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Innovative Applications of Gas Sensing Technology in the Medical and Health Field

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: 25 October 2025 | Viewed by 1357

Special Issue Editor


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Guest Editor
School of General Education, Dalian University of Technology, 2 Dagong Road, Liaodongwan New District, Panjin 124221, China
Interests: gas sensors

Special Issue Information

Dear Colleagues,

In the present era with ever-changing science and technology, gas-sensing technology, with its unique advantages, has shown remarkable potential in many cutting-edge fields. Among them, its application in the medical and health field has broad development prospects.

This Special Issue focuses on the theme of "Innovative Applications of Gas Sensing Technology in the Medical and Health Field". Gas sensing technology is of great significance in disease diagnosis. It can detect biomarkers such as volatile organic compounds in human exhaled gas, providing a key basis for the early diagnosis of cancers, diabetes, respiratory diseases, etc. Meanwhile, in respiratory analysis, gas sensors can monitor the respiratory rate and changes in gas composition in real time, assisting doctors in assessing the cardiopulmonary function and metabolic status of patients.

In addition, gas sensing technology can also be applied in the process of drug research and development to monitor the drug release process in real time, ensuring the precise delivery and therapeutic effect of drugs. The research and development of new gas-sensing materials is also constantly advancing, providing support for improving the accuracy and sensitivity of medical detection. Through this Special Issue, the aim is to bring together the latest research results and practical experience, promote the in-depth application and innovative development of gas sensing technology in the medical and health field, and open new ways and directions for improving human health conditions and enhancing the level of medicine. 

Dr. Xiaofeng Wang
Guest Editor

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Keywords

  • disease diagnosis
  • respiratory analysis
  • biomarker detection
  • drug release monitoring
  • new sensing materials
  • gas-sensing mechanism

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Published Papers (2 papers)

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Research

21 pages, 4942 KiB  
Article
A New Computational Method for Detecting Leak Flow and Tidal Volume Waveforms During Spontaneous or Mandatory Breathing Assisted with Nasopharyngeal Ventilation
by Francesco Montecchia and Paola Papoff
Sensors 2025, 25(7), 2022; https://doi.org/10.3390/s25072022 - 24 Mar 2025
Viewed by 223
Abstract
Nasopharyngeal ventilation (NPV) is a common technique used to support breathing, particularly when a patient’s respiration is inadequate, such as under sedation. It involves delivering oxygen through an endotracheal tube positioned above the glottis. Accurate tidal volume measurement is crucial for anesthesiologists, with [...] Read more.
Nasopharyngeal ventilation (NPV) is a common technique used to support breathing, particularly when a patient’s respiration is inadequate, such as under sedation. It involves delivering oxygen through an endotracheal tube positioned above the glottis. Accurate tidal volume measurement is crucial for anesthesiologists, with the gold standard being a pneumotachograph. However, due to leakage from the mouth or mask, this method has limitations when applied to NPV. This study introduces a computational model that calculates respiratory flow in real time by accounting for leak flow. Results show that tidal volume measurements using this method are comparable to the gold standard, assuming the model’s assumptions hold true. Full article
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16 pages, 2629 KiB  
Article
The Development and Optimisation of a Urinary Volatile Organic Compound Analytical Platform Using Gas Sensor Arrays for the Detection of Colorectal Cancer
by Ramesh P. Arasaradnam, Ashwin Krishnamoorthy, Mark A. Hull, Peter Wheatstone, Frank Kvasnik and Krishna C. Persaud
Sensors 2025, 25(3), 599; https://doi.org/10.3390/s25030599 - 21 Jan 2025
Viewed by 880
Abstract
The profile of Volatile Organic Compounds (VOCs) may help prioritise at-risk groups for early cancer detection. Urine sampling has been shown to provide good disease accuracy whilst being patient acceptable compared to faecal analysis. Thus, in this study, urine samples were examined using [...] Read more.
The profile of Volatile Organic Compounds (VOCs) may help prioritise at-risk groups for early cancer detection. Urine sampling has been shown to provide good disease accuracy whilst being patient acceptable compared to faecal analysis. Thus, in this study, urine samples were examined using an electronic nose with metal oxide gas sensors and a solid-phase microextraction sampling system. A calibration dataset (derived from a previous study) with CRC-positive patients and healthy controls was used to train a radial basis function neural network. However, a blinded analysis failed to detect CRC accurately, necessitating an enhanced data-processing strategy. This new approach categorised samples by significant bowel diseases, including CRC and high-risk polyps. Retraining the neural network showed an area under the ROC curve of 0.88 for distinguishing CRC versus non-significant bowel disease (without CRC, polyps or inflammation). These findings suggest that, with appropriate training sets, urine VOC analysis could be a rapid, low-cost method for early detection of precancerous colorectal polyps and CRC. Full article
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