of a multiphase system consisting of mullite and spinel phases, with a residual amorphous fraction, the amount of which decreases with increasing temperature. FTIR and Raman spectroscopy indicate progressive structural ordering of both spinel and aluminosilicate networks during thermal treatment, with differences in crystallization behavior between Co- and Ni-containing system. UV–Vis spectroscopy revealed characteristic absorption bands arising from d–d electronic transitions of Co²⁺ and Ni²⁺ ions in the ceramic matrix, reflecting differences in their local coordination environments and optical behavior. Colorimetric analysis showed that Co-doped samples exhibit intense blue coloration, whereas Ni-doped ceramics display greenish-blue hues. The temperature-dependent evolution of the L*, a*, and b* parameters correlate with structural changes. The results suggest that the type of additive influences the phase evolution and optical response in mullite–spinel ceramics, in agreement with structural and spectroscopic analyses. Full article

Organophosphate flame retardants (OPFRs) are widely used as flame-retardant additives in plastics, electronics, and building materials. However, growing evidence suggests these compounds may pose significant neurotoxic risks. This study evaluated phenotypic alterations, such as cell viability, reactive oxygen species generation, and acetylcholinesterase activity, induced by seven widely detected OPFRs in SH-SY5Y human neuroblastoma cells. Aromatic OPFRs such as triphenyl phosphate (TPhP), 2-ethylhexyldiphenyl phosphate (EHDPhP) and tricresyl phosphate (TCP) exhibited the strongest effects, including decreased cell viability, increased oxidative stress and AChE inhibition. Therefore, 3D brain organoid models were used to further explore the potential lipidomic alterations induced by aromatic OPFRs. Lipidomic analysis of brain organoids exposed to aromatic OPFRs (TPhP, EHDPhP and TCP) showed significant alterations across major lipid classes, especially glycerophospholipids, sphingolipids, and glycerolipids. The depletion of bis(monoacylglycerol)phosphate (BMP) species suggests perturbations in endolysosomal lipid homeostasis and membrane trafficking pathways. Increased levels of ether-linked lysophosphatidylcholine (LPC-O) species, together with altered phosphatidylethanolamine (PE) and phosphatidylserine (PS) species, indicate extensive membrane lipid remodeling and changes in cellular signaling. Furthermore, the accumulation of diacylglycerol (DG) and triacylglycerol (TG) species points to disturbances in lipid storage and metabolism. Overall, these findings indicate that aromatic OPFRs induce cytotoxicity, oxidative stress, and alteration of cholinergic function, and are associated with lipid dysregulation linked to neurotoxicity in brain organoids. Future research should explore chronic low-dose exposure and long-term neurological effects. Full article

Against the backdrop of rapid development in low-carbon building materials, geopolymer mortar has become a high-quality alternative to traditional cement-based materials due to its advantages of environmental friendliness, high strength, and excellent durability. However, its inherent brittleness and tendency to crack severely limit its widespread adoption and use in engineering. To mitigate the inherent brittleness of geopolymer mortar, this study developed a ternary binder system composed of metakaolin, slag, and fly ash. The effects of basalt fiber contents of 0%, 0.25%, 0.50%, 0.75%, 1.00%, and 1.25% by mass on the flowability, flexural strength, compressive strength, and deformation behavior of the geopolymer mortar were systematically investigated. The evolution of the displacement and strain fields during flexural and compressive loading was monitored in real time using two-dimensional digital image correlation (2D-DIC). The fiber-reinforcement mechanism was further examined by X-ray diffraction (XRD), scanning electron microscopy (SEM), and Fourier transform infrared spectroscopy (FTIR). The results show that basalt fiber reduces mortar flowability, and the reduction becomes more pronounced with increasing fiber content. The flexural strength first increased and then decreased with increasing fiber content; at 0.50% fiber content, the 28-day flexural strength reached 12.6 MPa, which was 8.2% higher than that of the fiber-free control. The compressive strength increased only slightly at a low fiber content of 0.25% and then decreased when the fiber content exceeded 0.50%. The 2D-DIC results indicate that a moderate fiber content (0.50–0.75%) markedly increased the ultimate displacement, delayed crack propagation, and enhanced the post-cracking deformation capacity. Microstructural observations revealed that an appropriate fiber content promoted good interfacial bonding with the matrix and enabled fiber bridging and crack resistance. In contrast, excessive fiber addition caused agglomeration-induced micropores and microcracks, thereby degrading mechanical properties. Overall, the recommended basalt fiber content is 0.25–0.50%. These findings provide a theoretical and experimental basis for optimizing high-performance, low-carbon geopolymer mortar for engineering applications. Full article

Removing mercury (Hg²⁺) from aqueous environments remains a major environmental challenge due to its high toxicity and bioaccumulation. Graphene quantum dots (GQDs) are adsorbents that show promise in removing these contaminants, but their yield is low in their pristine form. This study investigates the effect of phosphorus (P) doping on vacancy-containing GQDs to enhance Hg²⁺ absorption using density functional theory (DFT) calculations. These were performed at the M06-2X/def2-TZVP level of theory to optimize the structures of GQDs, 1P-GQDs, and 2P-GQDs to evaluate adsorption energies, frontier molecular orbitals, and dipole moments. The results show that GQDs with vacancy have an adsorption energy of −65.21 kcal mol⁻¹, which increases to −104.54 kcal mol⁻¹ for 1P-GQDs, indicating the strongest Hg²⁺ binding. However, 2P-GQD shows a lower value of −73.47 kcal mol⁻¹, suggesting lower efficiency due to electronic competition between dopants. Dipole moments increase from 0.8192 D (GQD) to 4.6729 D (1P-GQD) and 5.7557 D (2P-GQD), confirming strong polarization induced by P incorporation. The HOMO-LUMO gap decreases from 2.204 eV to 1.937 eV after single doping. At the same time, after Hg²⁺ adsorption, the values increase to 5.153 eV (GQD), 3.462 eV (1P-GQD), and 2.068 eV (2P-GQD), indicating configuration-dependent electronic stabilization. PDOS analysis confirms weak cation-π interaction in GQD and strong orbital hybridization in 1P-GQD, consistent with a coordination-type bond. Doping a single phosphate atom optimizes the electronic structure of GQDs with a vacancy site, thereby improving charge transfer and adsorption strength through electronic balance. Full article

Background: Cytarabine (Ara-C) remains the cornerstone of remission-induction and consolidation chemotherapy for acute myeloid leukemia (AML) and related hematological malignancies. Despite more than six decades of clinical use, its multi-organ toxicity continues to be managed almost exclusively through dose attenuation and supportive care, with no approved upstream pharmacological prevention strategy available. Objectives: This scoping review aimed to systematically map the breadth and nature of pharmacological agents tested in vivo for their capacity to mitigate cytarabine-induced multi-organ toxicity, to characterize their mechanisms of action and organ targets, and to identify evidence gaps and agents with translational potential. Methods: The review was designed and reported in accordance with the PRISMA-ScR checklist. A structured electronic search was conducted across PubMed/MEDLINE, Scopus, Cochrane Library and Embase, and Web of Science from database inception to 15 July 2025. Eligible studies were restricted to full-text, peer-reviewed, English-language research involving in vivo mammalian models administered cytarabine as the principal toxin, with at least one pharmacological co-intervention and at least one quantitative or histopathological organ-injury outcome. Results: From 5701 retrieved records, 36 eligible in vivo mammalian studies (spanning 1964–2024) were identified. Included studies addressed neurotoxicity (n = 6), gastrointestinal mucositis (n = 9), ocular toxicity (n = 3), hepatotoxicity (n = 3), bone marrow suppression (n = 4), chemotherapy-induced alopecia (n = 5), and reproductive and developmental toxicity (n = 4). Five recurring mechanistic strategies were identified across the heterogeneous agents tested: redox buffering (N-acetylcysteine, α-lipoic acid, rutin, swertiamarin, α-tocopherol), mitochondrial preservation (betanin, thymoquinone, vitamin D, sodium zinc dihydrolipoylhistidinate [DHLHZn]), tissue-microenvironment reprogramming (apraglutide, BADGE, plerixafor, short-chain fatty acids, β-glucan), molecular antagonism (deoxycytidine, dCMP), and immunomodulation (lienal peptide, IL-1β, AHCC). Conclusions: This scoping review provides the first systematic cartography of pharmacological mitigation strategies for cytarabine-induced multi-organ toxicity. Five mechanistic pathways converge across eight organ systems, with apraglutide and N-acetylcysteine representing the most clinically translatable candidates. Plerixafor and PPARγ blockade by BADGE constitute high-priority candidates for bone marrow niche protection, while the deoxycytidine antagonism principle warrants formal pharmacokinetic evaluation. The complete absence of cardiotoxicity mitigation data defines the most critical gap for future research. Full article

Background/Objectives: Type 2 diabetes (T2D) remission can be defined as a return to a HbA1c < 6.5% (<48 mmol/mol) sustained without ongoing treatment for at least 3 months. Prevalence estimates and factors associated remain unknown for LMIC and resource-limited settings. Methods: We conducted a retrospective observational analysis of electronic medical records from 8463 adults who received multidisciplinary care at Mexico’s primary care specialized units (UNEMES-EC) between 2015 and 2019 and who were referred for inadequate metabolic control. Remission was defined per 2021 ADA criteria as HbA1c <6.5% sustained for ≥3 months without glucose-lowering medications. After estimating the prevalence of T2D remission, logistic regression models were used to evaluate its sociodemographic and clinical predictors, with particular attention to weight change and baseline adiposity interactions. Results: RT2D prevalence was 0.87% (95% CI: 0.68–1.10) over a median 393-day follow-up. Weight loss ≥10% (adjusted OR 2.75; 95% CI: 1.21-6.27) and systolic blood pressure (tertile 3 vs tertile 1: OR 2.49; 95% CI: 1.17–5.26) were positively associated with RT2D, while elevated baseline HbA1c (tertile 3 vs. tertile 1: OR 0.09; 95% CI: 0.02–0.33), triglyceride levels (tertile 3 vs. tertile 1: OR 0.49; 95% CI: 0.24–0.98) and intensive pharmacotherapy were inversely associated with RT2D. No associations with HDL and total cholesterol were found. Age, sex, educational attainment, and income demonstrated no independent associations with remission. Among lifestyle-treated patients achieving ≥5% weight loss, remission prevalence reached approximately 11%. No significant interaction between baseline BMI and weight change was detected (p = 0.60). Conclusions: This first large-scale Mexican study establishes RT2D as an achievable endpoint in patients with poor baseline metabolic control. The findings suggest that remission could be achieved with equity-focused, weight-centered interventions even in resource-constrained health systems and populations. Full article

Lightweight polymer composites with effective electromagnetic interference (EMI) shielding are of increasing interest for advanced electronic and aerospace applications; however, conventional glass fiber-reinforced polymers (GFRPs) exhibit inherently low electrical conductivity, limiting their shielding performance. In this study, a hierarchical hybrid conductive architecture was developed by integrating graphene-coated multiaxial glass fiber fabrics with carbon black (CB)-reinforced epoxy matrices to enhance EMI shielding behavior in the X-band (8–12 GHz). Graphene coatings were deposited onto glass fibers via a surfactant-assisted ultrasonic dispersion method, while carbon black (0–1 wt.%) was incorporated into the epoxy matrix using ultrasonication-assisted mixing. Multilayer composites were fabricated using a vacuum bagging process. X-ray diffraction analysis revealed that the composites retained a predominantly amorphous epoxy/glass fiber matrix while exhibiting broad carbon-related diffraction features associated with disordered graphitic domains. Electrical conductivity measurements indicated that all composites remained in the insulating regime (~10⁻⁹ S/m), suggesting that a fully interconnected conductive network was not established within the investigated filler range. Despite the absence of a continuous conductive network, measurable EMI shielding performance was achieved. The composite containing 0.25 wt.% CB exhibited the highest shielding effectiveness, reaching approximately 12 dB at ~11.2 GHz. Analysis of the shielding contributions showed that absorption contributions (SEA) were consistently higher than reflection contributions (SER) across the studied frequency range. Morphological observations revealed that well-dispersed CB at low loading facilitated the formation of localized conductive domains that may contribute to tunneling-assisted polarization and interfacial charge accumulation. At higher CB contents, particle agglomeration reduced dispersion quality and limited effective pathway formation, while dynamic mechanical analysis indicated enhanced stiffness at low CB loading. FTIR results confirmed the absence of new chemical bonding, indicating that CB acts as a physically dispersed conductive filler. Overall, the results show that effective EMI shielding can be achieved in electrically insulating composites through the combined effect of hierarchical structural design and localized conductive features. This approach provides a practical pathway for developing lightweight EMI shielding materials with controlled filler loading and preserved structural integrity for aerospace and electronic applications. Full article