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Veterinary Sciences
Special Issues
Diagnosis and Epidemiology of Cattle Infectious Diseases
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Diagnosis and Epidemiology of Cattle Infectious Diseases

A special issue of Veterinary Sciences (ISSN 2306-7381). This special issue belongs to the section "Veterinary Food Safety and Zoonosis".

Deadline for manuscript submissions: 30 July 2026 | Viewed by 2947

Special Issue Editor

Prof. Dr. Aizhen Guo

E-Mail Website
Guest Editor
College of Veterinary Medicine, The State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China
Interests: cattle infectious diseases; vaccine; diagnosis; epidemiology; biosafety; zoonosis; tuberculosis; mycoplasmosis; BVDV; IBRV
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The cattle industry is a pillar industry in animal husbandry, providing people with high-quality food, protein, and nutrition, such as milk and beef. However, infectious diseases are an important factor restricting the benefits of cattle farming and are also an important factor affecting food safety, public health, and the healthy and sustainable development of the cattle industry.

The journal Veterinary Sciences has launched a Special Issue on the "Diagnosis and Epidemiology of Cattle Infectious Diseases", aiming to gather the latest research results in this field, promote the theoretical and technological progress of cattle infectious disease prevention and control, and promote the improvement of clinical prevention and control skills.

Prof. Dr. Aizhen Guo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Veterinary Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cattle
  • infectious diseases
  • diagnosis
  • epidemiology
  • tuberculosis
  • mycoplasmosis
  • BVDV
  • IBRV

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Published Papers (3 papers)

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Research

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16 pages, 346 KB  
Article
Johne’s Disease Control in Beef Cattle: Balancing Test-and-Cull Strategies with Economic and Epidemiological Trade-Offs
by Leigh Rosengren, Steven M. Roche, Kathy Larson and Cheryl L. Waldner
Vet. Sci. 2025, 12(12), 1210; https://doi.org/10.3390/vetsci12121210 - 17 Dec 2025
Viewed by 1276
Abstract
Johne’s disease (JD) is a chronic infection of cattle that undermines herd productivity and profitability. While test-and-cull programs are commonly proposed for control, their effectiveness and economic feasibility remain uncertain in beef production systems. This study used an updated agent-based model (ABM) to [...] Read more.
Johne’s disease (JD) is a chronic infection of cattle that undermines herd productivity and profitability. While test-and-cull programs are commonly proposed for control, their effectiveness and economic feasibility remain uncertain in beef production systems. This study used an updated agent-based model (ABM) to simulate JD transmission in a representative 300-cow Western Canadian beef herd, coupled with a partial budget model to evaluate net present value (NPV) over a 10-year time horizon. Seven diagnostic test-and-cull strategies were compared, varying in test type (ELISA, individual PCR, and pooled PCR), sampling frequency (6, 12, or 24 mo), and risk-based sampling protocols. Results showed that, under baseline assumptions (6% starting prevalence; 1% prevalence in purchased stock), all strategies reduced JD prevalence relative to no testing, and six of seven yielded higher NPVs. Annual individual PCR testing provided the best balance between prevalence reduction and profitability, whereas semi-annual PCR most effectively reduced prevalence but at greater economic cost. Failure to implement control measures resulted in increasing prevalence and long-term economic losses. Sensitivity analyses demonstrated that strategy performance was consistent across variations in market conditions, cost of production, and replacement female management, although profitability declined substantially when JD prevalence in externally sourced stock was high (i.e., 10%). Collectively, these findings indicate that JD can be controlled economically in beef herds, with long-term application of various test-and-cull strategies offering robust options adaptable to management preferences. Full article
(This article belongs to the Special Issue Diagnosis and Epidemiology of Cattle Infectious Diseases)

Review

Jump to: Research, Other

20 pages, 563 KB  
Review
Bovine Tuberculosis as a Neglected Zoonotic Disease in Mexico and Latin America: Epidemiological Challenges, Diagnostic Insights, and Public Health Implications in Emerging Economies
by Luis M. Rodríguez-Martínez, Jose L. Chavelas-Reyes, Carlo F. Medina-Ramírez, Jorge A. Valdés-González, Eli Fuentes-Chávez, Carlos A. Ríos-Saldaña, Miguel A. de León-Zapata and Josefina G. Rodríguez-González
Vet. Sci. 2026, 13(3), 259; https://doi.org/10.3390/vetsci13030259 - 11 Mar 2026
Viewed by 793
Abstract
Bovine tuberculosis (bTB), caused by Mycobacterium bovis, remains one of the most relevant zoonotic diseases worldwide due to its dual impact on livestock production and human health. Although zoonotic tuberculosis has been virtually eradicated from cattle in a few settings, particularly in [...] Read more.
Bovine tuberculosis (bTB), caused by Mycobacterium bovis, remains one of the most relevant zoonotic diseases worldwide due to its dual impact on livestock production and human health. Although zoonotic tuberculosis has been virtually eradicated from cattle in a few settings, particularly in Australia, the disease persists in much of Latin America, Africa, and Asia, where it continues to limit cattle productivity and pose a threat to public health through the consumption of unpasteurized dairy products and occupational exposure. This review integrates historical, epidemiological, clinical, and molecular perspectives of bTB, with particular emphasis on Mexico, highlighting the role of wildlife reservoirs, socioeconomic factors, and diagnostic limitations in maintaining endemicity. Recent advances in molecular epidemiology, such as PCR, MIRU-VNTR, and whole-genome sequencing, provide promising avenues for surveillance and control. Finally, we discuss the importance of adopting a One Health framework that bridges veterinary, medical, and environmental approaches to achieve sustainable control of this silent zoonosis. Full article
(This article belongs to the Special Issue Diagnosis and Epidemiology of Cattle Infectious Diseases)
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Other

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11 pages, 2895 KB  
Brief Report
Prevalence and Genetic Characterization of Mammalian Orthoreoviruses in Diarrheic Cattle from Guangxi, China
by Haonan Yu, Yuhang Luo, Zhen Liao, Li Fan, Haolan Zhong, Kang Ouyang, Ying Chen, Yeshi Yin, Zuzhang Wei, Yifeng Qin, Qingting Dong, Yan Pan and Weijian Huang
Vet. Sci. 2026, 13(3), 225; https://doi.org/10.3390/vetsci13030225 - 27 Feb 2026
Viewed by 406
Abstract
Mammalian orthoreoviruses (MRVs) infect a wide range of animal hosts, yet epidemiological data from southern China remain limited. Here, we performed regional screening of diarrheic cattle in Guangxi, China, from 2023 to 2025. Using L1-targeted RT-PCR, MRV was detected in 8.4% (15/178) of [...] Read more.
Mammalian orthoreoviruses (MRVs) infect a wide range of animal hosts, yet epidemiological data from southern China remain limited. Here, we performed regional screening of diarrheic cattle in Guangxi, China, from 2023 to 2025. Using L1-targeted RT-PCR, MRV was detected in 8.4% (15/178) of fecal specimens collected across eight prefectures, with a higher detection rate during the cool (autumn–winter) season (October–March). We obtained two complete S1 segments, assigning one Guangxi strain to MRV1 and the other to MRV3. Phylogenetic analysis of L1 sequences indicated a single local lineage nested within a broader multi-host cluster, which was consistent with segment reassortment. σ1 protein alignment revealed a conserved central/C-terminal scaffold and a variable distal head; notably, the MRV3 σ1 sequence contained an extended ~360–390 aa region compared with MRV1. Overall, these findings provide an epidemiological baseline for Guangxi cattle, integrating detection rate, serotype context, and seasonality to support targeted, seasonally informed surveillance and MRV risk assessment. Full article
(This article belongs to the Special Issue Diagnosis and Epidemiology of Cattle Infectious Diseases)
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