Chiral Molecules - Production and Biological Properties
A special issue of Symmetry (ISSN 2073-8994). This special issue belongs to the section "Chemistry: Symmetry/Asymmetry".
Deadline for manuscript submissions: closed (31 March 2021) | Viewed by 7533
Special Issue Editor
Interests: biotransformations of organic compounds by whole cells; chemoenzymatic synthesis of optically active lactones with biological activity; determination of absolute configurations of optically active compounds; enzymatic modifications of phospholipids; analytical and spectroscopic methods to establish the structure of new compounds
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Special Issue Information
Dear Colleagues,
Constituents of living organisms are predominantly built up from chiral building blocks: e.g. L-amino acids and D-carbohydrates. Life processes therefore involve stereochemically defined molecules. Searching for new biologically active compounds both enantiomers with defined configurations of stereogenic centers should be studied separately to assess the relevance of stereoisomerism on their properties. Chiral molecules can be built by several methods that include chemical synthesis from natural chiral precursors, asymmetric synthesis using chemical chiral catalysts as well as biocatalysts – isolated free or immobilized enzymes or whole-cell biocatalysts.
For this Special Issue, contributions from new aspects of production of chiral molecules and effect of configuration of their stereogenic centers on the biological activity are welcomed.
Prof. Dr. Witold Gładkowski
Guest Editor
Manuscript Submission Information
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Keywords
- chiral molecules
- configuration of chiral centers
- biological activity
- asymmetric synthesis
- biocatalysts
- enzymes