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2 Results Found

  • Communication
  • Open Access
22 Citations
8,198 Views
11 Pages

6 March 2012

An efficient method for the synthesis of β-enaminones and β-enaminoesters using a combination of [(PPh3)AuCl]/AgOTf as catalyst has been developed. The reaction between 1,3-dicarbonyl compounds and primary amines was carried out under solvent-free co...

  • Article
  • Open Access
6 Citations
4,135 Views
20 Pages

Designing Potent Anti-Cancer Agents: Synthesis and Molecular Docking Studies of Thieno[2,3-d][1,2,4]triazolo[1,5-a]pyrimidine Derivatives

  • Eman S. M. Elsenbawy,
  • Zafer S. Alshehri,
  • Nouf A. Babteen,
  • Adel A.-H. Abdel-Rahman,
  • Mai A. El-Manawaty,
  • Eman S. Nossier,
  • Reem K. Arafa and
  • Nasser A. Hassan

29 February 2024

A new series of thieno[2,3-d][1,2,4]triazolo[1,5-a]pyrimidines was designed and synthesized using readily available starting materials, specifically, β-enaminoester. Their cytotoxicity was screened against three cancer cell lines, namely, MCF-7,...