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Search Results (469)

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Keywords = 1450-nm diode laser

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17 pages, 1738 KiB  
Article
Evaluation of Optimal Visible Wavelengths for Free-Space Optical Communications
by Modar Dayoub and Hussein Taha
Telecom 2025, 6(3), 57; https://doi.org/10.3390/telecom6030057 - 4 Aug 2025
Viewed by 54
Abstract
Free-space optical (FSO) communications have emerged as a promising complement to conventional radio-frequency (RF) systems due to their high bandwidth, low interference, and license-free spectrum. Visible-light FSO communication, using laser diodes or LEDs, offers potential for short-range data links, but performance is highly [...] Read more.
Free-space optical (FSO) communications have emerged as a promising complement to conventional radio-frequency (RF) systems due to their high bandwidth, low interference, and license-free spectrum. Visible-light FSO communication, using laser diodes or LEDs, offers potential for short-range data links, but performance is highly wavelength-dependent under varying atmospheric conditions. This study presents an experimental evaluation of three visible laser diodes at 650 nm (red), 532 nm (green), and 405 nm (violet), focusing on their optical output power, quantum efficiency, and modulation behavior across a range of driving currents and frequencies. A custom laboratory testbed was developed using an Atmega328p microcontroller and a Visual Basic control interface, allowing precise control of current and modulation frequency. A silicon photovoltaic cell was employed as the optical receiver and energy harvester. The results demonstrate that the 650 nm red laser consistently delivers the highest quantum efficiency and optical output, with stable performance across electrical and modulation parameters. These findings support the selection of 650 nm as the most energy-efficient and versatile wavelength for short-range, cost-effective visible-light FSO communication. This work provides experimentally grounded insights to guide wavelength selection in the development of energy-efficient optical wireless systems. Full article
(This article belongs to the Special Issue Optical Communication and Networking)
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9 pages, 1131 KiB  
Article
The Impact of Low-Level Laser Irradiation on the Activity of Alpha-Amylase
by Mustafa Salih Al Musawi
Photonics 2025, 12(8), 774; https://doi.org/10.3390/photonics12080774 - 31 Jul 2025
Viewed by 193
Abstract
Background: Clinical diagnostics, food industries, and biotechnological processes typically use an enzyme called alpha-amylase to metabolize carbohydrates. Objective: The aim of this study is to investigate how low-level laser irradiation (LLLI) affects alpha-amylase activity towards determining the usability of LLLI in non-invasive [...] Read more.
Background: Clinical diagnostics, food industries, and biotechnological processes typically use an enzyme called alpha-amylase to metabolize carbohydrates. Objective: The aim of this study is to investigate how low-level laser irradiation (LLLI) affects alpha-amylase activity towards determining the usability of LLLI in non-invasive enzymatic modulation. Methods: Enzyme solutions were irradiated at 10, 20, 30, and 40 J/cm2 utilizing 589 nm and 532 nm diode-pumped solid-state lasers. The iodine–starch colorimetric method was used to quantify post-irradiation enzymatic activity, with inverse correlations found between absorbance and activity levels. Modulation was determined by the wavelength and dosage. Results: Enzymatic activity significantly improved when utilizing 589 nm irradiation at lower doses, maximizing at 120% at 20 J/cm2 (p < 0.01). Neutral or inhibitory effects were revealed when higher doses were applied. Enzymatic activity showed progressive inhibition when 532 nm irradiation was applied, declining to 75% at 40 J/cm2 (p < 0.01). Conclusions: These outcomes indicate that conformational flexibility and catalytic efficiency occur when applying lower-energy photons at 589 nm, whilst oxidative stress and impaired enzymatic function are induced by higher-energy photons at 532 nm. This is consistent with the biphasic dose–response characteristic of photobiomodulation. Full article
(This article belongs to the Special Issue Advanced Technologies in Biophotonics and Medical Physics)
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14 pages, 6123 KiB  
Article
Effects of Near-Infrared Diode Laser Irradiation on Pain Relief and Neuropeptide Markers During Experimental Tooth Movement in the Periodontal Ligament Tissues of Rats: A Pilot Study
by Kanako Okazaki, Ayaka Nakatani, Ryo Kunimatsu, Isamu Kado, Shuzo Sakata, Hirotaka Kiridoshi and Kotaro Tanimoto
Int. J. Mol. Sci. 2025, 26(15), 7404; https://doi.org/10.3390/ijms26157404 - 31 Jul 2025
Viewed by 169
Abstract
Pain following orthodontic treatment is the chief complaint of patients undergoing this form of treatment. Although the use of diode lasers has been suggested for pain reduction, the mechanism of laser-induced analgesic effects remains unclear. Neuropeptides, such as substance P (SP) and calcitonin [...] Read more.
Pain following orthodontic treatment is the chief complaint of patients undergoing this form of treatment. Although the use of diode lasers has been suggested for pain reduction, the mechanism of laser-induced analgesic effects remains unclear. Neuropeptides, such as substance P (SP) and calcitonin gene-related peptide (CGRP), contribute to the transmission and maintenance of inflammatory pain. Heat shock protein (HSP) 70 plays a protective role against various stresses, including orthodontic forces. This study aimed to examine the effects of diode laser irradiation on neuropeptides and HSP 70 expression in periodontal tissues induced by experimental tooth movement (ETM). For inducing ETM for 24 h, 50 g of orthodontic force was applied using a nickel–titanium closed-coil spring to the upper left first molar and the incisors of 20 male Sprague Dawley rats (7 weeks old). The right side without ETM treatment was considered the untreated control group. In 10 rats, diode laser irradiation was performed on the buccal and palatal sides of the first molar for 90 s with a total energy of 100.8 J/cm2. A near-infrared (NIR) laser with a 808 nm wavelength, 7 W peak power, 560 W average power, and 20 ms pulse width was used for the experiment. We measured the number of facial groomings and vacuous chewing movements (VCMs) in the ETM and ETM + laser groups. Immunohistochemical staining of the periodontal tissue with SP, CGRP, and HSP 70 was performed. The number of facial grooming and VCM periods significantly decreased in the ETM + laser group compared to the ETM group. Moreover, the ETM + laser group demonstrated significant suppression of SP, CGRP, and HSP 70 expression. These results suggest that the diode laser demonstrated analgesic effects on ETM-induced pain by inhibiting SP and CGRP expression, and decreased HSP 70 expression shows alleviation of cell damage. Thus, although further validation is warranted for human applications, an NIR diode laser can be used for reducing pain and neuropeptide markers during orthodontic tooth movement. Full article
(This article belongs to the Special Issue Advances in Photobiomodulation Therapy)
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10 pages, 2289 KiB  
Communication
Raman Gas Analysis with External Power Build-Up Cavity of Line-Narrowed 407-nm Laser Diode
by Zhongyi Yao, Xinbing Wang and Duluo Zuo
Sensors 2025, 25(15), 4600; https://doi.org/10.3390/s25154600 - 25 Jul 2025
Viewed by 212
Abstract
An external power build-up cavity of a line-narrowed 407-nm laser diode for Raman gas analysis was demonstrated to possess good gas detection capabilities. By employing an ordinary laser diode without anti-reflection coating or and a bandpass interference filter in an external cavity resonance, [...] Read more.
An external power build-up cavity of a line-narrowed 407-nm laser diode for Raman gas analysis was demonstrated to possess good gas detection capabilities. By employing an ordinary laser diode without anti-reflection coating or and a bandpass interference filter in an external cavity resonance, the laser linewidth was narrowed by resonant optical feedback, and tens of watts of external cavity power were built up. The coupling mechanism between the semiconductor laser and the external cavity are discussed, as well as the noise background in the experimental results. The Raman spectrum of ambient air was analyzed, achieving a methane detection limit of 1 ppm. Full article
(This article belongs to the Special Issue Spectroscopy Gas Sensing and Applications)
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16 pages, 4472 KiB  
Article
Effect of Low-Level Laser Therapy on Periodontal Host Cells and a Seven-Species Periodontitis Model Biofilm
by Selma Dervisbegovic, Susanne Bloch, Vera Maierhofer, Christian Behm, Xiaohui Rausch-Fan, Andreas Moritz, Christina Schäffer and Oleh Andrukhov
Int. J. Mol. Sci. 2025, 26(14), 6803; https://doi.org/10.3390/ijms26146803 - 16 Jul 2025
Viewed by 328
Abstract
Low-level laser therapy (LLLT) is gaining attention as an effective adjunct to non-surgical periodontal treatment. This study evaluates the potential of LLLT to reduce bacterial load in a clinically relevant in vitro subgingival biofilm model and its impact on the inflammatory response. A [...] Read more.
Low-level laser therapy (LLLT) is gaining attention as an effective adjunct to non-surgical periodontal treatment. This study evaluates the potential of LLLT to reduce bacterial load in a clinically relevant in vitro subgingival biofilm model and its impact on the inflammatory response. A subgingival biofilm model consisting of seven bacterial species was established. Primary human gingival fibroblasts (GFs) and periodontal ligament cells (PDLs) were cultured. Both biofilms and host cells were treated with the DenLase Diode Laser (980 nm) under various clinically relevant settings. The composition and structure of the seven-species biofilms were evaluated using quantitative PCR and fluorescence microscopy, respectively. The inflammatory response in host cells was analyzed by measuring the gene and protein expression levels of various inflammatory mediators. Laser treatment at power outputs ranging from 0.3 to 2 W had no significant effect on biofilm composition or architecture. LLLT, particularly at higher power settings, reduced the viability in both GFs and PDLs up to 70%. Gene expression levels of inflammatory mediators were only minimally influenced by laser treatment. However, LLLT significantly decreased the secretion of all examined cytokines. These findings suggest that LLLT with a 980 nm diode laser, under clinically relevant conditions, exerts anti-inflammatory rather than antimicrobial effects. Full article
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14 pages, 1172 KiB  
Article
Laser-Mediated Hemostasis for Older Patients Receiving Routine Dental Treatment
by Suwat Tanya, Saengsome Prajaneh, Piyachat Patcharanuchat and Sajee Sattayut
Dent. J. 2025, 13(7), 315; https://doi.org/10.3390/dj13070315 - 11 Jul 2025
Viewed by 312
Abstract
Background/Objective: Laser therapy has gained attention in dental practice to minimize bleeding and enhance blood clot formation. This study aimed to explore the utilization and to compare the clinical efficacy of laser-mediated hemostasis for older patients receiving routine dental treatment. Methods: A prospective [...] Read more.
Background/Objective: Laser therapy has gained attention in dental practice to minimize bleeding and enhance blood clot formation. This study aimed to explore the utilization and to compare the clinical efficacy of laser-mediated hemostasis for older patients receiving routine dental treatment. Methods: A prospective observational study was conducted across research networks between October 2023 and August 2024, involving 60 patients aged 50 years and older (average = 63.35 years) at risk of postoperative bleeding following dental treatments. Additionally, laser therapy for hemostasis was selected and provided among calibrated operators. A single researcher performed data collection. Before statistical analysis, data verification and clinical assessment were conducted by the operators and researcher. A clinical cut-off for hemostasis was set at 5 min. Two diode laser machines were used namely, an 810 nm and dual wavelengths of 635 nm and 980 nm. Results: There were 94 extraction sockets, 28 procedures of scaling and root planing and 18 procedures of minor oral surgery. Combining laser ablating sulcular fiber and photobiomodulation initiating blood clot formation was a preferable hemostatic technique for extraction socket, while photobiomodulation alone was a preferred technique for soft tissue hemostasis (p < 0.001). All operators confirmed that 97.86 percent of bleeding events achieved more rapid hemostasis. 61.43 percent of bleeding events clinically achieved hemostasis within 5 min by using laser-mediated hemostasis alone (p = 0.092). Full recovery of the extraction socket was significantly observed during the 2- to 4-week follow-up period (p = 0.005). No clinical complications were reported. Conclusions: Laser-mediated hemostasis effectively reduced hemostatic duration, prevented postoperative bleeding and promoted wound healing in older patients undergoing routine dental treatment. Full article
(This article belongs to the Special Issue Laser Dentistry: The Current Status and Developments)
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16 pages, 3764 KiB  
Article
Luminescence of Carbon Dots Induced by MeV Protons
by Mariapompea Cutroneo, Vladimir Havranek, Vaclav Holy, Petr Malinsky, Petr Slepicka, Selena Cutroneo and Lorenzo Torrisi
Chemosensors 2025, 13(7), 245; https://doi.org/10.3390/chemosensors13070245 - 9 Jul 2025
Viewed by 361
Abstract
In this study, we describe the preparation of carbon dots (CDs) from natural charcoal by laser ablation in a liquid. A continuum wave (CW) laser diode operating at a wavelength of 450 nm, hitting a solid carbon target placed into a biocompatible liquid, [...] Read more.
In this study, we describe the preparation of carbon dots (CDs) from natural charcoal by laser ablation in a liquid. A continuum wave (CW) laser diode operating at a wavelength of 450 nm, hitting a solid carbon target placed into a biocompatible liquid, constituted of a phosphate-buffered saline (PBS) solution and distilled water, was used for the generation of the CDs suspension. Exploring the practical applications of carbon dots, it was observed that the luminescence of the produced CDs can be used as bioimaging in living organisms, environmental monitoring, chemical analysis, targeted drug delivery, disease diagnosis, therapy, and others. The CDs’ luminescence can be induced by UV irradiation and, as demonstrated in this study, by energetic MeV proton beams. The fluorescence was revealed mainly at 480 nm when UV illuminated the CDs, and also in the region at 514–642 nm when the CDs were irradiated by energetic proton ions. Atomic force microscopy (AFM) of the CD films revealed their spherical shape with a size of about 10 nm. The significance of the manuscript lies in the use of CDs produced by laser ablation exhibiting luminescence under irradiation of an energetic proton beam. Full article
(This article belongs to the Section Materials for Chemical Sensing)
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17 pages, 1027 KiB  
Review
Photon Detector Technology for Laser Ranging: A Review of Recent Developments
by Zhihui Li, Xin Jin, Changfu Yuan and Kai Wang
Coatings 2025, 15(7), 798; https://doi.org/10.3390/coatings15070798 - 8 Jul 2025
Viewed by 582
Abstract
Laser ranging technology holds a key position in the military, aerospace, and industrial fields due to its high precision and non-contact measurement characteristics. As a core component, the performance of the photon detector directly determines the ranging accuracy and range. This paper systematically [...] Read more.
Laser ranging technology holds a key position in the military, aerospace, and industrial fields due to its high precision and non-contact measurement characteristics. As a core component, the performance of the photon detector directly determines the ranging accuracy and range. This paper systematically reviews the technological development of photonic detectors for laser ranging, with a focus on analyzing the working principles and performance differences of traditional photodiodes [PN (P-N junction photodiode), PIN (P-intrinsic-N photodiode), and APD (avalanche photodiode)] (such as the high-frequency response characteristics of PIN and the internal gain mechanism of APD), as well as their applications in short- and medium-range scenarios. Additionally, this paper discusses the unique advantages of special structures such as transmitting junction-type and Schottky-type detectors in applications like ultraviolet light detection. This article focuses on photon counting technology, reviewing the technological evolution of photomultiplier tubes (PMTs), single-photon avalanche diodes (SPADs), and superconducting nanowire single-photon detectors (SNSPDs). PMT achieves single-photon detection based on the external photoelectric effect but is limited by volume and anti-interference capability. SPAD achieves sub-decimeter accuracy in 100 km lidars through Geiger mode avalanche doubling, but it faces challenges in dark counting and temperature control. SNSPD, relying on the characteristics of superconducting materials, achieves a detection efficiency of 95% and a dark count rate of less than 1 cps in the 1550 nm band. It has been successfully applied in cutting-edge fields such as 3000 km satellite ranging (with an accuracy of 8 mm) and has broken through the near-infrared bottleneck. This study compares the differences among various detectors in core indicators such as ranging error and spectral response, and looks forward to the future technical paths aimed at improving the resolution of photon numbers and expanding the full-spectrum detection capabilities. It points out that the new generation of detectors represented by SNSPD, through material and process innovations, is promoting laser ranging to leap towards longer distances, higher precision, and wider spectral bands. It has significant application potential in fields such as space debris monitoring. Full article
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18 pages, 2702 KiB  
Article
Real-Time Depth Monitoring of Air-Film Cooling Holes in Turbine Blades via Coherent Imaging During Femtosecond Laser Machining
by Yi Yu, Ruijia Liu, Chenyu Xiao and Ping Xu
Photonics 2025, 12(7), 668; https://doi.org/10.3390/photonics12070668 - 2 Jul 2025
Viewed by 369
Abstract
Given the exceptional capabilities of femtosecond laser processing in achieving high-precision ablation for air-film cooling hole fabrication on turbine blades, it is imperative to develop an advanced monitoring methodology that enables real-time feedback control to automatically terminate the laser upon complete penetration detection, [...] Read more.
Given the exceptional capabilities of femtosecond laser processing in achieving high-precision ablation for air-film cooling hole fabrication on turbine blades, it is imperative to develop an advanced monitoring methodology that enables real-time feedback control to automatically terminate the laser upon complete penetration detection, thereby effectively preventing backside damage. To tackle this issue, a spectrum-domain coherent imaging technique has been developed. This innovative approach adapts the fundamental principle of fiber-based Michelson interferometry by integrating the air-film hole into a sample arm configuration. A broadband super-luminescent diode with a 830 nm central wavelength and a 26 nm spectral bandwidth serves as the coherence-optimized illumination source. An optimal normalized reflectivity of 0.2 is established to maintain stable interference fringe visibility throughout the drilling process. The system achieves a depth resolution of 11.7 μm through Fourier transform analysis of dynamic interference patterns. With customized optical path design specifically engineered for through-hole-drilling applications, the technique demonstrates exceptional sensitivity, maintaining detection capability even under ultralow reflectivity conditions (0.001%) at the hole bottom. Plasma generation during laser processing is investigated, with plasma density measurements providing optical thickness data for real-time compensation of depth measurement deviations. The demonstrated system represents an advancement in non-destructive in-process monitoring for high-precision laser machining applications. Full article
(This article belongs to the Special Issue Advances in Laser Measurement)
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9 pages, 1553 KiB  
Communication
Orthogonally Polarized Pr:LLF Red Laser at 698 nm with Tunable Power Ratio
by Haotian Huang, Menghan Jia, Yuzhao Li, Jing Xia, Nguyentuan Anh and Yanfei Lü
Photonics 2025, 12(7), 666; https://doi.org/10.3390/photonics12070666 - 1 Jul 2025
Viewed by 175
Abstract
A continuous-wave (CW) orthogonally polarized single-wavelength red laser (OPSRL) at 698 nm with a tunable power ratio within a wide range between the two polarized components was demonstrated using two Pr3+:LiLuF4 (Pr:LLF) crystals for the first time. Through control of [...] Read more.
A continuous-wave (CW) orthogonally polarized single-wavelength red laser (OPSRL) at 698 nm with a tunable power ratio within a wide range between the two polarized components was demonstrated using two Pr3+:LiLuF4 (Pr:LLF) crystals for the first time. Through control of the waist location of the pump beam in the active media, the output power ratio of the two polarized components of the OPSRL could be adjusted. Under pumping by a 20 W, 444 nm InGaN laser diode (LD), a maximum total output power of 4.12 W was achieved with equal powers for both polarized components, corresponding to an optical conversion efficiency of 23.8% relative to the absorbed pump power. Moreover, by a type-II critical phase-matched (CPM) BBO crystal, a CW ultraviolet (UV) second-harmonic generation (SHG) at 349 nm was also obtained with a maximum output power of 723 mW. OPSRLs can penetrate deep tissues and demonstrate polarization-controlled interactions, and are used in bio-sensing and industrial cutting with minimal thermal distortion, etc. The dual-polarized capability of OPSRLs also supports multi-channel imaging and high-speed interferometry. Full article
(This article belongs to the Section Lasers, Light Sources and Sensors)
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16 pages, 3766 KiB  
Article
The Efficacy of Erbium-Ion, Diode, and CO2 Lasers in Debonding Attachments Used During Overlay Orthodontic Treatment and the Risk of Hard Tooth Tissue Damage Compared to Traditional Methods—An In Vitro Study
by Alina Florczak-Matyjek, Anna Nikodem, Julia Kensy, Jacek Matys and Kinga Grzech-Leśniak
Photonics 2025, 12(6), 621; https://doi.org/10.3390/photonics12060621 - 18 Jun 2025
Viewed by 401
Abstract
Objective: This in vitro study evaluated the effectiveness of three laser systems—diode, CO2, and Er:YAG—for debonding composite attachments used in aligner orthodontic therapy. Materials and Methods: Fifty extracted human premolars with composite attachments were divided into five groups (n = [...] Read more.
Objective: This in vitro study evaluated the effectiveness of three laser systems—diode, CO2, and Er:YAG—for debonding composite attachments used in aligner orthodontic therapy. Materials and Methods: Fifty extracted human premolars with composite attachments were divided into five groups (n = 10): control, RT (rotary tools), diode laser (980 nm, irradiance was 4811 W/cm2), CO2 laser (10.6 µm, irradiance 1531 W/cm2), and Er:YAG laser (2940 nm, irradiance 471.7 W/cm2). Shear bond strength (SBS) testing measured debonding forces. Enamel surface changes were evaluated using micro-CT, optical profilometry, and stereomicroscopy. The Adhesive Remnant Index (ARI) assessed residual bonding material. Results: Laser treatment increased enamel roughness (p < 0.05). Er:YAG laser caused the highest roughness (Sa = 2.03 µm) and up to 0.17 mm enamel loss but left minimal adhesive remnants and no fractures. Diode laser preserved surface smoothness with moderate bond weakening. CO2 laser had intermediate effects. RT showed the highest SBS but resulted in greater enamel alteration. SBS was significantly reduced in the laser groups, lowest for Er:YAG (81.7 ± 45.5 MPa vs. control 196.2 ± 75.3 MPa). ARI indicated better adhesive removal in the laser-treated groups, with Er:YAG showing the highest percentage of clean enamel surfaces (67% vs. 25%). Conclusions: Er:YAG demonstrated the best balance between effective debonding and enamel preservation. Diode and CO2 lasers also offer viable alternatives to rotary tools. Further clinical studies are recommended. Full article
(This article belongs to the Special Issue Photonics: 10th Anniversary)
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11 pages, 3520 KiB  
Communication
Diode-End-Pumped Continuous-Wave Tunable Nd3+:LiYF4 Laser Operating on the 4F3/24I13/2 Transition
by Chu Chu, Shuang Wang, Xinhua Fu and Zhenhua Du
Photonics 2025, 12(6), 613; https://doi.org/10.3390/photonics12060613 - 14 Jun 2025
Viewed by 313
Abstract
A laser diode (LD) end-pumped continuous-wave (CW) tunable Nd3+:LiYF4 (Nd:YLF) laser operating on the 4F3/24I13/2 transition was performed. Four single-wavelength (SW) lasing at 1321, 1314, 1371, and 1364 nm in the π-polarized direction and [...] Read more.
A laser diode (LD) end-pumped continuous-wave (CW) tunable Nd3+:LiYF4 (Nd:YLF) laser operating on the 4F3/24I13/2 transition was performed. Four single-wavelength (SW) lasing at 1321, 1314, 1371, and 1364 nm in the π-polarized direction and three SW lasing at 1314, 1326, and 1371 nm in the σ-polarized direction were achieved using a tuning prism. At 20 W pump power, the σ-polarized 1314 nm emission generated 7.3 W power output with 39.4% slope efficiency. Further, the three-pair of switchable π-polarized dual-wavelengths (DWs) at 1321/1314 nm, 1371/1364 nm, and 1321/1364 nm and the two-pair of switchable σ-polarized DWs at 1314/1326 nm and 1314/1371 nm were also realized by rotating an intracavity birefringence filter (BF). In addition, by employing dual intracavity BFs, the balanced DW output power was attained, achieving 6.4 W total maximum output at 1314/1321 nm in the π-polarized direction. Full article
(This article belongs to the Section Lasers, Light Sources and Sensors)
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11 pages, 661 KiB  
Article
Histological Evaluation of Oral Soft Tissue Biopsy by Dual-Wavelength Diode Laser: An Ex Vivo Study
by Daniele Pergolini, Alessandro Del Vecchio, Mohamed Mohsen, Veronica Cerullo, Cinzia Angileri, Eduardo Troiani, Paolo Visca, Barbara Antoniani, Umberto Romeo and Gaspare Palaia
Dent. J. 2025, 13(6), 265; https://doi.org/10.3390/dj13060265 - 13 Jun 2025
Viewed by 364
Abstract
Background: Diode lasers are valuable in oral surgery due to their excellent hemostasis, minimum post-operative pain, and minimally invasive procedures. A dual-wavelength diode laser in dentistry combines two distinct wavelengths, typically 450 nm and 808 nm, to provide a versatile approach to soft [...] Read more.
Background: Diode lasers are valuable in oral surgery due to their excellent hemostasis, minimum post-operative pain, and minimally invasive procedures. A dual-wavelength diode laser in dentistry combines two distinct wavelengths, typically 450 nm and 808 nm, to provide a versatile approach to soft tissue procedures. This ex vivo study investigated the quantity of thermal effects of a dual-wavelength diode laser on porcine lingual mucosa to determine the optimal laser parameters for oral soft tissue biopsies and to improve the reliability of histological evaluation. The presence of thermal damage in the prelesional margins may compromise the diagnostic accuracy, particularly in cases of suspected malignancy. Methods: Thirty-six porcine lingual mucosa samples were excised using a diode laser (Wiser 3, Doctor Smile) in continuous wave (CW) and pulsed wave (PW) modes at average powers of 2, 3, and 4 W. The samples, preserved in 5% buffered formalin, underwent histological evaluation to measure epithelial and connective tissue damage. Results: The study demonstrated variable thermal effects depending on the laser mode and power settings. Minimal epithelial damage (0.62 mm) was observed at 2 W CW, while maximum damage (3.12 mm) occurred at 4 W pulsed wave (PW). Connective tissue exhibited slightly greater damage than epithelial tissue, with minimal damage (0.53 mm) at 4 W CW and maximum damage (3.19 mm) at 4 W pulsed wave (PW). Statistical analyses were performed using t-tests and ANOVA and revealed significant differences in tissue damage between certain groups, highlighting the impact of laser parameters on thermal effects. Conclusions: The dual-wavelength diode laser seems to have good surgical properties and is suitable for managing complex clinical cases. Although the low power average showed minimal thermal damage, for the importance of the diagnosis of suspected lesions of malignancy, a 2 mm prelesional margin should be maintained. Full article
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15 pages, 2347 KiB  
Article
In Vitro Evaluation of Candida spp. and Staphylococcus aureus Sensitivity to 450 nm Diode Laser-Mediated Antimicrobial Photodynamic Therapy with Curcumin and Riboflavin
by Marcin Tkaczyk, Anna Mertas, Anna Kuśka-Kiełbratowska, Jakub Fiegler-Rudol, Elżbieta Bobela, Maria Cisowska, Tadeusz Morawiec, Dariusz Skaba and Rafał Wiench
Int. J. Mol. Sci. 2025, 26(12), 5645; https://doi.org/10.3390/ijms26125645 - 12 Jun 2025
Viewed by 710
Abstract
Oral candidiasis, commonly caused by Candida (C.) albicans and other non-albicans Candida species, increases resistance to conventional antifungal therapies. This study aimed to evaluate the in vitro efficacy of antimicrobial photodynamic therapy (aPDT) using a 450 nm diode laser in combination [...] Read more.
Oral candidiasis, commonly caused by Candida (C.) albicans and other non-albicans Candida species, increases resistance to conventional antifungal therapies. This study aimed to evaluate the in vitro efficacy of antimicrobial photodynamic therapy (aPDT) using a 450 nm diode laser in combination with curcumin and riboflavin against Candida spp. and Staphylococcus (S.) aureus. Reference strains of C. albicans, C. glabrata, C. krusei, and S. aureus were exposed to aPDT under varying incubation times and laser parameters, then viable microorganism cells (CFU) counts were assessed the microbial reduction, and statistical analyses were performed to evaluate significance. aPDT significantly reduced microbial viability in a time- and dose-dependent manner. Optimal incubation times were 20 min for Candida spp. and 10 min for S. aureus, with the highest efficacy observed at 400 mW and 120 s irradiation. The photosensitizer or laser alone had no significant antimicrobial effect. Curcumin/riboflavin-mediated aPDT is a promising alternative or adjunctive approach to conventional antimicrobial therapy, particularly for resistant oral infections. Full article
(This article belongs to the Special Issue Recent Advances in Laser and Photodynamic Therapy)
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23 pages, 4593 KiB  
Article
Laser-Induced Liquid-Phase Boron Doping of 4H-SiC
by Gunjan Kulkarni, Yahya Bougdid, Chandraika (John) Sugrim, Ranganathan Kumar and Aravinda Kar
Materials 2025, 18(12), 2758; https://doi.org/10.3390/ma18122758 - 12 Jun 2025
Viewed by 471
Abstract
4H-silicon carbide (4H-SiC) is a cornerstone for next-generation optoelectronic and power devices owing to its unparalleled thermal, electrical, and optical properties. However, its chemical inertness and low dopant diffusivity for most dopants have historically impeded effective doping. This study unveils a transformative laser-assisted [...] Read more.
4H-silicon carbide (4H-SiC) is a cornerstone for next-generation optoelectronic and power devices owing to its unparalleled thermal, electrical, and optical properties. However, its chemical inertness and low dopant diffusivity for most dopants have historically impeded effective doping. This study unveils a transformative laser-assisted boron doping technique for n-type 4H-SiC, employing a pulsed Nd:YAG laser (λ = 1064 nm) with a liquid-phase boron precursor. By leveraging a heat-transfer model to optimize laser process parameters, we achieved dopant incorporation while preserving the crystalline integrity of the substrate. A novel optical characterization framework was developed to probe laser-induced alterations in the optical constants—refraction index (n) and attenuation index (k)—across the MIDIR spectrum (λ = 3–5 µm). The optical properties pre- and post-laser doping were measured using Fourier-transform infrared spectrometry, and the corresponding complex refraction indices were extracted by solving a coupled system of nonlinear equations derived from single- and multi-layer absorption models. These models accounted for the angular dependence in the incident beam, enabling a more accurate determination of n and k values than conventional normal-incidence methods. Our findings indicate the formation of a boron-acceptor energy level at 0.29 eV above the 4H-SiC valence band, which corresponds to λ = 4.3 µm. This impurity level modulated the optical response of 4H-SiC, revealing a reduction in the refraction index from 2.857 (as-received) to 2.485 (doped) at λ = 4.3 µm. Structural characterization using Raman spectroscopy confirmed the retention of crystalline integrity post-doping, while secondary ion mass spectrometry exhibited a peak boron concentration of 1.29 × 1019 cm−3 and a junction depth of 450 nm. The laser-fabricated p–n junction diode demonstrated a reverse-breakdown voltage of 1668 V. These results validate the efficacy of laser doping in enabling MIDIR tunability through optical modulation and functional device fabrication in 4H-SiC. The absorption models and doping methodology together offer a comprehensive platform for paving the way for transformative advances in optoelectronics and infrared materials engineering. Full article
(This article belongs to the Special Issue Laser Technology for Materials Processing)
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