Special Issue "Metabolism of Mycotoxins by Animals and Microbes"
Deadline for manuscript submissions: 1 May 2021.
The more we know about the metabolism and biochemistry of mycotoxins, the better the exposure to mycotoxins can be assessed and the better the negative effects caused by mycotoxins can be mitigated. Studying the metabolism of mycotoxins can lead to the discovery of novel biomarkers for estimating mycotoxin exposure. Likewise, knowledge of metabolization is crucial in the toxicity assessment of mycotoxins in different animal species. Furthermore, investigating the metabolization of mycotoxins by microbes is a vital part in the discovery and development of mycotoxin inactivators.
While the in vivo fate of selected mycotoxins has been extensively studied, the metabolism of other mycotoxins has at best only partly been elucidated. In addition, for some of the well-investigated mycotoxins, great differences in metabolism have been discovered between animal species. For instance, when only glucuronidation was considered as a metabolization pathway of deoxynivalenol (DON) in animals, biological recoveries of DON were below 20% in species such as cows, rats and chickens. The microbial transformation by de-epoxidation and, as only recently demonstrated, the pathways of sulfation and sulfonation provided the missing link. Considering that it took decades to elucidate the in vivo fate of one of the most common and most studied mycotoxins, more timely research on the metabolism of other mycotoxins is warranted.
This Special Issue of Toxins on ‘Metabolism of Mycotoxins by Animals and Microbes’ aims to provide a comprehensive overview of all topics related to the metabolism of mycotoxins. These include, among others, animal experiments on the metabolism of masked or emerging mycotoxins, ADME studies of mycotoxins in different animal species, toxicological studies in vivo and in vitro, the analytical methodologies involved, detoxification strategies based on microbial action, in vivo testing of feed additives, and biomarker research.
Dr. Heidi E. Schwartz-Zimmermann
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Mycotoxin biomarkers
- Analytical methods
- In vivo
- In vitro