Application of Chromatographic Technology in Natural Medicine Research

Dear Colleagues,

Natural medicines, derived from plants, marine organisms, and other natural sources, represent an invaluable reservoir of chemical diversity with profound therapeutic potential. However, their complex and heterogeneous nature presents significant challenges in characterization, standardization, and quality control. This is where advanced chromatographic technologies become indispensable.

This Special Issue of Separations, titled “Application of Chromatographic Technology in Natural Medicine Research,” is dedicated to exploring the pivotal role of separation science in unlocking the secrets of natural products. We seek to highlight cutting-edge research and reviews that demonstrate the application of various chromatographic techniques—including HPLC, UHPLC, GC, SFC, TLC, and their hyphenation with mass spectrometry and other detection methods—across all facets of the field.

Topics of interest include, but are not limited to, the following:

• The discovery, separation, and identification of novel bioactive compounds.
• Metabolomics and profiling for authenticity and origin assessment.
• Innovative approaches to quality control and standardization of herbal products.
• Development of green and sustainable chromatographic methods.
• Preparative chromatography for the isolation of high-value compounds.
• Advances in chiral separations of natural products.
• Pharmacokinetic studies and bioanalysis of natural medicines.

We invite original research articles and comprehensive reviews that contribute to the advancement of chromatographic science within natural medicine research. By bringing together leading experts, this Special Issue aims at serving as a valuable resource for researchers, pharmacognosists, and analytical chemists dedicated to harnessing the power of nature for modern therapeutics.

Dr. He Ni
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Separations is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.