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Special Issue "Nanoparticles-Based Sensors"

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: closed (31 May 2021).

Special Issue Editors

Prof. Dr. Edelmira Valero
E-Mail Website
Guest Editor
Department of Physical Chemistry, Higher Technical School of Industrial Engineering, University of Castilla-La Mancha, Campus Universitario s/n, 02071 Albacete, Spain
Interests: electrochemical sensors and biosensors; screen-printed devices; modified electrodes; metal nanoparticles; enzymatic biosensors; electroanalysis; nanobiotechnology; electrochemistry in environmental and biological applications
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Jesús Iniesta
E-Mail Website
Guest Editor
Department of Physical Chemistry and Institute of Electrochemistry, University of Alicante, 03690 San Vicente del Raspeig, Spain
Interests: adsorption of proteins and bioelectrocatalysis; electrochemistry of carbonaceous materials; electrochemical sensors and biosensors; screen printed electrodes; electrochemistry of ionic liquids; nanoporous carbons in fuel cells; electrochemistry in environmental applications
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

One of the major challenges to be resolved by researchers is the design and development of reliable high sensitivity and low-cost sensors using novel nanoparticulate materials. The low dimensionality of nanoparticles results in excellent physicochemical properties (e.g., ease of functionalization via simple chemistry and high surface-to-volume ratios) which, allied with their unique spectral and optical properties, have prompted the development of a plethora of (bio)sensing platforms. Particularly, the incorporation of nanoparticulate materials in electrochemical devices notably provides benefits such as large specific surface area, high electrical conductivity, and low charge transfer resistance, which considerably improves electroanalytical properties such as high sensitivity and low limits of detection, among others. Nanoparticle-based sensors are gaining advantages in low cost point-of-care analysis of real samples, which involves complex sample matrices and even the need for wireless communications. For that reason, this Special Issue is intended to provide the most recent research results and emerging concepts in the challenging world of nanoparticles-based (bio)electrochemical sensors. The Special issue faces facile, sustainable scalable fabrication of nanostructured surface-based sensors using cutting-edge techniques such as screen or 3D printing technologies, looking for improving selectivity, fast response, long-term stability, and biocompatibility. Applications of nanomaterial-modified sensors for detection of relevant compounds in different fields such as the environment, clinical diagnostics, food quality control, and biowarfare are also welcome. Research papers, short communications, letters, and reviews will be considered for publication.

Therefore, potential topics include but are not limited to the following:

  • Synthesis and characterization of novel nanostructured materials for (bio)sensing applications;
  • Stability and selectivity of composite nanoparticles in complex media;
  • Long-term stability without regular maintenance;
  • New insights in synergistic phenomena in terms of sensing properties;
  • Applications of nanoparticle-based (bio)sensors.

Prof. Dr. Edelmira Valero
Prof. Dr. Jesús Iniesta
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Metal nanoparticles
  • Metal oxide nanoparticle
  • Composite nanoparticles
  • Quantum dots
  • Carbon nanoparticles
  • Nanoparticle-doped carbons
  • Nanoparticle-doped polymers
  • MOF nanoparticles
  • Decorated nanoparticles
  • Nanoparticle inks
  • 3D printing of nanoparticles
  • Electrochemical sensors and biosensors
  • Applications of nanoparticles-based (bio)sensors

Published Papers (2 papers)

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Research

Communication
Transcription-Based Amplified Colorimetric Thrombin Sensor Using Non-Crosslinking Aggregation of DNA-Modified Gold Nanoparticles
Sensors 2021, 21(13), 4318; https://doi.org/10.3390/s21134318 - 24 Jun 2021
Viewed by 591
Abstract
Gold nanoparticles (AuNPs) have been employed as colorimetric biosensors due to the color difference between their dispersed (red) and aggregated (blue) states. Although signal amplification reactions triggered by structural changes of the ligands on AuNPs have been widely used to improve measurement sensitivity, [...] Read more.
Gold nanoparticles (AuNPs) have been employed as colorimetric biosensors due to the color difference between their dispersed (red) and aggregated (blue) states. Although signal amplification reactions triggered by structural changes of the ligands on AuNPs have been widely used to improve measurement sensitivity, the use of ligands is limited. In this study, we designed a AuNP-based signal-amplifying sandwich biosensor, which does not require a conformational change in the ligands. Thrombin was used as a model target, which is recognized by two different probes. In the presence of the target, an extension reaction occurs as a result of hybridization of the two probes. Then RNA synthesis is started by RNA polymerase activation due to RNA promoter duplex formation. The amplified RNA drives aggregation or dispersion of the AuNPs, and a difference of the color if the AuNP solution is observed. As this detection system does not require a conformational change in the ligand, it can be generically applied to a wide range ligands. Full article
(This article belongs to the Special Issue Nanoparticles-Based Sensors)
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Article
Glucose Biosensor Based on Disposable Activated Carbon Electrodes Modified with Platinum Nanoparticles Electrodeposited on Poly(Azure A)
Sensors 2020, 20(16), 4489; https://doi.org/10.3390/s20164489 - 11 Aug 2020
Cited by 11 | Viewed by 1154
Abstract
Herein, a novel electrochemical glucose biosensor based on glucose oxidase (GOx) immobilized on a surface containing platinum nanoparticles (PtNPs) electrodeposited on poly(Azure A) (PAA) previously electropolymerized on activated screen-printed carbon electrodes (GOx-PtNPs-PAA-aSPCEs) is reported. The resulting electrochemical biosensor was validated towards glucose oxidation [...] Read more.
Herein, a novel electrochemical glucose biosensor based on glucose oxidase (GOx) immobilized on a surface containing platinum nanoparticles (PtNPs) electrodeposited on poly(Azure A) (PAA) previously electropolymerized on activated screen-printed carbon electrodes (GOx-PtNPs-PAA-aSPCEs) is reported. The resulting electrochemical biosensor was validated towards glucose oxidation in real samples and further electrochemical measurement associated with the generated H2O2. The electrochemical biosensor showed an excellent sensitivity (42.7 μA mM−1 cm−2), limit of detection (7.6 μM), linear range (20 μM–2.3 mM), and good selectivity towards glucose determination. Furthermore, and most importantly, the detection of glucose was performed at a low potential (0.2 V vs. Ag). The high performance of the electrochemical biosensor was explained through surface exploration using field emission SEM, XPS, and impedance measurements. The electrochemical biosensor was successfully applied to glucose quantification in several real samples (commercial juices and a plant cell culture medium), exhibiting a high accuracy when compared with a classical spectrophotometric method. This electrochemical biosensor can be easily prepared and opens up a good alternative in the development of new sensitive glucose sensors. Full article
(This article belongs to the Special Issue Nanoparticles-Based Sensors)
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