sensors-logo

Journal Browser

Journal Browser

State-of-The-Art on Enzymatic Biosensors Technology

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: closed (30 November 2020) | Viewed by 4892

Special Issue Editor

Medical School, Department of Clinical and Experimental Medicine, University of Sassari, 07100 Sassari, Italy
Interests: biosensor; biomedical applications; amperometry; biological fluids; interferents
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The need for analytical devices capable of monitoring important markers has become increasingly pressing in recent years. Among all of the analytical methods used to date, enzymatic biosensors are increasingly attracting attention because of their important features, such as sensitivity, specificity, cost-effectiveness, possible portability, and miniaturization, but, above all, for the possibility of application in the most diverse matrices. If in biomedical applications biosensors can be useful for the determination of different biomarkers, not only for diagnostic, but above all for prognostic purposes, over time, these devices can also be applied in agri-food matrices for nutraceuticals determinations, for industrial process, or even as food safety controls. In addition, it is possible to apply biosensors to environmental purposes or pharmaceutical industry for drug development or the replacement of organs.

The ever-increasing demand for the applicability of biosensors, has pushed researchers to the continuous improvement of existing systems, but also to the continuous search for new materials and strategies aimed at the construction of more and more performing devices.

So, this Special Issue aims to shed light on the recent advances in enzymatic biosensors and their multiple applications.

Potential topics include, but are not limited to, the following:

  • Polymeric films
  • Biomedical analysis
  • Food matrices’ applications
  • New materials

Prof. Dr. Gaia Rocchitta
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Polymeric films
  • Immobilizied enzymes
  • Nanoparticles
  • Enzyme stabilizers
  • Matrix interferences

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

15 pages, 2936 KiB  
Article
An Optical Urate Biosensor Based on Urate Oxidase and Long-Lifetime Metalloporphyrins
by Tokunbo Falohun and Michael J. McShane
Sensors 2020, 20(4), 959; https://doi.org/10.3390/s20040959 - 11 Feb 2020
Cited by 11 | Viewed by 4556
Abstract
Gout is a condition that affects over 8 million Americans. This condition is characterized by severe pain, and in more advanced cases, bone erosion and joint destruction. This study explores the fabrication and characterization of an optical, enzymatic urate biosensor for gout management, [...] Read more.
Gout is a condition that affects over 8 million Americans. This condition is characterized by severe pain, and in more advanced cases, bone erosion and joint destruction. This study explores the fabrication and characterization of an optical, enzymatic urate biosensor for gout management, and the optimization of the biosensor response through the tuning of hydrogel matrix properties. Sensors were fabricated through the co-immobilization of oxygen-quenched phosphorescent probes with an oxidoreductase within a biocompatible copolymer hydrogel matrix. Characterization of the spectral properties and hydrogel swelling was conducted, as well as evaluation of the response sensitivity and long-term stability of the urate biosensor. The findings indicate that increased acrylamide concentration improved the biosensor response by yielding an increased sensitivity and reduced lower limit of detection. However, the repeatability and stability tests highlighted some possible areas of improvement, with a consistent response drift observed during repeatability testing and a reduction in response seen after long-term storage tests. Overall, this study demonstrates the potential of an on-demand, patient-friendly gout management tool, while paving the way for a future multi-analyte biosensor based on this sensing platform. Full article
(This article belongs to the Special Issue State-of-The-Art on Enzymatic Biosensors Technology)
Show Figures

Figure 1

Back to TopTop