Immunity and Inflammatory Processes in Renal Diseases

Dear Colleagues,

Renal diseases encompass a wide spectrum of conditions, from primary and secondary glomerulonephritis and acute and chronic kidney disease to renal replacement therapies (including kidney transplantation).

The underlying pathogenetic mechanisms, including dysregulation of both innate and adaptative immune systems, hypoxia, oxidative stress, inflammatory processes, metabolic alterations, and changes in cellular and molecular pathways, are multifaceted and strictly inter-related.

Historically, immunity and inflammatory processes have been recognized to play a relevant role in the pathogenesis of renal diseases and contribute significantly to the development of complications and disease progression.

However, increasing evidence from experimental and clinical studies highlights that these processes are more complex than previously thought and may be implicated in emerging renal-disease-related complications, such as early senescence and vascular calcification.

The characterization of new pathogenetic mechanisms and advances in our understanding of the pathophysiology of renal diseases might provide new therapeutic targets to improve the management of these high-clinical-impact conditions.

For this Special Issue of the Transplantology, we invite the submission of original research papers and review articles on the involvement of immunity and inflammatory processes in specific areas of investigation, including:

- the pathogenesis of primary or secondary glomerular disease;
- recurrence of primary or secondary glomerular disease after kidney transplantation;
- therapeutic approaches to primary or secondary glomerular disease in native and transplanted kidney;
- risk of infection or cancer in patients with renal disease or kidney transplant;
- vascular calcification;
- diabetes kidney disease and new-onset diabetes after transplantation;
- acute or chronic kidney disease;
- renal anemia;
- muscle atrophy;
- complications of hemodialysis or peritoneal dialysis; and
- complications of kidney transplantation
- pathogenesis, clinical presentation and treatment of acute and chronic kidney graft rejection.

You may choose our Joint Special Issue in JCM.

Prof. Dr. Pasquale Esposito
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Transplantology is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.