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Toxics
Special Issues
Human Biomonitoring and Exposure Assessment of Environmental Contaminants
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Human Biomonitoring and Exposure Assessment of Environmental Contaminants

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Human Toxicology and Epidemiology".

Deadline for manuscript submissions: closed (20 November 2024) | Viewed by 1379

Special Issue Editors

Dr. Shanshan Yin

E-Mail Website1 Website2
Guest Editor
1. Interdisciplinary Research Academy, Zhejiang Shuren University, Hangzhou 310015, China
2. Toxicological Centre, University of Antwerp, 2610 Wilrijk, Belgium
Interests: exposure sciences; aggregate exposure pathways; emerging POPs; environmental chemistry; environmental toxicology; analytical chemistry; polychlorinated alkanes; human biomonitoring; exposome
Special Issues, Collections and Topics in MDPI journals
Dr. Chenye Xu

E-Mail Website
Guest Editor
College of Environmental Science and Engineering, Donghua University, Shanghai 201620, China
Interests: microplastic; PFAS; human biomonitoring; health effects; birth outcome; environmental toxicology; ecotoxicology
Dr. Liqiong Guo

E-Mail Website
Guest Editor
Institute of Disaster Medicine, Tianjin University, Tianjin, China
Interests: In vitro diagnostic technology research; disease risk prediction; molecular epidemiology of disasters; environmental epigenetics
Special Issues, Collections and Topics in MDPI journals
Dr. Anna Justyna Klimowska

E-Mail Website
Guest Editor
Department of Toxicology, Medical University of Gdańsk, 107 Hallera St, 80-210 Gdańsk, Poland
Interests: environmental exposure; analytical toxicology

Special Issue Information

Dear Colleagues,

This Special Issue acknowledges the wide range of environmental contaminants, from persistent to non-persistent contaminants, and their potential to cause adverse health effects in the short and long terms. This Special Issue highlights the need for comprehensive human biomonitoring and exposure assessment methods that address all aspects of environmental stress—chemistry, physical, and social. It aims to draw attention to vulnerable populations around the world who are disproportionately affected by environmental pollutants. This Special Issue will serve as a call for action to ensure that these vulnerable groups are not overlooked in research, policies, and practice and that their health and well-being are prioritized.

This Special Issue will contribute to existing studies by highlighting the diverse nature of environmental exposures and their different temporal effects on health. We intend to highlight the importance of the protection of vulnerable populations and the need to address the specific challenges they face in relation to environmental exposures. We encourage the submission of research that is inclusive and involves populations that are often under-represented or neglected.

In line with the United Nations Environment Program's (UNEP) "leave no one behind" principle, this Special Issue calls for a global commitment to protect our common home—the Earth. It emphasises that in the face of environmental challenges, every individual deserves attention and care, no matter how little they are noticed or reported. We aim to create a healthier, fairer world where no one is left behind through this collective effort.

Topics of interest include, but are not limited to, the following:

  • Advancements in Human Biomonitoring Techniques: Novel methods and technologies.
  • Exposure Pathways of Persistent Organic Pollutants: Analysis and implications.
  • Non-Persistent Contaminants: Short-term exposure and health outcomes.
  • Social Determinants of Environmental Exposure: Socioeconomic status and health disparities.
  • Psychosocial Stress and Environmental Contaminants: Interactions and health effects.
  • Vulnerable Populations and Environmental Justice: Assessing and addressing disparities.
  • Emerging Challenges in Environmental Toxicology: New contaminants and health risks.
  • Regulatory Science and Policy for Exposure Control: Best practices and case studies.
  • Analytical Chemistry in Exposure Science: Breakthroughs in detection and measurement.
  • The Exposome and Public Health: Comprehensive assessment of lifetime exposures.
  • Global Trends in Environmental Contaminants: Monitoring and managing international concerns.
  • Community-Based Participatory Research in Exposure Assessment: Engaging with affected populations.
  • Educational and Behavioral Interventions for Reducing Exposure: Strategies and effectiveness.

These topics aim to cover a broad range of interests within the scope of this Special Issue, encouraging submissions that address both the scientific and societal aspects of human biomonitoring and exposure assessments. Please feel free to contact us if you require further assistance or specific descriptions for any of these topics.

Dr. Shanshan Yin
Dr. Chenye Xu
Dr. Liqiong Guo
Dr. Anna Justyna Klimowska
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • human biomonitoring

  • environmental exposure
  • pollutants
  • contamination
  • exposure
  • assessment
  • health effects
  • POPs
  • PFAS
  • emerging contaminants

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

11 pages, 902 KiB  
Article
Occurrence, Bioaccumulation, and Human Exposure Risk of the Antiandrogenic Fluorescent Dye 7-(Dimethylamino)-4-methylcoumarin and 7-(Diethylamino)-4-methylcoumarin in the Dongjiang River Basin, South China
by Yufeng Lai, Yin Huang, Danlin Yang, Jingchuan Xue, Runlin Chen, Rundong Peng, Siying Zhang, Yufei Li, Guochun Yang and Yuxian Liu
Toxics 2024, 12(12), 925; https://doi.org/10.3390/toxics12120925 - 20 Dec 2024
Viewed by 771
Abstract
Recently, 7-diethylamino-4-methylcoumarin (DEAMC) has been identified as a potent antiandrogenic compound in the surface water; however, little is known about the antiandrogenic potentials of other synthetic coumarins and their occurrence in the aquatic ecosystem. In this study, for the first time, we observed [...] Read more.
Recently, 7-diethylamino-4-methylcoumarin (DEAMC) has been identified as a potent antiandrogenic compound in the surface water; however, little is known about the antiandrogenic potentials of other synthetic coumarins and their occurrence in the aquatic ecosystem. In this study, for the first time, we observed that 7-dimethylamino-4-methylcoumarin (DAMC) elicited androgen receptor (AR) antagonistic activity with a 50% inhibitory concentration (IC50) of 1.46 µM, which is 14.3 times more potent than that observed for DEAMC (IC50 = 20.92 µM). We further collected abiotic (water and sediment) and biotic (plant, plankton, and fish) samples (n = 208) from a subtropical freshwater ecosystem, the Dongjiang River basin, in southern China, and determined the concentrations of the two coumarins in these samples. Overall, DAMC was the predominant compound found in the sediment, plant, algae, zooplankton, and fish muscle samples, with median concentrations at 0.189, 0.421, 0.832, 0.798, and 0.335 ng/g dry wt. (DW), respectively, although it was not detected in any surface water sample. For DEAMC, the median concentrations observed in the surface water, sediment, plant, algae, zooplankton, and fish muscle samples were 0.105 ng/L, 0.012, 0.051, 0.009, 0.008, and 0.181 ng/g DW, respectively. The bioaccumulation factor (BAF) values of DAMC and DEAMC in the algae, zooplankton, and fish muscle exceeded 5000 L/kg, suggesting that the two coumarins may have significant bioaccumulation potentials in aquatic biota. Additionally, the mean daily intake (EDI) of coumarins through fish consumption was estimated as 0.19 ng/kg BW/day for male toddlers. This is the first field study to illustrate the antiandrogenic potential of DAMC and document the widespread occurrence of the two synthetic coumarins in aquatic ecosystems. Full article
(This article belongs to the Special Issue Human Biomonitoring and Exposure Assessment of Environmental Contaminants)
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