Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

Article Types

Countries / Regions

Search Results (28)

Search Parameters:
Authors = Milad Masoud ORCID = 0000-0003-4359-3160

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
19 pages, 7639 KiB  
Article
Triple Filtering of Terrain Conductivity Data for Precise Tracing of Underground Utilities
by Mohamed Rashed, Abdulaziz Alqarawy, Nassir Al-Amri, Riyadh Halawani, Milad Masoud and Maged El Osta
Geosciences 2025, 15(5), 179; https://doi.org/10.3390/geosciences15050179 - 15 May 2025
Viewed by 303
Abstract
Terrain conductivity meters (TCMs) are efficient devices for different sorts of subsurface investigations, including detecting and tracing buried utilities, such as metallic pipes and cables. However, data collected using TCMs are usually ambiguous and hard to interpret. This ambiguity originates from the complex [...] Read more.
Terrain conductivity meters (TCMs) are efficient devices for different sorts of subsurface investigations, including detecting and tracing buried utilities, such as metallic pipes and cables. However, data collected using TCMs are usually ambiguous and hard to interpret. This ambiguity originates from the complex shape of apparent conductivity anomalies, the influence of irrelevant conductive bodies, and the interference of random noise with the collected data. To overcome this ambiguity and produce more interpretable apparent conductivity maps, a three-step filtering routine is proposed and tested using different real datasets. The filtering routine begins with applying a Savitzky–Golay (SG) filter to reduce the effect of random noise. This is followed by a modified rolling ball (MRB) filter to convert the complex M-shape of the anomaly into a single trough pointing to the underground utility. Finally, a virtual resolution enhancement (VRE) filter is applied to enhance the pinpointing apex of the trough. The application of the proposed filtering routine to apparent conductivity data collected using different terrain conductivity meters over different utilities in different urban environments shows a significant improvement of the data and an effective ability to reveal masked underground utilities. The proposed triple filtering routine can be a starting point for a new generation of TCMs with a built-in operation mode for instantaneous delineation and characterization of underground utilities in real time. Full article
(This article belongs to the Section Geophysics)
Show Figures

Figure 1

17 pages, 3472 KiB  
Article
A Hybrid Treatment System of the Coagulation/Flocculation/Settling Stage Followed by a Membrane Bioreactor (CFS-MBR) for Superior Removal of Cr and Nutrient Pollutants from Tannery Wastewater
by Hadis Saeedikia, Minoo Ghanbarzadeh, Milad Mahmoudzadeh, Manijeh Khorsi, Masoud Barani, Saeed Bazgir, Omid Tavakoli, Amir Heidarinasab, Geoffroy Lesage, Marc Heran and Farshid Pajoum Shariati
Water 2025, 17(10), 1432; https://doi.org/10.3390/w17101432 - 9 May 2025
Viewed by 627
Abstract
The effluent from the tannery industry contains high concentrations of organic pollutants, particularly chromium (Cr), which is a priority pollutant that harms human health, plants, animals, and affects compliance with environmental standards. This study significantly reduced tannery wastewater pollution and its toxic effects [...] Read more.
The effluent from the tannery industry contains high concentrations of organic pollutants, particularly chromium (Cr), which is a priority pollutant that harms human health, plants, animals, and affects compliance with environmental standards. This study significantly reduced tannery wastewater pollution and its toxic effects through the innovative use of an integrated treatment system with a coagulation/flocculation/settling process followed by a membrane bioreactor (MBR). Experiments were conducted to maximize the removal of pollutants by evaluating the effects of pH values, coagulant doses in the chemical treatment, and the biological treatment coupled with membrane separation within the MBR. The results indicated that optimizing the parameters achieved the highest reductions during the chemical treatment step: 97% for Cr, 63% for chemical oxygen demand (COD), and 90% for turbidity. The wastewater was then treated using the MBR system, which further improved removal efficiency to 99% for Cr, 96% for COD, and 99.8% for turbidity. These outcomes demonstrate the effectiveness of the hybrid treatment process in significantly lowering pollutant concentrations in tannery wastewater, ensuring compliance with Environmental Protection Agency (EPA) standards and the regulatory obligations under European Regulation (EU) 2020/741. This hybrid approach offers promising potential for broader industrial applications. Full article
(This article belongs to the Section Wastewater Treatment and Reuse)
Show Figures

Graphical abstract

17 pages, 4565 KiB  
Article
Groundwater Recharge Evaluation Using Stable Isotopes and the NETPATH Model in Al-Madinah Al-Munawarah Province, Saudi Arabia
by Milad Masoud, Maged El Osta, Nassir Al-Amri, Burhan Niyazi, Abdulaziz Alqarawy, Riyadh Halawani and Mohamed Rashed
Water 2025, 17(2), 211; https://doi.org/10.3390/w17020211 - 14 Jan 2025
Cited by 1 | Viewed by 1444
Abstract
In this study, hydrogeochemistry and environmentally stable isotopes were employed to examine the processes involved in recharging aquifer systems and the changes in the groundwater chemistry caused by the interaction between the water and the aquifer matrix. Based on data derived from 113 [...] Read more.
In this study, hydrogeochemistry and environmentally stable isotopes were employed to examine the processes involved in recharging aquifer systems and the changes in the groundwater chemistry caused by the interaction between the water and the aquifer matrix. Based on data derived from 113 groundwater wells, various tools and techniques, including stable environmental isotopes Oxygen-18 and Deuterium (δ18O and δD) for 33 samples and geochemical modeling with NETPATH, were used to evaluate the recharge mechanism and the evolution of the groundwater, combining GIS with hydrological and hydrochemical methods. The results revealed that groundwater from the Quaternary was the main source for irrigation; the water quality was categorized as relatively fresh to saline, with the total dissolved solids (TDSs) ranging from 261.3 to 8628.56 mg/L, exhibiting an average value of 2311.68 mg/L. The results of the environmental isotope analysis showed that the range of oxygen δ18O isotopes in the groundwater was from −5.65‰ to +0.39‰, while the range of hydrogen δD isotopes was from −32.60‰ to 4.73‰. Moreover, the δ18O–δD relationship indicated that the groundwater samples fell around the global meteoric precipitation line, showing a strong relationship, with a coefficient (R2) of approximately 0.82. The NETPATH model revealed that the dissolved chemical species within the groundwater system primarily originated from processes such as mineral weathering and dissolution, ion exchange, and evaporation. Full article
Show Figures

Figure 1

29 pages, 9301 KiB  
Article
Baffle-Enhanced Scour Mitigation in Rectangular and Trapezoidal Piano Key Weirs: An Experimental and Machine Learning Investigation
by Chonoor Abdi Chooplou, Ehsan Kahrizi, Amirhossein Fathi, Masoud Ghodsian and Milad Latifi
Water 2024, 16(15), 2133; https://doi.org/10.3390/w16152133 - 27 Jul 2024
Cited by 13 | Viewed by 1893
Abstract
The assessment of scour depth downstream of weirs holds paramount importance in ensuring the structural stability of these hydraulic structures. This study presents groundbreaking experimental investigations highlighting the innovative use of baffles to enhance energy dissipation and mitigate scour in the downstream beds [...] Read more.
The assessment of scour depth downstream of weirs holds paramount importance in ensuring the structural stability of these hydraulic structures. This study presents groundbreaking experimental investigations highlighting the innovative use of baffles to enhance energy dissipation and mitigate scour in the downstream beds of rectangular piano key weirs (RPKWs) and trapezoidal piano key weirs (TPKWs). By leveraging three state-of-the-art supervised machine learning algorithms—multi-layer perceptron (MLP), extreme gradient boosting (XGBoost), and support vector regression (SVR)—to estimate scour hole parameters, this research showcases significant advancements in predictive modeling for scour analysis. Experimental results reveal that the incorporation of baffles leads to a remarkable 18–22% increase in energy dissipation and an 11–14% reduction in scour depth for both RPKWs and TPKWs. Specifically, introducing baffles in RPKWs resulted in a noteworthy 26.7% reduction in scour hole area and a 30.3% decrease in scour volume compared to RPKWs without baffles. Moreover, novel empirical equations were developed to estimate scour parameters, achieving impressive performance metrics with an average R2 = 0.951, RMSE = 0.145, and MRPE = 4.429%. The MLP models demonstrate superior performance in predicting maximum scour depth across all scenarios with an average R2 = 0.988, RMSE = 0.035, and MRPE = 1.036%. However, the predictive capabilities varied when estimating weir toe scour depth under diverse circumstances, with the XGBoost model proving more accurate in scenarios involving baffled TPKWs with R2 = 0.965, RMSE = 0.048, and MRPE = 2.798% than the MLP and SVR models. This research underscores the significant role of baffles in minimizing scouring effects in TPKWs compared to RPKWs, showcasing the potential for improved design and efficiency in water-management systems. Full article
(This article belongs to the Section Water Erosion and Sediment Transport)
Show Figures

Figure 1

23 pages, 8137 KiB  
Article
SWAT-Driven Exploration of Runoff Dynamics in Hyper-Arid Region, Saudi Arabia: Implications for Hydrological Understanding
by Sajjad Hussain, Burhan Niyazi, Amro Mohamed Elfeki, Milad Masoud, Xiuquan Wang and Muhammad Awais
Water 2024, 16(14), 2043; https://doi.org/10.3390/w16142043 - 19 Jul 2024
Cited by 5 | Viewed by 1929
Abstract
Hydrological modeling plays a vital role in water-resource management and climate-change studies in hyper-arid regions. In the present investigation, surface runoff was estimated by a Soil and Water Assessment Tool (SWAT) model for Wadi Al-Aqul, Saudi Arabia. The Sequential Uncertainty Fitting version 2 [...] Read more.
Hydrological modeling plays a vital role in water-resource management and climate-change studies in hyper-arid regions. In the present investigation, surface runoff was estimated by a Soil and Water Assessment Tool (SWAT) model for Wadi Al-Aqul, Saudi Arabia. The Sequential Uncertainty Fitting version 2 (SUFI-2) technique in SWAT-CUP was adopted for the sensitivity analysis, calibration, and validation of the SWAT model’s components. The observational runoff data were scarce and only available from 1979 to 1984; such data scarcity is a common problem in hyper-arid regions. The results show good agreement with the observed daily runoff, as indicated by a Pearson Correlation Coefficient (r) of 0.86, a regression (R2) of 0.76, and a Nash–Sutcliffe coefficient (NSE) of 0.61. Error metrics, including the Mean Absolute Error (MAE) and Root Mean Square Error (RMSE), were notably low at 0.05 and 0.58, respectively. In the daily validation, the model continued to perform well, with a correlation of 0.76 and regression of 0.58. As a new approach, fitted parameters of daily calibration were incorporated into the monthly simulation, and they demonstrated an even better performance. The correlation coefficient (regression) and Nash–Sutcliffe were found to be extremely high during the calibration period of the monthly simulation, reaching 0.97 (0.95) and 0.73, respectively; meanwhile, they reached 0.99 (0.98) and 0.63 in the validation period, respectively. The sensitivity analysis using the SUFI-2 algorithm highlighted that, in the streamflow estimation, the Curve Number (CN) was found to be the most responsive parameter, followed by Soil Bulk Density (SOL_BD). Notably, the monthly results showed a higher performance than the daily results, indicating the inherent capability of the model in regard to data aggregation and reducing the impact of random fluctuations. These findings highlight the applicability of the SWAT model in predicting runoff and its implication for climate-change studies in hyper-arid regions. Full article
Show Figures

Figure 1

19 pages, 4478 KiB  
Article
Groundwater Characteristics’ Assessment for Productivity Planning in Al-Madinah Al-Munawarah Province, KSA
by Milad Masoud, Maged El Osta, Nassir Al-Amri, Burhan Niyazi, Abdulaziz Alqarawy and Mohamed Rashed
Hydrology 2024, 11(7), 99; https://doi.org/10.3390/hydrology11070099 - 8 Jul 2024
Cited by 3 | Viewed by 1560
Abstract
In recent times, drilling groundwater wells for irrigation, domestic, and industrial uses is increasing at a high rate in Saudi Arabia, meaning that groundwater is becoming a primary water resource. In the study region, over-exploitation and unsustainable performance severely deteriorate groundwater. Therefore, it [...] Read more.
In recent times, drilling groundwater wells for irrigation, domestic, and industrial uses is increasing at a high rate in Saudi Arabia, meaning that groundwater is becoming a primary water resource. In the study region, over-exploitation and unsustainable performance severely deteriorate groundwater. Therefore, it is important to monitor the groundwater levels and quality as well as to detect the hydraulic parameters in order to plan and maintain groundwater sustainability. Knowledge of aquifer hydraulic parameters and groundwater quality is essential for the productivity planning of an aquifer. Therefore, this study carried out a thorough analysis on measured depth to groundwater data (2017 and 2022), borehole pumping test records, and chemical analysis of the collected water samples, especially in the presence of overexploitation and scarcity of recharge scale. To accomplish this aim, measurements of 113 groundwater wells (including 103 water samples) and analysis of 29 pumping tests between step and long-duration tests were made of all aquifer characteristics. These parameters consist of well loss, formation loss, well efficiency, specific capacity, transmissivity, hydraulic conductivity, resulted drawdown, and physiochemical parameters. Thematic maps were generated for all parameters using the geographic information system (GIS) and diagrams to strategize the groundwater productivity in Al-Madinah Al-Munawarah Province. The estimated hydraulic parameters are highly variable. Four distinct portions were identified for aquifer potentiality based on these varying ranges. Both the north and east of the region are good for groundwater productivity due to good aquifer materials, whereas the southwestern and western portions have relatively poor values. The analyzed groundwater was categorized as fresh to slightly salty water, with two primary chemical types identified showing a prevalence of mixed NaCl and Ca-Mg-SO4/Cl water. Finally, groundwater productivity assessment predicts that the aquifers can support the Al-Madinah Al-Munawarah Province demand for several years if certain well distributions are adopted and for a few hours/day of pumping rate. The maps that have been created can be examined to aid in making decisions related to hydrology. Full article
Show Figures

Figure 1

16 pages, 3526 KiB  
Article
Experimental Investigation of Leakage Flow Rate and Fluidisation beneath Polyethylene Pipes in Non-Uniform Soils
by Shahab Sharafodin, Milad Latifi and Masoud Ghodsian
Water 2024, 16(8), 1156; https://doi.org/10.3390/w16081156 - 19 Apr 2024
Cited by 2 | Viewed by 1820
Abstract
Soil fluidisation around buried pipes is one of the water leakage effects that has a direct influence on the ultimate failure of pipelines. In this research, using a laboratory model, the fluidisation caused by water leakage from three cracks with three lengths (14, [...] Read more.
Soil fluidisation around buried pipes is one of the water leakage effects that has a direct influence on the ultimate failure of pipelines. In this research, using a laboratory model, the fluidisation caused by water leakage from three cracks with three lengths (14, 17, and 20 mm) and a 3 mm diameter hole for five pressures (1.5–5.5 bar) in non-uniform soils has been evaluated. The experiments were carried out both for pipes buried in soil, as well as exposed pipes. In the buried pipe tests, leakage flow rate, fluidisation, and mobile bed zone dimensions were investigated. The results showed that the increase in leakage flow rate due to an increase in pressure and crack length in exposed pipes is higher than in buried pipes. The exponent of the leakage–pressure relationship was obtained between 0.40 and 0.47 for the hole and between 0.8 and 1.9 in the crack. Observing different development patterns for fluidisation and mobile bed zones in cracks and holes, new relationships are presented for the height, width, and cross-sectional area of the leakage zones. Full article
(This article belongs to the Section Urban Water Management)
Show Figures

Figure 1

8 pages, 1588 KiB  
Proceeding Paper
Physics-Based Approach to Deep Interseismic Creep: Implications for North Tabriz Fault Behavior Using MCMC
by Milad Salmaniyan, Asghar Rastbood and Masoud Mashhadi Hossainali
Eng. Proc. 2023, 56(1), 26; https://doi.org/10.3390/ASEC2023-15239 - 26 Oct 2023
Cited by 1 | Viewed by 929
Abstract
Many studies assume that the distribution of a fault slip rate remains constant with time when examining surface deformation. However, recent numerical simulations have shown that dynamic rupture can penetrate regions with increased friction and diffuse from the lock-to-creep transition, contradicting this assumption. [...] Read more.
Many studies assume that the distribution of a fault slip rate remains constant with time when examining surface deformation. However, recent numerical simulations have shown that dynamic rupture can penetrate regions with increased friction and diffuse from the lock-to-creep transition, contradicting this assumption. Bruhat and Segall (2017) introduced a new method to account for the downward penetration of interseismic slip into the locked zone. This study builds upon their work by applying their model to strike-slip fault environments and incorporating creep coupling to viscoelastic flow in the lower crust and upper mantle. In this study, using Bruhat’s (2020) model, the interseismic deformation rates on the North Tabriz Fault are investigated. This study utilizes elastic and viscoelastic probabilistic models to fit horizontal surface rates. By employing this updated approach, a physics-based solution for deep interseismic creep is developed, revealing potential slow vertical propagation. The improved fit of horizontal deformation rates on the North Tabriz Fault is examined, leading to reasonable estimations of earthquake rupture depth and seismic displacement. The best-fit solutions suggest a half-space relaxation time of approximately 156 years, with a diffusion rate of less than 1 m/year and around 0.419 m/year, indicating minimal creep diffusion. Full article
(This article belongs to the Proceedings of The 4th International Electronic Conference on Applied Sciences)
Show Figures

Figure 1

22 pages, 7365 KiB  
Article
Application of Environmental Isotopes and Hydrochemistry to Identify the Groundwater Recharge in Wadi Qanunah Basin, Saudi Arabia
by Milad Masoud, Maged El Osta, Abdulaziz Alqarawy and Hesham Ezzeldin
Sustainability 2023, 15(3), 2648; https://doi.org/10.3390/su15032648 - 1 Feb 2023
Cited by 3 | Viewed by 2614
Abstract
The current study focuses on the Wadi Qanunah basin, which is considered one of Makkah Al-Mukarramah’s most important watersheds. It is located in the southwestern part of the Al Qunfudhah governorate. The identification and characterization of the recharging sources for the quaternary aquifer [...] Read more.
The current study focuses on the Wadi Qanunah basin, which is considered one of Makkah Al-Mukarramah’s most important watersheds. It is located in the southwestern part of the Al Qunfudhah governorate. The identification and characterization of the recharging sources for the quaternary aquifer is one of the most important goals of this study. In this context, different methods will be applied for the identification of the different factors impacting groundwater. Such methods will be based on the integration of geographic information system (GIS) and modern hydrochemical methods ranging from graphical plots, bivariate and multivariate analysis to geochemical modeling. The salinity of the groundwater studied varied from fresh to brackish, according to the seasonal influx of dilute runoff and the dissolution of the weathered rocks, as well as the cementing materials within the aquifers’ matrix. Ionic ratios indicated that ion exchange, silicate weathering and evaporation played a significant role in the enrichment of the groundwater with major constituents including calcium, sodium, magnesium, sulphate and chloride. Furthermore, four factors accounted for 73.92% of the total variance, calculated using SPSS’s statistical program. These factors accounted for leaching and dissolution, silicate and carbonate weathering, anthropogenic effects and evaporation. The δ18O vs. δD, TDS vs. δ18O and δ18O vs. d-excess relationships revealed that local rainfall is the main recharging source for groundwater; some samples were affected by evaporated rainfall, while others with lower salinity (<1000 mg/L) were diluted through seepage from the underlying fractured basement aquifer. Netpath geochemical modeling was applied to calculate the amount of evaporation or dilution which had affected an initial body of water as it moves from the upstream to downstream. The output of this program is consistent with what has been proved by stable isotopes, where the groundwater extracted from the final water is a mixture of an enriched recent precipitation with depleted older water. This study is an attempt to shed light on the assessment of groundwater and the extent at which it is affected by various factors in order to benefit from it in a way that ensures its sustainability. Full article
(This article belongs to the Special Issue Hydro-Meteorology and Its Application in Hydrological Modeling)
Show Figures

Figure 1

17 pages, 3313 KiB  
Article
Integrated Hydrogeochemical Groundwater Flow Path Modelling in an Arid Environment
by Milad Masoud, Natarajan Rajmohan, Jalal Basahi, Michael Schneider, Burhan Niyazi and Abdulaziz Alqarawy
Water 2022, 14(23), 3823; https://doi.org/10.3390/w14233823 - 23 Nov 2022
Cited by 3 | Viewed by 1900
Abstract
In this study, water-rock interaction, salinity sources, evolution, and the mixing of groundwater were modelled. The objectives of this research are to understand the hydrogeochemical factors that govern groundwater composition in a shallow aquifer system, Jazan Province, Saudi Arabia. The study aquifer is [...] Read more.
In this study, water-rock interaction, salinity sources, evolution, and the mixing of groundwater were modelled. The objectives of this research are to understand the hydrogeochemical factors that govern groundwater composition in a shallow aquifer system, Jazan Province, Saudi Arabia. The study aquifer is called a Quaternary aquifer, which is composed of gravel, sand, sandstone, and intercalated with some shale. In this study, 80 groundwater samples have been collected and analyzed for major ions and 30 representative samples were analyzed for Oxygen-18 (δ18O) and Deuterium (δD). NETPATH and environmental isotopes were integrated and applied to study the overall geochemical processes and to identify the salinity source in the groundwater. Saturation indices calculated for carbonates minerals indicates that 49%, 74%, and 61% of groundwater samples are undersaturated in terms of calcite, aragonite, and dolomite minerals, respectively. The remaining groundwater samples (51%, 39%, and 26%) are close to saturation with calcite, dolomite, and aragonite minerals, respectively. The saturation indices of gypsum, anhydrite, silica, strontionite, and sepiolite minerals show undersaturation in all groundwater samples, which is likely due to the dilution through the groundwater recharge from the surface runoff. In this study, water-rock interaction models were employed with the concentration of major ions of all selected groundwater samples, in addition to reference waters such as rain and sea waters, to evaluate the chemistry of groundwater in the flow path. Mixing calculations suggested that there is a variable contribution of rainwater (5% to 53%) in groundwater samples. The results indicate that evaporation and infiltration have a major impact on water chemistry in the study site. The intrusion of seawater at the coastal zone is well identified in some wells. Stable isotope data (δ18O and δD) support the results and underline the impact of evaporation processes on the groundwater and infiltration of evaporated water. Full article
(This article belongs to the Section Hydrology)
Show Figures

Figure 1

24 pages, 13149 KiB  
Article
Use of Hyperspectral Reflectance and Water Quality Indices to Assess Groundwater Quality for Drinking in Arid Regions, Saudi Arabia
by Abdulaziz Alqarawy, Maged El Osta, Milad Masoud, Salah Elsayed and Mohamed Gad
Water 2022, 14(15), 2311; https://doi.org/10.3390/w14152311 - 25 Jul 2022
Cited by 40 | Viewed by 5428
Abstract
Combining hydrogeochemical characterization and a hyperspectral reflectance measurement can provide knowledge for groundwater security under different conditions. In this study, comprehensive examinations of 173 groundwater samples were carried out in Makkah Al-Mukarramah Province, Saudi Arabia. Physicochemical parameters, water quality indices (WQIs), and spectral [...] Read more.
Combining hydrogeochemical characterization and a hyperspectral reflectance measurement can provide knowledge for groundwater security under different conditions. In this study, comprehensive examinations of 173 groundwater samples were carried out in Makkah Al-Mukarramah Province, Saudi Arabia. Physicochemical parameters, water quality indices (WQIs), and spectral reflectance indices (SRIs) were combined to investigate water quality and controlling factors using multivariate modeling techniques, such as partial least-square regression (PLSR) and principal component regression (PCR). To measure water quality status, the drinking water quality index (DWQI), total dissolved solids (TDS), heavy metal index (HPI), contamination degree (Cd), and pollution index (PI) were calculated. Standard analytical methods were used to assess nineteen physicochemical parameters. The typical values of ions and metals were as follows: Na2+ > Ca2+ > Mg2+ > K+, Cl > SO42− > HCO3 > NO3 > CO32−; and Cu > Fe > Al > Zn > Mn > Ni, respectively. The hydrogeochemical characteristics of the examined groundwater samples revealed that Ca-HCO3, Na-Cl, mixed Ca-Mg-Cl-SO4, and Na-Ca-HCO3 were the main mechanisms governing groundwater chemistry and quality under the load of seawater intrusion, weathering, and water-rock interaction. According to the WQIs results, the DWQI values revealed that 2.5% of groundwater samples were categorized as excellent, 18.0% as good, 28.0% as poor, 21.5% as extremely poor, and 30.0% as unfit for drinking. The HPI and Cd values revealed that all groundwater samples had a low degree of contamination and better quality. Furthermore, the PI values showed that the groundwater resources were not affected by metals but were slightly affected by Mn in Wadi Fatimah due to rock–water interaction. Linear regression models demonstrated the significant relationships for the majority of SRIs paired with DWQI (R varied from −0.40 to 0. 75), and with TDS (R varied from 0.46 to 0.74) for the studied wadies. In general, the PLSR and PCR models provide better estimations for DWQI and TDS than the individual SRI. In conclusion, the grouping of WQIs, SRIs, PLSR, PCR, and GIS tools provides a clear image of groundwater suitability for drinking and its controlling elements. Full article
(This article belongs to the Section Water Quality and Contamination)
Show Figures

Figure 1

21 pages, 9549 KiB  
Article
A Comparative Analysis of Infiltration Models for Groundwater Recharge from Ephemeral Stream Beds: A Case Study in Al Madinah Al Munawarah Province, Saudi Arabia
by Burhan Niyazi, Milad Masoud, Amro Elfeki, Natarajan Rajmohan, Abdulaziz Alqarawy and Mohamed Rashed
Water 2022, 14(11), 1686; https://doi.org/10.3390/w14111686 - 25 May 2022
Cited by 11 | Viewed by 3710
Abstract
Groundwater recharge is strongly influenced by the infiltration process. In this research, the Philip, Horton, Kostiakov, and Green–Ampt infiltration models were tested for the ability to describe the infiltration process in the ephemeral stream beds located in Al Madinah Al Munawarah Province in [...] Read more.
Groundwater recharge is strongly influenced by the infiltration process. In this research, the Philip, Horton, Kostiakov, and Green–Ampt infiltration models were tested for the ability to describe the infiltration process in the ephemeral stream beds located in Al Madinah Al Munawarah Province in Saudi Arabia. Infiltration data were obtained from double-ring infiltrometer tests in 14 locations distributed over the province. The method of least squares through an objective function optimization formalism is utilized to estimate the parameters of each model. The results show high variability in the parameters of each model over the tests. Individual tests showed that some models were better for representing specific tests than other models. On average, the Kostiakov empirical model was the best at describing the 14 infiltration tests with only 2 empirical parameters, since it had the minimum root mean square error (RMSE) for the cumulative infiltration depth F (1.13 cm), and it also had the same RMSE for the infiltration rates f (0.1 cm/min), similar to other models. Moreover, the Kostiakov model had an acceptable correlation coefficient R = 0.61 for f, and R = 0.99 for F. The results imply significant variability in the groundwater recharge rates from flash floods in the region. Full article
(This article belongs to the Section Hydrogeology)
Show Figures

Figure 1

23 pages, 9259 KiB  
Article
Groundwater Suitability for Drinking and Irrigation Using Water Quality Indices and Multivariate Modeling in Makkah Al-Mukarramah Province, Saudi Arabia
by Maged El Osta, Milad Masoud, Abdulaziz Alqarawy, Salah Elsayed and Mohamed Gad
Water 2022, 14(3), 483; https://doi.org/10.3390/w14030483 - 6 Feb 2022
Cited by 121 | Viewed by 8960
Abstract
Water shortage and quality are major issues in many places, particularly arid and semi-arid regions such as Makkah Al-Mukarramah province, Saudi Arabia. The current work was conducted to examine the geochemical mechanisms influencing the chemistry of groundwater and assess groundwater resources through several [...] Read more.
Water shortage and quality are major issues in many places, particularly arid and semi-arid regions such as Makkah Al-Mukarramah province, Saudi Arabia. The current work was conducted to examine the geochemical mechanisms influencing the chemistry of groundwater and assess groundwater resources through several water quality indices (WQIs), GIS methods, and the partial least squares regression model (PLSR). For that, 59 groundwater wells were tested for different physical and chemical parameters using conventional analytical procedures. The results showed that the average content of ions was as follows: Na+ > Ca2+ > Mg 2+ > K+ and Cl > SO42− > HCO32− > NO3 > CO3. Under the stress of evaporation and saltwater intrusion associated with the reverse ion exchange process, the predominant hydrochemical facies were Ca-HCO3, Na-Cl, mixed Ca-Mg-Cl-SO4, and Na-Ca-HCO3. The drinking water quality index (DWQI) has indicated that only 5% of the wells were categorized under good to excellent for drinking while the majority (95%) were poor to unsuitable for drinking, and required appropriate treatment. Furthermore, the irrigation water quality index (IWQI) has indicated that 45.5% of the wells were classified under high to severe restriction for agriculture, and can be utilized only for high salt tolerant plants. The majority (54.5%) were deemed moderate to no restriction for irrigation, with no toxicity concern for most plants. Agriculture indicators such as total dissolved solids (TDS), potential salinity (PS), sodium absorption ratio (SAR), and residual sodium carbonate (RSC) had mean values of 2572.30, 33.32, 4.84, and −21.14, respectively. However, the quality of the groundwater in the study area improves with increased rainfall and thus recharging the Quaternary aquifer. The PLSR models, which are based on physicochemical characteristics, have been shown to be the most efficient as alternative techniques for determining the six WQIs. For instance, the PLSR models of all IWQs had determination coefficients values of R2 ranging between 0.848 and 0.999 in the Cal., and between 0.848 and 0.999 in the Val. datasets, and had model accuracy varying from 0.824 to 0.999 in the Cal., and from 0.817 to 0.989 in the Val. datasets. In conclusion, the combination of physicochemical parameters, WQIs, and multivariate modeling with statistical analysis and GIS tools is a successful and adaptable methodology that provides a comprehensive picture of groundwater quality and governing mechanisms. Full article
(This article belongs to the Special Issue Water Quality Modeling and Monitoring)
Show Figures

Figure 1

10 pages, 587 KiB  
Article
Evaluation of the Expression of miR-486-3p, miR-548-3p, miR-561-5p and miR-509-5p in Tumor Biopsies of Patients with Oral Squamous Cell Carcinoma
by Ata Garajei, Milad Parvin, Hady Mohammadi, Abdolamir Allameh, Azin Hamidavi, Masoud Sadeghi, Azadeh Emami and Serge Brand
Pathogens 2022, 11(2), 211; https://doi.org/10.3390/pathogens11020211 - 5 Feb 2022
Cited by 14 | Viewed by 2481
Abstract
Background and objective: Oral squamous cell carcinoma (OSCC) is the most common head and neck malignancy. Expression patterns of microRNAs (miRNAs) can direct us in identifying valuable biomarkers for the prognosis of different neoplasms. Inappropriate regulation of miRNAs during physiological procedures can result [...] Read more.
Background and objective: Oral squamous cell carcinoma (OSCC) is the most common head and neck malignancy. Expression patterns of microRNAs (miRNAs) can direct us in identifying valuable biomarkers for the prognosis of different neoplasms. Inappropriate regulation of miRNAs during physiological procedures can result in malignancies including OSCC. The aim of the present study was to evaluate the expression of miR-486-3p, miR-561-5p, miR-548-3p, and miR-509-5p in tissue biopsy samples with and without OSCC. Materials and methods: This case-control study was conducted on 17 healthy and 17 OSCC tissue biopsy samples. The expression of miRNAs was assessed using quantitative real-time PCR (q-RT-PCR) after RNA extraction from normal and cancer tissues and cDNA synthesis. Results: The means of miRNA-486-3p, miR-561-5p, and miR-548-3p expression were significantly different between OSCC and control groups (p < 0.001), but there was no significant difference in means of miR-509-5p expression between OSCC and control groups (p = 0.179). Conclusions: The findings of this study revealed that the expression of miR-486-3p and miR-561-5p was significantly lower in cancer samples compared to normal tissue samples. On the other hand, miR-548-3p expression increased in the OSCC group compared to the control group. Full article
(This article belongs to the Special Issue Biomarkers in Oral Diseases)
Show Figures

Figure 1

37 pages, 3124 KiB  
Review
Pre-Clinical and Clinical Applications of Small Interfering RNAs (siRNA) and Co-Delivery Systems for Pancreatic Cancer Therapy
by Sepideh Mirzaei, Mohammad Hossein Gholami, Hui Li Ang, Farid Hashemi, Ali Zarrabi, Amirhossein Zabolian, Kiavash Hushmandi, Masoud Delfi, Haroon Khan, Milad Ashrafizadeh, Gautam Sethi and Alan Prem Kumar
Cells 2021, 10(12), 3348; https://doi.org/10.3390/cells10123348 - 29 Nov 2021
Cited by 47 | Viewed by 6978
Abstract
Pancreatic cancer (PC) is one of the leading causes of death and is the fourth most malignant tumor in men. The epigenetic and genetic alterations appear to be responsible for development of PC. Small interfering RNA (siRNA) is a powerful genetic tool that [...] Read more.
Pancreatic cancer (PC) is one of the leading causes of death and is the fourth most malignant tumor in men. The epigenetic and genetic alterations appear to be responsible for development of PC. Small interfering RNA (siRNA) is a powerful genetic tool that can bind to its target and reduce expression level of a specific gene. The various critical genes involved in PC progression can be effectively targeted using diverse siRNAs. Moreover, siRNAs can enhance efficacy of chemotherapy and radiotherapy in inhibiting PC progression. However, siRNAs suffer from different off target effects and their degradation by enzymes in serum can diminish their potential in gene silencing. Loading siRNAs on nanoparticles can effectively protect them against degradation and can inhibit off target actions by facilitating targeted delivery. This can lead to enhanced efficacy of siRNAs in PC therapy. Moreover, different kinds of nanoparticles such as polymeric nanoparticles, lipid nanoparticles and metal nanostructures have been applied for optimal delivery of siRNAs that are discussed in this article. This review also reveals that how naked siRNAs and their delivery systems can be exploited in treatment of PC and as siRNAs are currently being applied in clinical trials, significant progress can be made by translating the current findings into the clinical settings. Full article
Show Figures

Figure 1

Back to TopTop