Extraction and Determination of Antioxidant Compounds in Natural Products
A special issue of Separations (ISSN 2297-8739). This special issue belongs to the section "Analysis of Natural Products and Pharmaceuticals".
Deadline for manuscript submissions: 20 May 2026
Special Issue Editors
Interests: Interests Plant Biotechnology, Phytochemistry, Green Extraction, Medicinal Plants, Phytochemical Analysis, Allelochemicals
Special Issues, Collections and Topics in MDPI journals
Interests: Phytochemistry, Microbiology, Biotechnology, Food Science, Plant Protection and Animal Health, Cancer Research
Interests: Plant Biotechnology, Plant Breeding, Green Extraction, NADES, and the Valorization of Agricultural Products, particularly native cultivated species
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Natural products are a rich source of bioactive molecules, many of which possess potent antioxidant properties that contribute to health protection, food preservation, and pharmaceutical efficacy. With the growing interest in functional foods, nutraceuticals, and plant-based therapeutics, the precise extraction, separation, and quantification of antioxidants have become an essential aspect of analytical and natural product chemistry. In recent years, there have been increased efforts in developing efficient, selective, and sustainable analytical methodologies for the extraction, separation, and quantification of such products from complex natural matrices.
This Special Issue will focus on recent advances in sample preparation, green extraction technologies, chromatographic and spectroscopic separation methods, and novel detection techniques applied to phenolics, flavonoids, carotenoids, vitamins, and other antioxidants. We welcome contributions that address method optimization, validation, and applications of diverse natural products, as well as studies integrating chemometrics or high-throughput analysis for quality control and authentication.
Potential topics include, but are not limited to the folloing:
- Innovative extraction techniques (ultrasound-, microwave-, or supercritical fluid-assisted, deep eutectic solvents) for antioxidants.
- Advances in chromatographic, electrophoretic, and hyphenated methods (LC–MS, GC–MS, CE–MS) for antioxidant analysis.
- Spectroscopic and electrochemical approaches for rapid detection.
- Green and sustainable analytical protocols.
- Method optimization studies to enhance yield, selectivity, and reproducibility.
- Method validation, interlaboratory studies, and standardization.
- Comparative evaluations of extraction and determination methods across different matrices.
We invite researchers to submit original research articles, short communications, and review papers that present new methodologies, comparative studies, or comprehensive assessments in the field of antioxidant analysis from natural products.
Dr. Amine Elbouzidi
Dr. Mohamed Taibi
Prof. Dr. Mohamed Addi
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Separations is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antioxidants
- natural products
- extraction techniques
- green analytical chemistry
- chromatographic separation
- spectroscopic detection
- method optimization
- chemometrics
- quality control
- bioactive compounds
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