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Digital Signal Processing for Healthcare Applications

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biomedical Sensors".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 896

Special Issue Editor


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Guest Editor
School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian 116024, China
Interests: wearable device; biomedical signal processing; biomedical system modeling and simulation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In the era of digital health and precision medicine, healthcare applications are undergoing a transformative shift from traditional symptom-driven diagnosis to data-centric, proactive health monitoring and disease management. At the core of this technological evolution lies Digital Signal Processing (DSP), an indispensable interdisciplinary technology that integrates electrical engineering, computer science, applied mathematics and biomedical science. DSP refers to the mathematical manipulation and analysis of discrete digital signals to extract meaningful information, reduce noise interference, enhance signal characteristics and interpret underlying patterns — capabilities that have become foundational to modern healthcare systems.

The scope of DSP applications in healthcare spans the entire healthcare continuum, from non-invasive wearable health monitoring for healthy populations to clinical diagnosis, therapeutic intervention and post-treatment rehabilitation for patients with chronic diseases. For instance, DSP algorithms enable real-time analysis of cardiac signals to detect arrhythmias and myocardial ischemia, process neurological signals to identify seizure activity in epilepsy patients, and extract respiratory features to monitor sleep apnea and chronic respiratory disorders. Beyond clinical diagnostics, DSP also underpins the functionality of portable medical devices, telemedicine systems and personalized health platforms, making high-quality health assessment accessible outside of hospital settings and advancing the goal of universal healthcare equity.

In essence, DSP bridges the gap between raw physiological data and clinical decision-making in healthcare. As healthcare systems continue to embrace digitalization, miniaturization and artificial intelligence integration, the role of DSP will only grow in importance — driving innovation, improving diagnostic accuracy, reducing medical costs and ultimately elevating the quality of patient care and health outcomes. This work thus focuses on exploring the principles, methodologies and practical implementations of DSP, with a specific emphasis on its tailored applications to address key challenges in modern healthcare.

We welcome original research papers on Digital Signal Processing for Healthcare Applications.

Prof. Dr. Hong Tang
Guest Editor

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Keywords

  • biomedical engineering
  • cardiovascular signal
  • vital sign monitoring
  • wearable medical devices
  • intelligent signal analysis
  • disease diagnosis & screening

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Published Papers (1 paper)

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Research

12 pages, 1623 KB  
Article
Investigating Stress-Related Heart Rate Behavior and Rhythm in College Students Using Trend Analysis Methods
by Samira Ziyadidegan, Amir Hossein Javid and Farzan Sasangohar
Sensors 2026, 26(8), 2391; https://doi.org/10.3390/s26082391 - 14 Apr 2026
Viewed by 464
Abstract
(1) Background: Recent studies indicated the prevalence of stress among students. The increased level of stress is concerning due to its association with cardiovascular diseases. This study examined stress within the academic setting and its effects on heart rate patterns, addressing a gap [...] Read more.
(1) Background: Recent studies indicated the prevalence of stress among students. The increased level of stress is concerning due to its association with cardiovascular diseases. This study examined stress within the academic setting and its effects on heart rate patterns, addressing a gap in analysis methods beyond heart rate variability. (2) Methods: The data were collected from 125 students at a large university in Texas who were highly likely to experience stress disorders. Students were asked to wear a smartwatch for the duration of an academic semester to report their stress events. (3) Results: A total of 1513 stress events were reported. The highest frequency of stress events was reported at the beginning of the week, particularly on Tuesdays, and mostly between 10 am and 6 pm. Results also showed significant increases in the number of significant lags, the number of peaks in autocorrelation plots, and the scaling exponent in DFA plots. This indicates persistent correlations in the heart rate data and less regular, less predictable heart rate patterns and rhythms than during non-stress moments. (4) Conclusions: Findings underscore the importance of using time series analysis to understand the complexities in heart rate rhythm associated with stress, with the potential to inform future stress monitoring capabilities. Full article
(This article belongs to the Special Issue Digital Signal Processing for Healthcare Applications)
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