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Transplantology, Volume 7, Issue 2

2026 June - 7 articles

Cover Story: The best treatment for end-stage renal failure is kidney transplantation; however, the shortage of deceased donors limits its availability. Living donor transplantation is a valuable alternative, yet it is often hindered by immunological incompatibility, most frequently involving the ABO system. ABO glycoproteins are present on erythrocytes, endothelial cells, and kidney cells. Anti-blood group antibodies are formed against absent antigens, causing antibody-mediated rejection. About 30% of potential living donations are prevented by ABO antibodies. For a long time, ABO incompatibility was a formal contraindication. Recently, strategies have enabled ABO-incompatible transplantation, including kidney paired donation, desensitization (most commonly used), and enzymatic blood group conversion (the newest and most promising approach). View this paper
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Articles (7)

  • Article
  • Open Access
775 Views
14 Pages

One-Year Outcomes of Kidney and Liver Transplantation from Drug Overdose Donors Before and During the COVID-19 Pandemic

  • Dominique Betterbed,
  • Sohail Khan,
  • Riah Lee,
  • Bhavin Patel and ,
  • Aileen Xue,
  • Melis Ozdemir,
  • Momo Tun,
  • Ali Andalibi,
  • Yang Yu and
  • Jorge Ortiz
  • + 6 authors+ 1 author

Introduction: During the COVID-19 pandemic, drug overdose deaths increased significantly, providing a potential cohort of donor organs. However, graft failure and mortality rates among those receiving organs from donors who died from drug overdose re...

(This article belongs to the Section Organ and Tissue Donation and Preservation)
  • Review
  • Open Access
1,584 Views
21 Pages

A Review of Risk Assessment in the Evolving Heart Transplant Landscape

  • Lyana Labrada,
  • Mihir Shah,
  • Pooja Saiganesh,
  • Maha Inam and
  • Eman Hamad

Heart transplantation remains a vital therapy for patients with end-stage heart failure, yet organ scarcity and evolving allocation policies necessitate robust risk prediction models to optimize outcomes and equity. This narrative review explores the...

(This article belongs to the Special Issue New Horizons in Transplantation Research: A Review Series)
  • Review
  • Open Access
1,692 Views
24 Pages

Inflammatory and Immune Pathways in Kidney Transplant Rejection: Current Evidence and Future Perspectives

  • Petar Todorović,
  • Anita Racetin,
  • Azer Rizikalo,
  • Ivona Letica and ,
  • Fila Raguž,
  • Katarina Vukojević and
  • Nela Kelam
  • + 2 authors+ 0 author

Kidney transplantation remains the optimal treatment for end-stage renal disease, yet long-term allograft survival has plateaued due to persistent rejection. This review provides a comprehensive overview of the inflammatory and immune pathways implic...

(This article belongs to the Special Issue New Horizons in Transplantation Research: A Review Series)
  • Review
  • Open Access
1,675 Views
13 Pages

Kidney transplantation is considered the best therapeutic option for patients affected by end-stage renal failure, but this possibility is limited by a shortage of donors. Living-donor kidney transplantation (LDKD) is a valuable option, frequently li...

(This article belongs to the Special Issue New Horizons in Transplantation Research: A Review Series)
  • Article
  • Open Access
1,246 Views
12 Pages

99mTc-MAG3 Scintigraphy Within 48 h of Kidney Transplantation Predicts Long-Term Graft Survival: A Retrospective Single-Center Cohort Study

  • Joseba Salguero,
  • Laura Chamorro,
  • Juan Marquez,
  • Enrique Gomez-Gomez and ,
  • Javier A. Cienfuegos,
  • Juan P. Campos,
  • Juan A. Vallejo and
  • Jose E. Robles
  • + 3 authors+ 0 author

Background/Objectives: Renal scintigraphy with 99mTc-MAG3 is a non-invasive tool for assessing early post-kidney-transplant function and detecting complications. While its utility in predicting delayed graft function (DGF) is established, evidence re...

(This article belongs to the Section Perioperative Patient Management (i.e. Preabilitation, Intensive Care Management, Complications))
  • Article
  • Open Access
2,223 Views
20 Pages

Background/Objectives: Given the narrow therapeutic range of tacrolimus and substantial inter-individual variability in trough levels, both total daily dose and the trough level-to-dose ratio are commonly used to guide dose optimization. In this stud...

(This article belongs to the Section Solid Organ Transplantation)
  • Article
  • Open Access
1,018 Views
10 Pages

Relationship Between Numbers of Patients Registered and Procedures Performed at Lung Transplantation Centers in Japan

  • Takashi Inoue,
  • Masayuki Chida,
  • Yoshinori Okada,
  • Masaaki Sato and ,
  • Hidemi Suzuki,
  • Yasushi Hoshikawa,
  • Toyofumi Chen-Yoshikawa,
  • Daisuke Nakajima,
  • Yasushi Sintani and
  • Sumiko Maeda
  • + 11 authors+ 6 authors

Background: Recently, there has been a dramatic increase in deceased lung transplantation (DLT) procedures performed in Japan. However, there is concern that the number of transplantations may reach the limit of capacity in some centers. The present...

(This article belongs to the Section Solid Organ Transplantation)
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Transplantology - ISSN 2673-3943