Biomolecules | Highly Cited Papers in 2024–2025 in the “Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates” Section

We welcome you to read our most highly cited papers published in 2024 and 2025, which are listed below. As all of the articles published in Biomolecules (ISSN: 2218-273X) are open access, you have free and unlimited access to the full text.

1. “LL-37: Structures, Antimicrobial Activity, and Influence on Amyloid-Related Diseases”
by Surajit Bhattacharjya, Zhizhuo Zhang and Ayyalusamy Ramamoorthy
Biomolecules 2024, 14(3), 320; https://doi.org/10.3390/biom14030320
Full text available online: https://www.mdpi.com/2218-273X/14/3/320

2. “Morphological and Biophysical Study of S100A9 Protein Fibrils by Atomic Force Microscopy Imaging and Nanomechanical Analysis”
by Ana P. Carapeto, Carlos Marcuello, Patrícia F. N. Faísca and Mário S. Rodrigues
Biomolecules 2024, 14(9), 1091; https://doi.org/10.3390/biom14091091
Full text available online: https://www.mdpi.com/2218-273X/14/9/1091

3. “The RAGE Axis: A Relevant Inflammatory Hub in Human Diseases”
by Armando Rojas, Cristian Lindner, Ivan Schneider, Ileana Gonzalez and Jaime Uribarri
Biomolecules 2024, 14(4), 412; https://doi.org/10.3390/biom14040412
Full text available online: https://www.mdpi.com/2218-273X/14/4/412

4. “Inhibitors of SARS-CoV-2 Main Protease (Mpro) as Anti-Coronavirus Agents”
by Agnieszka Zagórska, Anna Czopek, Monika Fryc and Jakub Jończyk
Biomolecules 2024, 14(7), 797; https://doi.org/10.3390/biom14070797
Full text available online: https://www.mdpi.com/2218-273X/14/7/797

5. “Current Technologies Unraveling the Significance of Post-Translational Modifications (PTMs) as Crucial Players in Neurodegeneration”
by Saima Zafar, Shehzadi Irum Fatima, Matthias Schmitz and Inga Zerr
Biomolecules 2024, 14(1), 118; https://doi.org/10.3390/biom14010118
Full text available online: https://www.mdpi.com/2218-273X/14/1/118

6. “The Metabolism of Creatinine and Its Usefulness to Evaluate Kidney Function and Body Composition in Clinical Practice”
by Marcela Ávila, Mariana G. Mora Sánchez, Alma Sofía Bernal Amador and Ramón Paniagua
Biomolecules 2025, 15(1), 41; https://doi.org/10.3390/biom15010041
Full text available online: https://www.mdpi.com/2218-273X/15/1/41

7. “Enkephalins and Pain Modulation: Mechanisms of Action and Therapeutic Perspectives”
by Mario García-Domínguez
Biomolecules 2024, 14(8), 926; https://doi.org/10.3390/biom14080926
Full text available online: https://www.mdpi.com/2218-273X/14/8/926

8. “Structures of Toxic Advanced Glycation End-Products Derived from Glyceraldehyde, A Sugar Metabolite”
by Akiko Sakai-Sakasai, Kenji Takeda, Hirokazu Suzuki and Masayoshi Takeuchi
Biomolecules 2024, 14(2), 202; https://doi.org/10.3390/biom14020202
Full text available online: https://www.mdpi.com/2218-273X/14/2/202

9. “Role of the Receptor for Advanced Glycation End Products (RAGE) and Its Ligands in Inflammatory Responses”
by Kaylen Cross, Stefan W. Vetter, Yousuf Alam, Md. Zahidul Hasan, Anupom Deb Nath and Estelle Leclerc
Biomolecules 2024, 14(12), 1550; https://doi.org/10.3390/biom14121550
Full text available online: https://www.mdpi.com/2218-273X/14/12/1550

10. “Advancements in the Application of Ribosomally Synthesized and Post-Translationally Modified Peptides (RiPPs)”
by Sang-Woo Han and Hyung-Sik Won
Biomolecules 2024, 14(4), 479; https://doi.org/10.3390/biom14040479
Full text available online: https://www.mdpi.com/2218-273X/14/4/479